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1. 发明申请

WO2016014629A1 HIGH HEAT MONOMERS AND METHODS OF USE THEREOF 审中-公开
标题翻译：高热单体及其使用方法
公开(公告)号：WO2016014629A1
公开(公告)日：2016-01-28
申请号：PCT/US2015/041478
申请日：2015-07-22
申请人： SABIC GLOBAL TECHNOLOGIES B.V. , PETERS, Edward Norman
发明人： PETERS, Edward Norman , SISTA, Prakash
IPC分类号： C07D209/34 , C07D209/36 , C07D209/46
CPC分类号： C07D209/46 , C07C39/15 , C07C39/17 , C07C2101/14 , C07C2103/02 , C07C2103/18 , C07C2103/68 , C07C2103/86 , C07C2103/94 , C07D209/34 , C07D209/36 , C08F212/12 , C08F222/20 , C08F222/22 , C08K7/06 , C08K7/14
摘要： High heat monomer compounds, methods for preparing compounds, and compositions derived from the compounds are provided. Also provided are materials and articles derived from the compounds.
摘要翻译：提供高热单体化合物，制备化合物的方法和衍生自化合物的组合物。还提供了衍生自化合物的材料和制品。

2. 发明授权

US5811460A Water soluble fullerenes with antiviral activity 失效
标题翻译：具有抗病毒活性的水溶性富勒烯
公开(公告)号：US5811460A
公开(公告)日：1998-09-22
申请号：US184922
申请日：1994-01-24
申请人： Simon H. Friedman , Raymond F. Schinazi , Fred Wudl , Craig L. Hill , Diane L. De Camp , Rintje P. Sijbesma , George L. Kenyon
发明人： Simon H. Friedman , Raymond F. Schinazi , Fred Wudl , Craig L. Hill , Diane L. De Camp , Rintje P. Sijbesma , George L. Kenyon
IPC分类号： C07C13/64 , C07C49/255 , C07C55/00 , C07C57/50 , C07C211/27 , C07C211/42 , C07C211/50 , C07C233/36 , C07D231/56 , C07D233/54 , C07D239/26 , C07D261/08 , C07D471/10 , C07D487/10 , A61K31/215 , C07C229/32
CPC分类号： C07C57/50 , C07C13/64 , C07C211/27 , C07C211/42 , C07C211/50 , C07C233/36 , C07C49/255 , C07C55/00 , C07D231/56 , C07D233/64 , C07D239/26 , C07D261/08 , C07D471/10 , C07D487/10 , C07C2101/00 , C07C2101/14 , C07C2103/18 , C07C2103/94 , Y10S977/904
摘要： A water soluble derivative of buckministerfullerene (C.sub.60) having antiviral and virucidal properties is used to inhibit human retroviral replication and infections. The derivatized fullerene is symmetrically substituted with polar organic moieties containing 1 to 20 carbon atoms and optionally further containing oxygen or nitrogen.
摘要翻译：使用具有抗病毒和杀病毒性能的buckministerfullerene（C60）的水溶性衍生物来抑制人类逆转录病毒复制和感染。衍生的富勒烯被含有1至20个碳原子的极性有机部分对称地取代，并且任选地还含有氧或氮。

3. 发明授权

US5439942A Method of treating certain tumors using illudin analogs 失效
标题翻译：使用illudin类似物治疗某些肿瘤的方法
公开(公告)号：US5439942A
公开(公告)日：1995-08-08
申请号：US606511
申请日：1990-10-31
申请人： Michael J. Kelner , Trevor C. McMorris , Raymond Taetle
发明人： Michael J. Kelner , Trevor C. McMorris , Raymond Taetle
IPC分类号： A61K31/12 , A61K31/215 , A61K31/22 , A61K31/27 , A61P35/00 , C07C45/45 , C07C45/46 , C07C45/65 , C07C45/67 , C07C49/665 , C07C49/67 , C07C49/683 , C07C49/727 , C07C49/737 , C07C49/747 , C07C49/753 , C07C49/755 , C07C69/007 , C07C69/757 , C07C271/12
CPC分类号： C07C271/12 , A61K31/12 , A61K31/215 , A61K31/22 , A61K31/27 , C07C45/455 , C07C45/46 , C07C45/65 , C07C45/673 , C07C49/67 , C07C49/683 , C07C49/737 , C07C49/747 , C07C49/753 , C07C49/755 , C07C69/007 , C07C2103/94
摘要： A method of inhibiting certain tumor cell growth in a subject is provided comprising contacting the tumor with a therapeutic amount of an illudin S or illudin M analog having the structure ##STR1## wherein the analog is capable of inhibiting tumor cell growth without excessive toxicity to the subject and whereinR.sub.1 is hydrogen;R.sub.2 is methyl; andR.sub.3 is hydroxy.
摘要翻译：提供了抑制受试者中某些肿瘤细胞生长的方法，包括使肿瘤与治疗量的具有结构“IMAGE”的伊洛匹因S或illudin M类似物接触，其中该类似物能够抑制肿瘤细胞生长而不会对并且其中R 1是氢; R2是甲基; 并且R 3是羟基。

