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1. 发明授权

US09269144B2 Method and apparatus for motion correction and image enhancement for optical coherence tomography 有权
标题翻译：用于光学相干断层扫描的运动校正和图像增强的方法和装置
公开(公告)号：US09269144B2
公开(公告)日：2016-02-23
申请号：US13097785
申请日：2011-04-29
申请人： Martin F. G. Kraus , Benjamin M. Potsaid , James G. Fujimoto , Markus Anton Mayer , Ruediger Bock , Joachim Hornegger
发明人： Martin F. G. Kraus , Benjamin M. Potsaid , James G. Fujimoto , Markus Anton Mayer , Ruediger Bock , Joachim Hornegger
IPC分类号： G06T7/00 , A61B3/10
CPC分类号： G06T11/006 , A61B3/0025 , A61B3/102 , G06T7/248 , G06T7/30 , G06T2207/10101 , G06T2207/30041
摘要： Images of an object, such as OCT scans of a human eye, can include distortions and data gaps due to relative motion of the object and the image acquisition device. Methods and systems for correction of such distortions and data gaps are described herein. Motion-corrected data is arrived at by applying three-dimensional transforms to input three-dimensional data sets that represent at least partially overlapping regions of the imaged object. The three dimensional transforms are computed based on an objective function that accounts for similarity between the transformed three-dimensional data sets and the estimated motion of the object relative to an imaging instrument. Methods and systems described herein advantageously eliminate the need for postulated assumptions and reliance on landmarks and are capable of filling data gaps, thereby producing high quality, undistorted images of objects subject to movement during imaging. Multiple motion-corrected data sets can be merged or combined to produce a data set with improved image quality.
摘要翻译：诸如人眼的OCT扫描的物体的图像可能包括由于物体和图像采集装置的相对运动引起的失真和数据间隙。本文描述了用于校正这种失真和数据间隙的方法和系统。通过应用三维变换来输入表示成像对象的至少部分重叠区域的三维数据集来获得运动校正数据。基于目标函数来计算三维变换，该目标函数考虑了变换的三维数据集之间的相似性以及物体相对于成像仪器的估计的运动。本文描述的方法和系统有利地消除了对假定假设和对地标的依赖的需要，并且能够填补数据间隙，从而产生在成像期间经受运动的物体的高质量，未失真的图像。可以将多个运动校正数据集合或组合以产生具有改进的图像质量的数据集。

2. 发明授权

US08183529B2 Method for three-dimensional presentation of a moved structure using a tomographic method 有权
标题翻译：使用断层摄影法对移动结构进行三维显示的方法
公开(公告)号：US08183529B2
公开(公告)日：2012-05-22
申请号：US12378793
申请日：2009-02-19
申请人： Joachim Hornegger , Günter Lauritsch , Marcus Prümmer , Christopher Rohkohl
发明人： Joachim Hornegger , Günter Lauritsch , Marcus Prümmer , Christopher Rohkohl
IPC分类号： G01T1/20 , G06K9/00 , A61N5/10
CPC分类号： A61B6/032 , A61B6/4441 , A61B6/466 , G06T11/005 , G06T2211/412
摘要： The invention relates to a method for three-dimensional presentation of a moved structure using a tomographic method, in which a plurality of projection images are recorded from different imaging angles between a start angle with a start node point and an end angle with an end node point by an imaging unit during a number of rotation passes, with three-dimensional image data being able to be reconstructed from the projection images, with the projection images being spaced by a path or an edge. For determining the three-dimensional presentation for each angle of projection only those projection images are selected which minimize the sum of the paths or weighted edges between adjacent projection angles for a gating.
摘要翻译：本发明涉及一种使用断层摄影方法对移动结构进行三维呈现的方法，其中从与起点节点的开始角度与终端节点的终止角度之间的不同成像角度记录多个投影图像在多次旋转通过期间由成像单元指向，其中三维图像数据能够从投影图像重建，其中投影图像被路径或边缘间隔开。为了确定每个投影角度的三维呈现，仅选择那些最小化用于门控的相邻投影角之间的路径或加权边缘之和的投影图像。

