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1. 发明授权

US5401778A Biodegradable plastic composition and biodegradable plastic shaped body 失效
标题翻译：生物降解塑料成分和生物降解塑料成型体
公开(公告)号：US5401778A
公开(公告)日：1995-03-28
申请号：US44386
申请日：1993-04-07
申请人： Yutaka Tokiwa , Akira Iwamoto , Masahiro Harada , Shigeki Imagawa , Teizi Urakami
发明人： Yutaka Tokiwa , Akira Iwamoto , Masahiro Harada , Shigeki Imagawa , Teizi Urakami
IPC分类号： C08L67/04 , C08G63/06 , C08G63/08
CPC分类号： C08L67/04
摘要： A biodegradable plastic composition for forming biodegradable shaped bodies which includes a poly-.beta.-hydroxybutyrate having a viscosity of n.sub.A at 185.degree. C. and a polycaprolactone having a viscosity of n.sub.B at 185.degree. C., wherein the poly-.beta.-hydroxybutyrate is present in an amount C.sub.A of 10-45 or 55-85% by weight based on the total weight of the poly-.beta.-hydroxybutyrate and the polycaprolactone, and wherein n.sub.A, n.sub.B and C.sub.A satisfy the following condition:4.times.10.sup.-3 .times.C.sub.A -1.7.ltoreq.log (n.sub.A /n.sub.B).ltoreq.4.times.10.sup.-3 .times.C.sub.A -1.3.
摘要翻译：一种用于形成可生物降解的成形体的可生物降解的塑料组合物，其包括在185℃下具有nA粘度的聚-β-羟基丁酸酯和在185℃下具有nB粘度的聚己内酯，其中存在聚-β-羟基丁酸酯基于聚-β-羟基丁酸酯和聚己内酯的总重量，其重量为10-45或55-85重量％，其中nA，nB和CA满足以下条件：4×10-3×CA-1.7 < = log（nA / nB）

2. 发明授权

US5225490A Biodisintegrable thermoplastic resin moldings and a process for producing same 失效
标题翻译：生物可降解热塑性树脂模具及其生产方法
公开(公告)号：US5225490A
公开(公告)日：1993-07-06
申请号：US609849
申请日：1990-11-07
申请人： Yutaka Tokiwa , Akira Iwamoto , Kiyoshi Takeda
发明人： Yutaka Tokiwa , Akira Iwamoto , Kiyoshi Takeda
IPC分类号： C08J5/00 , B29C47/00 , B29K67/00 , C08L67/00 , C08L67/04 , C08L101/00 , C08L101/16
CPC分类号： C08L67/00 , C08L101/00 , C08L67/04 , C08L2201/06 , Y10S525/938
摘要： Biodisintegrable thermoplastic resin moldings and a process for producing same are disclosed, the biodisintegrable thermoplastic resin moldings being comprised of a thermoplastic aliphatic polyester resin as a matrix resin having dispersed therein an other type of thermoplastic resin in a proportion of 40-75 weight % based on the whole resin. The biodisintegrable thermoplastic resin moldings is easily disintegrable after disposal in an environment where microorganisms exist so that the moldings can be reduced in bulkness and give no harmful effect on the life of natural plants and animals. Thus, the present invention affords an effective means for solving various problems in the treatment of disposed plastic articles.

3. 发明授权

US5124371A Biodegradable plastic composition, biodegradable plastic shaped body and method of producing same 失效
标题翻译：生物降解塑料成分，生物降解塑料成型体及其生产方法
公开(公告)号：US5124371A
公开(公告)日：1992-06-23
申请号：US611558
申请日：1990-11-13
申请人： Yutaka Tokiwa , Akira Iwamoto , Kiyoshi Takeda
发明人： Yutaka Tokiwa , Akira Iwamoto , Kiyoshi Takeda
IPC分类号： B29C47/00 , B29K67/00 , C08G63/08 , C08G63/78 , C08J5/00 , C08L67/00 , C08L67/04 , C08L101/16
CPC分类号： C08L67/04
摘要： A biodegradable plastic composition is disclosed which includes a polycaprolactone and a poly-.beta.-hydroxybutyrate. Disclosed also is a biodegradable plastic shaped body formed of such a composition. The shaped body may be produced by melt-mixing a blend of a polycaprolactone, a poly-.beta.-hydroxybutyrate and a copolymerization catalyst to copolymerize a portion of the polycaprolactone with a portion of the poly-.beta.-hydroxybutyrate, thereby to obtain a caprolactone/.beta.-hydroxybutyric acid copolymer-containing melt, which is subsequently shaped into a desired form.
摘要翻译：公开了一种可生物降解的塑料组合物，其包括聚己内酯和聚-β-羟基丁酸酯。还公开了由这种组合物形成的可生物降解的塑料成型体。可以通过将聚己内酯，聚-β-羟基丁酸酯和共聚催化剂的共混物熔融混合来制造成型体，以使一部分聚己内酯与一部分聚-β-羟基丁酸酯共聚，从而获得己内酯/ 含有β-羟基丁酸共聚物的熔体，随后将其成型为所需形式。

