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    • 4. 发明授权
    • Dispersion of microparticulate titanium oxide and cosmetics containing the same
    • 微粒氧化钛和含有其的化妆品的分散
    • US08119108B2
    • 2012-02-21
    • US12097330
    • 2006-11-20
    • Akio Nasu
    • Akio Nasu
    • A61Q17/00A61Q17/04A61K8/00A61K8/02A61K8/04A61K8/18A61K33/00
    • A61K8/29A61K8/044A61K8/891A61K8/894A61Q17/04
    • The present invention provides a dispersion of microparticulate titanium oxide that can generate a natural finish feeling, which includes a feeling of transparency, and has good long-term stability and an excellent UV protective effect in both UVA and UVB regions. The present invention is a dispersion of microparticulate titanium oxide characterized in that the microparticulate titanium oxide with the average major axis of 30 to 100 nm and the average minor axis of 8 to 50 nm is dispersed, by maintaining the average size of dispersed particles to be 80 to 110 nm, in a hydrophobic dispersion medium. In the dispersion of microparticulate titanium oxide, the content of silicone oil relative to the total hydrophobic dispersion medium is preferably 10 to 100 weight %. Furthermore, it is preferable that the dispersion of microparticulate titanium oxide contains a biterminally-siliconized polyglycerin as a dispersant. The dispersion of microparticulate titanium oxide can be preferably contained in a cosmetic.
    • 本发明提供了能够产生具有透明感的长时间稳定性以及UVA和UVB区域的优异的紫外线防护效果的微粒化二氧化钛的分散体,能够产生自然的整理感。 本发明是微粒状氧化钛的分散体,其特征在于,通过将分散粒子的平均粒径保持为分散,平均长轴为30〜100nm,平均短轴为8〜50nm的微粒氧化钛为 80-110nm,在疏水分散介质中。 在微粒氧化钛的分散中,硅油相对于总疏水分散介质的含量优选为10〜100重量%。 此外,优选微粒氧化钛的分散体含有作为分散剂的硫酸酯化聚甘油。 微粒氧化钛的分散体可以优选包含在化妆品中。
    • 5. 发明授权
    • Cosmetic sunscreen preparation
    • 化妆品防晒剂
    • US06749838B1
    • 2004-06-15
    • US09807750
    • 2001-04-18
    • Kyoko JoichiKatsuki OgawaKazuhisa OhnoAkio Nasu
    • Kyoko JoichiKatsuki OgawaKazuhisa OhnoAkio Nasu
    • A61K742
    • A61K8/894A61K8/11A61K8/25A61K8/27A61K2800/413A61Q17/04
    • An object of the present invention is to provide a sunscreen cosmetic in which a micro particle zinc oxide is dispersed satisfactorily and which is excellent in the ultraviolet rays protection effect as indicated by SPF and PFA, and also in the finish transparency and the system stability. A sunscreen cosmetic obtained by means of an incorporation of a composite powder of a micro particle zinc oxide having a particle size of 0.1 &mgr;m or less which is coated with a silicic anhydride at a coating rate of 5 to 30 wt % and whose surface is treated with a silicone of 3 to 12 wt %, a dispersing treatment of said composite powder in an oil or water using a media-agitating mill or a high pressure dispersing machine and/or an incorporation of a polyoxyalkylene-modified polysiloxane.
