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1. 发明授权

US08023732B2 Accelerated image registration by means of parallel processors 有权
标题翻译：通过并行处理器加速图像配准
公开(公告)号：US08023732B2
公开(公告)日：2011-09-20
申请号：US11780971
申请日：2007-07-20
申请人： Yu Deuerling-Zheng , Christian Eisenacher , Adam K. Galant , Joachim Hornegger , Marc Stamminger
发明人： Yu Deuerling-Zheng , Christian Eisenacher , Adam K. Galant , Joachim Hornegger , Marc Stamminger
IPC分类号： G06K9/00
CPC分类号： G06T7/238 , G06T7/32 , G06T7/33 , G06T2200/28 , G06T2207/10116 , G06T2207/30101
摘要： A method is provided for accelerating non-rigid image registration, using parallel processors. To that end, on a commercially available graphics card, a block-matching algorithm is implemented, which, by histogram-based similarity standards, calculates the motion vectors for individual blocks. All the blocks are processed simultaneously and individually. The complete motion vector field is obtained by bilinear interpolation. Optimized search methods, such as conjugate direction searching, are employed. The algorithm terminates once the optimal displacement has been found for all the blocks. The registration is done completely on the graphics card. The algorithm is fully automatic, precise, and fast. The program may be employed for instance in registration for digital subtraction angiography.
摘要翻译：提供了一种使用并行处理器加速非刚性图像配准的方法。为此，在市售的图形卡上，实现了块匹配算法，其通过基于直方图的相似性标准来计算各个块的运动矢量。所有的块被同时和单独处理。通过双线性插值获得完整的运动矢量场。采用优化的搜索方法，如共轭方向搜索。一旦找到所有块的最佳位移，算法就会终止。注册完全在图形卡上完成。该算法全自动，精确，快速。该程序可以用于例如用于数字减影血管造影术的注册。

2. 发明申请

US20090062641A1 Method and system for catheter detection and tracking in a fluoroscopic image sequence 失效
标题翻译：荧光镜图像序列中导管检测和跟踪的方法和系统
公开(公告)号：US20090062641A1
公开(公告)日：2009-03-05
申请号：US12221732
申请日：2008-08-06
申请人： Adrian Barbu , Wei Zhang , Norbert Strobel , Adam K. Galant , Ulrich Bill , Dorin Comaniciu
发明人： Adrian Barbu , Wei Zhang , Norbert Strobel , Adam K. Galant , Ulrich Bill , Dorin Comaniciu
IPC分类号： A61B5/05
CPC分类号： A61B34/20 , A61B2090/376
摘要： A method and system for detecting and tracking an ablation catheter tip in a fluoroscopic image sequence is disclosed. Catheter tip candidates are detected in each frame of the fluoroscopic image sequence using marginal space learning. The detected catheter tip candidates are then tracked over all the frames of the fluoroscopic image sequence in order to determine an ablation catheter tip location in each frame.
摘要翻译：公开了一种用于在透视图像序列中检测和跟踪消融导管尖端的方法和系统。使用边缘空间学习在荧光镜像图像序列的每个帧中检测导管尖端候选。然后在荧光镜像图像序列的所有帧上跟踪检测到的导管尖端候选，以便确定每个帧中的消融导管尖端位置。

3. 发明申请

US20100061608A1 Medical Image Data Processing and Interventional Instrument Identification System 有权
标题翻译：医学图像数据处理和介入仪器识别系统
公开(公告)号：US20100061608A1
公开(公告)日：2010-03-11
申请号：US12552883
申请日：2009-09-02
申请人： Adam K. Galant
发明人： Adam K. Galant
IPC分类号： G06K9/00
CPC分类号： G06T7/11 , G06T7/194 , G06T2207/10116 , G06T2207/20012
摘要： A system processes pixel representative image data of medical images of patient anatomy to automatically identify an interventional instrument. The system includes an acquisition processor that receives pixel luminance data comprising multiple sequential medical images of a patient anatomical portion and luminance data of an individual image comprises multiple pixel luminance representative values of multiple individual pixels of the individual image. An image data processor detects and subtracts background image data from the pixel luminance data comprising the multiple sequential medical images to provide processed pixel luminance data comprising multiple processed sequential medical images. The image data processor computes gradient components of individual pixels of the processed pixel luminance data. The image data processor modifies the computed gradient component data by suppressing computed gradient components lacking symmetry about an interventional instrument width dimension and filters the modified computed gradient component data for use in providing image representative data showing the interventional instrument.
摘要翻译：系统处理患者解剖结构的医学图像的像素代表性图像数据，以自动识别介入器械。该系统包括采集处理器，其接收包括患者解剖部分的多个连续医学图像的像素亮度数据，并且个体图像的亮度数据包括个体图像的多个单独像素的多个像素亮度代表值。图像数据处理器从包括多个连续医学图像的像素亮度数据中检测和减去背景图像数据，以提供包括多个经处理的顺序医学图像的经处理的像素亮度数据。图像数据处理器计算经处理的像素亮度数据的各个像素的梯度分量。图像数据处理器通过抑制计算出的关于介入仪器宽度尺寸对称性的梯度分量来修改所计算的梯度分量数据，并且对经修改的计算出的梯度分量数据进行滤波，以用于提供示出介入仪器的图像代表性数据。

