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1. 发明授权

US6110103A Disposable endoscope sheath 失效
标题翻译：一次性内镜套
公开(公告)号：US6110103A
公开(公告)日：2000-08-29
申请号：US93619
申请日：1998-06-09
申请人： William Donofrio
发明人： William Donofrio
IPC分类号： A61B1/00 , A61B1/12 , A61B1/015
CPC分类号： A61B1/00142 , A61B1/126
摘要： The disposable endoscope sheath includes a low-profile sleeve member that can accommodate a variety of different endoscope lengths that are longer than the sleeve member. In several embodiments of the invention, the sleeve member includes irrigation channels that do not communicate with an endoscope receiving space. In other embodiments of the invention, irrigation fluid passes through the endoscope receiving space of the sleeve member. In all embodiments of the invention, irrigation fluid that is expelled from the sleeve member can flush surgical debris away from the viewing end of the endoscope. The sleeve member has a generally low profile and does not require continuous suction to halt the expulsion of irrigation fluid from the sheath when the irrigation function is not being used. A brief reverse suction can be used to remove a residual drop of cleaning solution from the viewing end of the sheath.
摘要翻译：一次性内窥镜套管包括可以适应比套筒构件更长的各种不同内窥镜长度的低轮廓套筒构件。在本发明的若干实施例中，套筒构件包括不与内窥镜接收空间连通的冲洗通道。在本发明的其它实施例中，冲洗流体穿过套筒构件的内窥镜容纳空间。在本发明的所有实施例中，从套筒构件排出的冲洗流体可以将内窥镜的观察端的外科手术碎片冲洗掉。当不使用冲洗功能时，套筒构件具有通常低的轮廓并且不需要连续的抽吸以停止冲洗流体从护套的排出。可以使用简单的反向抽吸来从护套的观察端去除残留的清洁溶液滴。

2. 发明授权

US5989183A Disposable endoscope sheath 失效
标题翻译：一次性内镜套
公开(公告)号：US5989183A
公开(公告)日：1999-11-23
申请号：US129180
申请日：1998-06-05
申请人： Dennis Reisdorf , William Donofrio
发明人： Dennis Reisdorf , William Donofrio
IPC分类号： A61B1/00 , A61B1/12
CPC分类号： A61B1/00091 , A61B1/00135 , A61B1/00142 , A61B1/12
摘要： The disposable endoscope sheath includes a low-profile sleeve member that cooperates with the endoscope shaft to establish a relatively narrow irrigation space between the sleeve member and the endoscope shaft. The sleeve member is intentionally shorter than the endoscope shaft to accommodate a variety of different endoscope lengths that are longer than the sleeve. In various embodiments of the invention the sleeve member can be positioned to establish a predetermined distal gap between the terminal end of the sleeve member and the viewing end of the endoscope shaft, to establish a flush alignment between the respective ends, or to have the endoscope shaft project slightly beyond the terminal end of the sleeve member. Irrigation fluid can thus flow across the viewing end of the endoscope flushing away surgical debris from the viewing end. The sleeve member can be a rigid or flexible structure. The size of the irrigation space is sized to permit retention of irrigation solution in the irrigation space when irrigation fluid is no longer being directed into the irrigation space.
摘要翻译：一次性内窥镜护套包括与内窥镜轴配合的低轮廓套筒构件，以在套筒构件和内窥镜轴之间建立相对较窄的冲洗空间。套筒构件有意地比内窥镜轴短，以适应比套筒更长的各种不同的内窥镜长度。在本发明的各种实施例中，套筒构件可以被定位成在套筒构件的终端和内窥镜轴的观察端之间建立预定的远端间隙，以在各个端部之间建立平齐的对准，或者使内窥镜轴项目稍微超过套筒构件的终端。因此，灌注流体可以流过内窥镜的观察端，从观察端冲洗手术碎片。套筒构件可以是刚性或柔性结构。当灌溉流体不再被引导到灌溉空间中时，灌溉空间的大小被确定为允许将灌溉溶液留在灌溉空间中。