3. 发明授权

US07848498B2 Operating method for a support facility for a medical engineering system and objects corresponding herewith 有权
标题翻译：用于医疗工程系统的支持设施的操作方法和与之对应的对象
公开(公告)号：US07848498B2
公开(公告)日：2010-12-07
申请号：US11297062
申请日：2005-12-08
申请人： Joachim Hornegger , Elmar Nöth
发明人： Joachim Hornegger , Elmar Nöth
IPC分类号： H04M11/00 , A61B1/04
CPC分类号： A61B6/467 , A61B6/4441 , A61B6/462 , A61B34/10 , A61B90/00 , A61B90/20 , A61B90/90 , A61B2017/00017 , A61B2017/00115 , G06F19/00 , G16H40/63
摘要： An inquirer provides a support facility for a medical engineering system with a voice entry by means of a voice entry device. The support facility evaluates the voice entry by means of a voice recognition system and reacts correspondingly in that it outputs an acoustic output to the inquirer via an acoustic output device and an optical output via an optical device.
摘要翻译：查询者通过语音输入设备为具有语音输入的医疗工程系统提供支持设施。支持设施通过语音识别系统来评估语音输入，并且相应地进行反应，其中通过声学输出设备和经由光学设备的光学输出向询问者输出声学输出。

4. 发明授权

US07822291B2 Non-rigid multi-modal registration using statistical learning methods 有权
标题翻译：使用统计学习方法的非刚性多模态注册
公开(公告)号：US07822291B2
公开(公告)日：2010-10-26
申请号：US11259560
申请日：2005-10-26
申请人： Christoph Guetter , Chenyang Xu , Joachim Hornegger , Frank Sauer
发明人： Christoph Guetter , Chenyang Xu , Joachim Hornegger , Frank Sauer
IPC分类号： G06K9/32
CPC分类号： G06K9/6206 , G06T7/33 , G06T7/35 , G06T2200/04 , G06T2207/10072 , G06T2207/20221
摘要： A computer-implemented method for non-rigid multi-modal registration, includes providing trained data corresponding to previously registered images captured by different modalities, receiving two or more images captured by the different modalities, and registering the two or more images according to context information determined based on the trained data.
摘要翻译：一种用于非刚性多模式注册的计算机实现的方法，包括提供对应于由不同模态捕获的先前注册的图像的训练数据，接收由不同模态捕获的两个或多个图像，以及根据上下文信息注册两个或多个图像根据训练数据确定。

5. 发明申请

US20090214098A1 Method for three-dimensional presentation of a moved structure using a tomographic method 有权
标题翻译：使用断层摄影法对移动结构进行三维显示的方法
公开(公告)号：US20090214098A1
公开(公告)日：2009-08-27
申请号：US12378793
申请日：2009-02-19
申请人： Joachim Hornegger , Gunter Lauritsch , Marcus Prummer , Christopher Rohkohl
发明人： Joachim Hornegger , Gunter Lauritsch , Marcus Prummer , Christopher Rohkohl
IPC分类号： G06K9/00
CPC分类号： A61B6/032 , A61B6/4441 , A61B6/466 , G06T11/005 , G06T2211/412
摘要： The invention relates to a method for three-dimensional presentation of a moved structure using a tomographic method, in which a plurality of projection images are recorded from different imaging angles between a start angle with a start node point and an end angle with an end node point by an imaging unit during a number of rotation passes, with three-dimensional image data being able to be reconstructed from the projection images, with the projection images being spaced by a path or an edge. For determining the three-dimensional presentation for each angle of projection only those projection images are selected which minimize the sum of the paths or weighted edges between adjacent projection angles for a gating.
摘要翻译：本发明涉及一种使用断层摄影方法对移动结构进行三维呈现的方法，其中从与起点节点的开始角度与终端节点的终止角度之间的不同成像角度记录多个投影图像在多次旋转通过期间由成像单元指向，其中三维图像数据能够从投影图像重建，其中投影图像被路径或边缘间隔开。为了确定每个投影角度的三维呈现，仅选择这些投影图像，其最小化门控的相邻投影角之间的路径或加权边缘之和。

