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1. 发明授权

US07601286B2 Polymer-based platform for microfluidic systems 有权
公开(公告)号：US07601286B2
公开(公告)日：2009-10-13
申请号：US10107933
申请日：2002-03-26
申请人： William Benett , Peter Krulevitch , Mariam Maghribi , Julie Hamilton , Klint Rose , Amy W. Wang
发明人： William Benett , Peter Krulevitch , Mariam Maghribi , Julie Hamilton , Klint Rose , Amy W. Wang
IPC分类号： B29C33/76
CPC分类号： B29C39/10 , B29C33/3842 , B29C39/34 , B29K2083/00 , B29K2083/005 , B29L2031/24 , B29L2031/756
摘要： A method of forming a polymer-based microfluidic system platform using network building blocks selected from a set of interconnectable network building blocks, such as wire, pins, blocks, and interconnects. The selected building blocks are interconnectably assembled and fixedly positioned in precise positions in a mold cavity of a mold frame to construct a three-dimensional model construction of a microfluidic flow path network preferably having meso-scale dimensions. A hardenable liquid, such as poly (dimethylsiloxane) is then introduced into the mold cavity and hardened to form a platform structure as well as to mold the microfluidic flow path network having channels, reservoirs and ports. Pre-fabricated elbows, T's and other joints are used to interconnect various building block elements together. After hardening the liquid the building blocks are removed from the platform structure to make available the channels, cavities and ports within the platform structure. Microdevices may be embedded within the cast polymer-based platform, or bonded to the platform structure subsequent to molding, to create an integrated microfluidic system. In this manner, the new microfluidic platform is versatile and capable of quickly generating prototype systems, and could easily be adapted to a manufacturing setting.

2. 发明申请

US20060113537A1 Electronic unit integrated into a flexible polymer body 有权
公开(公告)号：US20060113537A1
公开(公告)日：2006-06-01
申请号：US11326967
申请日：2006-01-05
申请人： Peter Krulevitch , Mariam Maghribi , William Benett , Julie Hamilton , Klint Rose , James Davidson , Mark Strauch
发明人： Peter Krulevitch , Mariam Maghribi , William Benett , Julie Hamilton , Klint Rose , James Davidson , Mark Strauch
IPC分类号： H01L31/0376
CPC分类号： H01L25/165 , B81C1/0023 , H01L21/6835 , H01L31/048 , H01L31/0543 , H01L2221/68345 , H01L2924/0002 , H01L2924/09701 , H01L2924/19041 , H01L2924/19105 , Y02E10/52 , H01L2924/00
摘要： A peel and stick electronic system comprises a silicone body, and at least one electronic unit operatively connected to the silicone body. The electronic system is produce by providing a silicone layer on a substrate, providing a metal layer on the silicone layer, and providing at least one electronic unit connected to the metal layer.

3. 发明申请

US20050030698A1 Electronic unit integrated into a flexible polymer body 有权
标题翻译：电子单元集成到柔性聚合物体内
公开(公告)号：US20050030698A1
公开(公告)日：2005-02-10
申请号：US10939771
申请日：2004-09-13
申请人： Peter Krulevitch , Mariam Maghribi , William Benett , Julie Hamilton , Klint Rose , James Davidson , Mark Strauch
发明人： Peter Krulevitch , Mariam Maghribi , William Benett , Julie Hamilton , Klint Rose , James Davidson , Mark Strauch
IPC分类号： A61N1/04 , A61N1/05 , H01L23/538 , H01L25/065 , H05K1/00 , H05K1/03 , H01G4/30
CPC分类号： A61N1/0456 , A61B2560/0412 , A61N1/0452 , A61N1/0476 , A61N1/0492 , A61N1/05 , A61N1/0534 , H01L23/5387 , H01L25/065 , H01L2924/0002 , H01L2924/09701 , H05K1/0313 , H05K1/0393 , H05K2201/0162 , H05K2201/09118 , H01L2924/00
摘要： A peel and stick electronic system comprises a silicone body, and at least one electronic unit operatively connected to the silicone body. The electronic system is produce by providing a silicone layer on a substrate, providing a metal layer on the silicone layer, and providing at least one electronic unit connected to the metal layer.
摘要翻译：剥离和粘贴电子系统包括硅树脂体和至少一个可操作地连接到硅氧烷体的电子单元。该电子系统是通过在衬底上提供硅树脂层，在硅树脂层上提供金属层，并提供至少一个与金属层连接的电子单元来制造的。

