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1. 发明申请

US20120231055A1 Polymersomes And Production Method Thereof 有权
标题翻译：聚合物及其生产方法
公开(公告)号：US20120231055A1
公开(公告)日：2012-09-13
申请号：US13512375
申请日：2010-07-12
申请人： Yuki Sugiyama , Takashi Ohmori , Nobuyoshi Koga
发明人： Yuki Sugiyama , Takashi Ohmori , Nobuyoshi Koga
IPC分类号： C08L71/02 , A61Q19/00 , A61K8/84 , C08J9/00 , A61K8/11
CPC分类号： A61K8/14 , A61K8/11 , A61K8/86 , A61K9/1273 , A61K9/14 , A61K2800/75 , A61Q19/00 , B01J13/02 , C08G18/4833 , C08G18/4837 , C08G18/4854 , Y10S977/773
摘要： It is an object of the invention to provide a polymersome excellent in the safety and feeling in use; in particular, there is no sticky feeling but there is a good refreshing feeling; and with excellent base-agent stability. A polymersome of the present invention comprises a block-type alkylene oxide derivative represented by the following formula (I) as the membrane component: R1O-[(EO)I(AO)m(EO)n]-R2 (I) wherein AO is an oxyalkylene group having 3 to 4 carbon atoms, EO is an oxyethylene group, m and 1+n are the average addition mole numbers for the oxyalkylene group and the oxyethylene group, respectively, and 1≦m≦70, 1≦1+n≦70; the percentage of the oxyethylene groups with respect to the sum of the oxyalkylene groups having 3 to 4 carbon atoms and the oxyethylene groups is 20 to 80 mass %; the addition pattern of the oxyalkylene groups having 3 to 4 carbon atoms and the oxyethylene groups is block-type; and R1 and R2 are identical or different hydrocarbon groups having 1 to 4 carbon atoms.
摘要翻译：本发明的目的是提供一种在使用上的安全性和使用感好的聚合物组合物。特别是没有粘性的感觉，但有一个很好的清爽的感觉; 并具有优异的基质稳定性。本发明的聚合物组合物包含由下式（I）表示的嵌段型烯化氧衍生物作为膜组分：R 1 O - [（EO）I（AO）m（EO）n] -R 2（I）其中AO 是具有3〜4个碳原子的氧化烯基，EO是氧化乙烯基，m和1 + n分别是氧化烯基和氧化乙烯基的平均加成摩尔数，1和nlE; m＆nlE; 70,1＆ n＆nlE; 70; 氧化乙烯基相对于具有3〜4个碳原子的氧化烯基和氧化乙烯基的总和的比例为20〜80质量％。具有3〜4个碳原子的氧化烯基和氧化乙烯基的添加图案是嵌段型; 并且R 1和R 2是具有1至4个碳原子的相同或不同的烃基。

