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1. 发明专利

DD135972A3 未知
公开(公告)号：DD135972A3
公开(公告)日：1979-06-13
申请号：DD19283476
申请日：1976-05-14
申请人： ZAUMSEIL HANS JUERGEN , MANN WOLFGANG , WOLF HARRY , LINK FRIEDRICH
发明人： ZAUMSEIL HANS-JUERGEN , MANN WOLFGANG , WOLF HARRY , LINK FRIEDRICH
IPC分类号： B21D28/02 , B21D28/06 , B21D28/22 , B26D3/10 , H02K15/00 , H02K15/02

2. 发明专利

CS202686B1 ELECTROMOTOR SHEET METAL,METHOD OF MAKING THE SAME AND DEVICE FOR PERFORMING THE SAME 未知
公开(公告)号：CS202686B1
公开(公告)日：1981-01-30
申请号：CS312277
申请日：1977-05-12
申请人： ZAUMSEIL HANS JUERGEN , MANN WOLFGANG , WOLF HARRY , LINK FRIEDRICH
发明人： ZAUMSEIL HANS-JUERGEN , MANN WOLFGANG , WOLF HARRY , LINK FRIEDRICH
IPC分类号： B21D28/02 , B21D28/06 , B21D28/22 , B26D3/10 , H02K15/00 , H02K15/02 , B21D28/08

3. 发明专利

DD200458A1 未知
公开(公告)号：DD200458A1
公开(公告)日：1983-05-04
申请号：DD21845080
申请日：1980-01-15
申请人： KRAHL KARL , KRAHL KARL , MANN WOLFGANG , MANN WOLFGANG
发明人： KRAHL KARL , KRAHL KARL , MANN WOLFGANG DIPL-ING , MANN WOLFGANG
IPC分类号： B24C1/08

4. 发明申请

WO0204111A3 POLYMER CHIP 审中-公开
标题翻译：聚合物切片
公开(公告)号：WO0204111A3
公开(公告)日：2003-03-13
申请号：PCT/EP0107726
申请日：2001-07-05
申请人： MAX PLANCK GESELLSCHAFT , ACHTMANN MARK , KIRCHNER ROLAND , MANN WOLFGANG , MORELLI GIOVANNA , ROPERS HANS-HILGER
发明人： ACHTMANN MARK , KIRCHNER ROLAND , MANN WOLFGANG , MORELLI GIOVANNA , ROPERS HANS-HILGER
IPC分类号： C07B61/00 , C07H21/00 , C12Q1/68 , B01J19/00
CPC分类号： C07H21/00 , B01J2219/00274 , C07B2200/11 , C12Q1/6837 , C40B40/00 , C12Q2525/197 , C12Q2525/179 , C12Q2525/161
摘要： A polymer chip is disclosed, comprising a number of probes, whereby various probes are arranged at a different probe site on a support and each probe comprises an oligomer sequence. Said oligomer sequence is made up of a known number of monomers and several oligomer sequences are arranged at each probe site, each made up of a probe sequence and a wobble sequence. The probe sequences at a probe site are identical to each other and represent the probe and the wobble sequences of a probe site each comprise permutations of the monomers.
摘要翻译：公开的是，包括多个探针，其特征在于不同的探针分别设置在不同的探针点在基板上的聚合物的芯片，并且每个探针具有寡聚体序列和齐聚物序列由已知数量的单体的，并在每个探针点几寡聚物序列排列，它们是各自的探针序列和摆动序列组成，探针点的探针序列是彼此相同的并且构成探针和探针点的摆动序列具有的单体的每一种情况下的置换。

5. 发明申请

WO2007059839A9 METHOD, DEVICE AND KIT FOR STUDYING MACROMOLECULES IN A SAMPLE 审中-公开
标题翻译：方法，装置及KIT FOR大分子在样本调查
公开(公告)号：WO2007059839A9
公开(公告)日：2007-07-26
申请号：PCT/EP2006010283
申请日：2006-10-25
申请人： ADVALYTIX AG , GAUER CHRISTOPH , MANN WOLFGANG
发明人： GAUER CHRISTOPH , MANN WOLFGANG
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6837 , C12Q2565/513 , C12Q2565/543 , C12Q2537/143
摘要： The invention relates to a method for studying macromolecules in a sample, in which a support having at least one reaction centre is provided to which are bound at least two types of known macromolecules as probe molecules, macromolecules of the sample which are to be identified are labelled, the sample having at least one reaction centre is brought into contact in such a manner that a reaction between at least one type of the bound macromolecules with the identifying macromolecules can take place, when a specific reaction between macromolecules to be identified with one type of bound macromolecule is possible, unbound sample material is removed and the presence of sample macromolecules specifically bound to the at least one reaction centre is tested. The invention further relates to a device and a kit for carrying out the method of the invention and to a method for producing a device of the invention.
摘要翻译：本发明涉及一种用于大分子的样品中的分析，其中，载体设有至少一个反应中心的方法，附连到所述至少两种类型的公知的大分子作为探针分子被检测样品中的大分子标记，与所述至少一个样品反应中心是这样接触时，可存在至少一种类型的与检测的大分子结合的大分子之间的反应，当检测到的大分子之间的特异性反应是可能的与各种结合的大分子，未结合的样品材料被去除的和在存在至少一个反应位点特异性结合的样品的大分子被选中。本发明还涉及一种装置和用于根据本发明和根据本发明的制造装置的方法实施该方法的试剂盒。

