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1. 发明申请

US20070266462A1 COMPOSITIONS RELATED TO THE QUANTITATIVE TRAIT LOCUS 6 (QTL6) IN MAIZE AND METHODS OF USE 有权
标题翻译：与量化条件6（QTL6）相关的组合物及其使用方法
公开(公告)号：US20070266462A1
公开(公告)日：2007-11-15
申请号：US11680922
申请日：2007-03-01
申请人： William Allen , Bo Shen , Mitchell Tarczynski , Mark Williams , Peizhong Zheng , Gan-Yuan Zhong
发明人： William Allen , Bo Shen , Mitchell Tarczynski , Mark Williams , Peizhong Zheng , Gan-Yuan Zhong
IPC分类号： A01H9/00 , A01H1/00 , A01H11/00 , C07K14/00 , C12N15/82 , C07H21/00 , A01H5/00
CPC分类号： C12N15/8247 , C12N9/1029 , C12Q1/6895 , C12Q2600/13 , C12Q2600/156 , C12Q2600/172
摘要： Compositions related to the quantitative trait locus 6 (QTL6) in maize and methods for their use are provided. The compositions are novel molecular marker loci that are genetically linked with QTL6 and which are associated with increased oil content and/or increased oleic acid content and/or an increased oleic acid/linoleic acid ratio of a plant or plant part thereof. These novel markers are characterized by the presence of at least one polymorphism relative to the corresponding marker locus from the QTL6 region of non-high-oil, non-high-oleic acid maize plants. In some embodiments, the novel marker loci comprise coding sequence for a maize DGAT1-2 polypeptide or biologically active variant thereof. The marker loci of the invention, and suitable fragments thereof, are useful in methods of the invention for manipulating oil and/or oleic acid content and/or oleic acid/lineolic acid ratio of a plant or plant part thereof, for marker-assisted selection of a plant, for example, a maize plant, or plant part thereof, having an increased oil content and/or increased oleic acid content and/or an increased oleic acid/linoleic acid ratio, and for marker-assisted breeding of the high oil and/or high oleic acid trait.
摘要翻译：提供了与玉米数量性状基因座6（QTL6）相关的成分及其使用方法。所述组合物是与QTL6遗传连锁的新型分子标记基因座，其与植物或植物部分的油含量增加和/或油酸含量增加和/或油酸/亚油酸含量增加相关。这些新型标记物的特征在于相对于非高油非高油酸玉米植物的QTL6区域的相应标记基因座存在至少一个多态性。在一些实施方案中，新的标记基因座包含玉米DGAT1-2多肽或其生物活性变体的编码序列。本发明的标记基因座及其合适的片段可用于本发明的操作用于标记辅助选择的植物或植物部分的油和/或油酸含量和/或油酸/线性酸比例的方法中具有增加的油含量和/或油酸含量增加和/或油酸/亚油酸比例增加的植物，例如玉米植物或其植物部分，以及高油的标记辅助育种和/或高油酸性状。

2. 发明申请

US20070294781A1 COMPOSITIONS RELATED TO THE QUANTITATIVE TRAIT LOCUS 6 (QTL6) IN MAIZE AND METHODS OF USE 有权
公开(公告)号：US20070294781A1
公开(公告)日：2007-12-20
申请号：US11680906
申请日：2007-03-01
申请人： William Allen , Bo Shen , Mitchell Tarczynski , Mark Williams , Peizhong Zheng , Gan-Yuan Zhong
发明人： William Allen , Bo Shen , Mitchell Tarczynski , Mark Williams , Peizhong Zheng , Gan-Yuan Zhong
IPC分类号： A01H1/04 , A01H5/00 , C07H21/02 , C12Q1/68
CPC分类号： A01H1/04 , C12N9/1029 , C12N15/8247 , C12Q1/6895 , C12Q2600/13 , C12Q2600/156 , C12Q2600/172 , Y10T436/104165
摘要： Compositions related to the quantitative trait locus 6 (QTL6) in maize and methods for their use are provided. The compositions are novel molecular marker loci that are genetically linked with QTL6 and which are associated with increased oil content and/or increased oleic acid content and/or an increased oleic acid/linoleic acid ratio of a plant or plant part thereof. These novel markers are characterized by the presence of at least one polymorphism relative to the corresponding marker locus from the QTL6 region of non-high-oil, non-high-oleic acid maize plants. In some embodiments, the novel marker loci comprise coding sequence for a maize DGAT1-2 polypeptide or biologically active variant thereof. The marker loci of the invention, and suitable fragments thereof, are useful in methods of the invention for manipulating oil and/or oleic acid content and/or oleic acid/lineolic acid ratio of a plant or plant part thereof, for marker-assisted selection of a plant, for example, a maize plant, or plant part thereof, having an increased oil content and/or increased oleic acid content and/or an increased oleic acid/linoleic acid ratio, and for marker-assisted breeding of the high oil and/or high oleic acid trait.

