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1. 发明申请

US20060233665A1 Test chip and test chip system 审中-公开
标题翻译：测试芯片和测试芯片系统
公开(公告)号：US20060233665A1
公开(公告)日：2006-10-19
申请号：US11327481
申请日：2006-01-09
申请人： Yasuhiko Sasaki , Osamu Kogi , Hiroshi Kishida , Toru Inaba , Masaomi Uchida
发明人： Yasuhiko Sasaki , Osamu Kogi , Hiroshi Kishida , Toru Inaba , Masaomi Uchida
IPC分类号： B01L3/00
CPC分类号： B01L3/502715 , B01L3/502761 , B01L2200/0668 , B01L2200/143 , B01L2300/0654 , B01L2300/0816 , B01L2300/0867 , B01L2400/0487
摘要： A test chip, which allows a number of solution delivery steps much faster and accurate is provided. The test chip incorporates a sample flow path for containing a sample solution, a reaction flow path for inducing a predetermined reaction with the sample solution, a waste drain path for receiving the used sample, and the washing solution flow paths for containing washing solutions. The reaction flow path contains a plurality of beads having probes of mutually different types fixed thereon. The sample flow path, washing solution flow paths, and sample waste drain path have their respective solution detector units. The solution detector unit detects whether the solution is fed to the path. The detector units adjoiningly provided in the adjacent paths are arranged collinearly.
摘要翻译：提供了一种测试芯片，其允许许多解决方案传送步骤更快速和准确。测试芯片包括用于容纳样品溶液的样品流动路径，用于诱导与样品溶液的预定反应的反应流动路径，用于接收使用的样品的废液排放路径和用于容纳洗涤溶液的洗涤液流路。反应流路包含多个具有固定在其上的相互不同类型的探针的珠。样品流动路径，洗涤液流动路径和样品废物排放路径具有它们各自的溶液检测器单元。溶液检测器单元检测溶液是否被供给到路径。邻接设置在相邻路径中的检测器单元共线布置。

2. 发明申请

US20070243522A1 INSPECTION CHIP FOR BIOLOGICAL MATERIAL 审中-公开
标题翻译：生物材料检验芯片
公开(公告)号：US20070243522A1
公开(公告)日：2007-10-18
申请号：US11679214
申请日：2007-02-27
申请人： Yasuhiko Sasaki , Toru Inaba , Hiroshi Kishida , Osamu Kogi , Masaomi Uchida
发明人： Yasuhiko Sasaki , Toru Inaba , Hiroshi Kishida , Osamu Kogi , Masaomi Uchida
IPC分类号： G01N33/00 , C12M1/00
CPC分类号： B01L3/50273 , B01L2200/027 , B01L2300/0636 , B01L2300/0825 , B01L2300/0877 , B01L2300/14 , B01L2400/0487
摘要： There is provided an inspection chip capable of performing a number of solution feeding processes promptly and accurately. The inspection chip has one continuous flow path comprising a reaction flow path for accommodating a plurality of beads with immobilized probes of types different each other, a first and second solution holding flow path for holding a plurality of solutions each separated by an air gap. The solution is moved from one solution holding flow path to other solution holding flow path via a reaction flow path by utilizing pressure difference.
摘要翻译：提供了能够及时且准确地进行多个溶液供给处理的检查芯片。检查芯片具有一个连续的流动路径，其包括用于容纳具有彼此不同类型的固定化探针的多个珠粒的反应流动路径，用于保持由气隙隔开的多个溶液的第一和第二溶液保持流动路径。通过利用压差将解决方案通过反应流动路径从一个溶液保持流动路径移动到另一溶液保持流动路径。

