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1. 发明申请

US20050120084A1 Method of and system for creating, maintaining, and utilizing an online universal address book 审中-公开
标题翻译：用于创建，维护和利用在线通用通讯录的方法和系统
公开(公告)号：US20050120084A1
公开(公告)日：2005-06-02
申请号：US10973283
申请日：2004-10-27
申请人： Yu Hu , Dan Qiu
发明人： Yu Hu , Dan Qiu
IPC分类号： G06F7/00 , G06F15/16 , G06F17/30 , G06Q10/00 , G06Q30/00
CPC分类号： H04L67/1095 , G06Q10/107 , G06Q30/02 , H04L67/306
摘要： A method for creating and maintaining a social network system using a computer system includes constructing a first database for storing identification information and a second database for storing contact information of a user, the second database being connected to the first database; receiving registration from users in the computer system, the registration containing identification and contact information of the users; sending invitation initiated by a first user to a second user specified by the first user; if the second user accepts the invitation, creating a direct link between these two users, the direct link allowing the two users to access the other's contact information. The method may further include creating an address book containing identification information and contact information of users that are directly connected to a user A for the user A. Any amendment of the information of a user initiated by the user who is directly connected to user A will be reflected in user A's address book. The invention also provides a computer system for implementing the method for creating and maintaining the social network system.
摘要翻译：一种使用计算机系统创建和维护社交网络系统的方法包括构建用于存储识别信息的第一数据库和用于存储用户的联系人信息的第二数据库，第二数据库连接到第一数据库; 在计算机系统中接收用户的注册，包含用户的身份和联系信息的注册; 将由第一用户发起的邀请发送给由第一用户指定的第二用户; 如果第二个用户接受邀请，则在这两个用户之间创建直接链接，直接链接允许两个用户访问对方的联系人信息。该方法还可以包括创建包含与用户A直接连接到用户A的用户的标识信息和联系人信息的地址簿。用户直接连接到用户A的用户发起的用户的信息的任何修改将会反映在用户A的通讯录中。本发明还提供一种用于实现用于创建和维护社交网络系统的方法的计算机系统。

2. 发明申请

US20120018912A1 METHOD OF PREPARING NANO-DISPERSED HIGH-ALL-TRANS-CAROTENOID MICROCAPSULES 有权
标题翻译：制备纳米分散高转移CAROTENOID微球的方法
公开(公告)号：US20120018912A1
公开(公告)日：2012-01-26
申请号：US13259291
申请日：2010-03-18
申请人： Zhirong Chen , Jianfeng Chen , Hong Yin , Hong Zhao , Dan Qiu , Lifang Shi , Jiandong Li , Guangwen Chu , Lei Shao
发明人： Zhirong Chen , Jianfeng Chen , Hong Yin , Hong Zhao , Dan Qiu , Lifang Shi , Jiandong Li , Guangwen Chu , Lei Shao
IPC分类号： B29B9/12
CPC分类号： B01J13/043 , A23K20/179 , A23L5/44 , A23L33/10 , A23L33/105 , A23P10/30 , A23V2002/00 , A61K8/0241 , A61K8/11 , A61K8/31 , A61K8/35 , A61K31/01 , A61K31/122 , A61K2800/412 , A61Q19/00 , C09B61/00 , C09B67/0097 , A23V2250/211 , A23V2200/224
摘要： A method of preparing nano-dispersed high-all-trans-carotenoid microcapsules is provided, comprising: preparing 10-20% carotenoid suspension by milling the high-all trans-carotenoid crystals with dichloromethane until the particle size thereof is in the range of 2-5 μm, then supplying the suspension together with preheated dichloromethane of another pass into a dissolving tank to obtain a solution of 0.5-2%; delivering the solution together with ethanol or isopropanol into a crystallization device having high gravity rotating packed bed simultaneously and continuously, and then into a wiped-film evaporator for desolvation until the solid content is 10-20%, then a transparent alcohol dispersion of carotenoid is obtained; mashing the alcohol dispersion together with an aqueous solution containing an antioxidant and protective colloid and spray drying to obtain nano-dispersed high-all-trans-carotenoid microcapsules. As the crystals are nano-dispersed and the content of trans-isomer is more than 90%, the carotenoid microcapsules of present inventions exhibit high bioavailability.
摘要翻译：提供了一种制备纳米分散高全反式类胡萝卜素微胶囊的方法，包括：通过用二氯甲烷研磨高全反式类胡萝卜素晶体制备10-20％的类胡萝卜素悬浮液，直到其粒径在2 -5μm，然后将悬浮液与另一道次的预热二氯甲烷一起供入溶解槽中，得到0.5-2％的溶液; 将溶液与乙醇或异丙醇一起输送到具有高重力旋转填充床的结晶装置中，同时且连续地进行，然后进入擦膜蒸发器进行去溶剂化直到固体含量为10-20％，然后将类胡萝卜素的透明醇分散体获得; 将醇分散体与含有抗氧化剂和保护胶体的水溶液一起糖化并喷雾干燥，得到纳米分散的高全反式类胡萝卜素微胶囊。由于晶体是纳米分散的并且反式异构体的含量大于90％，本发明的类胡萝卜素微胶囊显示出高的生物利用度。

