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1. 发明授权

US08257386B2 Surgical instrument 有权
标题翻译：手术器械
公开(公告)号：US08257386B2
公开(公告)日：2012-09-04
申请号：US11900417
申请日：2007-09-11
申请人： Woojin Lee , Andres Chamorro , Richard Ross , Marvin A. Guiles , Eileen M. Heneberry , James C. Hollenbeck
发明人： Woojin Lee , Andres Chamorro , Richard Ross , Marvin A. Guiles , Eileen M. Heneberry , James C. Hollenbeck
IPC分类号： A61B17/00
CPC分类号： A61B17/2909 , A61B50/30 , A61B2017/0046 , A61B2017/292 , A61B2017/2929
摘要： A medical instrument having a proximal control handle and a distal tool that are intercoupled by an elongated instrument shaft that is meant to pass internally of an anatomic body, proximal and distal movable members that respectively intercouple the proximal control handle and the distal tool with the instrument shaft, cable control means disposed between the movable members, an actuation member at the handle for controlling the distal tool through the movable members, and a coupler for selectively engaging or disengaging separable cable segments of the actuation member.
摘要翻译：一种具有近端控制手柄和远端工具的医疗器具，所述近端控制手柄和远端工具由细长的仪器轴相互联合，所述细长的仪器轴旨在通过解剖体内部的近端和远端可移动构件的内部，所述近端和远端可移动构件分别使所述近端控制手柄和所述远端工具与所述仪器轴，设置在可动构件之间的电缆控制装置，在手柄处的致动构件，用于通过可移动构件控制远端工具;以及联接器，用于选择性地接合或脱离致动构件的可分离的电缆段。

2. 发明申请

US20090069842A1 Surgical instrument 有权
标题翻译：手术器械
公开(公告)号：US20090069842A1
公开(公告)日：2009-03-12
申请号：US11900417
申请日：2007-09-11
申请人： Woojin Lee , Andres Chamorro , Richard Ross , Marvin A. Guiles , Eileen M. Heneberry , James C. Hollenbeck
发明人： Woojin Lee , Andres Chamorro , Richard Ross , Marvin A. Guiles , Eileen M. Heneberry , James C. Hollenbeck
IPC分类号： A61B17/00
CPC分类号： A61B17/2909 , A61B50/30 , A61B2017/0046 , A61B2017/292 , A61B2017/2929
摘要： A medical instrument having a proximal control handle and a distal tool that are intercoupled by an elongated instrument shaft that is meant to pass internally of an anatomic body, proximal and distal movable members that respectively intercouple the proximal control handle and the distal tool with the instrument shaft, cable control means disposed between the movable members, an actuation member at the handle for controlling the distal tool through the movable members, and a coupler for selectively engaging or disengaging separable cable segments of the actuation member.
摘要翻译：一种具有近端控制手柄和远端工具的医疗器具，所述近端控制手柄和远端工具由细长的仪器轴彼此相互配合，所述远端工具意在通过解剖体内部通过的近端和远端可移动部件，所述近端和远端可移动部件分别使所述近端控制手柄和所述远端工具与所述仪器轴，设置在可动构件之间的电缆控制装置，在手柄处的致动构件，用于通过可移动构件控制远端工具;以及联接器，用于选择性地接合或脱离致动构件的可分离的电缆段。

3. 发明申请

US20120303006A1 SURGICAL INSTRUMENT 审中-公开
标题翻译：手术器械
公开(公告)号：US20120303006A1
公开(公告)日：2012-11-29
申请号：US13570317
申请日：2012-08-09
申请人： Woojin Lee , Andres Chamorro , Richard Ross , Marvin A. Guiles , Eileen M. Heneberry , James C. Hollenbeck
发明人： Woojin Lee , Andres Chamorro , Richard Ross , Marvin A. Guiles , Eileen M. Heneberry , James C. Hollenbeck
IPC分类号： A61B17/00
CPC分类号： A61B17/2909 , A61B50/30 , A61B2017/0046 , A61B2017/292 , A61B2017/2929
摘要： A medical instrument having a proximal control handle and a distal tool that are intercoupled by an elongated instrument shaft that is meant to pass internally of an anatomic body, proximal and distal movable members that respectively intercouple the proximal control handle and the distal tool with the instrument shaft, cable control means disposed between the movable members, an actuation member at the handle for controlling the distal tool through the movable members, and a coupler for selectively engaging or disengaging separable cable segments of the actuation member.
摘要翻译：一种具有近端控制手柄和远端工具的医疗器具，所述近端控制手柄和远端工具由细长的仪器轴相互联合，所述细长的仪器轴旨在通过解剖体内部的近端和远端的可移动部件，所述近端和远端可移动部件分别使所述近端控制手柄和远端工具与仪器轴，设置在可动构件之间的电缆控制装置，在手柄处的致动构件，用于通过可移动构件控制远端工具;以及联接器，用于选择性地接合或脱离致动构件的可分离的电缆段。