3. 发明申请

US20080312104A1 BIOLOGICAL MATERIAL PREPARATION CHIP AND PREPARATION CHIP SYSTEM 审中-公开
标题翻译：生物材料制备芯片和制备芯片系统
公开(公告)号：US20080312104A1
公开(公告)日：2008-12-18
申请号：US11763471
申请日：2007-06-15
申请人： Yasuhiko Sasaki , Toru Inaba , Hiroshi Kishida , Masaomi Uchida
发明人： Yasuhiko Sasaki , Toru Inaba , Hiroshi Kishida , Masaomi Uchida
IPC分类号： C40B50/00 , C40B60/14
CPC分类号： B01L3/502746 , B01L2200/0621 , B01L2300/0816 , B01L2300/0867 , B01L2300/0874 , B01L2400/0487 , B01L2400/084
摘要： The present invention is directed to provide a preparation chip system having a simpler configuration and improved reliability while addressing the case where a plurality of reagents have to be fed as in a preparation of extracting DNA from a sample solution. The preparation chip system includes a sample chamber, a dissolving solution chamber, a cleaning solution chamber, an eluting solution chamber, a mixing passage connected to the sample chamber and the dissolving solution chamber and mixing the sample and the dissolving solution with each other, a carrier part connected to the mixing passage, a waste chamber connected to the carrier part via a holding passage, a collection chamber holding the eluting solution passed through the carrier part, and a plurality of resistive materials forming a passage resistor disposed in a first passage connecting the cleaning solution chamber with both the mixing passage and the carrier part. The eluting solution is passed through the carrier part by pressure from a pressure source.
摘要翻译：本发明旨在提供一种制备芯片系统，其具有更简单的结构和改善的可靠性，同时解决了在从样品溶液中提取DNA的制备中必须进料多种试剂的情况。制剂芯片系统包括样品室，溶解溶液室，清洗溶液室，洗脱溶液室，连接到样品室的混合通道和溶解溶液室，并将样品和溶解溶液彼此混合，连接到混合通道的载体部分，经由保持通道连接到载体部分的废物室，保持通过载体部分的洗脱溶液的收集室，以及形成通道电阻器的多个电阻材料，设置在第一通道中，连接所述清洁溶液室具有所述混合通道和所述载体部分。洗脱溶液通过压力源通过载体部分。

4. 发明申请

US20060008821A1 Biomaterial inspection chip 审中-公开
标题翻译：生物材料检验芯片
公开(公告)号：US20060008821A1
公开(公告)日：2006-01-12
申请号：US11094188
申请日：2005-03-31
申请人： Toru Inaba , Yasuhiko Sasaki , Shigenori Togashi , Hiroshi Kishida , Takashi Shimizu
发明人： Toru Inaba , Yasuhiko Sasaki , Shigenori Togashi , Hiroshi Kishida , Takashi Shimizu
IPC分类号： C12Q1/68 , C12M1/34
CPC分类号： B01L9/527 , B01J2219/00466 , B01J2219/00468 , B01J2219/005 , B01J2219/00576 , B01J2219/00657 , B01J2219/00722 , B01J2219/00725 , B01L3/5027 , B01L2200/0647 , B01L2300/0636 , B01L2300/0819 , B01L2300/0883
摘要： Within an inside of a bead chip forming a reactor flow pass therein, rinsing liquid flow passes are also provided in one body. For the purpose of promoting reaction upon a bead array, a turbulence generator or an flow separation stop guide is provided within the reactor flow pass, in which the beads are received. The bead chip is made of a PDMS (Polydimethylsiloxane: (C2H6SiO)n), thereby enabling the reactor flow pass and the rinsing liquid flow passes to be formed freely in the configurations thereof.
摘要翻译：在形成反应器流动通道的珠粒的内部，冲洗液体流动通道也设置在一体中。为了促进珠粒阵列上的反应，在反应器流动通道内提供湍流发生器或流动分离停止引导件，其中容纳珠子。珠芯片由PDMS（聚二甲基硅氧烷：（C 2 H 6 SiO）SiO）N）制成，从而使反应器流过，冲洗液流在其结构中自由形成。