4. 发明授权

US08396533B2 Method and system for catheter detection and tracking in a fluoroscopic image sequence 失效
公开(公告)号：US08396533B2
公开(公告)日：2013-03-12
申请号：US12221732
申请日：2008-08-06
申请人： Adrian Barbu , Wei Zhang , Norbert Strobel , Adam K. Galant , Ulrich Bill , Dorin Comaniciu
发明人： Adrian Barbu , Wei Zhang , Norbert Strobel , Adam K. Galant , Ulrich Bill , Dorin Comaniciu
IPC分类号： A61B5/05
CPC分类号： A61B34/20 , A61B2090/376
摘要： A method and system for detecting and tracking an ablation catheter tip in a fluoroscopic image sequence is disclosed. Catheter tip candidates are detected in each frame of the fluoroscopic image sequence using marginal space learning. The detected catheter tip candidates are then tracked over all the frames of the fluoroscopic image sequence in order to determine an ablation catheter tip location in each frame.

5. 发明授权

US08290234B2 System for removing static background detail from medical image sequences 有权
标题翻译：用于从医学图像序列中去除静态背景细节的系统
公开(公告)号：US08290234B2
公开(公告)日：2012-10-16
申请号：US12536727
申请日：2009-08-06
申请人： Adam K. Galant
发明人： Adam K. Galant
IPC分类号： G06K9/00
CPC分类号： G06K9/4609 , G06K2209/057 , G06T7/11 , G06T7/174 , G06T7/194 , G06T2207/20012
摘要： A system determines static background medical image data by receiving pixel luminance data comprising multiple sequential medical images of a patient anatomical portion and luminance data of an individual image that comprises multiple pixel luminance representative values of multiple individual pixels of the individual image. A filter includes a first filter function having a first response time for filtering received luminance representative values of a particular individual pixel varying in response to a first motion disturbance in the multiple sequential medical images for use in identifying a substantially minimum luminance value of the particular individual pixel in the multiple sequential medical images. The filter filters luminance representative values of individual pixels of the multiple sequential medical images to identify substantially minimum luminance values of individual pixels in the multiple sequential medical images as background image data of the multiple sequential medical images.
摘要翻译：系统通过接收像素亮度数据来确定静态背景医学图像数据，所述像素亮度数据包括患者解剖部分的多个连续医学图像和包括个体图像的多个像素的多个像素亮度代表值的单个图像的亮度数据。滤波器包括第一滤波器功能，其具有第一响应时间，用于滤波响应于多个连续医学图像中的第一运动干扰而变化的特定个体像素的接收亮度代表值，用于识别特定个体的基本上最小亮度值像素在多个顺序的医学图像。滤波器滤除多个顺序医学图像的各个像素的亮度代表值，以将多个连续医学图像中的各个像素的基本上最小的亮度值识别为多个顺序医学图像的背景图像数据。