4. 发明申请

US20090171147A1 Surgical instrument 审中-公开
标题翻译：手术器械
公开(公告)号：US20090171147A1
公开(公告)日：2009-07-02
申请号：US12006278
申请日：2007-12-31
申请人： Woojin Lee , Andres Chamorro , James C. Hollenbeck , Richard Ross
发明人： Woojin Lee , Andres Chamorro , James C. Hollenbeck , Richard Ross
IPC分类号： A61B1/018 , A61B1/00
CPC分类号： A61B17/2909 , A61B17/29 , A61B17/32002 , A61B18/1445 , A61B18/1482 , A61B2017/003 , A61B2017/00309 , A61B2017/00327 , A61B2017/0046 , A61B2017/00464 , A61B2017/00477 , A61B2017/291 , A61B2017/2919 , A61B2017/292 , A61B2017/2929 , A61B2017/2931 , A61B2017/2946 , A61B2018/00595
摘要： A medical instrument having a proximal control handle and a distal tool that are intercoupled by an elongated instrument shaft that is meant to pass internally of an anatomic body, proximal and distal movable members that respectively intercouple the proximal control handle and the distal tool with the instrument shaft, cable control means disposed between the movable members, an actuation member at the handle for controlling the distal tool through the movable members, and a coupler for selectively engaging or disengaging the shaft portion of the instrument from the handle portion. The handle has a distal receiver portion, and a shaft connector on said proximal motion member is selectively engageable with and releaseable from the receiver portion.
摘要翻译：一种具有近端控制手柄和远端工具的医疗器具，所述近端控制手柄和远端工具由细长的仪器轴相互联合，所述细长的仪器轴旨在通过解剖体内部的近端和远端可移动构件的内部，所述近端和远端可移动构件分别使所述近端控制手柄和所述远端工具与所述仪器轴，设置在可动构件之间的电缆控制装置，在手柄处的致动构件，用于通过可移动构件控制远端工具;以及联接器，用于选择性地将器械的轴部分与手柄部分接合或分离。手柄具有远端接收器部分，并且所述近端运动构件上的轴连接器可选择性地与接收器部分接合并从接收器部分释放。

5. 发明授权

US08709037B2 Surgical instrument 有权
标题翻译：手术器械
公开(公告)号：US08709037B2
公开(公告)日：2014-04-29
申请号：US12798552
申请日：2010-04-06
申请人： Woojin Lee , Andres Chamorro , Richard Ross , Richard C. Fortier , Jeffrey C. Cerier
发明人： Woojin Lee , Andres Chamorro , Richard Ross , Richard C. Fortier , Jeffrey C. Cerier
IPC分类号： A61B17/00
CPC分类号： A61B17/29 , A61B2017/003 , A61B2017/2905 , A61B2017/291 , A61B2017/292
摘要： The surgical instrument includes a distal tool, an elongated shaft that supports the distal tool, and a proximal handle or control member, where the tool and the handle are coupled to the respective distal and proximal ends of the elongated shaft via distal and proximal bendable motion members. Actuation means extends between said distal and proximal members whereby any deflection of said control handle with respect to said elongated instrument shaft causes a corresponding bending of said distal motion member for control of said working member. The proximal bendable member comprises a ball and socket assembly supported between the handle and instrument shaft and constructed and arranged for three dimensional motion.
摘要翻译：手术器械包括远端工具，支撑远端工具的细长轴和近侧手柄或控制构件，其中工具和手柄通过远端和近端可弯曲运动联接到细长轴的相应远端和近端会员致动装置在所述远端和近端构件之间延伸，从而所述控制手柄相对于所述细长仪器轴的任何偏转导致所述远端运动构件的相应弯曲以控制所述工作构件。近端可弯曲构件包括支撑在手柄和仪器轴之间的球窝组件，并被构造和布置用于三维运动。

6. 发明申请

US20100228235A1 Surgical instrument 有权
标题翻译：手术器械
公开(公告)号：US20100228235A1
公开(公告)日：2010-09-09
申请号：US12798552
申请日：2010-04-06
申请人： Woojin Lee , Andres Chamorro , Richard Ross
发明人： Woojin Lee , Andres Chamorro , Richard Ross
IPC分类号： A61B17/00
CPC分类号： A61B17/29 , A61B2017/003 , A61B2017/2905 , A61B2017/291 , A61B2017/292
摘要： The surgical instrument includes a distal tool, an elongated shaft that supports the distal tool, and a proximal handle or control member, where the tool and the handle are coupled to the respective distal and proximal ends of the elongated shaft via distal and proximal bendable motion members. Actuation means extends between said distal and proximal members whereby any deflection of said control handle with respect to said elongated instrument shaft causes a corresponding bending of said distal motion member for control of said working member. The proximal bendable member comprises a ball and socket assembly supported between the handle and instrument shaft and constructed and arranged for three dimensional motion.
摘要翻译：手术器械包括远端工具，支撑远端工具的细长轴和近侧手柄或控制构件，其中工具和手柄通过远端和近端可弯曲运动联接到细长轴的相应远端和近端会员致动装置在所述远端和近端构件之间延伸，从而所述控制手柄相对于所述细长仪器轴的任何偏转导致所述远端运动构件的相应弯曲以控制所述工作构件。近端可弯曲构件包括支撑在手柄和仪器轴之间的球窝组件，并被构造和布置用于三维运动。