2. 发明授权

US08603533B2 Polymersomes and production method thereof 有权
标题翻译：聚合物及其制备方法
公开(公告)号：US08603533B2
公开(公告)日：2013-12-10
申请号：US13512375
申请日：2010-07-12
申请人： Yuki Sugiyama , Takashi Ohmori , Nobuyoshi Koga
发明人： Yuki Sugiyama , Takashi Ohmori , Nobuyoshi Koga
IPC分类号： A61K8/14 , A61K8/11 , A61K8/86 , A61K9/14 , A61Q19/00 , C08G18/48
CPC分类号： A61K8/14 , A61K8/11 , A61K8/86 , A61K9/1273 , A61K9/14 , A61K2800/75 , A61Q19/00 , B01J13/02 , C08G18/4833 , C08G18/4837 , C08G18/4854 , Y10S977/773
摘要： It is an object of the invention to provide a polymersome excellent in the safety and feeling in use; in particular, there is no sticky feeling but there is a good refreshing feeling; and with excellent base-agent stability. A polymersome of the present invention comprises a block-type alkylene oxide derivative represented by the following formula (I) as the membrane component: R1O-[(EO)l(AO)m(EO)n]—R2 (I) wherein AO is an oxyalkylene group having 3 to 4 carbon atoms, EO is an oxyethylene group, m and 1+n are the average addition mole numbers for the oxyalkylene group and the oxyethylene group, respectively, and 1≦m≦70, 1≦l+n≦70; the percentage of the oxyethylene groups with respect to the sum of the oxyalkylene groups having 3 to 4 carbon atoms and the oxyethylene groups is 20 to 80 mass %; the addition pattern of the oxyalkylene groups having 3 to 4 carbon atoms and the oxyethylene groups is block-type; and R1 and R2 are identical or different hydrocarbon groups having 1 to 4 carbon atoms.
摘要翻译：本发明的目的是提供一种在使用上的安全性和使用感好的聚合物组合物。特别是没有粘性的感觉，但有一个很好的清爽的感觉; 并具有优异的基质稳定性。本发明的聚合物组合物包括由下式（I）表示的嵌段型烯化氧衍生物作为膜组分：R 1 O - [（EO）1（AO）m（EO）n] -R 2（I）其中AO 是具有3〜4个碳原子的氧化烯基，EO是氧化乙烯基，m和1 + n分别是氧化烯基和氧化乙烯基的平均加成摩尔数，和1≤n≤70,1,1+ n @ 70; 氧化乙烯基相对于具有3〜4个碳原子的氧化烯基和氧化乙烯基的总和的比例为20〜80质量％。具有3〜4个碳原子的氧化烯基和氧化乙烯基的添加图案是嵌段型; 并且R 1和R 2是具有1至4个碳原子的相同或不同的烃基。

3. 发明申请

US20100190864A1 Alkylene Oxide Derivative And Skin External Preparation Containing The Same 有权
标题翻译：含氧化烯衍生物和皮肤外用制剂
公开(公告)号：US20100190864A1
公开(公告)日：2010-07-29
申请号：US12670181
申请日：2008-07-25
申请人： Takashi Ohmori , Akira Ishikubo , Yuki Sugiyama , Yuko Matsui , Tomoyuki Kawasoe , Yoji Tezuka , Hiroyasu Mizuno , Kei-ichi Maruyama
发明人： Takashi Ohmori , Akira Ishikubo , Yuki Sugiyama , Yuko Matsui , Tomoyuki Kawasoe , Yoji Tezuka , Hiroyasu Mizuno , Kei-ichi Maruyama
IPC分类号： A61K8/86 , C07C43/15 , A61Q5/12 , A61Q1/00 , A61Q1/14 , A61Q19/10 , A61Q5/02
CPC分类号： A61Q1/02 , A61K8/86 , A61Q19/00 , C08G65/2609 , C08G65/2615 , C08G65/337 , C08L71/02
摘要： The present invention is to provide a new compound having a rough skin improving effect, excellent in safety, excellent in texture in use, especially free of sticky feeling, excellent in refreshing feeling, and capable to improve the base agent stability as a component. An alkylene oxide derivative is characterized by being represented by the below-described general formula (I): (formula I) Z-{O-[(AO)a-(EO)b]-R}2 (I) (In the formula, Z is the residue obtained by removing hydroxyl groups from the dimer diol, EO is an oxyethylene group, AO is an oxyalkylene group having 3 to 4 carbon atoms, and the addition form is block-type. The symbols a and b are the average addition mole numbers of the above-described oxyalkylene group and the oxyethylene group, respectively, and they are 1≦2 a≦150 and 1≦2 b≦150. The percentage of the oxyethylene groups with respect to the sum of the oxyalkylene groups having 3 to 4 carbon atoms and the oxyethylene groups is 10 to 99 mass %. Rs may be either identical to or different from each other, and they are hydrocarbon groups having 1 to 4 carbon atoms.)
摘要翻译：本发明提供一种具有粗糙皮肤改善效果，安全性优异，使用质地优异，特别是无粘性，清爽感好，能提高作为成分的基剂稳定性的新化合物。氧化烯衍生物的特征在于由下述通式（I）表示：（式I）Z- {O - [（AO）a-（EO）b] -R} 2（I）式中，Z为从二聚二醇中除去羟基得到的残基，EO为氧化乙烯基，AO为碳原子数3〜4的氧化烯基，添加形式为嵌段型，符号a和b为分别为上述氧化烯基和氧化乙烯基的平均加成摩尔数，它们分别为1和n 1; 2 a＆nlE; 150和1＆nlE; 2 b＆nlE; 150。氧化乙烯基相对于氧化烯基的总和的百分比具有3〜4个碳原子，氧化乙烯基为10〜99质量％，Rs可以相同也可以不同，为碳原子数1〜4的烃基）