3. 发明申请

US20080015620A1 METHOD FOR DIFFERENTIATING BETWEEN BURDENED AND CRACKED ULTRASONICALLY TUNED BLADES 审中-公开
标题翻译：用于分辨膨胀和破裂的超声波调谐叶片的方法
公开(公告)号：US20080015620A1
公开(公告)日：2008-01-17
申请号：US11776606
申请日：2007-07-12
申请人： Allan Friedman , William Donofrio
发明人： Allan Friedman , William Donofrio
IPC分类号： A61B17/32 , G01N29/00
CPC分类号： A61B17/320068 , A61B2017/00022 , A61B2017/00026 , A61B2017/00106 , A61B2017/00725 , A61B2017/320069 , A61B2017/320071 , A61B2017/320075 , G01N29/09 , G01N29/4427 , G01N2291/018 , G01N2291/02881 , G01N2291/101 , G01N2291/2698
摘要： A method for differentiating between ultrasonically tuned blades which are broken or cracked, and blades which are gunked by evaluating measured impedance differences. The method is performed irrespective of the age of the hand piece/blade, the temperature or specific type of hand piece or blade, and is not affected by self healing effects of slightly cracked blades. Moreover, the method facilitates the quantifiable determination of the amount of gunk on the blade. Absolute impedance measurements of the transducer or blade are unnecessary. Instead, only relative impedance measurements are required, which greatly simplifies the measuring criteria. This provides a way to measure the amount of gunk accumulation, and thereby a way to calculate/estimate the amount of heat generated at the sheath, as well as a way to calculate/estimate the amounts of degradation to the load curve of the ultrasonic system.
摘要翻译：用于区分破碎或破裂的超声波调谐叶片的方法以及通过评估测量的阻抗差异而被枪击的叶片。无论手部/刀片的年龄，手段或刀片的温度或具体类型如何，均执行该方法，并且不受稍微破裂的刀片的自愈效果的影响。此外，该方法有助于可量化确定叶片上的块的量。换能器或刀片的绝对阻抗测量是不必要的。相反，只需要相对阻抗测量，这大大简化了测量标准。这提供了一种测量组合积累量的方法，从而计算/估计在护套处产生的热量的方法，以及计算/估计超声波系统的负载曲线的劣化量的方法。

4. 发明申请

US20070238992A1 Implantable sensor 审中-公开
标题翻译：植入式传感器
公开(公告)号：US20070238992A1
公开(公告)日：2007-10-11
申请号：US11344667
申请日：2006-02-01
申请人： William Donofrio , Jeffrey Nycz , Can Cinbis , Matthew Morrison , Susan Drapeau , Qingshan (Sam) Ye
发明人： William Donofrio , Jeffrey Nycz , Can Cinbis , Matthew Morrison , Susan Drapeau , Qingshan (Sam) Ye
IPC分类号： A61B8/00
CPC分类号： A61B8/0875 , A61B5/076 , A61B5/4509 , A61B5/4528 , A61B5/6882 , A61B7/005 , A61B7/006 , A61B8/4472 , A61B8/56 , A61B8/565
摘要： An implantable sensor for detecting changes in tissue density is disclosed. The implantable sensor includes a transducer adapted for detecting indicators of tissue density. The implantable sensor includes memory for storing data corresponding to the tissue density indicators detected by the sensor. A telemetry circuit is configured for transmitting the tissue density data outside of the body.
摘要翻译：公开了一种用于检测组织密度变化的植入式传感器。可植入传感器包括适于检测组织密度指标的换能器。可植入传感器包括用于存储对应于由传感器检测的组织密度指示符的数据的存储器。遥测电路被配置用于将身体外的组织密度数据传输。