4. 发明授权

US5077436A Bis(3-aminophenoxy) aromatics and method of preparing the same 失效
标题翻译：双（3-氨基苯氧基）芳烃及其制备方法
公开(公告)号：US5077436A
公开(公告)日：1991-12-31
申请号：US831547
申请日：1986-02-21
申请人： Yukihiro Yoshikawa , Keizaburo Yamaguchi , Kenichi Sugimoto , Yoshimitsu Tanabe , Akihiro Yamaguchi
发明人： Yukihiro Yoshikawa , Keizaburo Yamaguchi , Kenichi Sugimoto , Yoshimitsu Tanabe , Akihiro Yamaguchi
IPC分类号： C04B7/32 , C04B7/345 , C04B28/02 , C07C205/38 , C07C217/90
CPC分类号： C07C213/02 , C07C201/12 , C07C319/20 , C07C2103/94
摘要： Bis(3-nitrophenoxy) derivatives of aromatic or bridged aromatic hydrocarbons are derived from m-dinitrobenzene and dihydroxy derivatives of said hydrocarbons and certain substituted derivatives thereof by a condensation reaction in dipolar aprotic solvents in the presence of bases. The bis(3-nitrophenoxy) derivatives and derivatives obtained are successively reduced to afford bis-(3-aminophenoxy)derivatives. This is a new method for reacting the dihydroxy-derivatives with m-dinitrobenzene, and hence can prepare novel bis(3-aminophenoxy) derivatives such as 4,4'-bis(3-amino-phenoxy)biphenyl, 1-[4-(3-aminophenoxy)phenyl]-1,3,3-trimethyl-6-(3-aminophenoxy)indan, 6,6'-bis(3-aminophenoxy)3,3,3',3'-tetramethyl-1,1'spirobiindan, and methyl substituted 2,2'-bis[4-(3-aminophenoxy)phenyl]propane.
摘要翻译：芳基或桥连芳烃的双（3-硝基苯氧基）衍生物衍生自所述烃的间二硝基苯和二羟基衍生物及其取代的衍生物，其在碱存在的情况下通过偶极非质子溶剂中的缩合反应。将所得的双（3-硝基苯氧基）衍生物和衍生物连续地还原得到双 - （3-氨基苯氧基）衍生物。这是使二羟基衍生物与间二硝基苯反应的新方法，因此可以制备新的双（3-氨基苯氧基）衍生物，如4,4'-双（3-氨基 - 苯氧基）联苯，1- [4- （3-氨基苯氧基）苯基] -1,3,3-三甲基-6-（3-氨基苯氧基）茚满，6,6'-双（3-氨基苯氧基）3,3,3'，3'-四甲基-1， 1'-螺二茚并和甲基取代的2,2'-双[4-（3-氨基苯氧基）苯基]丙烷。

5. 发明授权

US5068457A Method for making hydroxy-terminated arylene ethers 失效
标题翻译：制备羟基封端的亚芳基醚的方法
公开(公告)号：US5068457A
公开(公告)日：1991-11-26
申请号：US561403
申请日：1990-08-01
申请人： Gary W. Yeager , David N. Schissel
发明人： Gary W. Yeager , David N. Schissel
IPC分类号： C07C43/295 , C07C45/71 , C07C49/84
CPC分类号： C07C49/84 , C07C43/295 , C07C45/71 , C07C2103/94
摘要： A method for making hydroxy-terminated arylene ethers is provided by condensing an aromatic diol, such as hydroquinone with 4-fluoroacetophenone followed by a Baeyer-Villiger oxidation, and hydrolysis of the resulting diester.
摘要翻译：制备羟基封端的亚芳基醚的方法是通过将芳香族二醇如氢醌与4-氟苯乙酮缩合，接着进行Baeyer-Villiger氧化，并水解所得的二酯来提供。