6. 发明授权

US07773719B2 Model-based heart reconstruction and navigation 有权
标题翻译：基于模型的心脏重建和导航
公开(公告)号：US07773719B2
公开(公告)日：2010-08-10
申请号：US12054622
申请日：2008-03-25
申请人： Adam K. Galant , Dorin Comaniciu
发明人： Adam K. Galant , Dorin Comaniciu
IPC分类号： A61B6/00
CPC分类号： A61B6/032 , A61B6/503 , A61B6/504 , A61B6/5235 , A61B90/36 , A61B2017/00703 , A61B2090/367 , G06F19/00 , G06T7/0012 , G06T2207/10081 , G06T2207/30048
摘要： A method to obtain a patient based organ model from patient data, having steps of obtaining a computerized organ model based upon at least one data set of patients, the computerized organ model having a set of classifiers that are used to determine physical parameters of the patients heart, placing the patient in a diagnostic scanner device, taking representative data images of a patients organ while changing position of the image scan, the data images taken with ECG synchronization; and preparing the patient based organ model by evaluating the representative data images of the patients organ with the set of classifiers in the computerized organ model.
摘要翻译：一种从患者数据获得基于患者的器官模型的方法，具有基于至少一个患者数据集获得计算机化器官模型的步骤，所述计算机化器官模型具有用于确定患者的物理参数的一组分类器心脏，将患者放置在诊断扫描仪装置中，在改变图像扫描的位置的同时拍摄患者器官的代表性数据图像，用ECG同步拍摄的数据图像; 并通过在计算机化器官模型中评估具有一组分类器的患者器官的代表性数据图像来准备基于患者的器官模型。

7. 发明申请

US20080200876A1 Needle Guidance With a Dual-Headed Laser 有权
标题翻译：针头引导与双头激光
公开(公告)号：US20080200876A1
公开(公告)日：2008-08-21
申请号：US11829345
申请日：2007-07-27
申请人： Markus Kukuk , Adam K. Galant , Sandy Napel
发明人： Markus Kukuk , Adam K. Galant , Sandy Napel
IPC分类号： A61M5/158
CPC分类号： A61M5/427 , A61B90/11 , A61B2018/2025 , A61B2090/376
摘要： Disclosed are method and apparatus for guiding a needle during an interventional radiology procedure. The target and skin entry point are pre-determined in three-dimensional medical imaging scans. The needle trajectory is defined by the target and skin entry point, which is physically marked on the skin. A dual-headed laser emitting two laser beams is positioned and aligned such that one laser beam is aimed at the skin entry point and the other laser beam is aimed at an external reference point, which is determined such that the axis of the laser beam aimed at the skin entry point is substantially collinear with the needle trajectory. The needle is inserted while maintaining the axis of the needle substantially collinear with the axis of the laser beam aimed at the skin entry point.
摘要翻译：公开了在介入放射学过程中引导针的方法和装置。目标和皮肤入口点在三维医学成像扫描中是预先确定的。针轨迹由目标和皮肤入口点定义，物理标记在皮肤上。发射两个激光束的双头激光被定位和对准，使得一个激光束瞄准皮肤入口点，而另一个激光束瞄准外部参考点，其被确定为使得激光束的轴线瞄准皮肤入口点与针迹线基本上共线。插入针，同时保持针的轴线基本上与瞄准皮肤入口点的激光束的轴线共线。

8. 发明授权

US09370627B2 Needle guidance with a dual-headed laser 有权
标题翻译：用双头激光针引导
公开(公告)号：US09370627B2
公开(公告)日：2016-06-21
申请号：US11829345
申请日：2007-07-27
申请人： Markus Kukuk , Adam K. Galant , Sandy Napel
发明人： Markus Kukuk , Adam K. Galant , Sandy Napel
IPC分类号： A61B5/05 , A61M5/42 , A61B18/20
CPC分类号： A61M5/427 , A61B90/11 , A61B2018/2025 , A61B2090/376
摘要： Disclosed are method and apparatus for guiding a needle during an interventional radiology procedure. The target and skin entry point are pre-determined in three-dimensional medical imaging scans. The needle trajectory is defined by the target and skin entry point, which is physically marked on the skin. A dual-headed laser emitting two laser beams is positioned and aligned such that one laser beam is aimed at the skin entry point and the other laser beam is aimed at an external reference point, which is determined such that the axis of the laser beam aimed at the skin entry point is substantially collinear with the needle trajectory. The needle is inserted while maintaining the axis of the needle substantially collinear with the axis of the laser beam aimed at the skin entry point.
摘要翻译：公开了在介入放射学过程中引导针的方法和装置。目标和皮肤入口点在三维医学成像扫描中是预先确定的。针轨迹由目标和皮肤入口点定义，物理标记在皮肤上。发射两个激光束的双头激光被定位和对准，使得一个激光束瞄准皮肤入口点，而另一个激光束瞄准外部参考点，其被确定为使得激光束的轴线瞄准皮肤入口点与针迹线基本上共线。插入针，同时保持针的轴线基本上与瞄准皮肤入口点的激光束的轴线共线。

