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1. 发明申请

US20050227227A1 Amplification of HIV-1 gag sequences for detection of sequences associated with drug-resistance mutations 有权
公开(公告)号：US20050227227A1
公开(公告)日：2005-10-13
申请号：US11145272
申请日：2005-06-03
申请人： Yeasing Yang , Steven Brentano , Odile Babola , Nathalie Tran , Guy Vernet
发明人： Yeasing Yang , Steven Brentano , Odile Babola , Nathalie Tran , Guy Vernet
IPC分类号： C07H21/02 , C12Q1/68 , C12Q1/70
CPC分类号： C07H21/02 , C12Q1/703 , H01L2924/014 , H01L2924/14 , Y10S435/974
摘要： Sequences of nucleic acid oligonucleotides for amplifying different portions of gag and pol genes of HIV-1 and for detecting such amplified nucleic acid sequences are disclosed. Methods of amplifying and detecting HIV-1 nucleic acid in a biological sample using the amplification oligonucleotides specific for gag and pol target sequences are disclosed.

2. 发明授权

US07741027B2 Amplification of HIV-1 sequences for detection of sequences associated with drug-resistance mutations 有权
标题翻译：扩增用于检测与耐药性突变相关的序列的HIV-1序列
公开(公告)号：US07741027B2
公开(公告)日：2010-06-22
申请号：US12100350
申请日：2008-04-09
申请人： Yeasing Y. Yang , Steven T. Brentano , Odile Babola , Nathalie Tran , Guy Vernet
发明人： Yeasing Y. Yang , Steven T. Brentano , Odile Babola , Nathalie Tran , Guy Vernet
IPC分类号： C07H21/00 , C12N15/49 , C12Q1/70
CPC分类号： C07H21/02 , C12Q1/703 , H01L2924/014 , H01L2924/14 , Y10S435/974
摘要： Sequences of nucleic acid oligonucleotides for amplifying different portions of gag and pol genes of HIV-1 and for detecting such amplified nucleic acid sequences are disclosed. Methods of amplifying and detecting HIV-1 nucleic acid in a biological sample using the amplification oligonucleotides specific for gag and pol target sequences are disclosed.
摘要翻译：公开了用于扩增HIV-1的gag和pol基因的不同部分的核酸寡核苷酸的序列和用于检测这种扩增的核酸序列的序列。公开了使用特异于gag和pol靶序列的扩增寡核苷酸来扩增和检测生物样品中HIV-1核酸的方法。

3. 发明授权

US07374877B2 Amplification of HIV-1 gag sequences for detection of sequences associated with drug-resistance mutations 有权
标题翻译：扩增用于检测与耐药突变相关的序列的HIV-1 gag序列
公开(公告)号：US07374877B2
公开(公告)日：2008-05-20
申请号：US11145272
申请日：2005-06-03
申请人： Yeasing Y. Yang , Steven T. Brentano , Odile Babola , Nathalie Tran , Guy Vernet
发明人： Yeasing Y. Yang , Steven T. Brentano , Odile Babola , Nathalie Tran , Guy Vernet
IPC分类号： C07H21/00 , C12N15/49
CPC分类号： C07H21/02 , C12Q1/703 , H01L2924/014 , H01L2924/14 , Y10S435/974
摘要： Sequences of nucleic acid oligonucleotides for amplifying different portions of gag and pol genes of HIV-1 and for detecting such amplified nucleic acid sequences are disclosed. Methods of amplifying and detecting HIV-1 nucleic acid in a biological sample using the amplification oligonucleotides specific for gag and pol target sequences are disclosed.
摘要翻译：公开了用于扩增HIV-1的gag和pol基因的不同部分的核酸寡核苷酸的序列和用于检测这种扩增的核酸序列的序列。公开了使用特异于gag和pol靶序列的扩增寡核苷酸来扩增和检测生物样品中HIV-1核酸的方法。

4. 发明申请

US20090047659A1 AMPLIFICATION OF HIV-1 SEQUENCES FOR DETECTION OF SEQUENCES ASSOCIATED WITH DRUG-RESISTANCE MUTATIONS 有权
标题翻译：用于检测与药物耐药突变相关的序列的HIV-1序列的扩增
公开(公告)号：US20090047659A1
公开(公告)日：2009-02-19
申请号：US12100350
申请日：2008-04-09
申请人： Yeasing Y. Yang , Steven T. Brentano , Odile Babola , Nathalie Tran , Guy Vernet
发明人： Yeasing Y. Yang , Steven T. Brentano , Odile Babola , Nathalie Tran , Guy Vernet
IPC分类号： C12Q1/70 , C07H21/04
CPC分类号： C07H21/02 , C12Q1/703 , H01L2924/014 , H01L2924/14 , Y10S435/974
摘要： Sequences of nucleic acid oligonucleotides for amplifying different portions of gag and pol genes of HIV-1 and for detecting such amplified nucleic acid sequences are disclosed. Methods of amplifying and detecting HIV-1 nucleic acid in a biological sample using the amplification oligonucleotides specific for gag and pol target sequences are disclosed.
摘要翻译：公开了用于扩增HIV-1的gag和pol基因的不同部分的核酸寡核苷酸的序列和用于检测这种扩增的核酸序列的序列。公开了使用特异于gag和pol靶序列的扩增寡核苷酸来扩增和检测生物样品中HIV-1核酸的方法。