5. 发明申请

US20080247916A1 REACTION APPARATUS AND REACTION CHIP 审中-公开
标题翻译：反应装置和反应芯片
公开(公告)号：US20080247916A1
公开(公告)日：2008-10-09
申请号：US12099181
申请日：2008-04-08
申请人： Toru Inaba , Yasuhiko Sasaki , Hiroshi Kishida
发明人： Toru Inaba , Yasuhiko Sasaki , Hiroshi Kishida
IPC分类号： G05D9/00 , B01J19/00
CPC分类号： B01L3/5027 , B01L7/525 , B01L2200/10 , B01L2300/0816 , B01L2300/0861 , B01L2300/1827 , B01L2300/1883 , B01L2400/0487
摘要： A reaction apparatus is provided with a reaction chip (50) for setting plural temperature regions and including a reaction channel (59) formed over these temperature regions, a pump for supplying a reaction liquid to a reaction channel of the reaction chip (50), a control device for controlling supply of the reaction liquid, and a heater for heating each of the temperature regions of the reaction chip (50) to the preset temperature. The reaction chip (50) is provided with a vacuum shielding layer (62) at the boundaries for separating each of the temperature regions. Accordingly, the reaction apparatus assures uniform and stable reaction within a short period of time.
摘要翻译：反应装置设置有用于设定多个温度区域并包括在这些温度区域上形成的反应通道（59）的反应芯片（50），用于将反应液体供应到反应芯片（50）的反应通道的泵，用于控制反应液供应的控制装置，以及用于将反应芯片（50）的每个温度区域加热到预设温度的加热器。反应芯片（50）在用于分离每个温度区域的边界处设置有真空屏蔽层（62）。因此，反应装置在短时间内保证均匀且稳定的反应。

6. 发明授权

US09557326B2 Sample analyzing device and sample analyzing method 有权
标题翻译：样品分析装置和样品分析方法
公开(公告)号：US09557326B2
公开(公告)日：2017-01-31
申请号：US13702175
申请日：2011-06-07
申请人： Toru Inaba , Shinya Matsuoka , Taku Sakazume , Yoshihiro Yamashita , Masafumi Shimada , Osamu Kogi , Yushi Harada
发明人： Toru Inaba , Shinya Matsuoka , Taku Sakazume , Yoshihiro Yamashita , Masafumi Shimada , Osamu Kogi , Yushi Harada
IPC分类号： G01N33/543 , G01N33/53 , B03C1/033 , B03C1/28 , B03C1/01 , G01N33/574 , G01N35/00
CPC分类号： G01N33/5306 , B03C1/01 , B03C1/033 , B03C1/0332 , B03C1/288 , B03C2201/18 , B03C2201/22 , B03C2201/24 , B03C2201/26 , G01N33/54326 , G01N33/57438 , G01N33/57484 , G01N35/0098
摘要： This invention provides a sample analyzing device and sample analyzing method designed to suppress nonuniform capture of magnetic particles (10) and detect a desired substance with higher accuracy. The sample analyzing device includes a flow channel (15) that conducts thereinto a sample which contains the magnetic particles (10), and magnetic field generating means (12) that generates magnetic fields for capturing the magnetic particles (10) in a magnetic particles capturing region of the flow channel (15); wherein the flow channel has at least one of structural characteristics that a cross-sectional area of the flow channel, at a downstream end of the magnetic particles capturing region, is larger than a cross-sectional area of the flow channel, at an upstream end of the magnetic particles capturing region, and that the magnetic fields generated by the magnetic field generating means (12) have a greater magnitude at a downstream side of the magnetic particles capturing region than at an upstream side thereof.
摘要翻译：本发明提供了一种设计用于抑制磁性颗粒（10）的不均匀捕获并以更高精度检测所需物质的样品分析装置和样品分析方法。样品分析装置包括：导入包含磁性粒子（10）的样品的流路（15）;以及磁场产生装置（12），其产生用于在磁性粒子捕获中捕获磁性粒子（10）的磁场流通道（15）的区域; 其中所述流动通道具有以下结构特征中的至少一个：所述流动通道的在所述磁性粒子捕获区域的下游端处的横截面面积大于所述流动通道的横截面积，在上游端并且由磁场产生装置（12）产生的磁场在磁性颗粒捕获区域的下游侧具有比在其上游侧更大的量值。