3. 发明申请

US20070022499A1 Alteration of oil traits in plants 审中-公开
标题翻译：改变植物油性状
公开(公告)号：US20070022499A1
公开(公告)日：2007-01-25
申请号：US11526171
申请日：2006-09-22
申请人： William Allen , Rebecca Cahoon , Sabine Epelbaum , Igor Oliveira , Bo Shen , Mitchell Tarczynski
发明人： William Allen , Rebecca Cahoon , Sabine Epelbaum , Igor Oliveira , Bo Shen , Mitchell Tarczynski
IPC分类号： A01H1/00 , C07H21/04 , C12N15/82 , C12N5/04
CPC分类号： C12N15/8247 , C07K14/415
摘要： The preparation and use of nucleic acid fragments useful in altering the oil phenotype in plants are disclosed. Chimeric constructs incorporating such nucleic acid fragments and suitable regulatory sequences can be used to create transgenic plants having altered lipid profiles. Methods for altering the oil phenotype in plants using such nucleic acid fragments also are disclosed.
摘要翻译：公开了可用于改变植物油表型的核酸片段的制备和使用。掺入此类核酸片段和合适调节序列的嵌合构建体可用于产生具有改变的脂质谱的转基因植物。还公开了使用这种核酸片段改变植物油表型的方法。

4. 发明申请

US20190331936A1 Illuminated Lens Frame 审中-公开
公开(公告)号：US20190331936A1
公开(公告)日：2019-10-31
申请号：US15962026
申请日：2018-04-25
申请人： William Allen
发明人： William Allen
IPC分类号： G02C11/04 , G02C11/02 , F21V23/00 , G03B21/00
摘要： An illuminated eyewear includes a lens support including a frame with a pair of rims and a bridge that is attached to and extends between the rims. A first temple is attached to one of the rims and a second temple is attached to another one of the rims. A pair of lenses is mounted to the frame wherein each of the rims engages one of the lenses. A light source is mounted on the lens support and illuminating perimeter edges of the lenses when the light source is turned on.

5. 发明授权

US08690904B2 Percutaneous access conduit 有权
标题翻译：经皮导管
公开(公告)号：US08690904B2
公开(公告)日：2014-04-08
申请号：US11893853
申请日：2007-08-18
申请人： Jeffrey Grayzel , Joseph Grayzel , William Allen , Fred Karl , Alan Bachman , Ray Adams
发明人： Jeffrey Grayzel , Joseph Grayzel , William Allen , Fred Karl , Alan Bachman , Ray Adams
IPC分类号： A61B17/32 , A61F11/00
CPC分类号： A61B17/02 , A61B17/0057 , A61B17/2812 , A61B17/282 , A61B17/3403 , A61B17/3439 , A61B2017/00424 , A61B2017/00654 , A61B2017/00778 , A61B2017/320044 , A61B2017/3405 , A61B2090/062 , A61B2090/306
摘要： A tubular conduit is used to access blood vessels or other structures in the human body. The conduit has a distal tip angled to match the angle of entry into the body and an end contour adapted for the surface of the target vessel or organ. The contour may be curved to match the curve on the outer surface of the vessel or organ. The conduit's angled and contoured distal end may be adapted to engage, and align the conduit with, the surface of the vessel or organ. The conduit bears a longitudinal groove along its lower, inner surface. When the conduit is appropriately aligned, the groove may be used to guide a needle tip to the desired location, for example, the mid-line of the vessel or organ.
摘要翻译：管状导管用于进入人体内的血管或其他结构。导管具有成角度的远端以匹配进入体内的角度以及适于目标血管或器官表面的端部轮廓。轮廓可以弯曲以匹配血管或器官的外表面上的曲线。导管的成角度和轮廓的远端可以适于将导管与容器或器官的表面接合并对齐。导管沿其下部内表面具有纵向凹槽。当导管适当地对准时，凹槽可用于将针尖引导到所需位置，例如容器或器官的中线。