9. 发明授权

US08244013B2 Medical image data processing and interventional instrument identification system 有权
标题翻译：医学图像数据处理和介入仪器识别系统
公开(公告)号：US08244013B2
公开(公告)日：2012-08-14
申请号：US12552883
申请日：2009-09-02
申请人： Adam K. Galant
发明人： Adam K. Galant
IPC分类号： G06K9/00
CPC分类号： G06T7/11 , G06T7/194 , G06T2207/10116 , G06T2207/20012
摘要： A system processes pixel representative image data of medical images of patient anatomy to automatically identify an interventional instrument. The system includes an acquisition processor that receives pixel luminance data comprising multiple sequential medical images of a patient anatomical portion and luminance data of an individual image comprises multiple pixel luminance representative values of multiple individual pixels of the individual image. An image data processor detects and subtracts background image data from the pixel luminance data comprising the multiple sequential medical images to provide processed pixel luminance data comprising multiple processed sequential medical images. The image data processor computes gradient components of individual pixels of the processed pixel luminance data. The image data processor modifies the computed gradient component data by suppressing computed gradient components lacking symmetry about an interventional instrument width dimension and filters the modified computed gradient component data for use in providing image representative data showing the interventional instrument.
摘要翻译：系统处理患者解剖结构的医学图像的像素代表性图像数据，以自动识别介入器械。该系统包括采集处理器，其接收包括患者解剖部分的多个连续医学图像的像素亮度数据，并且个体图像的亮度数据包括个体图像的多个单独像素的多个像素亮度代表值。图像数据处理器从包括多个连续医学图像的像素亮度数据中检测和减去背景图像数据，以提供包括多个经处理的顺序医学图像的经处理的像素亮度数据。图像数据处理器计算经处理的像素亮度数据的各个像素的梯度分量。图像数据处理器通过抑制计算出的关于介入仪器宽度尺寸对称性的梯度分量来修改所计算的梯度分量数据，并且对经修改的计算出的梯度分量数据进行滤波，以用于提供示出介入仪器的图像代表性数据。

10. 发明申请

US20100111389A1 SYSTEM AND METHOD FOR PLANNING AND GUIDING PERCUTANEOUS PROCEDURES 审中-公开
标题翻译：用于规划和指导程序的系统和方法
公开(公告)号：US20100111389A1
公开(公告)日：2010-05-06
申请号：US12329657
申请日：2008-12-08
申请人： Norbert Strobel , Adam K. Galant , Liron Yatziv
发明人： Norbert Strobel , Adam K. Galant , Liron Yatziv
IPC分类号： G06K9/00 , G01N23/04 , H05G1/60 , G06T15/00
CPC分类号： A61B6/12 , A61B6/027 , A61B6/4441 , A61B6/5217 , A61B6/5235 , A61B6/5247 , G06T19/00 , G06T2210/41 , G06T2219/028
摘要： A system and method are disclosed for planning a percutaneous procedure and for guiding an instrument to engage a target within a patient's body. A patient 3-dimensional image data set is provided, within which a user selects a skin entry point and a target point. A line, or “planned path,” is generated between the points which is used to align a movable arm to achieve a “Bull's Eye View,” in which the two points are superimposed. The instrument is placed at the skin entry point and aligned using the Bull's Eye View along a desired trajectory that intersects the target. Initial alignment is verified using fluoroscopy. Progression fluoroscopic views are used during the insertion procedure to ensure the instrument remains on the planned path. When the instrument reaches the target, a procedure may be performed, such as a biopsy, a drainage procedure, a radiofrequency ablation, or other medical interventional procedure.
摘要翻译：公开了一种用于规划经皮程序和引导器械使患者身体内的目标接合的系统和方法。提供了一种患者的三维图像数据集，用户在其中选择皮肤入口点和目标点。在用于对准可移动臂以实现“Bull's Eye View”的点之间产生线或“计划路径”，其中两个点被叠加。将仪器放置在皮肤入口点，并使用Bull's Eye View沿着与目标相交的所需轨迹对齐。使用荧光透视验证初始对准。在插入过程中使用进展荧光透视图，以确保仪器保持在计划的路径上。当仪器到达目标时，可以执行程序，例如活检，排水程序，射频消融或其他医疗介入程序。

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