5. 发明申请

US20070197895A1 Surgical instrument to assess tissue characteristics 审中-公开
标题翻译：手术器械评估组织特征
公开(公告)号：US20070197895A1
公开(公告)日：2007-08-23
申请号：US11356643
申请日：2006-02-17
申请人： Jeffrey Nycz , Fred Molz , Steven Tethrake , Stanley Olson , William Donofrio
发明人： Jeffrey Nycz , Fred Molz , Steven Tethrake , Stanley Olson , William Donofrio
IPC分类号： A61B5/05 , A61B17/00 , A61B8/00
CPC分类号： A61B8/0875 , A61B5/4504 , A61B5/4509 , A61B8/12 , A61B8/4245 , A61B8/4472 , A61B8/4483 , A61B8/483 , A61B8/5223 , A61B17/1703 , A61B17/56 , A61B17/8805
摘要： A surgical instrument for assessing tissue characteristics such as tissue density and volume is disclosed. The surgical instrument is hand-held and includes transducers adapted for emitting and/or receiving acoustic signals. The surgical instrument utilizes pulse-echo to determine tissue characteristics. The surgical instrument may be utilized to determine such things as the size of a lesion and whether the lesion has been completely removed or filled with graft material.
摘要翻译：公开了一种用于评估组织特征如组织密度和体积的手术器械。手术器械是手持式的并且包括适于发射和/或接收声信号的换能器。手术器械利用脉冲回波来确定组织特征。可以使用外科器械来确定诸如损伤的大小以及病变是否已被完全去除或用移植材料填充的东西。

6. 发明申请

US20060081259A1 Medical effector system 有权
标题翻译：医疗效应器系统
公开(公告)号：US20060081259A1
公开(公告)日：2006-04-20
申请号：US11158161
申请日：2005-06-21
申请人： Paul Bruggeman , Mark Burdorff , William Collins , William Donofrio , Curt Eyster , Hal Katz , James Martin , Anil Nalagatla , Paul Niklewski , Salvatore Privitera , Fred Stevens , Jeffery Wuennemann , Randall Hickle
发明人： Paul Bruggeman , Mark Burdorff , William Collins , William Donofrio , Curt Eyster , Hal Katz , James Martin , Anil Nalagatla , Paul Niklewski , Salvatore Privitera , Fred Stevens , Jeffery Wuennemann , Randall Hickle
IPC分类号： A61M15/08
CPC分类号： A61M5/142 , A61B5/0836 , A61B5/411 , A61B5/6819 , A61B5/682 , A61B5/7495 , A61M5/14228 , A61M5/162 , A61M5/16831 , A61M5/172 , A61M16/0051 , A61M16/024 , A61M16/0493 , A61M16/0672 , A61M16/0677 , A61M16/0688 , A61M16/0808 , A61M16/085 , A61M16/0858 , A61M21/02 , A61M2016/0027 , A61M2016/1025 , A61M2021/0027 , A61M2202/0208 , A61M2202/048 , A61M2202/062 , A61M2205/05 , A61M2205/12 , A61M2205/123 , A61M2205/13 , A61M2205/14 , A61M2205/273 , A61M2205/3334 , A61M2205/3553 , A61M2205/3561 , A61M2205/3584 , A61M2205/505 , A61M2205/6072 , A61M2205/7536 , A61M2209/084 , A61M2210/0618 , A61M2210/0625 , A61M2210/0662 , A61M2230/04 , A61M2230/06 , A61M2230/205 , A61M2230/30 , A61M2230/432 , A61M2230/63 , G06F19/00 , G06Q50/22 , G06Q50/24
摘要： A medical effector system comprised of a bedside unit and a procedure unit. The bedside unit contains a series of connection points for receiving inputs from a series of patient monitors. The procedure unit contains a patient monitoring and medical effector program, and a drug delivery pump or magnetic flux generator capable of delivering therapeutic energy to a patient. The medical effector system contains the capability to issue and receive a request from a non-sedated patient, issue and receive a request from a sedated patient and then to calculate a time difference. The medical effector program operates the pump or magnetic flux generator based upon at least some of the patient outputs and program inputs including a calculated time difference. A removable umbilical cable connects the two units and allows the output of the patient monitors as well as other information to travel between the two units.
摘要翻译：包括床边单元和程序单元的医疗执行器系统。床边单元包含一系列连接点，用于接收来自一系列病人监护仪的输入。程序单元包括患者监测和医疗效应器程序，以及能够将治疗能量递送给患者的药物输送泵或磁通量发生器。医疗执行器系统包含发出和接收来自非镇静患者的请求的能力，发出并接收来自镇静患者的请求，然后计算时间差。医疗效应器程序基于患者输出和程序输入中的至少一些包括计算出的时间差来操作泵或磁通量发生器。可拆卸的脐带电缆连接两个单元，并允许患者监护仪的输出以及其他信息在两个单元之间行进。

