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1. 发明授权

US07651695B2 Medicated stents for the treatment of vascular disease 失效
标题翻译：用于治疗血管疾病的药物支架
公开(公告)号：US07651695B2
公开(公告)日：2010-01-26
申请号：US09860384
申请日：2001-05-18
申请人： Wouter E. Roorda , Vinayak D. Bhat , Steven L. Mouw , Syed F. A. Hossainy , Steven Z. Wu , Deborra Sanders Millare
发明人： Wouter E. Roorda , Vinayak D. Bhat , Steven L. Mouw , Syed F. A. Hossainy , Steven Z. Wu , Deborra Sanders Millare
IPC分类号： A61F2/00 , A61F2/06
CPC分类号： A61L31/16 , A61L31/10 , A61L2300/416 , A61L2300/606 , C08L29/04
摘要： The invention provides bioactive compositions and methods of delivery for ameliorating a vascular diseased state, particularly for the management of stenosis or restenosis following a vascular trauma or disease.
摘要翻译：本发明提供用于改善血管疾病状态的生物活性组合物和递送方法，特别是用于在血管创伤或疾病之后管理狭窄或再狭窄。

2. 发明授权

US06447521B1 Foamed inner member cover stent retention and method of use 失效
标题翻译：发泡内部构件覆盖支架保留和使用方法
公开(公告)号：US06447521B1
公开(公告)日：2002-09-10
申请号：US09662551
申请日：2000-09-15
申请人： Steven L. Mouw , Murthy V. Simhambhatla , Chicheng Wang
发明人： Steven L. Mouw , Murthy V. Simhambhatla , Chicheng Wang
IPC分类号： A61F1100
CPC分类号： A61F2/958 , A61F2002/9583
摘要： A catheter system for removably securing a stent which generally includes an inner tubular member and an outer tubular member with an expandable member disposed about the inner tubular member. A foamed cover is disposed between the expandable member and the inner tubular member. An expandable stent is crimped onto the expandable member and is retained in place by compressing the foamed cover. Used with a stent delivery system, the catheter system is inserted into a body lumen such as an artery. The stent is secured in place while advancing the system through tortuous body lumen passages. The stent is advanced to the desired location in the body lumen and implanted by inflating the expandable member and thereby expanding the stent into the body lumen. The stent is released from the system by deflating the expandable member and withdrawing the catheter system from the body.
摘要翻译：一种用于可拆卸地固定支架的导管系统，其通常包括内部管状构件和具有围绕内部管状构件设置的可扩张构件的外部管状构件。泡沫盖布置在可膨胀构件和内管状构件之间。可扩张支架被卷曲到可膨胀构件上并通过压缩发泡盖保持在适当的位置。与支架输送系统一起使用时，将导管系统插入诸如动脉的体腔内。支架固定在适当的位置，同时使系统通过曲折的体腔通道。支架前进到体腔内的所需位置，并且通过使可膨胀构件膨胀并从而将支架扩张到体腔中而植入。支架通过使可膨胀构件放气并将导管系统从身体上取出而从系统释放。

3. 发明授权

US06746469B2 Balloon actuated apparatus having multiple embolic filters, and method of use 有权
标题翻译：具有多个栓塞过滤器的气球致动装置及其使用方法
公开(公告)号：US06746469B2
公开(公告)日：2004-06-08
申请号：US09845788
申请日：2001-04-30
申请人： Steven L. Mouw
发明人： Steven L. Mouw
IPC分类号： A61M2900
CPC分类号： A61F2/958 , A61F2/013 , A61F2/24 , A61F2002/018 , A61F2230/0006 , A61F2230/0067
摘要： An apparatus having multiple filters for capturing embolic material released from a lesion in an occluded body vessel being treated with an interventional procedure. The filters are placed downstream from the lesion, and the porosity of the filters decreases for each succeeding filter downstream from the lesion. Before encountering the filters, the embolic material passes a unidirectional barrier acting as a one-way valve to prevent backflow. The unidirectional barrier and filters are positioned along a plurality of arms. The arms may be fabricated from a memory metal, and the memory position of the plurality of arms is a collapsed position surrounding a common longitudinal axis. The apparatus includes an expansion member, such as a balloon, which inflates to move the plurality of arms radially outward to deploy the filters. Embolic material passes through the unidirectional barrier and is trapped between the layers of filters. When the balloon is deflated, the plurality of arms return to the memory position, collapse the unidirectional barrier and the filters, and embolic material remains trapped between the layers of filters.
摘要翻译：一种具有多个过滤器的装置，用于捕获通过介入过程处理的封闭体血管中的病变中释放的栓塞物质。过滤器被放置在病变的下游，并且对于病灶下游的每个随后的过滤器，滤器的孔隙率降低。在遇到过滤器之前，栓塞物通过作为单向阀的单向屏障以防止回流。单向障碍物和过滤器沿着多个臂定位。臂可以由记忆金属制成，并且多个臂的存储位置是围绕公共纵轴的折叠位置。该装置包括膨胀构件，例如气囊，其膨胀以使多个臂径向向外移动以展开过滤器。栓塞材料通过单向障碍物并被捕获在过滤器层之间。当气囊收缩时，多个臂返回到存储器位置，使单向障碍物和过滤器塌陷，并且栓塞物质仍然被捕获在过滤器层之间。

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