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1. 发明申请

US20120039860A1 COMPOSITIONS AND METHODS FOR IMPROVED ORAL HEALTH 审中-公开
标题翻译：用于改善口腔健康的组合物和方法
公开(公告)号：US20120039860A1
公开(公告)日：2012-02-16
申请号：US13139787
申请日：2009-12-14
申请人： Zamzam Kabiry Roughead , Kala Marie Kaspar
发明人： Zamzam Kabiry Roughead , Kala Marie Kaspar
IPC分类号： A61K35/74 , A61P1/12 , A61P31/10 , A61P11/00 , C12N1/20 , A61P31/04
CPC分类号： A61K35/744 , A61K35/747
摘要： Compositions and methods for preventing and treating illnesses associated with oral health are provided. In a general embodiment, the compositions and methods of the present disclosure can improve oral health by reducing the incidence of aspiration pneumonia, community-acquired pneumonia and nosocomial pneumonia, allowing for less gingivitis and plaque, and providing improved tongue flora. By utilizing probiotics naturally present in the oral cavity or gastrointestinal tract, the compositions and methods in embodiments of the present disclosure can reduce anaerobic gram-negative bacilli and increase the presence of the normal flora. By preventing and treating problems associated with oral health in a patient, subsequent health problems can be prrevented or mitigated, which can result in reduced health care costs for the patient in the future.
摘要翻译：提供了预防和治疗与口腔健康有关的疾病的组合物和方法。在一般实施方案中，本公开的组合物和方法可以通过减少吸入性肺炎，社区获得性肺炎和医院内肺炎的发生率来改善口腔健康，允许较少牙龈炎和斑块，并提供改良的舌头菌群。通过利用天然存在于口腔或胃肠道中的益生菌，本公开实施方案中的组合物和方法可以减少厌氧革兰氏阴性杆菌并增加正常菌群的存在。通过预防和治疗与患者口腔健康相关的问题，可以预防或缓解随后的健康问题，这可能导致患者未来的医疗保健成本降低。

2. 发明授权

US08696568B2 Methods, system and kit for diagnosing and treating dysphagia 有权
标题翻译：用于诊断和治疗吞咽困难的方法，系统和试剂盒
公开(公告)号：US08696568B2
公开(公告)日：2014-04-15
申请号：US13144605
申请日：2009-12-07
申请人： Michael Rueben Jedwab , Zamzam Kabiry Roughead , Kala Marie Kaspar , Armando Sanchez , Christoph Hartmann , Chrystel Loret , Nathalie Martin , Jan Engmann
发明人： Michael Rueben Jedwab , Zamzam Kabiry Roughead , Kala Marie Kaspar , Armando Sanchez , Christoph Hartmann , Chrystel Loret , Nathalie Martin , Jan Engmann
IPC分类号： A61M31/00 , G09B19/00 , A23L1/05 , A23L1/0522 , A23L1/0526 , A23K1/18 , G06F19/00 , A61B5/00
CPC分类号： G06F19/3431 , A23K50/40 , A23L29/20 , A23L29/212 , A23L29/238 , A61B5/00 , A61B5/14539 , A61B5/228 , A61B5/415 , A61B5/418 , A61B5/4205 , A61B2505/03 , A61B2505/07 , A61B2505/09 , G06F19/00 , G06F19/34 , G06F19/36 , G16H10/20 , G16H15/00 , G16H50/30 , G16H50/50 , Y02A90/26 , Y10S128/92 , Y10S128/921 , Y10S128/922 , Y10S128/923 , Y10S128/924 , Y10T428/2982
摘要： Methods for evaluating and treating patients for dysphagia are provided. In a general embodiment, the method comprises screening the patient for dysphagia symptoms, diagnosing and categorizing the dysphagia if the patient exceeds a threshold of dysphagia symptoms, choosing the proper dysphagia treatment product based the patient's dysphagia, and giving the patient preparation instructions for the dysphagia treatment product.
摘要翻译：提供了评估和治疗患者吞咽困难的方法。在一般实施方案中，该方法包括筛查患者的吞咽困难症状，如果患者超过吞咽困难症状的阈值，诊断和分类吞咽困难，根据患者的吞咽困难选择适当的吞咽困难治疗产品，并给予患者吞咽困难的准备指导治疗产品。