7. 发明申请

US20050066970A1 Response testing for conscious sedation using cableless communication 审中-公开
标题翻译：使用无线通信进行意识镇静的反应测试
公开(公告)号：US20050066970A1
公开(公告)日：2005-03-31
申请号：US10671183
申请日：2003-09-25
申请人： William Donofrio
发明人： William Donofrio
IPC分类号： A61B5/00 , A61B5/0205 , A61B5/0488 , A61B5/083 , A61B5/11 , A61B5/22 , A61M16/00 , A61M16/01 , A61M16/06 , A62B7/00
CPC分类号： A61B5/6826 , A61B5/0002 , A61B5/0205 , A61B5/0488 , A61B5/0836 , A61B5/1106 , A61B5/1455 , A61B5/224 , A61B5/4821 , A61B5/6803 , A61B5/6815 , A61B5/6838 , A61M16/01 , A61M16/0666 , A61M16/0683 , A61M2016/0021 , A61M2205/3375 , A61M2205/3569 , A61M2205/3592 , A61M2230/205 , A61M2230/30 , A61M2230/432 , A61M2230/60 , A61M2230/63
摘要： A conscious sedation system and a response testing apparatus for a conscious sedation system. The response testing apparatus includes a request assembly and a response assembly. The request assembly communicates to a patient a request generated by a controller of the conscious sedation system for a predetermined response from the patient. The response assembly senses a response made by the patient to the request and communicates the response to the controller which analyses at least the response to determine a level of sedation of the patient. At least one of the request assembly and the response assembly includes a cableless communication device which communicates at least one of the request and the response between the controller and the patient.
摘要翻译：有意义的镇静系统和有意义的镇静系统的反应测试仪器。响应测试装置包括请求组件和响应组件。请求组件与病人通过意识的镇静系统的控制器产生的请求，从病人的预定响应中传达请求。响应组件感测患者对该请求的响应，并且将响应传达给控制器，该控制器至少分析响应以确定患者的镇静水平。请求组件和响应组件中的至少一个包括无线通信设备，其在控制器和患者之间通信请求和响应中的至少一个。

8. 发明申请

US20070179739A1 IMPLANTABLE PEDOMETER 失效
标题翻译：可植入的PEDOMETER
公开(公告)号：US20070179739A1
公开(公告)日：2007-08-02
申请号：US11344999
申请日：2006-02-01
申请人： William Donofrio , Jeffrey Nycz , Sarah Audet , Can Cinbis , Michael Schugt , Gerard Hill , Qingshan Ye
发明人： William Donofrio , Jeffrey Nycz , Sarah Audet , Can Cinbis , Michael Schugt , Gerard Hill , Qingshan Ye
IPC分类号： G01C22/00 , G01B11/02 , G01B11/14
CPC分类号： A61B5/4528 , A61B5/1118 , A61B5/1123 , A61B5/686 , A61B17/86 , A61B2562/0219 , A61F2/2803 , A61F2/32 , A61F2/34 , A61F2/36 , A61F2/3676 , A61F2/38 , A61F2/3804 , A61F2/40 , A61F2/4202 , A61F2/4261 , A61F2/44 , A61F2/4603 , A61F2/4657 , A61F2002/30448 , A61F2002/3067 , A61F2002/30794 , A61F2002/3085 , A61F2002/3403 , A61F2002/3429 , A61F2002/3611 , A61F2002/3625 , A61F2002/365 , A61F2002/4666 , A61F2002/488 , A61F2220/005 , A61F2250/0002
摘要： An implantable pedometer for measuring the amount of joint use is disclosed. The implantable pedometer includes a sensor adapted for detecting indicators of joint usage. A counter is configured for storing count data corresponding to the number of indicators detected by the sensor and a telemetry circuit is configured for transmitting the count data outside of the body.
摘要翻译：公开了一种用于测量联合使用量的可植入计步器。可植入计步器包括适于检测联合使用指标的传感器。计数器被配置为存储与由传感器检测到的指示符的数量相对应的计数数据，并且遥测电路被配置为在体外发送计数数据。