4. 发明授权

US5116880A Biodisintegrable thermoplastic resin foam and a process for producing same 失效
标题翻译：生物可降解热塑性树脂泡沫及其生产方法
公开(公告)号：US5116880A
公开(公告)日：1992-05-26
申请号：US786605
申请日：1991-11-01
申请人： Yutaka Tokiwa , Akira Iwamoto
发明人： Yutaka Tokiwa , Akira Iwamoto
IPC分类号： C08J9/14 , C08J9/00 , C08L25/04 , C08L67/00 , C08L101/00 , C08L101/16
CPC分类号： C08L101/00 , C08J9/0061 , C08L2201/06 , Y10S521/916
摘要： A biodisintegrable thermoplastic resin foam and a process for producing same are disclosed, the biodisintegrable thermoplastic resin foam being comprised as a substrate thereof a mixed resin comprising 5-40 weight % of a thermoplastic resin decomposable by microorganisms and 95-60 weight % of a thermoplastic resin not decomposable by microorganisms and being characterized in that the individual aerial cells constituting the foam have an average cell wall thickness of 1-100 .mu.m and an apparent density of 0.5 g/cm.sup.3 or less than 0.5 g/cm.sup.3. The biodisintegrable thermoplastic resin foam is easily disintegrable after disposal in an environment where microorganisms exist so that it can be reduced in bulkness and gives no harmful effect on the life of natural plants and animals. The foam incorporated with a filler can be promoted in disintegration by microorganisms. Thus the present invention affords an effective means for solving various problems in the treatment of disposed materials.

5. 发明授权

US5110838A Biodisintegrable thermoplastic resin foam and a process for producing same 失效
公开(公告)号：US5110838A
公开(公告)日：1992-05-05
申请号：US630165
申请日：1990-12-19
申请人： Yutaka Tokiwa , Akira Iwamoto
发明人： Yutaka Tokiwa , Akira Iwamoto
IPC分类号： C08J9/14 , C08J9/00 , C08L25/04 , C08L67/00 , C08L101/00 , C08L101/16
CPC分类号： C08L101/00 , C08J9/0061 , C08L2201/06 , Y10S521/916
摘要： A biodisintegrable thermoplastic resin foam and a process for producing same are disclosed, the biodisintegrable thermoplastic resin foam being comprised as a substrate thereof a mixed resin comprising 5-40 weight % of a thermoplastic resin decomposable by microorganisms and 95-60 weight % of a thermoplastic resin not decomposable by microorganisms and being characterized in that the individual aerial cells constituting the foam have an average cell wall thickness of 1-100 .mu.m and an apparent density of 0.5 g/cm.sup.3 or less than 0.5 g/cm.sup.3. The biodisintegrable thermoplastic resin foam is easily disintegrable after disposal in an environment where microorganisms exist so that it can be reduced in bulkness and gives no harmful effect on the life of natural plant and animals. The foam incorporated with a filler can be promoted in disintegration by microorganisms. Thus the present invention affords an effective means for solving various problems in the treatment of disposed materials.