4. 发明申请

US20050136639A1 Pin-deposition of conductive inks for microelectrodes and contact via filling 有权
标题翻译：用于微电极的导电油墨的引脚沉积和通过填充的接触
公开(公告)号：US20050136639A1
公开(公告)日：2005-06-23
申请号：US10742112
申请日：2003-12-18
申请人： J. Davidson , Peter Krulevitch , Mariam Maghribi , Julie Hamilton , William Benett , Armando Tovar
发明人： J. Davidson , Peter Krulevitch , Mariam Maghribi , Julie Hamilton , William Benett , Armando Tovar
IPC分类号： H01L21/44 , H01L21/768 , H05K3/40
CPC分类号： H01L21/76838 , H05K3/4053 , H05K2203/0195 , H05K2203/0338 , Y10T29/49155
摘要： A system for metalization of an integrated microsystem. The system comprises providing a substrate and applying a conductive material to the substrate by taking up small aliquots of conductive material and releasing the conductive material onto the substrate to produce a circuit component.
摘要翻译：一个集成微系统的金属化系统。该系统包括提供衬底并且通过吸收导电材料的小等分试样并将导电材料释放到衬底上以产生电路部件而将导电材料施加到衬底。

5. 发明授权

US07186352B2 Microfluidic systems with embedded materials and structures and method thereof 失效
标题翻译：具有嵌入材料和结构的微流体系统及其方法
公开(公告)号：US07186352B2
公开(公告)日：2007-03-06
申请号：US10853859
申请日：2004-05-25
申请人： Jeffrey D. Morse , Klint A Rose , Mariam Maghribi , William Benett , Peter Krulevitch , Julie Hamilton , Robert T. Graff , Alan Jankowski
发明人： Jeffrey D. Morse , Klint A Rose , Mariam Maghribi , William Benett , Peter Krulevitch , Julie Hamilton , Robert T. Graff , Alan Jankowski
IPC分类号： H01M8/00
CPC分类号： B01D67/0034 , B01D65/003 , B01D67/0032 , B01D71/70 , B01D2323/24 , B01D2325/028 , B01D2325/08 , H01M8/0239 , H01M8/0245 , H01M8/04037 , H01M8/04089 , H01M8/1007 , H01M8/1097 , Y10T29/49114
摘要： Described herein is a process for fabricating microfluidic systems with embedded components in which micron-scale features are molded into the polymeric material polydimethylsiloxane (PDMS). Micromachining is used to create a mold master and the liquid precursors for PDMS are poured over the mold and allowed to cure. The PDMS is then removed form the mold and bonded to another material such as PDMS, glass, or silicon after a simple surface preparation step to form sealed microchannels.
摘要翻译：本文描述了一种用于制造具有嵌入组件的微流体系统的方法，其中将微米级特征模制成聚合物材料聚二甲基硅氧烷（PDMS）。微加工用于制造模具主体，将PDMS的液体前体倒在模具上并使其固化。然后在简单的表面制备步骤之后，从模具中除去PDMS并结合到另一种材料如PDMS，玻璃或硅，以形成密封的微通道。