9. 发明申请

US20070048655A1 Preparation of suspension polymerized toners 失效
标题翻译：悬浮聚合调色剂的制备
公开(公告)号：US20070048655A1
公开(公告)日：2007-03-01
申请号：US11209454
申请日：2005-08-23
申请人： Bing Hsieh , William Donofrio
发明人： Bing Hsieh , William Donofrio
IPC分类号： G03G9/08
CPC分类号： G03G9/0806 , G03G9/0819 , G03G9/08782 , G03G9/0906 , G03G9/09725 , G03G9/09733
摘要： The invention relates to a process for the preparation of a dry toner powder containing a wax component and formed using a limited coalescence suspension polymerization process. Both conventional and aqueous dispersed waxes may be used to form the toner particles. Likewise, both dry and aqueous dispersed pigments may be used. The resulting toner provides properties desired in the next generation of toners including small uniform particle size as well as desirable anti-blocking and high-temperature anti-offset properties.
摘要翻译：本发明涉及一种制备含有蜡组分并使用有限聚结悬浮聚合方法形成的干调色剂粉末的方法。可以使用常规和水分散的蜡来形成调色剂颗粒。同样，也可以使用干燥和水分散的颜料。所得到的调色剂提供下一代调色剂所需的性能，包括小均匀的粒度以及所需的防粘连和高温抗胶印性能。

10. 发明申请

US20050070822A1 Response testing for conscious sedation utilizing a hand motion response 审中-公开
标题翻译：使用手运动反应进行意识镇静的反应测试
公开(公告)号：US20050070822A1
公开(公告)日：2005-03-31
申请号：US10673660
申请日：2003-09-29
申请人： William Donofrio , Stephen Balek , Anil Nalagatla , Michael Gustafson
发明人： William Donofrio , Stephen Balek , Anil Nalagatla , Michael Gustafson
IPC分类号： A61B5/00 , A61B5/0205 , A61B5/0488 , A61B5/083 , A61B5/11 , A61B5/22 , A61M16/00 , A61M16/01 , A61M16/06 , A61B5/103
CPC分类号： A61B5/6826 , A61B5/0002 , A61B5/0205 , A61B5/0488 , A61B5/0836 , A61B5/1106 , A61B5/1455 , A61B5/224 , A61B5/4821 , A61B5/6803 , A61B5/6815 , A61B5/6838 , A61M16/01 , A61M16/0666 , A61M16/0683 , A61M2016/0021 , A61M2205/3375 , A61M2205/3569 , A61M2205/3592 , A61M2230/205 , A61M2230/30 , A61M2230/432 , A61M2230/60 , A61M2230/63
摘要： A conscious sedation system and a response testing apparatus for a conscious sedation system. A controller generates a request for a predetermined hand motion response from a patient and analyses at least a hand motion response made by the patient to the request to determine a level of sedation of the patient. The response testing apparatus includes a request assembly and a response assembly. The request assembly communicates to the patient the request generated by the controller. The response assembly senses the hand motion response and communicates the hand motion response to the controller.
摘要翻译：有意义的镇静系统和有意义的镇静系统的反应测试仪器。控制器产生来自患者的预定手运动响应的请求，并且分析至少由患者做出的手运动响应以确定患者的镇静水平的请求。响应测试装置包括请求组件和响应组件。请求组件向患者传达由控制器产生的请求。响应组件感测手的运动响应并将手运动响应传达给控制器。

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