3. 发明申请

US20120046641A1 METHODS OF DIAGNOSING AND TREATING DYSPHAGIA 有权
标题翻译：诊断和治疗精神分裂症的方法
公开(公告)号：US20120046641A1
公开(公告)日：2012-02-23
申请号：US13144605
申请日：2009-12-07
申请人： Michael Rueben Jedwab , Zamzam Kabiry Roughead , Kala Marie Kaspar , Armando Sanchez , Christoph Hartmann , Chrystel Loret , Nathalie Martin , Jan Engmann
发明人： Michael Rueben Jedwab , Zamzam Kabiry Roughead , Kala Marie Kaspar , Armando Sanchez , Christoph Hartmann , Chrystel Loret , Nathalie Martin , Jan Engmann
IPC分类号： A61M31/00 , G09B19/00
CPC分类号： G06F19/3431 , A23K50/40 , A23L29/20 , A23L29/212 , A23L29/238 , A61B5/00 , A61B5/14539 , A61B5/228 , A61B5/415 , A61B5/418 , A61B5/4205 , A61B2505/03 , A61B2505/07 , A61B2505/09 , G06F19/00 , G06F19/34 , G06F19/36 , G16H10/20 , G16H15/00 , G16H50/30 , G16H50/50 , Y02A90/26 , Y10S128/92 , Y10S128/921 , Y10S128/922 , Y10S128/923 , Y10S128/924 , Y10T428/2982
摘要： Methods for evaluating and treating patients for dysphagia are provided. In a general embodiment, the method comprises screening the patient for dysphagia symptoms, diagnosing and categorizing the dysphagia if the patient exceeds a threshold of dysphagia symptoms, choosing the proper dysphagia treatment product based the patient's dysphagia, and giving the patient preparation instructions for the dysphagia treatment product.
摘要翻译：提供了评估和治疗患者吞咽困难的方法。在一般实施方案中，该方法包括筛查患者的吞咽困难症状，如果患者超过吞咽困难症状的阈值，诊断和分类吞咽困难，根据患者的吞咽困难选择适当的吞咽困难治疗产品，并给予患者吞咽困难的准备指导治疗产品。

4. 发明申请

US20130052274A1 NUTRITIONAL COMPOSITIONS INCLUDING EXOGENOUS VITAMIN K2 审中-公开
标题翻译：营养成分包括异维生素K2
公开(公告)号：US20130052274A1
公开(公告)日：2013-02-28
申请号：US13395054
申请日：2010-09-01
申请人： Douglas Richard Bolster , Zamzam Kabiry Roughead
发明人： Douglas Richard Bolster , Zamzam Kabiry Roughead
IPC分类号： A61K33/42 , A61K33/30 , A61K33/26 , A61K33/34 , A61P21/00 , A61K31/59 , A61K38/14 , A61K31/7052 , A61P3/02 , A61P19/00 , A61K33/06 , A61K33/32
CPC分类号： A61K31/122 , A23L2/52 , A23L33/10 , A23L33/135 , A23L33/15 , A23L33/16 , A23L33/175 , A23L33/40 , A23V2002/00 , A61K31/593 , A61K33/00 , A61K33/06 , A61K33/26 , A61K33/30 , A61K33/32 , A61K33/34 , A61K33/42 , A61K45/06 , C12Q1/6883 , C12Q2600/106 , A61K2300/00 , A23V2200/306 , A23V2250/7144 , A23V2250/156
摘要： Nutritional compositions and methods of making and using the nutritional compositions are provided. In a general embodiment, the present disclosure provides a nutritional composition including exogenous vitamin K2. The nutritional compositions may further include an additional component selected from the group consisting of phosphorus, magnesium, zinc, iron, copper, manganese, calcium, vitamin D, osteopontin and combinations thereof.
摘要翻译：提供营养组合物和制备和使用营养组合物的方法。在一般实施方案中，本公开提供了包含外源维生素K2的营养组合物。营养组合物可以进一步包括选自磷，镁，锌，铁，铜，锰，钙，维生素D，骨桥蛋白及其组合的另外的组分。