6. 发明申请

US20060029731A1 Conductive inks for metalization in integrated polymer microsystems 有权
公开(公告)号：US20060029731A1
公开(公告)日：2006-02-09
申请号：US11243302
申请日：2005-10-03
申请人： James Davidson , Peter Krulevitch , Mariam Maghribi , William Benett , Julie Hamilton , Armando Tovar
发明人： James Davidson , Peter Krulevitch , Mariam Maghribi , William Benett , Julie Hamilton , Armando Tovar
IPC分类号： B05D3/12 , B05D5/00 , B05D1/02 , B05D3/02
CPC分类号： H01L23/145 , H01L23/5387 , H01L2924/0002 , H01L2924/1433 , H05K1/0272 , H05K1/0283 , H05K1/032 , H05K1/0393 , H05K1/095 , H05K3/101 , H05K3/12 , H05K3/1216 , H05K3/1258 , H05K3/1275 , H05K2201/0162 , H05K2203/0108 , H05K2203/0126 , H05K2203/082 , Y10S428/901 , Y10T428/24917 , H01L2924/00
摘要： A system of metalization in an integrated polymer microsystem. A flexible polymer substrate is provided and conductive ink is applied to the substrate. In one embodiment the flexible polymer substrate is silicone. In another embodiment the flexible polymer substrate comprises poly(dimethylsiloxane).

7. 发明授权

US06921603B2 Microfluidic fuel cell systems with embedded materials and structures and method thereof 失效
标题翻译：具有嵌入材料和结构的微流体燃料电池系统及其方法
公开(公告)号：US06921603B2
公开(公告)日：2005-07-26
申请号：US10131846
申请日：2002-04-24
申请人： Jeffrey D. Morse , Klint A Rose , Mariam Maghribi , William Benett , Peter Krulevitch , Julie Hamilton , Robert T. Graff , Alan Jankowski
发明人： Jeffrey D. Morse , Klint A Rose , Mariam Maghribi , William Benett , Peter Krulevitch , Julie Hamilton , Robert T. Graff , Alan Jankowski
IPC分类号： B01D65/00 , B01D67/00 , B01D71/70 , H01M4/86 , H01M8/00 , H01M8/02 , H01M8/04 , H01M8/10
CPC分类号： B01D67/0034 , B01D65/003 , B01D67/0032 , B01D71/70 , B01D2323/24 , B01D2325/028 , B01D2325/08 , H01M8/0239 , H01M8/0245 , H01M8/04037 , H01M8/04089 , H01M8/1007 , H01M8/1097 , Y10T29/49114
摘要： Described herein is a process for fabricating microfluidic systems with embedded components in which micron-scale features are molded into the polymeric material polydimethylsiloxane (PDMS). Micromachining is used to create a mold master and the liquid precursors for PDMS are poured over the mold and allowed to cure. The PDMS is then removed form the mold and bonded to another material such as PDMS, glass, or silicon after a simple surface preparation step to form sealed microchannels.
摘要翻译：本文描述了一种用于制造具有嵌入组件的微流体系统的方法，其中将微米级特征模制成聚合物材料聚二甲基硅氧烷（PDMS）。微加工用于制造模具主体，将PDMS的液体前体倒在模具上并使其固化。然后在简单的表面制备步骤之后，从模具中除去PDMS并结合到另一种材料如PDMS，玻璃或硅，以形成密封的微通道。

8. 发明申请

US20050029308A1 System for dispensing a precise amount of fluid 失效
标题翻译：用于分配精确量的流体的系统
公开(公告)号：US20050029308A1
公开(公告)日：2005-02-10
申请号：US10621657
申请日：2003-07-16
申请人： William Benett , Peter Krulevitch , Steven Visuri , John Dzenitis , Kevin Ness
发明人： William Benett , Peter Krulevitch , Steven Visuri , John Dzenitis , Kevin Ness
IPC分类号： B01L3/02 , G01N1/00 , G01N35/10 , B67D5/42
CPC分类号： B01L3/0217 , B01L2400/0487 , G01N35/1016 , G01N35/1065 , G01N2035/1034
摘要： A dispensing system delivers a precise amount of fluid for biological or chemical processing and/or analysis. Dispensing means moves the fluid. The dispensing means is operated by a pneumatic force. Connection means delivers the fluid to the desired location. An actuator means provides the pneumatic force to the dispensing means. Valving means transmits the pneumatic force from the actuator means to the dispensing means.
摘要翻译：分配系统提供精确量的用于生物或化学处理和/或分析的流体。分液装置移动流体。分配装置通过气动力操作。连接装置将流体输送到所需位置。致动器装置向分配装置提供气动力。阀装置将气动力从致动器装置传递到分配装置。

