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1. 发明授权

US06575927B1 System and method for determining blood flow rate in a vessel 失效
标题翻译：用于确定血管中血流速度的系统和方法
公开(公告)号：US06575927B1
公开(公告)日：2003-06-10
申请号：US09310673
申请日：1999-05-12
申请人： William F. Weitzel , Jonathan M. Rubin , Joseph M. Messana
发明人： William F. Weitzel , Jonathan M. Rubin , Joseph M. Messana
IPC分类号： A61M500
CPC分类号： A61M1/3663 , A61M1/3658
摘要： A system and method are provided for determining the performance of a vessel, such as a hemodialysis access, which communicates blood between two locations of a patient. A conduit, such as an external dialysis circuit or an intravascular catheter, is provided in fluid communication with the vessel, and has a diversion point for diverting blood from the vessel into the conduit. The system further includes means for determining a flow rate of the diverted blood through the conduit. A first sensor in communication with the vessel generates at least one signal that is a function of a blood flow rate in the vessel downstream from the diversion point, wherein the downstream flow rate depends on the determined conduit flow rate and the performance of the vessel can be determined based on the signal. In addition, a processor can be provided in communication with the first sensor for determining a flow rate in the vessel upstream from the diversion point from the signal and the conduit flow rate. In a preferred embodiment, the first sensor is an ultrasonic sensor, and the at least one signal represents a time-averaged mean Doppler velocity of blood flow. Still further, additional sensors may be employed to provide a measure of the upstream flow rate as well as the conduit flow rate.
摘要翻译：提供了一种系统和方法，用于确定在患者的两个位置之间传送血液的血管的血液透析进入的血管的性能。提供与容器流体连通的导管，例如外部透析回路或血管内导管，并具有用于将血液从血管转移到导管中的转移点。该系统还包括用于确定通过导管的转运血液的流量的装置。与容器连通的第一传感器产生至少一个信号，该信号是从转向点下游的血管中的血液流速的函数，其中下游流速取决于确定的导管流速和容器的性能根据信号确定。此外，可以提供与第一传感器通信的处理器，用于从信号和导管流量确定从转向点上游的容器中的流量。在优选实施例中，第一传感器是超声波传感器，并且所述至少一个信号表示血流的时间平均平均多普勒速度。此外，可以使用附加的传感器来提供上游流量以及导管流量的量度。

2. 发明授权

US06709414B2 System for determining blood flow rate in a vessel using diverted flow measurements 失效
标题翻译：用于使用转向流量测量来确定血管中血流速度的系统
公开(公告)号：US06709414B2
公开(公告)日：2004-03-23
申请号：US10372470
申请日：2003-02-21
申请人： William F. Weitzel , Jonathan M. Rubin , Joseph M. Messana
发明人： William F. Weitzel , Jonathan M. Rubin , Joseph M. Messana
IPC分类号： A61M3700
CPC分类号： A61M1/3663 , A61M1/3658
摘要： A system and method are provided for determining the performance of a vessel, such as a hemodialysis access, which communicates blood between two locations of a patient. A conduit, such as an external dialysis circuit or an intravascular catheter, is provided in fluid communication with the vessel, and has a diversion point for diverting blood from the vessel into the conduit. The system further includes means for determining a flow rate of the diverted blood through the conduit. A first sensor in communication with the vessel generates at least one signal that is a function of a blood flow rate in the vessel downstream from the diversion point, wherein the downstream flow rate depends on the determined conduit flow rate and the performance of the vessel can be determined based on the signal. In addition, a processor can be provided in communication with the first sensor for determining a flow rate in the vessel upstream from the diversion point from the signal and the conduit flow rate. In a preferred embodiment, the first sensor is an ultrasonic sensor, and the at least one signal represents a time-averaged mean Doppler velocity of blood flow. Still further, additional sensors may be employed to provide a measure of the upstream flow rate as well as the conduit flow rate.
摘要翻译：提供了一种系统和方法，用于确定在患者的两个位置之间传送血液的血管的血液透析进入的血管的性能。提供与容器流体连通的导管，例如外部透析回路或血管内导管，并具有用于将血液从血管转移到导管中的转移点。该系统还包括用于确定通过导管的转运血液的流量的装置。与容器连通的第一传感器产生至少一个信号，该信号是从转向点下游的血管中的血液流速的函数，其中下游流速取决于确定的导管流速和容器的性能根据信号确定。此外，可以提供与第一传感器通信的处理器，用于从信号和导管流量确定从转向点上游的容器中的流量。在优选实施例中，第一传感器是超声波传感器，并且所述至少一个信号表示血流的时间平均平均多普勒速度。此外，可以使用附加的传感器来提供上游流量以及导管流量的量度。

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