4. 发明授权

US08232321B2 Alkylene oxide derivative and skin external preparation containing the same 有权
标题翻译：环氧丙烷衍生物和皮肤外用制剂含有
公开(公告)号：US08232321B2
公开(公告)日：2012-07-31
申请号：US12670181
申请日：2008-07-25
申请人： Takashi Ohmori , Akira Ishikubo , Yuki Sugiyama , Yuko Matsui , Tomoyuki Kawasoe , Yoji Tezuka , Hiroyasu Mizuno , Kei-ichi Maruyama
发明人： Takashi Ohmori , Akira Ishikubo , Yuki Sugiyama , Yuko Matsui , Tomoyuki Kawasoe , Yoji Tezuka , Hiroyasu Mizuno , Kei-ichi Maruyama
IPC分类号： C08G65/28 , A61K31/77 , A61K8/86 , A61Q1/02 , A61Q19/00 , A61P17/16
CPC分类号： A61Q1/02 , A61K8/86 , A61Q19/00 , C08G65/2609 , C08G65/2615 , C08G65/337 , C08L71/02
摘要： The present invention is to provide a new compound having a rough skin improving effect, excellent in safety, excellent in texture in use, especially free of sticky feeling, excellent in refreshing feeling, and capable to improve the base agent stability as a component. An alkylene oxide derivative is characterized by being represented by the below-described general formula (I): (formula I) Z—{O-[(AO)a-(EO)b]-R}2 (I) (In the formula, Z is the residue obtained by removing hydroxyl groups from the dimer diol, EO is an oxyethylene group, AO is an oxyalkylene group having 3 to 4 carbon atoms, and the addition form is block-type. The symbols a and b are the average addition mole numbers of the above-described oxyalkylene group and the oxyethylene group, respectively, and they are 1≦2 a≦150 and 1≦2 b≦150. The percentage of the oxyethylene groups with respect to the sum of the oxyalkylene groups having 3 to 4 carbon atoms and the oxyethylene groups is 10 to 99 mass %. Rs may be either identical to or different from each other, and they are hydrocarbon groups having 1 to 4 carbon atoms.)
摘要翻译：本发明提供一种具有粗糙皮肤改善效果，安全性优异，使用质地优异，特别是无粘性，清爽感好，能提高作为成分的基剂稳定性的新化合物。氧化烯衍生物的特征在于由下述通式（I）表示：（式I）Z- {O - [（AO）a-（EO）b] -R} 2（I）式中，Z为从二聚二醇中除去羟基得到的残基，EO为氧化乙烯基，AO为碳原子数3〜4的氧化烯基，添加形式为嵌段型，符号a和b为分别为上述氧化烯基和氧化乙烯基的平均加成摩尔数，它们分别为1和n 1; 2 a＆nlE; 150和1＆nlE; 2 b＆nlE; 150。氧化乙烯基相对于氧化烯基的总和的百分比具有3〜4个碳原子，氧化乙烯基为10〜99质量％，Rs可以相同也可以不同，为碳原子数1〜4的烃基）