3. 发明授权

US08540908B2 Method of preparing nano-dispersed high-all-trans-carotenoid microcapsules 有权
标题翻译：制备纳米分散高全反式类胡萝卜素微胶囊的方法
公开(公告)号：US08540908B2
公开(公告)日：2013-09-24
申请号：US13259291
申请日：2010-03-18
申请人： Zhirong Chen , Jianfeng Chen , Hong Yin , Hong Zhao , Dan Qiu , Lifang Shi , Jiandong Li , Guangwen Chu , Lei Shao
发明人： Zhirong Chen , Jianfeng Chen , Hong Yin , Hong Zhao , Dan Qiu , Lifang Shi , Jiandong Li , Guangwen Chu , Lei Shao
IPC分类号： B01J13/04
CPC分类号： B01J13/043 , A23K20/179 , A23L5/44 , A23L33/10 , A23L33/105 , A23P10/30 , A23V2002/00 , A61K8/0241 , A61K8/11 , A61K8/31 , A61K8/35 , A61K31/01 , A61K31/122 , A61K2800/412 , A61Q19/00 , C09B61/00 , C09B67/0097 , A23V2250/211 , A23V2200/224
摘要： A method of preparing nano-dispersed high-all-trans-carotenoid microcapsules is provided, comprising: preparing 10-20% carotenoid suspension by milling the high-all trans-carotenoid crystals with dichloromethane until the particle size thereof is in the range of 2-5 μm, then supplying the suspension together with preheated dichloromethane of another pass into a dissolving tank to obtain a solution of 0.5-2%; delivering the solution together with ethanol or isopropanol into a crystallization device having high gravity rotating packed bed simultaneously and continuously, and then into a wiped-film evaporator for desolvation until the solid content is 10-20%, then a transparent alcohol dispersion of carotenoid is obtained; mashing the alcohol dispersion together with an aqueous solution containing an antioxidant and protective colloid and spray drying to obtain nano-dispersed high-all-trans-carotenoid microcapsules. As the crystals are nano-dispersed and the content of trans-isomer is more than 90%, the carotenoid microcapsules of present inventions exhibit high bioavailability.
摘要翻译：提供了一种制备纳米分散高全反式类胡萝卜素微胶囊的方法，包括：通过用二氯甲烷研磨高全反式类胡萝卜素晶体制备10-20％的类胡萝卜素悬浮液，直到其粒径在2 -5μm，然后将悬浮液与另一道次的预热二氯甲烷一起供入溶解槽中，得到0.5-2％的溶液; 将溶液与乙醇或异丙醇一起输送到具有高重力旋转填充床的结晶装置中，同时且连续地进行，然后进入擦膜蒸发器进行去溶剂化直到固体含量为10-20％，然后将类胡萝卜素的透明醇分散体获得; 将醇分散体与含有抗氧化剂和保护胶体的水溶液一起糖化并喷雾干燥，得到纳米分散的高全反式类胡萝卜素微胶囊。由于晶体是纳米分散的并且反式异构体的含量大于90％，本发明的类胡萝卜素微胶囊显示出高的生物利用度。