7. 发明申请

US20130143234A1 SAMPLE ANALYZING DEVICE AND SAMPLE ANALYZING METHOD 有权
标题翻译：样品分析装置和样品分析方法
公开(公告)号：US20130143234A1
公开(公告)日：2013-06-06
申请号：US13702175
申请日：2011-06-07
申请人： Toru Inaba , Shinya Matsuoka , Taku Sakazume , Yoshihiro Yamashita , Masafumi Shimada , Osamu Kogi , Yushi Harada
发明人： Toru Inaba , Shinya Matsuoka , Taku Sakazume , Yoshihiro Yamashita , Masafumi Shimada , Osamu Kogi , Yushi Harada
IPC分类号： G01N33/53
CPC分类号： G01N33/5306 , B03C1/01 , B03C1/033 , B03C1/0332 , B03C1/288 , B03C2201/18 , B03C2201/22 , B03C2201/24 , B03C2201/26 , G01N33/54326 , G01N33/57438 , G01N33/57484 , G01N35/0098
摘要： This invention provides a sample analyzing device and sample analyzing method designed to suppress nonuniform capture of magnetic particles (10) and detect a desired substance with higher accuracy. The sample analyzing device includes a flow channel (15) that conducts thereinto a sample which contains the magnetic particles (10), and magnetic field generating means (12) that generates magnetic fields for capturing the magnetic particles (10) in a magnetic particles capturing region of the flow channel (15); wherein the flow channel has at least one of structural characteristics that a cross-sectional area of the flow channel, at a downstream end of the magnetic particles capturing region, is larger than a cross-sectional area of the flow channel, at an upstream end of the magnetic particles capturing region, and that the magnetic fields generated by the magnetic field generating means (12) have a greater magnitude at a downstream side of the magnetic particles capturing region than at an upstream side thereof.
摘要翻译：本发明提供了一种设计用于抑制磁性颗粒（10）的不均匀捕获并以更高精度检测所需物质的样品分析装置和样品分析方法。样品分析装置包括：导入包含磁性粒子（10）的样品的流路（15）;以及磁场产生装置（12），其产生用于在磁性粒子捕获中捕获磁性粒子（10）的磁场流通道（15）的区域; 其中所述流动通道具有以下结构特征中的至少一个：所述流动通道的在所述磁性粒子捕获区域的下游端处的横截面面积大于所述流动通道的横截面积，在上游端并且由磁场产生装置（12）产生的磁场在磁性颗粒捕获区域的下游侧具有比在其上游侧更大的量值。

8. 发明授权

US6041052A Call control system for a subscriber transmission device 失效
标题翻译：用户传输设备的呼叫控制系统
公开(公告)号：US6041052A
公开(公告)日：2000-03-21
申请号：US792063
申请日：1997-02-03
申请人： Shoji Miyake , Toru Inaba , Eiji Koda
发明人： Shoji Miyake , Toru Inaba , Eiji Koda
IPC分类号： H04Q3/545 , H04M3/00 , H04M3/22 , H04M3/38 , H04Q11/04 , H04J3/12 , H04M7/06
CPC分类号： H04M3/22 , H04Q11/04 , H04M3/2245 , H04M3/382 , H04Q2213/1301 , H04Q2213/13103 , H04Q2213/13106 , H04Q2213/13204 , H04Q2213/13216 , H04Q2213/13367
摘要： A call control system can cope with a plurality of exchanges that support call control messages issued in accordance with different protocols. The call control system for use in a subscriber transmission device is located along a transmission path between a plurality of subscribers and a plurality of exchanges. The call control system includes call control message terminal sections, each of which is provided for each of the protocols that are supported by the exchanges for terminating a data link for sending and receiving a call control message to and from a corresponding exchange. A call change data processor is provided in the system for detecting a call and a clearance by a subscriber, and for requesting the call control message terminal section, which supports a protocol that corresponds to a protocol of an exchange to which is connected to the subscriber, to transmit the detected contents to the exchange that supports the protocol.
摘要翻译：呼叫控制系统可以处理支持根据不同协议发出的呼叫控制消息的多个交换机。在用户传输设备中使用的呼叫控制系统沿着多个用户和多个交换机之间的传输路径定位。呼叫控制系统包括呼叫控制消息终端部分，每个呼叫控制消息终端部分为交换机支持的每个协议提供，用于终止数据链路，以发送和接收来自对应交换机的呼叫控制消息。在系统中提供呼叫改变数据处理器，用于检测用户的呼叫和间隙，并且用于请求支持与连接到订户的交换机的协议相对应的协议的呼叫控制消息终端部分将检测到的内容发送到支持协议的交换机。