5. 发明申请

US20100075882A1 External Skin Preparation And Skin Cleanser 审中-公开
标题翻译：外用皮肤准备和皮肤清洁剂
公开(公告)号：US20100075882A1
公开(公告)日：2010-03-25
申请号：US12443050
申请日：2007-09-28
申请人： Takashi Ohmori , Akira Ishikubo , Takashi Teshigawara , Yuki Sugiyama , Eiichiro Yagi , Kei-ichi Maruyama , Sue Taguchi , Yogi Tezuka
发明人： Takashi Ohmori , Akira Ishikubo , Takashi Teshigawara , Yuki Sugiyama , Eiichiro Yagi , Kei-ichi Maruyama , Sue Taguchi , Yogi Tezuka
IPC分类号： A61K8/86 , C08L71/02 , A61Q19/10
CPC分类号： A61Q19/00 , A61K8/90 , A61Q1/14 , A61Q19/10
摘要： The present invention was made in view of the above-described circumstances, and an object of the invention is to provide an external skin preparation having a rough skin improving effect, excellent in texture in use, especially excellent in smoothness, free of sticky feeling, and excellent in stability. Another object is to provide a skin cleanser excellent especially in usability and a cosmetic removing effect. That is, the external skin preparation of the present invention is characterized by comprising a block-type alkylene oxide derivative represented by the below-described formula (I). [formula 1] Y—[O(EO)a-(AO)b-(EO)c-R]k (I) (In the formula, Y is the residue given by removing hydroxyl groups from a polyhydric alcohol having 3 to 6 hydroxyl groups, and k is the number of hydroxyl groups of the polyhydric alcohol. EO is an oxyethylene group, AO is an oxyalkylene group having 3 to 6 carbon atoms, and they are attached in a block-type, respectively. The products, a×k, b×k, and c×k, are the average addition mole numbers of the oxyethylene group, the oxyalkylene group having 3 to 6 carbon atoms, and the oxyethylene group, respectively, and 0≦a×k≦100, 1≦b×k≦100, and 0≦c×k≦100, however, (a+c)×k>1. The percentage of all oxyethylene groups in formula (I) with respect to the sum of all oxyethylene groups and oxyalkylene groups having 3 to 6 carbon atoms in formula (I) is 10 to 80 mass %. Rs may be either identical to or different from each other, and they are hydrocarbon groups with 1 to 4 carbon atoms.) The skin cleanser of present invention is characterized by comprising 0.01 to 70 mass % of a block-type alkylene oxide derivative represented by the above-described formula (I) and 0.1 to 20 mass % of a moisturizer.
摘要翻译：本发明是鉴于上述情况而完成的，其目的在于提供一种具有粗糙的皮肤改善效果，使用性质优异，平滑性优异，无粘性的外用皮肤剂，稳定性好。另一个目的是提供一种特别优异的可用性和美容消除效果的皮肤清洁剂。也就是说，本发明的外用皮肤制剂的特征在于包含由下述式（I）表示的嵌段型烯化氧衍生物。 [式1] Y- [O（EO）a-（AO）b-（EO）cR] k（I）（式中，Y是通过从具有3至6个羟基的多元醇除去羟基而得到的残基基团，k为多元醇的羟基数，EO为氧化乙烯基，AO为碳原子数为3〜6的氧化烯基，分别以嵌段型连接，产物a× k，b×k，c×k分别为氧化乙烯基，碳原子数3〜6的氧化烯基和氧化乙烯基的平均加成摩尔数，0＆lt; nlE; a×k＆nlE; 100,1＆nlE; 式（I）中所有氧化乙烯基相对于所有氧化乙烯基和氧化烯基的总和的百分比（b + k＆nlE; 100,0和nlE; c×k＆nlE; 100，（a + c）×k> 式（I）中的碳原子数为3〜6个碳原子数为10〜80质量％，Rs可以相同也可以不同，为碳原子数1〜4的烃基。）本发明的皮肤清洁剂其特征在于，含有0.01〜70质量％的由上述式（I）表示的嵌段型烯化氧衍生物和0.1〜20质量％的保湿剂。

6. 发明申请

US20120321576A1 SUNSCREEN COMPOSITION 有权
标题翻译： SUNSCREEN组合物
公开(公告)号：US20120321576A1
公开(公告)日：2012-12-20
申请号：US13581601
申请日：2011-03-02
申请人： Yuki Sugiyama , Koji Abe , Susumu Yoshida
发明人： Yuki Sugiyama , Koji Abe , Susumu Yoshida
IPC分类号： A61K8/92 , A61Q17/04
CPC分类号： A61Q17/04 , A61K8/068 , A61K8/37 , A61K8/39 , A61K2800/596
摘要： The present invention provides a sunscreen composition comprising (a) a surfactant, (b) water, (c) an oil component, and (d) a water soluble ultraviolet absorbent and/or oil soluble ultraviolet absorbent that is in the bicontinuous microemulsion phase at 25° C.The object of the present invention is to obtain a sunscreen composition that is superior in terms of the ultraviolet protection ability and the tactile sensation during use. Furthermore, its object is to provide a sunscreen composition composed of a transparent bicontinuous microemulsion phase that spreads well when applied on the skin, is superior in terms of the coating film uniformity and absorption into the skin.
摘要翻译：本发明提供一种防晒组合物，其包含（a）表面活性剂，（b）水，（c）油组分，和（d）在双连续微乳相中的水溶性紫外线吸收剂和/或油溶性紫外线吸收剂 25℃。本发明的目的是获得在使用中在紫外线防护能力和触觉方面优异的防晒组合物。此外，其目的是提供一种防晒组合物，其由施加在皮肤上的透明双连续微乳液相组合，在涂膜均匀性和对皮肤的吸收方面优异。