4. 发明授权

US09173818B2 Method for preparing stable-type vitamin A microcapsules continuously 有权
标题翻译：连续制备稳定型维生素A微胶囊的方法
公开(公告)号：US09173818B2
公开(公告)日：2015-11-03
申请号：US13980126
申请日：2011-03-25
申请人： Hong Yin , Jianfeng Chen , Zhirong Chen , Jiexin Wang , Yong Qi , Hong Zhao , Lifang Shi , Dan Qiu
发明人： Hong Yin , Jianfeng Chen , Zhirong Chen , Jiexin Wang , Yong Qi , Hong Zhao , Lifang Shi , Dan Qiu
IPC分类号： A61J3/07 , A61K9/00 , B29B9/12 , A61K9/16 , A61K9/50 , A61K31/07 , A61K9/51
CPC分类号： A61J3/07 , A61K9/1652 , A61K9/1694 , A61K9/5036 , A61K9/5089 , A61K9/5161 , A61K31/07
摘要： A method for continuously preparing stable-type vitamin A microcapsules is disclosed. The method comprises the following steps: adding vitamin A crystals and an antioxidant into a crystal melter continuously according to a certain ratio under the protection of nitrogen to prepare vitamin A melting oil containing the antioxidant; pumping the above melting oil into a high gravity rotary packed bed emulsifier with a liquid distributor by a pump, and pumping aqueous solution containing gellable modified starch into the above high gravity rotary packed bed emulsifier after deoxidation treatment to obtain vitamin A emulsion at the outlet of the high gravity rotary packed bed emulsifier; and atomizing and spraying the emulsion continuously in a cooled starch bed for granulating, and performing fluidization drying and gelation treatment in a fluidized bed by taking nitrogen as a drying medium to obtain the stable-type vitamin A microcapsules. Above method has the advantage of capability of continuous production, and has good embedding effect due to adopting the gellable modified starch, granulating and gelation treatment, thus the product has good storage stability.
摘要翻译：公开了连续制备稳定型维生素A微胶囊的方法。该方法包括以下步骤：在氮保护下，以一定的比例将维生素A晶体和抗氧化剂连续添加到晶体熔化器中，制备含有抗氧化剂的维生素A熔融油; 通过泵将上述熔融油泵送到具有液体分配器的高重力旋转填充床乳化剂中，并且在脱氧处理之后将含有可凝胶改性淀粉的水溶液泵送到上述高重力旋转填充床乳化剂中以在出口处获得维生素A乳液高重力旋转填充床乳化剂; 并在冷却的淀粉床中连续雾化和喷雾乳液进行造粒，并通过以氮气作为干燥介质在流化床中进行流化干燥和凝胶化处理，得到稳定型维生素A微胶囊。上述方法具有连续生产能力的优点，由于采用可凝胶改性淀粉，造粒和凝胶化处理，具有良好的包埋效果，因此产品具有良好的储存稳定性。

5. 发明申请

US20140001662A1 METHOD FOR PREPARING STABLE-TYPE VITAMIN A MICROCAPSULES CONTINUOUSLY 有权
标题翻译：连续制备稳定型维生素一微生物的方法
公开(公告)号：US20140001662A1
公开(公告)日：2014-01-02
申请号：US13980126
申请日：2011-03-25
申请人： Hong Yin , Jianfeng Chen , Zhirong Chen , Jiexin Wang , Yong Qi , Hong Zhao , Lifang Shi , Dan Qiu
发明人： Hong Yin , Jianfeng Chen , Zhirong Chen , Jiexin Wang , Yong Qi , Hong Zhao , Lifang Shi , Dan Qiu
IPC分类号： A61J3/07
CPC分类号： A61J3/07 , A61K9/1652 , A61K9/1694 , A61K9/5036 , A61K9/5089 , A61K9/5161 , A61K31/07
摘要： A method for continuously preparing stable-type vitamin A microcapsules is disclosed. The method comprises the following steps: adding vitamin A crystals and an antioxidant into a crystal melter continuously according to a certain ratio under the protection of nitrogen to prepare vitamin A melting oil containing the antioxidant; pumping the above melting oil into a high gravity rotary packed bed emulsifier with a liquid distributor by a pump, and pumping aqueous solution containing gellable modified starch into the above high gravity rotary packed bed emulsifier after deoxidation treatment to obtain vitamin A emulsion at the outlet of the high gravity rotary packed bed emulsifier; and atomizing and spraying the emulsion continuously in a cooled starch bed for granulating, and performing fluidization drying and gelation treatment in a fluidized bed by taking nitrogen as a drying medium to obtain the stable-type vitamin A microcapsules. Above method has the advantage of capability of continuous production, and has good embedding effect due to adopting the gellable modified starch, granulating and gelation treatment, thus the product has good storage stability.
摘要翻译：公开了连续制备稳定型维生素A微胶囊的方法。该方法包括以下步骤：在氮保护下，以一定的比例将维生素A晶体和抗氧化剂连续添加到晶体熔化器中，制备含有抗氧化剂的维生素A熔融油; 通过泵将上述熔融油泵送到具有液体分配器的高重力旋转填充床乳化剂中，并且在脱氧处理之后将含有可凝胶改性淀粉的水溶液泵送到上述高重力旋转填充床乳化剂中以在出口处获得维生素A乳液高重力旋转填充床乳化剂; 并在冷却的淀粉床中连续雾化和喷雾乳液进行造粒，并通过以氮气作为干燥介质在流化床中进行流化干燥和凝胶化处理，得到稳定型维生素A微胶囊。上述方法具有连续生产能力的优点，由于采用可凝胶改性淀粉，造粒和凝胶化处理，具有良好的包埋效果，因此产品具有良好的储存稳定性。

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