6. 发明授权

US3932425A Benzospiran derivatives 失效
标题翻译： Benzospiran衍生物
公开(公告)号：US3932425A
公开(公告)日：1976-01-13
申请号：US460449
申请日：1974-04-12
申请人： Daniel Lednicer
发明人： Daniel Lednicer
IPC分类号： C07C13/72 , C07C49/675 , C07C49/683 , C07C49/697 , C07C49/747 , C07C49/755 , C07C57/50 , C07C59/54 , C07C59/86 , C07C205/45 , C07D295/02 , C07D295/033 , C07D295/096 , C07D295/135 , C07D317/22 , C07D319/08
CPC分类号： C07D319/08 , C07C205/45 , C07C247/00 , C07C45/44 , C07C49/675 , C07C49/683 , C07C49/697 , C07C49/747 , C07C49/755 , C07C57/50 , C07C59/54 , C07C59/86 , C07D295/033 , C07D295/096 , C07D295/135 , C07D317/22 , C07C2103/94
摘要： This invention relates to novel benzospiran derivatives embraced by the formula ##SPC1##Wherein the sum of A and B is at least the integer 2; A is selected from the group consisting of --(CH.sub.2).sub.n -- wherein n is 1 through 5 and --(C.sub.n H.sub.2n --.sub.2 XY)-- wherein X is selected from the group consisting of hydroxy, acetoxy, amino and acetamido and Y is hydrogen, and X when taken together with Y is selected from the group consisting of =O and =CR.sup.3 R.sup.4 wherein R.sup.3 and R.sup.4 are selected from the group consisting of hydrogen and lower alkyl of 1 through 3 carbon atoms; B is absent or --(CH.sub.2).sub.n -- wherein n is 1 through 3; R.sup.1 is selected from the group consisting of hydrogen and lower alkyl of 1 through 3 carbon atoms; R.sup.2 is selected from the group consisting of hydrogen, lower alkyl of 1 through 3 carbon atoms, ##EQU1## WHEREIN N IS 2 THROUGH 5 AND Ar is phenyl having zero through three substituents selected from the group consisting of lower alkyl of 1 through 3 carbon atoms, lower alkoxy of 1 through 3 carbon atoms, bromine, chlorine and fluorine; R.sup.1 and R.sup.2 taken together with --N
摘要翻译：本发明涉及以下式所示的新型苯并环丙兰衍生物：其中A和B的至少为整数2; A选自 - （CH 2）n - ，其中n为1至5和 - （C n H 2n-2 XY） - 其中X选自羟基，乙酰氧基，氨基和乙酰氨基，Y为氢，以及 X与Y一起选自= O和= CR 3 R 4，其中R 3和R 4选自氢和1至3个碳原子的低级烷基; B不存在或 - （CH 2）n - ，其中n为1至3; R1选自氢和1至3个碳原子的低级烷基; R 2选自氢，1至3个碳原子的低级烷基，O和 - （CH 2）n CAr，其中N为2，并且Ar为具有0至3个选自下列基团的低级烷基的苯基： 1至3个碳原子，1至3个碳原子的低级烷氧基，溴，氯和氟; R 1和R 2与-N'一起是选自未取代的和取代的吡咯烷子基，哌啶子基和六亚甲基亚氨基的饱和杂环氨基; Z选自氢，1至3个碳原子的低级烷基，1至3个碳原子的低级烷氧基，1至3个碳原子的硝基，氨基，一烷基氨基，1至4个碳原子的酰基酰胺基，溴，氯和氟; 及其药理学上可接受的酸加成盐。它还涉及制备上述新化合物（1）的中间体和方法及其新颖的衍生物。新化合物（1）对人和动物的施用抑制其中枢神经系统并降低其血压。

7. 发明申请

US20170174995A1 COMPOUND AND LIQUID-CRYSTAL COMPOSITION EMPLOYING THE SAME 审中-公开
公开(公告)号：US20170174995A1
公开(公告)日：2017-06-22
申请号：US15333583
申请日：2016-10-25
申请人： INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
发明人： Chih-Lung CHIN , Chien-Hsien CHENG , Chao-Wu LIAW , Shih-Hsien LIU , Kung-Lung CHENG
IPC分类号： C09K19/58 , C09K19/36 , C07C69/96
CPC分类号： C09K19/586 , C07C69/76 , C07C69/96 , C07C2101/14 , C07C2103/94 , C07C2601/14 , C07C2603/94 , C07D407/12 , C07D409/12 , C08F22/10 , C09K19/32 , C09K2019/0448
摘要： A compound and a liquid-crystal composition employing the same are provided. The compound has a structure represented by Formula (I) wherein Za and Zb are independently A1, A2, A3 and A4 are independently single bond, Z1, Z2, Z3, and Z4 are independently single bond, R is independently hydrogen, or C1-4 alkyl group; R1 and R2 are independently single bond, —O—(CH2)n—, —CH═CH—(CH2)2—, —(CH2)2—CH═CH—, —CH═CH—, or —C≡C—; n is an integer from 1 to 6; B1 and B2 are independently and, R3 is hydrogen, or methyl group.