5. 发明申请

US20120208893A1 NUTRITIONAL COMPOSITIONS FOR MODULATING INFLAMMATION INCLUDING EXOGENOUS VITAMIN K2 审中-公开
标题翻译：用于调节包括异维生素K2的炎症的营养组合物
公开(公告)号：US20120208893A1
公开(公告)日：2012-08-16
申请号：US13395060
申请日：2010-09-01
申请人： Douglas Richard Bolster , Zamzam Kabiry Roughead
发明人： Douglas Richard Bolster , Zamzam Kabiry Roughead
IPC分类号： A61K31/122 , A61P29/00
CPC分类号： A61K31/122 , A23L2/52 , A23L33/10 , A23L33/135 , A23L33/15 , A23L33/16 , A23L33/175 , A23L33/40 , A23V2002/00 , A61K31/593 , A61K33/00 , A61K33/06 , A61K33/26 , A61K33/30 , A61K33/32 , A61K33/34 , A61K33/42 , A61K45/06 , C12Q1/6883 , C12Q2600/106 , A61K2300/00 , A23V2200/306 , A23V2250/7144 , A23V2250/156
摘要： Nutritional compositions and methods of making and using the nutritional compositions are provided. In a general embodiment, the present disclosure provides a nutritional composition including exogenous vitamin K2. The nutritional compositions may further include an additional component selected from the group consisting of phosphorus, magnesium, zinc, iron, copper, manganese, calcium, vitamin D, osteopontin and combinations thereof.
摘要翻译：提供营养组合物和制备和使用营养组合物的方法。在一般实施方案中，本公开提供了包含外源维生素K2的营养组合物。营养组合物可以进一步包括选自磷，镁，锌，铁，铜，锰，钙，维生素D，骨桥蛋白及其组合的另外的组分。

6. 发明申请

US20120195873A1 METHODS OF ATTENUATING THE LOSS OF FUNCTIONAL STATUS 审中-公开
标题翻译：衰减功能状态损失的方法
公开(公告)号：US20120195873A1
公开(公告)日：2012-08-02
申请号：US13386209
申请日：2010-07-15
申请人： Kevin Burke Miller , Ingo Arne Jurk , Zamzam Kabiry Roughead
发明人： Kevin Burke Miller , Ingo Arne Jurk , Zamzam Kabiry Roughead
IPC分类号： A61K38/44 , A61K31/122 , A61K36/82 , A61K36/48 , A61P39/06 , A61P29/00 , A61K36/35 , A61K33/32 , A61K33/06 , A61K38/17 , A61P21/00
CPC分类号： A61K31/202 , A23L33/10 , A23L33/15 , A23L33/16 , A23L33/19 , A61K31/195 , A61K31/198 , A61K31/375 , A61K35/20 , A61K36/815 , A61K38/063 , A61K38/446 , A61K45/06 , A61K2300/00
摘要： Nutritional compositions and methods of using the nutritional compositions with exercise to attenuate the loss of functional status are provided. In a general embodiment, the present disclosure provides a nutritional composition including whey protein, and Vitamin D. The nutritional composition and exercise can be specifically used to attenuate the loss of functional status, especially in the elderly.
摘要翻译：提供营养组合物和使用营养组合物与运动的方法来减弱功能状态的丧失。在一般实施方案中，本公开提供了包含乳清蛋白和维生素D的营养组合物。营养组合物和运动可以特别用于减轻功能状态的丧失，特别是在老年人中。

7. 发明申请

US20130129838A1 NUTRITIONAL COMPOSITIONS AND METHODS FOR OPTIMIZING DIETARY ACID-BASE POTENTIAL 审中-公开
标题翻译：营养组合物和优化膳食酸碱性潜力的方法
公开(公告)号：US20130129838A1
公开(公告)日：2013-05-23
申请号：US13518296
申请日：2010-12-21
申请人： Kevin Burke Miller , Zamzam Kabiry Roughead , Jennifer Rae Mager , Douglas Richard Bolster , Norman Alan Greenberg
发明人： Kevin Burke Miller , Zamzam Kabiry Roughead , Jennifer Rae Mager , Douglas Richard Bolster , Norman Alan Greenberg
IPC分类号： A61K33/06 , G06F17/10 , A61K33/42 , A61K38/16 , A61K33/08
CPC分类号： A61K33/06 , A23L33/16 , A23L33/17 , A23L33/185 , A23L33/40 , A61K33/08 , A61K33/42 , A61K38/168 , G06F17/10
摘要： Nutritional compositions having the potential to reduce metabolic acid load and methods of making and using the nutritional compositions are provided. In an embodiment, the present disclosure provides methods of selecting and administering nutritional compositions to patients. The methods may include modifications to calculating a metabolic acid potential of a nutritional composition, calculating a base content of a nutritional composition and subtracting the base content from the acid content to determine a potential renal acid load (“PRAL”) value. The present disclosure also provides computer implemented processes for predicting PRAL values.
摘要翻译：提供了具有降低代谢酸负荷潜力的营养组合物和制备和使用营养组合物的方法。在一个实施方案中，本公开提供了向患者选择和施用营养组合物的方法。所述方法可以包括计算营养组合物的代谢酸势的修改，计算营养组合物的碱含量并从酸含量中减去碱含量以确定潜在的肾酸负载（“PRAL”）值。本公开还提供了用于预测PRAL值的计算机实现的过程。

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