9. 发明授权

US4928163A Semiconductor device 失效
标题翻译：半导体器件
公开(公告)号：US4928163A
公开(公告)日：1990-05-22
申请号：US315196
申请日：1989-02-27
申请人： Toshihiko Yoshida , Toru Inaba
发明人： Toshihiko Yoshida , Toru Inaba
IPC分类号： H01L29/94 , H01L21/265 , H01L21/336 , H01L29/78
CPC分类号： H01L29/6659 , H01L29/7836 , Y10S257/90 , Y10S257/913
摘要： A semiconductor device formed in a semiconductor substrate and having a gate electrode formed on the semiconductor substrate, source and drain regions are formed in said the semiconductor substrate. The source and drain regions are made of a first impurity region doped with impurities of an opposite conductivity type to that of a semiconductor substrate formed at portions adjacent to the edge of the gate electrode, a second impurity region doped with impurities of an opposite conductivity type to that of a semiconductor substrate formed at portions under the first impurity region, and a third impurity region doped with impurities of opposite conductivity type to that of a semiconductor substrate formed at portions spaced apart from the edge of the gate electrode. The impurities of the second impurity region have a diffusion coefficient larger than that of the impurities of the first impurity region. The third impurity region has a higher concentration than that of the first and the second impurity regions and in addition the impurities of the third impurity region have a diffusion coefficient smaller than that of the second impurity region.
摘要翻译：半导体衬底中形成半导体衬底中形成有半导体衬底，源极和漏极区的栅电极的半导体器件。源极和漏极区域由掺杂有与在栅电极的边缘附近形成的部分形成的半导体衬底的导电类型相反的杂质掺杂的第一杂质区域，掺杂有相反导电类型的杂质的第二杂质区域与形成在第一杂质区域下方的部分的半导体衬底的第一杂质区以及掺杂有相反导电类型的杂质的第三杂质区域形成在与栅电极的边缘间隔开的部分的半导体衬底的杂质区域。第二杂质区域的杂质的扩散系数大于第一杂质区域的杂质。第三杂质区域具有比第一和第二杂质区域更高的浓度，另外第三杂质区域的杂质的扩散系数小于第二杂质区域的扩散系数。

10. 发明授权

US09246793B2 Network, network fault recovery method, and node device 有权
标题翻译：网络，网络故障恢复方法和节点设备
公开(公告)号：US09246793B2
公开(公告)日：2016-01-26
申请号：US13424726
申请日：2012-03-20
申请人： Toru Inaba
发明人： Toru Inaba
IPC分类号： G01R31/08 , H04L12/761 , H04L12/707 , H04L12/703 , H04L12/723 , H04L12/26
CPC分类号： H04L45/16 , H04L43/10 , H04L45/22 , H04L45/28 , H04L45/50
摘要： A ring network of a multicast label switch path scheme includes a plurality of nodes connected to form a ring. Further, a signal input to a first one of the nodes is branched to be transmitted in first and second different directions to a second and a third one of the nodes through a first working path and a second working path, respectively, in the ring network, the second one and the third one of the nodes defining end points of the first working path and the second working path, respectively, from the first one of the nodes, and a first backup path is set from the second one of the nodes to the first one of the nodes in the first direction, and a second back up path is set from the third one of the nodes to the first one of the nodes in the second direction.
摘要翻译：组播标签交换路径方案的环形网络包括连接形成环的多个节点。此外，输入到第一个节点的信号被分支以在第一和第二不同方向上分别通过环形网络中的第一工作路径和第二工作路径发送到第二和第三节点，分别从所述第一节点定义所述第一工作路径和所述第二工作路径的端点的所述节点中的第二和第三节点，并且从所述节点中的第二节点设置第一备份路径在第一方向上的第一个节点和第二备份路径被设置为从第三个节点到第二个方向上的第一个节点。

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