8. 发明授权

US5856580A Total synthesis of antitumor acylfulvenes 失效
标题翻译：全合成抗肿瘤酰胆碱
公开(公告)号：US5856580A
公开(公告)日：1999-01-05
申请号：US961650
申请日：1997-10-31
申请人： Trevor C. McMorris
发明人： Trevor C. McMorris
IPC分类号： A61K31/335 , A61P35/00 , C07C35/37 , C07C45/29 , C07C49/633 , C07C49/733 , C07C49/737 , C07D493/08 , C07C45/57
CPC分类号： C07D493/08 , C07C35/37 , C07C49/737 , C07C2103/94 , Y02P20/55 , Y02P20/582
摘要： The present invention provides a method of synthesizing compounds of formula (I): ##STR1## wherein R and R' are independently (C.sub.1 -C.sub.4)alkyl.
摘要翻译：本发明提供了合成式（I）化合物的方法：其中R和R'独立地为（C 1 -C 4）烷基。

9. 发明授权

US5849802A Fungicidal spirocyclic amines 失效
标题翻译：杀真菌的螺环胺
公开(公告)号：US5849802A
公开(公告)日：1998-12-15
申请号：US722787
申请日：1996-09-27
申请人： Waldemar Franz Augustin Pfrengle
发明人： Waldemar Franz Augustin Pfrengle
IPC分类号： A01N31/04 , A01N33/06 , A01N43/40 , A01N43/84 , C07C45/29 , C07C45/62 , C07C45/66 , C07C49/185 , C07C49/447 , C07C49/637 , C07C211/16 , C07C211/34 , C07C217/08 , C07C217/40 , A61K31/13 , A61K31/445 , A61K31/535 , C07C211/00
CPC分类号： C07C217/40 , A01N31/04 , A01N33/06 , A01N43/40 , A01N43/84 , C07C211/16 , C07C211/34 , C07C217/08 , C07C45/29 , C07C45/62 , C07C45/66 , C07C49/185 , C07C49/447 , C07C49/637 , C07C2103/94
摘要： New antimicrobial spirocarbocyclic compounds are described, having the general formula I, ##STR1## or an acid-addition salt thereof, in which R.sub.1 represents an optionally substituted alkyl, cycloalkyl, cycloalkylalkyl, alkoxy, cycloalkoxy, alkoxyalkyl, aralkyl group R.sub.2 and R.sub.3 each independently represent hydrogen or an optionally substituted alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkylalkyl, bicycloalkyl, tricycloalkyl, alkoxyalkyl, aralkyl, aryl or haloaralkyl, a 4- to 6-membered heterocyclyl, tetrahydrofuryl or dioxolanyl group, or R.sub.2 and R.sub.3, together represents an optionally substituted, saturated or unsaturated chain which may optionally contain one or more oxygen atoms and which may optionally be aryl- or cycloalkyl-fused, and n represents zero or an integer from 1 to 3. The invention further relates to the preparation of the above spirocarbocyclic compounds, intermediates prepared during the synthesis of these compounds, compositions containing the compounds and their use as fungicides in the control of phytopathogenic fungi.
摘要翻译：描述了具有通式I，（I）或其酸加成盐的新型抗菌螺环碳环化合物，其中R 1表示任选取代的烷基，环烷基，环烷基烷基，烷氧基，环烷氧基，烷氧基烷基，芳烷基R2和 R 3各自独立地表示氢或任选取代的烷基，烯基，炔基，环烷基，环烷基烷基，二环烷基，三环烷基，烷氧基烷基，芳烷基，芳基或卤代烷基，4-至6-元杂环基，四氢呋喃基或二氧戊环基，或R 2和R 3，一起表示任选取代的饱和或不饱和的链，其可任选地含有一个或多个氧原子，并且其可以任选地被芳基或环烷基稠合，并且n表示0或1至3的整数。本发明还涉及制备的上述螺环化合物，在合成这些化合物期间制备的中间体，含有这些化合物的组合物及其用途杀真菌剂控制植物病原真菌。

10. 发明授权

US5411847A Color-photographic recording material 失效
标题翻译：彩色摄影材料
公开(公告)号：US5411847A
公开(公告)日：1995-05-02
申请号：US114130
申请日：1993-08-30
申请人： David G. Leppard , Hugh S. Laver
发明人： David G. Leppard , Hugh S. Laver
IPC分类号： G03C7/38 , C07C43/205 , C07C43/23 , C07C69/007 , C07C69/734 , C07D311/72 , C07F7/18 , G03C1/815 , G03C7/30 , G03C7/392 , G03C1/34
CPC分类号： C07C43/2055 , C07C43/23 , C07C69/007 , C07C69/734 , C07D311/72 , C07F7/1852 , G03C7/3008 , G03C7/39208 , G03C7/39232 , C07C2103/94
摘要： A color-photographic recording material is described which contains a magenta coupler and, as stabilizer, at least one compound of the formula ##STR1## where the radicals are as defined in claim 1.
摘要翻译：描述了一种彩色照相记录材料，其包含品红色成色剂和作为稳定剂的至少一种下式的化合物：其中自由基为权利要求1中限定。

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