5. 发明授权

US06946254B2 Amplification of HIV-1 gag sequences for detection of sequences associated with drug-resistance mutations 有权
标题翻译：扩增用于检测与耐药突变相关的序列的HIV-1 gag序列
公开(公告)号：US06946254B2
公开(公告)日：2005-09-20
申请号：US10425975
申请日：2003-04-28
申请人： Yeasing Y. Yang , Steven T. Brentano , Odile Babola , Nathalie Tran , Guy Vernet
发明人： Yeasing Y. Yang , Steven T. Brentano , Odile Babola , Nathalie Tran , Guy Vernet
IPC分类号： C07H21/02 , C12Q1/68 , C12Q1/70
CPC分类号： C07H21/02 , C12Q1/703 , H01L2924/014 , H01L2924/14 , Y10S435/974
摘要： Sequences of nucleic acid oligonucleotides for amplifying different portions of gag and pol genes of HIV-1 and for detecting such amplified nucleic acid sequences are disclosed. Methods of amplifying and detecting HIV-1 nucleic acid in a biological sample using the amplification oligonucleotides specific for gag and pol target sequences are disclosed.
摘要翻译：公开了用于扩增HIV-1的gag和pol基因的不同部分的核酸寡核苷酸的序列和用于检测这种扩增的核酸序列的序列。公开了使用特异于gag和pol靶序列的扩增寡核苷酸来扩增和检测生物样品中HIV-1核酸的方法。

6. 发明授权

US06582920B2 Amplification of HIV-1 RT sequences for detection of sequences associated with drug-resistance mutations 有权
标题翻译：扩增HIV-1 RT序列用于检测与耐药性突变相关的序列
公开(公告)号：US06582920B2
公开(公告)日：2003-06-24
申请号：US09944036
申请日：2001-08-31
申请人： Yeasing Y. Yang , Steven T. Brentano , Odile Babola , Nathalie Tran , Guy Vernet
发明人： Yeasing Y. Yang , Steven T. Brentano , Odile Babola , Nathalie Tran , Guy Vernet
IPC分类号： C12Q168
CPC分类号： C07H21/02 , C12Q1/703 , H01L2924/014 , H01L2924/14 , Y10S435/974
摘要： Sequences of nucleic acid oligonucleotides for amplifying different portions of gag and pol genes of HIV-1 and for detecting such amplified nucleic acid sequences are disclosed. Methods of amplifying and detecting HIV-1 nucleic acid in a biological sample using the amplification oligonucleotides specific for gag and pol target sequences are disclosed.
摘要翻译：公开了用于扩增HIV-1的gag和pol基因的不同部分的核酸寡核苷酸的序列和用于检测这种扩增的核酸序列的序列。公开了使用特异于gag和pol靶序列的扩增寡核苷酸来扩增和检测生物样品中HIV-1核酸的方法。

7. 发明申请

US20050069890A1 Method for the detection and/or identification of the original animal species in animal matter contained in a sample 审中-公开
标题翻译：用于检测和/或鉴定样品中包含的动物物质中的原始动物物种的方法
公开(公告)号：US20050069890A1
公开(公告)日：2005-03-31
申请号：US10500646
申请日：2003-01-10
申请人： Claude Mabilat , Sabine Desvarenne , Odile Babola , Bruno Lacroix , Natalia Bello Pigem
发明人： Claude Mabilat , Sabine Desvarenne , Odile Babola , Bruno Lacroix , Natalia Bello Pigem
IPC分类号： C12N15/09 , C12M1/00 , C12Q1/68 , C12Q1/6876
CPC分类号： C12Q1/6876 , C12Q2600/16
摘要： Disclosed is a method for detecting or identifying the original animal species in a sample likely to contain an ingredient obtained at least from said species. The inventive method is characterized by the following steps: a) a nuclear fraction is obtained from said sample; b) at least one reactant which is specific to the animal species is provided and selected among a group formed by: - the reference sequences SEQ ID numbers 1 to 232, 242 to 261; - the sequences complementing each of the sequences SED ID numbers 1 to 232, 242 to 261, respectively; - the sequences homologous to each of the sequences SEQ ID numbers 1 to 232, 242 to 261 and sequences complementing each of the sequences SED ID numbers 1 to 232, 242 to 261, respectively; c) the nuclear fraction and said reactant are reacted with each other; and d) any signal or information resulting from the specific reaction between said reactant and the nuclear fraction is detected, whereby it can be established if said sample contains said original animal species.
摘要翻译：公开了一种用于检测或鉴定可能含有至少从所述物种获得的成分的样品中的原始动物物种的方法。本发明的方法的特征在于以下步骤：a）从所述样品获得核级分; b）至少一种对动物物种具有特异性的反应物，由选自下组形成的基团： - 参考序列SEQ ID号1至232,242至261; - 分别与每个序列SED ID号1至232,242至261互补的序列; - 与SEQ ID号1至232,242至261中的每一个序列同源的序列和分别与每个序列SED ID编号1至232,242至261互补的序列; c）核部分和所述反应物彼此反应; 并且d）检测由所述反应物和核部分之间的特异性反应产生的任何信号或信息，由此如果所述样品包含所述原始动物物种可以确定。

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