    • 本发明的目的是提供一种令人满意地分散微粒氧化锌的防晒化妆品,其具有如SPF和PFA所示的紫外线防护效果优异,以及最终的透明度和系统稳定性。 一种防晒化妆品,其通过将涂覆有硅酸酐的微粒氧化锌复合粉末以5〜30重量%的涂布速度并且表面被处理而得到, 使用3至12重量%的硅氧烷,使用介质搅拌研磨机或高压分散机将所述复合粉末分散在油或水中,和/或引入聚氧化烯改性的聚硅氧烷。
    • 6. 发明申请
    • Emulsified External Skin Preparations
    • 乳化外用皮肤制剂
    • US20100247458A1
    • 2010-09-30
    • US11996752
    • 2006-07-26
    • Hiroyuki KakokiTakashi OhmoriAkio NasuAkira Ishikubo
    • Hiroyuki KakokiTakashi OhmoriAkio NasuAkira Ishikubo
    • A61K8/34A61Q17/04
    • C07C43/135A61K8/062A61K8/39A61Q1/02A61Q17/04A61Q19/00A61Q19/02
    • The emulsified external skin preparation of the present invention is characterized by comprising a polyglycerol derivative represented by formula (1): wherein, m+2 represents the average polymerization degree of polyglycerol and 1≦m≦4; R1 is a hydrocarbon group having 1 to 4 carbon atoms or a hydrogen atom; AO is an oxyalkylene group having 3 to 4 carbon atoms; and n is the average addition mole number of the oxyalkylene group and 1≦m n≦200. In a water-in-oil type external skin preparation, and especially in that containing a polar oil or a silicone oil, emulsion stability is improved. In an oil-in-water type external skin preparation, feeling in use and emulsion stability are improved. Especially, in an oil-in-water type external skin preparation containing hydrophobized powder, powder dispersion stability is improved as well as feeling in use and emulsion stability.
    • 本发明的乳化外用皮肤制剂的特征在于,含有式(1)表示的聚甘油衍生物:其中,m +2表示聚甘油的平均聚合度,1≦̸ m< 1l; 4; R1为碳原子数为1〜4的烃基或氢原子; AO是具有3〜4个碳原子的氧化烯基; 并且n是氧化烯基的平均加成摩尔数和1≦̸ m n≦̸ 200。 在油包水型外用皮肤制剂中,特别是含有极性油或硅油的乳化稳定性提高。 在水包油型外用皮肤制剂中,使用感和乳液稳定性得到改善。 特别地,在含有疏水化粉末的水包油型外用皮肤制剂中,粉末分散稳定性以及使用感和乳液稳定性均得到改善。
    • 9. 发明申请
    • Oil-in-Water Type Emulsion Cosmetic Composition
    • 油包水型乳液化妆品组合物
    • US20110070173A1
    • 2011-03-24
    • US10540041
    • 2003-12-26
    • Susumu YoshidaTadashi NakamuraKeiko Nakamura-Sole HeirAkira IshikuboAkio Nasu
    • Susumu YoshidaTadashi NakamuraKeiko Nakamura-Sole HeirAkira IshikuboAkio Nasu
    • A61K8/30A61K47/00A61K47/12A61K47/26
    • A61Q19/00A61K8/06A61K8/062A61K8/73A61Q1/02A61Q17/04
    • This object of the invention is to provide an oil-in water emulsion cosmetic composition having fine sense of use and excellent dispersion stability, and does not occur twisting upon drying.In advance, a hydrophobicized powder is dispersed in an oil phase and processed with wet type disperser such as beads mill, dispersing solution is obtained. And then said dispersing solution and a water phase are processed with homomixer, an oil-in water emulsion composition having excellent sense of use and dispersibility of powder after applying to skin can be obtained. The dispersing stability of powder is extremely good by using a particular dispersant and a particular oil component. The dispersion stability of powder is further improved, and the precipitation and creaming of the emulsion particle can be solved by blending thickener having salt tolerance.Sticky feeling is solved by using succinoglycan as a thickener, and twisting is solved by plasticizing said succinoglycan.
    • 本发明的目的是提供一种具有优良的使用感和优异的分散稳定性的油包水乳液化妆品组合物,并且在干燥时不会发生扭曲。 预先将疏水化粉末分散在油相中,用湿式分散机如珠磨机进行处理,得到分散液。 然后用均质混合机处理所述分散溶液和水相,可以获得在施用于皮肤之后具有优异的使用感和粉末分散性的水包油乳液组合物。 通过使用特定的分散剂和特定的油组分,粉末的分散稳定性非常好。 粉末的分散稳定性进一步提高,乳化颗粒的沉淀和乳化可以通过混合具有耐盐性的增稠剂来解决。 通过使用琥珀酰聚糖作为增稠剂来解决粘稠的感觉,并且通过使所述琥珀酰聚糖增塑来解决扭曲。