7. 发明授权

US07708758B2 Surgical instrument 有权
公开(公告)号：US07708758B2
公开(公告)日：2010-05-04
申请号：US11605694
申请日：2006-11-28
申请人： Woojin Lee , Andres Chamorro , Richard Ross
发明人： Woojin Lee , Andres Chamorro , Richard Ross
IPC分类号： A61B17/00
CPC分类号： A61B17/29 , A61B2017/003 , A61B2017/2905 , A61B2017/291 , A61B2017/292
摘要： The surgical instrument includes a distal tool, an elongated shaft that supports the distal tool, and a proximal handle or control member, where the tool and the handle are coupled to the respective distal and proximal ends of the elongated shaft via distal and proximal bendable motion members. Actuation means extends between said distal and proximal members whereby any deflection of said control handle with respect to said elongated instrument shaft causes a corresponding bending of said distal motion member for control of said working member. The proximal bendable member comprises a ball and socket assembly supported between the handle and instrument shaft and constructed and arranged for three dimensional motion.

8. 发明申请

US20080046000A1 Surgical instrument 有权
标题翻译：手术器械
公开(公告)号：US20080046000A1
公开(公告)日：2008-02-21
申请号：US11605694
申请日：2006-11-28
申请人： Woojin Lee , Andres Chamorro , Richard Ross
发明人： Woojin Lee , Andres Chamorro , Richard Ross
IPC分类号： A61B17/00
CPC分类号： A61B17/29 , A61B2017/003 , A61B2017/2905 , A61B2017/291 , A61B2017/292
摘要： The surgical instrument includes a distal tool, an elongated shaft that supports the distal tool, and a proximal handle or control member, where the tool and the handle are coupled to the respective distal and proximal ends of the elongated shaft via distal and proximal bendable motion members. Actuation means extends between said distal and proximal members whereby any deflection of said control handle with respect to said elongated instrument shaft causes a corresponding bending of said distal motion member for control of said working member. The proximal bendable member comprises a ball and socket assembly supported between the handle and instrument shaft and constructed and arranged for three dimensional motion.
摘要翻译：手术器械包括远端工具，支撑远端工具的细长轴和近侧手柄或控制构件，其中工具和手柄通过远端和近端可弯曲运动联接到细长轴的相应远端和近端会员致动装置在所述远端和近端构件之间延伸，从而所述控制手柄相对于所述细长仪器轴的任何偏转导致所述远端运动构件的相应弯曲以控制所述工作构件。近端可弯曲构件包括支撑在手柄和仪器轴之间的球窝组件，并被构造和布置用于三维运动。

9. 发明申请

US20140336117A1 MODIFIED RECEPTOR FUSION PROTEINS 有权
标题翻译：改良受体融合蛋白
公开(公告)号：US20140336117A1
公开(公告)日：2014-11-13
申请号：US14004684
申请日：2012-03-14
申请人： Peter Artymiuk , Ian Wilkinson , Richard Ross
发明人： Peter Artymiuk , Ian Wilkinson , Richard Ross
IPC分类号： C07K14/61 , C07K14/72
CPC分类号： C07K14/61 , A61K38/00 , C07K14/71 , C07K14/72 , C07K2319/00 , C07K2319/02 , C07K2319/21
摘要： We disclose growth hormone fusion proteins that have increased in vivo stability and activity; nucleic acid molecules encoding said proteins and methods of treatment of growth hormone related diseases that would benefit from growth hormone agonists or antagonists.
摘要翻译：我们公开了具有增加的体内稳定性和活性的生长激素融合蛋白; 编码所述蛋白质的核酸分子和治疗生长激素相关疾病的方法，其将受益于生长激素激动剂或拮抗剂。

10. 发明申请

US20110182848A1 GRANULOCYTE COLONY STIMULATING FACTOR 审中-公开
标题翻译： GRANULOCYTE COLONY刺激因子
公开(公告)号：US20110182848A1
公开(公告)日：2011-07-28
申请号：US12671987
申请日：2008-07-31
申请人： Peter Artymiuk , Richard Ross , Jon Sayers
发明人： Peter Artymiuk , Richard Ross , Jon Sayers
IPC分类号： A61K38/19 , C07K14/535 , C07H21/04 , C12N15/63 , C12N5/16 , A61P37/04 , C12N1/00 , C12N5/14
CPC分类号： C07K14/535 , C07K14/715 , C07K2319/00
摘要： We disclose granulocyte colony stimulating factor fusion polypeptides; nucleic acid molecules encoding said polypeptides and methods of treatment that use said proteins.
摘要翻译：我们公开了粒细胞集落刺激因子融合多肽; 编码所述多肽的核酸分子和使用所述蛋白质的治疗方法。

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