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    • 2. 发明申请
    • Benzimidazole-4-Carboxamide Derivatives, Their Preparation Methods, Pharmaceutical Compositions And Their Uses
    • 苯并咪唑-4-甲酰胺衍生物及其制备方法,药物组合物及其用途
    • US20110269766A1
    • 2011-11-03
    • US13143731
    • 2010-01-06
    • Xianjin LuoFei XueZhonglv ZhangNaiyun Xiu
    • Xianjin LuoFei XueZhonglv ZhangNaiyun Xiu
    • A61K31/501
    • A61K31/4184A61K31/4439C07D235/26C07D401/04C07D401/12C07D403/04C07D403/12C07D405/04C07D405/12C07D417/04C07D417/12C07D473/34C07D487/04
    • The present invention relates to the benzimidazole-4-carboxamide derivatives, their preparation methods, pharmaceutical compositions and their uses; wherein X represents monosubstituted or bissubstituted or polysubstitued C1-C14 alkoxy, monosubstituted or bisubstituted or polysubstitued C1-C14 alkyl, monosubstituted or bisubstituted or polysubstitued C2-C14 alkenyl, monosubstituted or bisubstituted or polysubstitued C6-C14 aryl, or monosubstituted or bisubstituted or polysubstitued 5 to 6 membered heterocyclic group, or monosubstituted or bisubstituted or polysubstitued fused ring group containing nitrogen heteroatom; Y represents hydrogen, monosubstituted or bisubstituted or polysubstitued C1-C16 alkyl, monosubstituted or bisubstituted or polysubstitued C6-C12 aryl, or monosubstituted or bisubstituted or polysubstitued 5 to 6 membered heterocyclic group, or monosubstituted or bisubstituted or polysubstitued fused ring group containing nitrogen heteroatom. The derivatives of the present invention have the functions of antiviral medicine.
    • 本发明涉及苯并咪唑-4-甲酰胺衍生物,其制备方法,药物组合物及其用途; 其中X表示单取代或双取代或多取代的C 1 -C 14烷氧基,单取代或双取代或多取代的C 1 -C 14烷基,单取代或双取代或多取代的C 2 -C 14烯基,单取代或双取代或多取代的C 6 -C 14芳基,或单取代或双取代或多取代的5 至6元杂环基团,或含有氮杂原子的单取代或双取代或多取代的稠环基团; Y代表氢,单取代或双取代或多取代的C1-C16烷基,单取代或双取代或多取代的C6-C12芳基,或单取代或双取代或多取代的5至6元杂环基团,或含有氮杂原子的单取代或双取代或多取代的稠环基团。 本发明的衍生物具有抗病毒药物的功能。