6. 发明申请

US20090016592A1 Method for correcting truncation artifacts 有权
标题翻译：截断伪影的校正方法
公开(公告)号：US20090016592A1
公开(公告)日：2009-01-15
申请号：US12217650
申请日：2008-07-08
申请人： Stefan Hoppe , Joachim Hornegger , Gunter Lauritsch
发明人： Stefan Hoppe , Joachim Hornegger , Gunter Lauritsch
IPC分类号： G06K9/00 , A61B6/00
CPC分类号： A61B6/032 , A61B6/027 , A61B6/466 , A61B6/5258 , G06T11/006 , G06T2211/421 , G06T2211/432
摘要： The invention relates to a method for correcting truncation artifacts in a reconstruction method for computed tomography recordings. The projection images are recorded by an x-ray image detector being extended by determining the attenuation of the radiation outside the projection image for pixels. Non-horizontal filter lines are extended by transaxial and axial artificial extension of the x-ray image detector for the purposes of truncation correction. The truncation correction for non-horizontal filter lines being carried out according to a method from at least one of the following groups: truncation correction takes place regardless of the specific location and orientation of the filter lines; truncation correction takes place as a function of the specific position and orientation of the filter lines, with the filter lines themselves being retained; and truncation correction takes place by introducing new modified filter lines, with filtering taking place along offset artificially extended filter lines.
摘要翻译：本发明涉及一种用于计算机断层摄影记录的重建方法中的截断伪影的校正方法。由X射线图像检测器记录投影图像，通过确定像素的投影图像之外的辐射的衰减而被扩展。非水平滤波器线通过X射线图像检测器的横轴和轴向人造延伸来延伸，用于截断校正。对于非水平滤波器线的截断校正根据以下组中的至少一个的方法执行：截断校正发生，而不管滤波器线的具体位置和取向如何; 截断校正作为滤波器线的具体位置和取向的函数发生，滤波器线本身被保持; 并且通过引入新的修改的滤波器线进行截断校正，并且沿着偏移人为扩展的滤波器线进行滤波。

7. 发明申请

US20060123002A1 Operating method for a computer and corresponding devices 失效
标题翻译：计算机及相应设备的操作方法
公开(公告)号：US20060123002A1
公开(公告)日：2006-06-08
申请号：US11294783
申请日：2005-12-06
申请人： Joachim Hornegger , Dietrich Paulus
发明人： Joachim Hornegger , Dietrich Paulus
IPC分类号： G06F7/00 , G06F17/30
CPC分类号： G06T7/38 , G06F19/321 , Y10S707/941
摘要： Two sequences (13, 15) of data sets (14, 16) having at least two dimensions and referring to an object (17) which changes over time are specified to a computer (1). Each data set (14, 16) in each sequence (13, 15) is assigned a measure of time which can be used to determine the temporal relationship of the data sets (14, 16) to the other data sets (14, 16) in the respective sequence (13, 15). The computer (1) compares the first data set (14) in the first sequence (13) with the data sets (16) in the second sequence (15) and automatically determines a first data set (16) from the second sequence (15) corresponding to a first data set (14) from the first sequence (13). With the aid of the corresponding first data sets (14, 16) in the first and second sequences (13, 15) and the measures of time assigned to the data sets (14, 16), the computer then determines, for each of the other data sets (14) in the first sequence, the corresponding data set (16) from the second sequence.
摘要翻译：具有至少两个维度的数据集（14,16）的两个序列（13,15）被指定给计算机（1），并且指向随时间变化的对象（17）。每个序列（13,15）中的每个数据集（14,16）被分配一个时间量度，可以用于确定数据集（14,16）与其他数据集（14,16）的时间关系，在相应的顺序（13,15）中。计算机（1）将第一序列（13）中的第一数据集（14）与第二序列（15）中的数据集（16）进行比较，并且从第二序列（15）自动确定第一数据集（16））对应于来自第一序列（13）的第一数据集（14）。借助于第一和第二序列（13,15）中的对应的第一数据集（14,16）和分配给数据集（14,16）的时间的度量，计算机然后对于每个第一序列中的其他数据集（14），来自第二序列的对应数据集（16）。

8. 发明申请

US20060092160A1 Method for the rapid image processing of medical images 审中-公开
标题翻译：医学图像快速图像处理方法
公开(公告)号：US20060092160A1
公开(公告)日：2006-05-04
申请号：US11254967
申请日：2005-10-20
申请人： Christopher Drexler , Joachim Hornegger , Martin Mack
发明人： Christopher Drexler , Joachim Hornegger , Martin Mack
IPC分类号： G06F15/16
CPC分类号： G06T1/20 , G06T15/005
摘要： The present invention relates to a method for the rapid image processing of medical images, in particular fluoroscopic image recordings using image-modifying image processing algorithms on an image computer. With this method, a first part of the image processing algorithms is executed on a graphics processor of a graphics card and a second remaining part is executed on a master processor of the image computer. This division, for which standard hardware components are to be used, allows the omission of complex special developments of the hardware for the image computer.
摘要翻译：本发明涉及一种用于医学图像的快速图像处理的方法，特别是在图像计算机上使用图像修改图像处理算法的透视图像记录。利用该方法，在图形卡的图形处理器上执行图像处理算法的第一部分，并且在图像计算机的主处理器上执行第二部分。为了使用标准硬件组件，该部门允许省略图像计算机硬件的复杂特殊开发。