6. 发明授权

US07754864B2 Tyrosinase activity controlling agent, process for producing the same and external preparation containing the same 有权
标题翻译：酪氨酸酶活性控制剂，其制备方法和含有其的外用制剂
公开(公告)号：US07754864B2
公开(公告)日：2010-07-13
申请号：US10530789
申请日：2003-10-10
申请人： Yutaka Tokiwa , Masaru Kitagawa , Kenji Yoshino , Shusaku Yanagidani , Takao Raku , Tetsuzo Totani , Hiromi Shimakawa
发明人： Yutaka Tokiwa , Masaru Kitagawa , Kenji Yoshino , Shusaku Yanagidani , Takao Raku , Tetsuzo Totani , Hiromi Shimakawa
IPC分类号： C07G3/00 , C07H15/00 , C07H17/00 , A61K31/70 , A01N43/04 , A61K8/18 , A61Q5/08 , A61Q19/02
CPC分类号： C07H15/203 , A61K8/602 , A61K31/201 , A61K31/375 , A61K31/7024 , A61K31/7034 , A61K2800/782 , A61Q5/08 , A61Q19/02 , A61Q19/08 , C07H13/06 , C12P19/46
摘要： Disclosed is a tyrosinase activity controlling agent comprising, as an active ingredient, a compound that has tyrosinase inhibiting or promoting activity, an external preparation comprising the controlling agent, and a process for producing the compound.
摘要翻译：公开了一种酪氨酸酶活性控制剂，其包含具有酪氨酸酶抑制或促进活性的化合物作为活性成分，包含所述控制剂的外用制剂及其制备方法。

7. 发明申请

US20070059828A1 Carrier for nucleic acid molecule delivery 审中-公开
标题翻译：载体用于核酸分子递送
公开(公告)号：US20070059828A1
公开(公告)日：2007-03-15
申请号：US10578283
申请日：2004-11-05
申请人： Tetsuji Yamaoka , Yutaka Tokiwa , Masaru Kitagawa
发明人： Tetsuji Yamaoka , Yutaka Tokiwa , Masaru Kitagawa
IPC分类号： C12N15/00 , C08G63/91
CPC分类号： A61K31/7088 , A61K47/34 , A61K47/61 , C08F251/00 , C12N15/87
摘要： A carrier for nucleic acid molecule delivery formed from a saccharified copolymer comprising repeating unit (A) having a cationic group, saccharified repeating unit (B). There is further provided a carrier for nucleic acid molecule delivery formed from a saccharified copolymer comprising, in addition to the repeating units (A) and (B), repeating unit (C) having a hydrophobic substituent.
摘要翻译：由包含具有阳离子基团的重复单元（A），糖化重复单元（B）的糖化共聚物形成的核酸分子递送载体。还提供了由糖化共聚物形成的用于核酸分子递送的载体，除了具有疏水性取代基的重复单元（A）和（B））外，还包含重复单元（C）。

8. 发明授权

US5859217A Process for producing polymerization sugar esters 失效
标题翻译：可聚合糖酯的制备方法
公开(公告)号：US5859217A
公开(公告)日：1999-01-12
申请号：US674810
申请日：1996-07-03
申请人： Yutaka Tokiwa , Shigeo Shibatani
发明人： Yutaka Tokiwa , Shigeo Shibatani
IPC分类号： C12P19/44 , C07H13/06 , C07H15/04 , C08B37/00 , C07H1/00
CPC分类号： C07H13/06
摘要： Disclosed are a polymerizable sugar ester of the formula shown below and a process for the production thereof:S(OH).sub.q-1 --OOC--R--COOCH.dbd.CH.sub.2wherein S(OH).sub.q-1, represents a sugar residue obtained by removing one hydroxyl group from a sugar compound composed of a sugar skeleton S and q number of hydroxyl groups bonded thereto, and R represents an alkylene group. The polymerizable sugar ester is produced by reacting a sugar compound represented by the following general formula:S(OH).sub.qwherein S represents the sugar skeleton and q is the number of the hydroxyl groups bonded thereto, with a divinyl ester of an aliphatic dicarboxylic acid represented by the following general formula:CH.sub.2 .dbd.CHOOC--R--COOCH.dbd.CH.sub.2in the presence of a hydrolytic enzyme. The polymerizable sugar ester gives a sugar-based polymer by polymerization.
摘要翻译：公开了下述式的可聚合糖酯及其制备方法：S（OH）q-1-OOC-R-COOCH = CH 2，其中S（OH）q-1表示通过除去一个由糖骨架S构成的糖化合物的羟基，q个与其键合的羟基数，R表示亚烷基。可聚合糖酯通过使由以下通式表示的糖化合物S（OH）q反应来制备：S（OH）q，其中S表示糖骨架，q表示与其键合的羟基数，表示为脂族二羧酸的二乙烯基酯通过以下通式：在水解酶的存在下，CH2 = CHOOC-R-COOCH = CH2。可聚合糖酯通过聚合得到糖基聚合物。