6. 发明申请

WO2007036258A3 METHOD FOR THE QUANTITATIVE ANALYSIS OF THE NUMBER OF COPIES OF A PRE-DETERMINED SEQUENCE IN A CELL 审中-公开
标题翻译：定量确定细胞中优选序列的拷贝数的方法
公开(公告)号：WO2007036258A3
公开(公告)日：2007-08-09
申请号：PCT/EP2006007805
申请日：2006-08-07
申请人： ADVALYTIX AG , GAUER CHRISTOPH , MANN WOLFGANG
发明人： GAUER CHRISTOPH , MANN WOLFGANG
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6851 , C12Q2545/113 , C12Q2527/143 , C12Q2545/101
摘要： The invention relates to a method for the quantitative analysis of the number of a pre-determined sequence, and optionally of sequences homologous to the pre-determined sequence, in a biological sample, whereby a defined quantity of a biological sample is subjected to at least one amplification reaction which is adapted in such a way as to amplify at least two non-homologous sequences contained in the pre-determined sequence. The number of different amplification products obtained is then determined and compared with a frequency distribution. The invention further relates to a kit for the quantitative analysis of the number of a pre-determined sequence in a biological sample, and a device which is especially suitable for carrying out the inventive method.
摘要翻译：本发明不涉及到一种用于定量确定的预定序列的数目和可能的同源序列的预定序列的生物样品中，其中，其适于在至少两个相互的生物样品，至少一个扩增反应中，所定义的量扩增由预定序列包含的同源序列，然后确定获得的不同扩增产物的数量并与频率分布进行比较。此外，本发明涉及一种用于定量测定生物样品中预定序列的数量的试剂盒以及特别适用于实施根据本发明的方法的装置。

7. 发明申请

WO2007110390A3 INTERCHANGEABLE ACCUMULATOR UNIT 审中-公开
标题翻译：可更换蓄电池
公开(公告)号：WO2007110390A3
公开(公告)日：2008-06-26
申请号：PCT/EP2007052811
申请日：2007-03-23
申请人： SENNHEISER ELECTRONIC , ANDRES JOERG , REYMANN DIRK , MANN WOLFGANG
发明人： ANDRES JOERG , REYMANN DIRK , MANN WOLFGANG
IPC分类号： H01M10/052 , H01M10/36 , H01M10/44
CPC分类号： H01M2/1066 , H01M10/052 , H01M10/46 , H04M1/0262 , H04M1/05
摘要： The invention relates to an interchangeable accumulator unit comprising a housing (10, 20) and a lithium accumulator cell (40) which is arranged in the housing. A charging circuit (50) which controls the charging of the lithium accumulator cell (40) is also provided in the housing of the accumulator unit. At least one first charging contact unit (8100, 200) is provided on the housing.
摘要翻译：存在与壳体（10，20），并且布置在壳体锂电池单元（40）的可更换的蓄能器设置。在用于控制所述锂电池单元（40）的充电的充电累加器电路（50）的壳体还设置。至少一个第一个充电触点单元（8100，200）被设置在壳体（10，20）上。