6. 发明授权

US08461244B2 Intumescent coating compositions 有权
标题翻译：膨胀型涂料组合物
公开(公告)号：US08461244B2
公开(公告)日：2013-06-11
申请号：US11722347
申请日：2005-12-21
申请人： Andrew Philip Taylor , Simon Butterfield , John Darryl Green , William Allen
发明人： Andrew Philip Taylor , Simon Butterfield , John Darryl Green , William Allen
IPC分类号： C08K3/34
CPC分类号： C09D5/185
摘要： A liquid intumescent resin coating composition including at least one polymeric component, at least one ethylenically unsaturated monomeric component, and at least one intumescent ingredient. The coating composition further includes at least one of Sodium Potassium Aluminum Silicate (Nepheline syenite) and Potassium Aluminum Silicate. The coating composition is curable to a solid state by free radical polymerization.
摘要翻译：一种液体膨胀型树脂涂料组合物，其包含至少一种聚合物组分，至少一种烯属不饱和单体组分和至少一种膨胀成分。涂料组合物还包括硅铝酸钠（霞石正长岩）和硅酸铝钾中的至少一种。涂料组合物可通过自由基聚合固化成固态。

7. 发明申请

US20120143217A1 METHOD AND APPARATUS FOR CIRCULATORY VALVE REPAIR 有权
标题翻译：循环阀维修方法与装置
公开(公告)号：US20120143217A1
公开(公告)日：2012-06-07
申请号：US13370690
申请日：2012-02-10
申请人： MEHMET C. OZ , Gerald M. Lemole , Alan Lotvin , Juan P. Umana , William Allen , Howard P. Levin
发明人： MEHMET C. OZ , Gerald M. Lemole , Alan Lotvin , Juan P. Umana , William Allen , Howard P. Levin
IPC分类号： A61B17/10
CPC分类号： A61B17/0686 , A61B17/064 , A61B17/0644 , A61B17/08 , A61B17/10 , A61B17/122 , A61B17/1285 , A61B2017/00243 , A61B2017/0649 , A61F2/2427
摘要： An apparatus for the repair of a cardiovascular valve has leaflets comprising a grasper capable of grabbing and co-apting the leaflets of the valve. In a preferred embodiment, the grasper has jaws that grasp and immobilize the leaflets, and then a fastener is inserted to co-apt the leaflets. The apparatus is particularly useful for repairing mitral valves to cure mitral regurgitation.
摘要翻译：用于修复心血管瓣膜的装置具有包括能够抓住和共同锁定瓣膜的小叶片的抓紧器的小叶。在优选实施例中，抓紧器具有抓住和固定传单的钳口，然后将紧固件插入以与传单共同适配。该装置特别适用于修复二尖瓣以治愈二尖瓣反流。