9. 发明授权

US5674740A Enzymatic decomposition of polycarbonate resin 失效
标题翻译：聚碳酸酯树脂的酶分解
公开(公告)号：US5674740A
公开(公告)日：1997-10-07
申请号：US559573
申请日：1995-11-16
申请人： Tetsushi Suyama , Yutaka Tokiwa
发明人： Tetsushi Suyama , Yutaka Tokiwa
IPC分类号： C12N9/20 , C08G64/42 , C08J11/04 , C08J11/22 , C08L101/16 , C12P1/04 , C12R1/38 , C12S99/00 , D06M16/00
CPC分类号： C08J11/105 , A62D3/02 , C12P1/04 , A62D2101/20 , C08J2369/00 , Y02W30/702
摘要： A polycarbonate resin, such as a poly(tetramethylene carbonate) resin, is enzymatically decomposed by contacting the polycarbonate resin with at least one enzyme selected from porcine pancreas lipase, Pseudomonas sp. lipase and Pseudomonas sp. lipoprotein lipase in the presence of water.
摘要翻译：聚碳酸酯树脂如聚（碳酸四亚甲基酯）树脂通过使聚碳酸酯树脂与选自猪胰脂肪酶，假单胞菌属（Pseudomonas sp。）的至少一种酶接触而被酶促分解。脂肪酶和假单胞菌属脂蛋白脂肪酶在水的存在下。

10. 发明申请

US20100065750A1 BURN-UP PROFILE MEASURING METHOD, BURN-UP PROFILE MEASURING APPARATUS, RADIATION SIGNAL DISTRIBUTION MEASURING APPARATUS, AND BURN-UP PROFILE MEASURING PROGRAM 有权
标题翻译：燃烧轮廓测量方法，燃烧轮廓测量装置，辐射信号分布测量装置和燃烧轮廓测量程序
公开(公告)号：US20100065750A1
公开(公告)日：2010-03-18
申请号：US12595546
申请日：2008-04-11
申请人： Hironori Kumanomido , Naotaka Oda , Yutaka Tokiwa , Makoto Ueda
发明人： Hironori Kumanomido , Naotaka Oda , Yutaka Tokiwa , Makoto Ueda
IPC分类号： G01T3/00 , G01T1/185
CPC分类号： G21C17/063 , G21Y2002/201 , G21Y2002/204 , G21Y2004/30 , G21Y2004/40
摘要： An upper detector and a lower detector that face at least one side of a fuel assembly, on which neutrons are irradiated in a nuclear reactor, and detect radiation are set at a predetermined interval in an axial direction of the fuel assembly. Distributions of radiation signals are measured by the upper detector and the lower detector while the fuel assembly and the upper detector and the lower detectors are relatively moved along the axial direction of the fuel assembly. Soundness of radiation signals measured by the upper detector and the lower detector is determined in every measurement by comparing radiation signal distributions obtained by measuring the same portion in the axial direction of the fuel assembly in a multiplexed manner with the upper detector and the lower detector. Thereafter, relative burn-up is calculated by utilizing the measured radiation signals to measure a burn-up profile. According to the present invention, it is possible to measure a burn-up profile of the fuel assembly while securing reliability of a measurement result.
摘要翻译：面向燃料组件的至少一侧的上检测器和下检测器，其中在核反应堆中辐射中子并检测辐射，沿燃料组件的轴向方向被设定为预定的间隔。辐射信号的分布由上检测器和下检测器测量，而燃料组件和上检测器和下检测器沿着燃料组件的轴向方向相对移动。通过比较通过以多路复用方式与上部检测器和下部检测器测量燃料组件的轴向方向上的相同部分而获得的辐射信号分布，在每次测量中确定由上部检测器和下部检测器测量的辐射信号的良好性。此后，通过利用测量的辐射信号来计算相对燃耗以测量燃尽曲线。根据本发明，可以在确保测量结果的可靠性的同时测量燃料组件的燃尽曲线。

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