7. 发明申请

US20120195841A1 Sunscreen Cosmetic 有权
标题翻译：防晒化妆品
公开(公告)号：US20120195841A1
公开(公告)日：2012-08-02
申请号：US13388446
申请日：2010-07-26
申请人： Susumu Yoshida , Koji Abe , Hideto Ueda , Yuki Sugiyama , Tomiko Takakura
发明人： Susumu Yoshida , Koji Abe , Hideto Ueda , Yuki Sugiyama , Tomiko Takakura
IPC分类号： A61K8/73 , A61Q17/04
CPC分类号： A61Q17/04 , A61K8/042 , A61K8/466 , A61K8/4946 , A61K8/73 , A61K2800/412
摘要： The present invention provides a sunscreen cosmetic comprising, relative to the total amount of the sunscreen cosmetic, 10-90 wt % of agar microgel (wherein the agar content in the agar microgel is 0.4-1 wt %) and 0.1-5 wt % of a water soluble ultraviolet absorbent.It was necessary to blend in an organic ultraviolet absorbent and such to give sunscreen cosmetics a high SPF value. However, there was a problem in that it was hard for a water soluble ultraviolet absorbent in the formulation to achieve the expected SPF function. Also, sunscreen cosmetics are particularly desired to give a freshing texture upon use.In view of the fact that a high blend ratio of an oil soluble ultraviolet absorbent inhibits the freshing texture upon use, the object of the present invention is to provide a sunscreen cosmetic that achieves a high SPF value and a freshing texture upon use by mainly blending in a water soluble ultraviolet absorbent.
摘要翻译：本发明提供了一种防晒化妆品，其相对于防晒化妆品的总量为10-90重量％的琼脂微凝胶（其中琼脂微凝胶中的琼脂含量为0.4-1重量％）和0.1-5重量％的水溶性紫外线吸收剂。需要混合有机紫外线吸收剂，使防晒化妆品具有高的SPF值。然而，存在制剂中的水溶性紫外线吸收剂难以达到预期的SPF功能的问题。此外，防晒化妆品特别期望在使用时产生新鲜的质地。考虑到油溶性紫外线吸收剂的高混合比抑制使用时的鲜嫩质地，本发明的目的是提供一种防晒化妆品，其通过主要混合使用得到高的SPF值和新鲜的质地在水溶性紫外线吸收剂中。

8. 发明授权

US08150284B2 Image forming apparatus and method for controlling image forming apparatus 有权
标题翻译：用于控制图像形成装置的图像形成装置和方法
公开(公告)号：US08150284B2
公开(公告)日：2012-04-03
申请号：US13272344
申请日：2011-10-13
申请人： Yuki Sugiyama
发明人： Yuki Sugiyama
IPC分类号： G03G15/06
CPC分类号： G03G15/0813 , G03G15/0896 , G03G15/50
摘要： An image forming apparatus is provided that reduces the occurrence of downtime in the case in which the interval between sheets needs to be expanded, and also suppresses the degradation of a photosensitive drum and a developing roller, when continuously forming images. The image forming apparatus of the present invention predicts the start timing of image formation onto the next printing material, and performs control of the positional relationship between the photosensitive drum and the developing roller without decreasing productivity, based on a result of the prediction. Further, the image forming apparatus performs control of the rotating operation of the photosensitive drum, based on the above prediction result.
摘要翻译：提供了一种图像形成装置，其在连续地形成图像时，在需要扩展片材之间的间隔的情况下减少停机的发生，并且还抑制感光鼓和显影辊的劣化。本发明的图像形成装置基于预测结果预测图像形成到下一个打印材料上的开始定时，并且不降低生产率来执行感光鼓和显影辊之间的位置关系的控制。此外，图像形成装置基于上述预测结果来执行感光鼓的旋转操作的控制。