8. 发明授权

US08133239B2 Method and apparatus for circulatory valve repair 有权
标题翻译：循环瓣膜修复方法和装置
公开(公告)号：US08133239B2
公开(公告)日：2012-03-13
申请号：US12209336
申请日：2008-09-12
申请人： Mehmet C. Oz , Gerald M. Lemole , Alan Lotvin , Juan P. Umana , William Allen , Howard R. Levin
发明人： Mehmet C. Oz , Gerald M. Lemole , Alan Lotvin , Juan P. Umana , William Allen , Howard R. Levin
IPC分类号： A61B17/10 , A61B17/08
CPC分类号： A61B17/0686 , A61B17/064 , A61B17/0644 , A61B17/08 , A61B17/10 , A61B17/122 , A61B17/1285 , A61B2017/00243 , A61B2017/0649 , A61F2/2427
摘要： An apparatus for the repair of a cardiovascular valve has leaflets comprising a grasper capable of grabbing and co-apting the leaflets of the valve. In a preferred embodiment, the grasper has jaws that grasp and immobilize the leaflets, and then a fastener is inserted to co-apt the leaflets. The apparatus is particularly useful for repairing mitral valves to cure mitral regurgitation.
摘要翻译：用于修复心血管瓣膜的装置具有包括能够抓住和共同锁定瓣膜的小叶片的抓紧器的小叶。在优选实施例中，抓紧器具有抓住和固定传单的钳口，然后将紧固件插入以与传单共同适配。该装置特别适用于修复二尖瓣以治愈二尖瓣反流。

9. 发明授权

US07959583B2 Integrated lancet and bodily fluid sensor 有权
标题翻译：集成的柳叶刀和体液传感器
公开(公告)号：US07959583B2
公开(公告)日：2011-06-14
申请号：US11704186
申请日：2007-02-09
申请人： John D. DeNuzzio , Steven Keith , Lawrence A. Monahan , Phyllis Palmer , Bill Stewart , Todd M. Chelak , Robert E. West , William Allen , Frederick Karl , Lee Griswold
发明人： John D. DeNuzzio , Steven Keith , Lawrence A. Monahan , Phyllis Palmer , Bill Stewart , Todd M. Chelak , Robert E. West , William Allen , Frederick Karl , Lee Griswold
IPC分类号： A61B5/00
CPC分类号： A61B5/1486 , A61B5/150022 , A61B5/150305 , A61B5/150358 , A61B5/150412 , A61B5/150503 , A61B5/150618 , A61B5/150725 , A61B5/15107 , A61B5/15117 , A61B5/1519 , A61B5/15194 , A61B2562/0295 , Y10T29/49002 , Y10T29/49826
摘要： A lancing device integrated with a sensing strip and method of making and using the same are provided. A lance and analyte sensing strip are combined in a single, preferably disposable, device. In a preferred embodiment, a slot is provided in a support member so the lance can be engaged by a lance driver and driven into the skin producing a bodily fluid sample from a wound. The sensing area of the sensing strip is adjacent to the wound location reducing dexterity requirements for patients.
摘要翻译：提供了与传感带集成的穿刺装置及其制造和使用方法。喷枪和分析物感测带组合在单个，优选一次性的装置中。在优选实施例中，在支撑构件中设置狭槽，使得喷枪可以由喷枪驱动器接合并被驱动到皮肤中，从伤口产生体液样品。传感带的传感区域与伤口位置相邻，可减少对患者的灵活性要求。

10. 发明授权

US07808446B2 Active display system and method with optical addressing 失效
标题翻译：主动显示系统和光寻址方法
公开(公告)号：US07808446B2
公开(公告)日：2010-10-05
申请号：US11495353
申请日：2006-07-27
申请人： John Da Cunha , William Allen
发明人： John Da Cunha , William Allen
IPC分类号： G09G5/00
CPC分类号： G09G3/2088 , G06F3/1446 , G09G3/002 , G09G3/2014 , G09G2360/141
摘要： A display system, including an optical transmitter configured to optically transmit digital image information associated with an image to be displayed. The system also includes an active display including a decoder electrically coupled with a plurality of display elements that are configured to produce visible light in response to electrical stimulation. The decoder is configured to receive the digital image information and in response produce a control signal for each of the display elements, the control signals being usable to individually control visible light produced by the display elements so as to cause display of the image.
摘要翻译：一种显示系统，包括被配置为光学地发送与要显示的图像相关联的数字图像信息的光发送器。该系统还包括有源显示器，其包括与多个显示元件电耦合的解码器，其被配置为响应于电刺激产生可见光。解码器被配置为接收数字图像信息，并且响应于每个显示元件产生控制信号，所述控制信号可用于单独地控制由显示元件产生的可见光，以引起图像的显示。

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