9. 发明申请

US20130331687A1 Combined Cardiac and Respiratory Motion Compensation for Atrial Fibrillation Ablation Procedures 有权
标题翻译：心房颤动消融手术联合心脏和呼吸运动补偿
公开(公告)号：US20130331687A1
公开(公告)日：2013-12-12
申请号：US13433817
申请日：2012-03-29
申请人： Rui Liao , Alexander Benjamin Brost , Wen Wu , Terrence Chen , Joachim Hornegger , Martin Willibald Koch , Norbert Strobel , Andreas Wimmer
发明人： Rui Liao , Alexander Benjamin Brost , Wen Wu , Terrence Chen , Joachim Hornegger , Martin Willibald Koch , Norbert Strobel , Andreas Wimmer
IPC分类号： A61B5/06
CPC分类号： A61B5/061 , A61B6/12 , A61B6/487 , A61B6/503 , A61B6/504 , A61B6/5217 , A61B2017/00699 , A61B2017/00703 , A61B2034/2065 , A61B2090/376
摘要： A method for compensating cardiac and respiratory motion in atrial fibrillation ablation procedures includes (a) simultaneously determining a position of a circumferential mapping (CFM) catheter and a coronary sinus (CS) catheter in two consecutive image frames of a series of first 2-D image frames; (b) determining a distance between a virtual electrode on the CS catheter and a center of the CFM catheter for a first image frame of the two consecutive image frames, and for a second image frame of the two consecutive image frames; and (c) if an absolute difference of the distance for the first image frame and the distance for the second image frame is greater than a predetermined threshold, compensating for motion of the CFM catheter in a second 2-D image.
摘要翻译：用于补偿心房颤动消融手术中的心脏和呼吸运动的方法包括（a）同时确定一系列第一2-D的两个连续图像帧中的圆周映射（CFM）导管和冠状窦（CS）导管的位置图像帧; （b）确定所述CS导管上的虚拟电极与所述两个连续图像帧的第一图像帧的所述CFM导管的中心之间的距离，以及所述两个连续图像帧的第二图像帧; 以及（c）如果第一图像帧的距离和第二图像帧的距离的绝对差大于预定阈值，则补偿CFM导管在第二二维图像中的运动。

10. 发明申请

US20120271162A1 Constrained Registration for Motion Compensation in Atrial Fibrillation Ablation Procedures 有权
标题翻译：心房颤动消融手术运动补偿约束注册
公开(公告)号：US20120271162A1
公开(公告)日：2012-10-25
申请号：US13410444
申请日：2012-03-02
申请人： Rui Liao , Alexander Benjamin Brost , Andreas Wimmer , Joachim Hornegger
发明人： Rui Liao , Alexander Benjamin Brost , Andreas Wimmer , Joachim Hornegger
IPC分类号： A61M25/095
CPC分类号： A61B5/7207 , A61B6/12 , A61B6/487 , A61B6/5235 , A61B18/1492 , A61B2018/00357 , A61B2018/00577 , A61B2018/00982 , G06T7/251 , G06T7/285 , G06T2207/10021 , G06T2207/10121 , G06T2207/30021
摘要： A method for model based motion tracking of a catheter during an ablation procedure includes receiving a training series of biplanar fluoroscopic images of a catheter acquired under conditions that will be present during an ablation procedure, segmenting and processing the series of biplanar images to produce a distance transform image for each biplanar image at each acquisition time, minimizing, for each pair of biplanar images at each acquisition time, a cost function of the distance transform image for each pair of biplanar images to yield a translation parameter that provides a best fit for a model of the catheter to each pair of biplanar images at each acquisition time, and calculating an updated catheter model for each acquisition time from said translation parameter.
摘要翻译：一种用于在消融过程期间导管的基于模型的运动跟踪的方法包括接收在消融过程期间将存在的条件下获取的导管的训练系列的双平面荧光透视图像，分割和处理所述一系列双平面图像以产生距离在每个采集时间对每个双平面图像进行变换图像，对于每个采集时间的每对双平面图像，使每对双平面图像的距离变换图像的成本函数最小化，以产生提供最佳拟合的平移参数在每个采集时间对每对双平面图像的导管的模型，以及从所述翻译参数计算每个采集时间的更新的导管模型。

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