9. 发明申请

US20120071568A1 Cosmetic Composition 审中-公开
标题翻译：化妆品组成
公开(公告)号：US20120071568A1
公开(公告)日：2012-03-22
申请号：US13321245
申请日：2010-05-19
申请人： Yuki Sugiyama , Kei Watanabe , Yoshihito Nishijima
发明人： Yuki Sugiyama , Kei Watanabe , Yoshihito Nishijima
IPC分类号： A61K8/06 , A61Q5/02 , A61Q1/14 , A61Q19/10
CPC分类号： A61Q5/02 , A61K8/0295 , A61K8/04 , A61K8/31 , A61K8/342 , A61K8/37 , A61K8/375 , A61K8/39 , A61K8/891 , A61K8/922 , A61K2800/48 , A61Q1/14 , A61Q5/10 , A61Q5/12 , A61Q19/00 , A61Q19/10
摘要： An object of the invention is to provide a cosmetic composition that is not drippy during makeup removal, has good skin spreadability during use, has a refreshing feeling in use, and provides a high cleansing effect, and in particular, to provide a cleansing composition. The cosmetic composition according to the invention is characterized by comprising (A) an alkyl ethylene oxide surfactant having an HLB of 8 to 13, (B) 10 to 40 mass % of an oil component, and (C) water, wherein the composition is a discontinuous-micellar cubic liquid-crystal phase. Also the cosmetic composition is characterized by comprising the above composition as the outer phase and (B2) an oil phase comprising an oil component, that is different from the oil component (B1) captured in said discontinuous-micellar cubic liquid-crystal phase, as the inner phase.
摘要翻译：本发明的目的是提供一种化妆品组合物，其在卸妆过程中不滴落，在使用过程中具有良好的皮肤铺展性，使用时具有清爽感，并提供高清洁效果，特别是提供清洁组合物。本发明的化妆品组合物的特征在于：（A）HLB为8〜13，（B）10〜40质量％的油性成分的烷基环氧乙烷表面活性剂和（C）水，其中，不连续的胶束立方液晶相。另外，化妆品组合物的特征还在于，将上述组合物作为外相，（B2）含有油成分的油相，与油墨成分（B1）不同，捕获在所述不连续胶束型立方晶相中，作为内相。

10. 发明申请

US20100124427A1 IMAGE FORMING APPARATUS AND METHOD FOR CONTROLLING IMAGE FORMING APPARATUS 有权
标题翻译：图像形成装置和控制图像形成装置的方法
公开(公告)号：US20100124427A1
公开(公告)日：2010-05-20
申请号：US12612918
申请日：2009-11-05
申请人： Yuki Sugiyama
发明人： Yuki Sugiyama
IPC分类号： G03G15/08
CPC分类号： G03G15/0813 , G03G15/0896 , G03G15/50
摘要： An image forming apparatus is provided that reduces the occurrence of downtime in the case in which the interval between sheets needs to be expanded, and also suppresses the degradation of a photosensitive drum and a developing roller, when continuously forming images. The image forming apparatus of the present invention predicts the start timing of image formation onto the next printing material, and performs control of the positional relationship between the photosensitive drum and the developing roller without decreasing productivity, based on a result of the prediction. Further, the image forming apparatus performs control of the rotating operation of the photosensitive drum, based on the above prediction result.
摘要翻译：提供了一种图像形成装置，其在连续地形成图像时，在需要扩展片材之间的间隔的情况下减少停机的发生，并且还抑制感光鼓和显影辊的劣化。本发明的图像形成装置基于预测结果预测图像形成到下一个打印材料上的开始定时，并且不降低生产率来执行感光鼓和显影辊之间的位置关系的控制。此外，图像形成装置基于上述预测结果来执行感光鼓的旋转操作的控制。

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