8. 发明申请

WO2005064012A3 METHOD FOR VALIDATING AND/OR CALIBRATING A SYSTEM FOR PERFORMING HYBRIDISATION EXPERIMENTS, MICROARRAY, AND KIT THEREFOR 审中-公开
标题翻译：方法验证和/或校准SYSTEM FOR杂交实验的实施，MICRO ARRAY及其试剂盒
公开(公告)号：WO2005064012A3
公开(公告)日：2005-09-09
申请号：PCT/EP2004014414
申请日：2004-12-17
申请人： ALOPEX GMBH , MANN WOLFGANG , KRISPIN OLIVER , HOFFMUELLER PETRA
发明人： MANN WOLFGANG , KRISPIN OLIVER , HOFFMUELLER PETRA
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6837 , B01J2219/00693 , C12Q2545/107 , C12Q2527/107
摘要： The invention relates to a method for calibrating and/or validating a system for performing a microarray experiment, in addition to a microarray, and a kit therefor. The inventive method comprises the following steps: a) a microarray is prepared, said microarray comprising at least one first measuring point containing probe molecules (PM) that are complementary to the target molecules and can form, with the target molecules, hybrids that have a melting temperature Tm(PM), and at least one second measuring point containing probe molecules (MM1) that are partially complementary to the target molecules and can form, with the target molecules, partial hybrids that have a melting temperature Tm(MM1); b) target molecules are provided, that are complementary to probe molecules (PM) in at least one first measuring point of the microarray; c) a hybridisation experiment is performed with the microarray and the target molecules, with variation of a defined parameter; and d) the signal intensities are determined according to the variation of the parameter. The parameter value at the maximum difference between the signal intensities of the first and second measuring points is the parameter value for which the system is approximately in equilibrium in relation to the hybrids in the first measuring point, and according to which the system is calibrated.
摘要翻译：本发明是用于校准和/或验证用于进行微阵列实验的系统的方法以及用于其的微阵列和试剂盒。具有至少一个第一测量点在其中探针分子（PM），其互补于目标分子和可以从形式与具有的熔融温度Tm（PM）的目标分子杂交来选择 - a）提供的微阵列，包括：根据本发明的方法包括以下步骤， - 至少一个第二测量点在其中探针分子（MM1），它们不完全互补于靶分子和其可形成与目标分子，其具有的熔融温度Tm（MM1）不正确杂交其中b）以提供目标分子（探测分子PM）是互补的，以与微阵列进行杂交实验的微阵列的一个或MEH-reren第一测量点，以及c）以及在一定的参数的变化的目标分子，d）确定的信号强度作为参数的变化的函数，其中，在所述参数值是之间的最大差值SIG-nalintensitäten参数值处相对于所述第一测量点的杂交系统是大致平衡，并且该系统被校准的第一和第二测量点。

9. 发明申请

WO2008064730A3 METHOD FOR CARRYING OUT AN ENZYMATIC REACTION 审中-公开
标题翻译：进行酶反应的过程
公开(公告)号：WO2008064730A3
公开(公告)日：2008-07-24
申请号：PCT/EP2007008123
申请日：2007-09-18
申请人： ADVALYTIX AG , GAUER CHRISTOPH , MANN WOLFGANG , ALUNNI-FABBRONI MARIANNA
发明人： GAUER CHRISTOPH , MANN WOLFGANG , ALUNNI-FABBRONI MARIANNA
IPC分类号： C12Q1/68
CPC分类号： C12P7/10 , C12Q1/686 , Y02E50/16 , C12Q2565/629
摘要： The invention relates to a method for carrying out an enzymatic reaction, in particular for carrying out a polymerase chain reaction (PCR). Said method consists of the following steps: at least one eukaryotic cell is removed from a starting material; the cell core or cores of the eukaryotic cell(s) is/are coloured; at least one eukaryotic cell is deposited on a reaction point of a solid substrate in a liquid volume of less than 10 µl; it is detected whether at least one coloured cell core is present on a reaction point of the substrate, subsequently, an enzyme and optionally a reaction buffer is added to the eukaryotic cell(s) and the enzymatic reaction is subsequently started. Preferably, the claimed invention is carried out using a flow cytometer.
摘要翻译：一种用于进行PCR进行酶反应，在特定的方法，包括至少从起始原料中除去的真核细胞中，核或真核细胞（S）的核染色，沉积至少一个真核细胞以在固体底物的反应部位小于10微升的液体体积，检测是否至少一个染色的细胞核存在于衬底的一个反应位点，随后加入酶和任选的反应缓冲液的到/真核细胞（S），和酶反应的最后开始。优选地，根据本发明的方法使用流式细胞仪进行。

10. 发明申请

WO2006010610A2 METHOD FOR DETERMINING THE ABUNDANCE OF SEQUENCES IN A SAMPLE 审中-公开
标题翻译：确定样品中序列频率的方法
公开(公告)号：WO2006010610A2
公开(公告)日：2006-02-02
申请号：PCT/EP2005008156
申请日：2005-07-27
申请人： ALOPEX GMBH , ADVALYTIX AG , MANN WOLFGANG , GAUER CHRISTOPH
发明人： MANN WOLFGANG , GAUER CHRISTOPH
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6827 , C12Q1/6851 , C12Q2545/114 , C12Q2537/143
摘要： The invention relates to a method or determination of the abundance of a given sequence or several sequences identical or nearly identical to the given sequence in a sample. The method comprises the following steps: carrying out one or more amplification reactions by means of which several different sections of the sequence or sequences of the sample are amplified to give an amplified product, detection of whether given different sections of the sequence of the sample have been amplified and determination of the number of the sequence(s) in the sample by means of the abundance of the presence or otherwise of the given different sections in the amplified product.
摘要翻译：本发明涉及一种用于确定预定序列的频率或与预定序列有关的多个相同或几乎相同的样本序列的方法。该方法包括以下步骤：执行与多个所述序列或所述样品的序列的不同部分可以是一个或多个扩增反应放大到的扩增子，检测所述样品的序列的某些不同部分是否被放大，并确定序列的数目通过扩增物中特定不同部分存在或不存在的频率来确定样本中的样本。

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