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    • 8. 发明公开
    • A PHARMACEUTICAL PREPARATION FOR ASTHMA
    • 一种用于哮喘的药物制剂
    • EP1374881A1
    • 2004-01-02
    • EP01274052.8
    • 2001-11-01
    • Li, Hongfen
    • Li, Hongfen
    • A61K35/78A61K35/64A61K33/06A61K35/84A61P11/06
    • A61K36/8966A61K36/17A61K36/238A61K36/28A61K36/344A61K36/355A61K36/481A61K36/484A61K36/487A61K36/535A61K36/538A61K36/539A61K36/56A61K36/634A61K36/65A61K36/718A61K36/734A61K36/736A61K36/756A61K36/79A61K36/8998A61K36/904A61K2300/00
    • The present invention discloses a pharmaceutical preparation of Chinese herbal medicines which consists of Chinese herbal medicines for tonifying kidney and antiasthma, wherein the said Chinese herbal medicines comprise Perilla Frutescens, Prunus Armeniaca, Glycyrrhiza Uralensis, Scutellaria Baicalensis, Coptis Chinesis, Tusilago Farfara, Stemona Sessilifolia, Fritllaria Cirrhosa, Pheretima Aspergillum, Psoralea Corylifolia, Codonopsis Pilosula, Hordeum Vulgara, Massa Fermentata Medicalis, Schisandra Chinensis, Gypsum. The preparation has been used in China for 20 years, and in Israel for more than 5 years. It has used to treat thousands of patients suffering from asthma with the effective rate of 93%. The present preparation can relieve cough, expel phlegm, resist airway allergic inflammation reaction, improve pulmonary function, partial pressure of the oxygen in blood and increase CD 2 , CD 4 , CD 4 /CD 8 , reduce IgE in blood, and increase CAMP, reduce CGMP, stabilize mast cells, inhibit the release of histamine, which make it capable to stop the attack of asthma. As shown in observation with electron microscope, the preparation protects lung cell, increases lung cell of type 2, and recovers the vital of lungs capacity. It can be applied to the hormone dependent patients for decreasing and ceasing the administration of hormone by adjusting hypothalamic-pituitary-adrenal axis. To further demonstrate the therapeutic effect, a clinical trial carried in the Tel-Hashomer Hospital of Israel proved the preparation can improve asthma very significantly.
    • 本发明公开了一种中草药药物制剂,由中药补肾健脾和中药组成,其中所述的中草药包括紫苏子,李属杏,甘草,黄芩,黄连,法丝拉,西番荔枝 ,Fritllaria Cirrhosa,Pheretima Aspergillum,Psoralea Corylifolia,党参Pilosula,Hordeum Vulgara,Massa Fermentata Medicalis,五味子,石膏。 该制剂已在中国使用了20年,在以色列已使用了5年以上。 它曾用于治疗成千上万的哮喘患者,有效率为93%。 本制剂能减轻咳嗽,痰多,抗气道过敏性炎症反应,改善肺功能,血氧分压,增加CD2,CD4,CD4 / CD8,降低血中IgE,增加CAMP,降低CGMP,稳定 肥大细胞,抑制组胺的释放,从而使其能够阻止哮喘的发作。 如用电子显微镜观察所示,该制剂保护肺细胞,增加2型肺细胞,并恢复肺活量。 通过调整下丘脑 - 垂体 - 肾上腺轴,它可以应用于激素依赖性患者,以减少和停止激素的施用。 为了进一步证明其治疗效果,以色列Tel-Hashomer医院进行的一项临床试验证明,该制剂可显着改善哮喘。