9. 发明申请

US20070066939A1 Electrokinetic Infusion Pump System 审中-公开
标题翻译：电动输液泵系统
公开(公告)号：US20070066939A1
公开(公告)日：2007-03-22
申请号：US11532587
申请日：2006-09-18
申请人： Peter Krulevitch , William Benett , Neil Roberts , Sebastian Bohm , Zara Sieh
发明人： Peter Krulevitch , William Benett , Neil Roberts , Sebastian Bohm , Zara Sieh
IPC分类号： A61M1/00
CPC分类号： A61M5/14244 , A61M5/14248 , A61M5/1452 , A61M5/16831 , A61M5/172 , A61M2005/14513 , A61M2205/3317 , A61M2205/3389
摘要： Various methods and devices are provided for delivering an infusion liquid using an electrokinetic infusion pump. The electrokinetic infusion pump can generally include an infusion housing having an infusion reservoir. The infusion reservoir has an infusion outlet and is capable of containing an infusion liquid. A plunger is movably coupled to the infusion housing and is adapted to be manually displaced relative to the infusion housing to load the infusion reservoir with infusion liquid. A movable partition can be disposed within the infusion housing and has a first surface in communication with an electrokinetic solution and a second surface, isolated from the first surface, in communication with the infusion reservoir. The electrokinetic infusion pump can further include an electrokinetic engine integrated within the plunger and adapted to selectively deliver electric potential across an electrokinetic porous media to cause the electrokinetic solution within the electrokinetic engine to displace the movable partition to effect delivery of at least a portion of the infusion liquid through the infusion outlet.
摘要翻译：提供用于使用电动输液泵输送输液的各种方法和装置。电动输液泵通常可以包括具有输注储器的输注外壳。输注槽具有输液口，并且能够容纳输液。柱塞可移动地联接到输注壳体，并且适于相对于输注壳体手动移位以用输注液体加载输注储存器。可移动隔板可以设置在输注外壳内，并且具有与电动溶液连通的第一表面和与第一表面隔离的与输注储存器连通的第二表面。电动输液泵还可以包括集成在柱塞内的电动发动机，并且适于选择性地跨电动多孔介质输送电势，以使电动发动机内的电动溶液移动可动隔板，从而实现至少一部分输液通过输液口。

10. 发明申请

US20080019657A1 System for diffusing light from an optical fiber or light guide 有权
标题翻译：用于漫射光纤或光导的光的系统
公开(公告)号：US20080019657A1
公开(公告)日：2008-01-24
申请号：US11489138
申请日：2006-07-18
申请人： Duncan Maitland , Ward Small , Thomas Wilson , William Benett
发明人： Duncan Maitland , Ward Small , Thomas Wilson , William Benett
IPC分类号： G02B6/00 , G02B6/26 , G02B6/42
CPC分类号： G02B6/262 , G02B6/0008
摘要： A system for diffusing light from an optical fiber wherein the optical fiber is coupled to a light source, comprising forming a polymer element adapted to be connected to the optical fiber and incorporating a scattering element with the polymer element wherein the scattering element diffuses the light from the polymer element. The apparatus of the present invention comprises a polymer element operatively connected to the optical fiber and a scattering element operatively connected with the shape polymer element that diffuses the light from the polymer element.
摘要翻译：一种用于从光纤漫射光的系统，其中所述光纤耦合到光源，包括形成适于连接到所述光纤的聚合物元件并且与所述聚合物元件结合散射元件，其中所述散射元件将来自聚合物元素。本发明的装置包括可操作地连接到光纤的聚合物元件和与聚合物元件的光扩散的形状聚合物元件可操作地连接的散射元件。

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