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1. 发明申请

US20120011705A1 Integrated lancet and bodily fluid sensor 有权
标题翻译：集成的柳叶刀和体液传感器
公开(公告)号：US20120011705A1
公开(公告)日：2012-01-19
申请号：US12929261
申请日：2011-01-11
申请人： John D. DeNuzzio , Steven Keith , Lawrence A. Monahan , Phyllis Palmer , Bill Stewart , Todd M. Chelak , Robert E. West , William Allen , Frederick Karl , Lee Griswold
发明人： John D. DeNuzzio , Steven Keith , Lawrence A. Monahan , Phyllis Palmer , Bill Stewart , Todd M. Chelak , Robert E. West , William Allen , Frederick Karl , Lee Griswold
IPC分类号： H05K13/00 , B23P11/00
CPC分类号： A61B5/1486 , A61B5/150022 , A61B5/150305 , A61B5/150358 , A61B5/150412 , A61B5/150503 , A61B5/150618 , A61B5/150725 , A61B5/15107 , A61B5/15117 , A61B5/1519 , A61B5/15194 , A61B2562/0295 , Y10T29/49002 , Y10T29/49826
摘要： A lancing device integrated with a sensing strip and method of making and using the same are provided. A lance and analyte sensing strip are combined in a single, preferably disposable, device. In a preferred embodiment, a slot is provided in a support member so the lance can be engaged by a lance driver and driven into the skin producing a bodily fluid sample from a wound. The sensing area of the sensing strip is adjacent to the wound location reducing dexterity requirements for patients.
摘要翻译：提供了与传感带集成的穿刺装置及其制造和使用方法。喷枪和分析物感测带组合在单个，优选一次性的装置中。在优选实施例中，在支撑构件中设置狭槽，使得喷枪可以由喷枪驱动器接合并被驱动到皮肤中，从伤口产生体液样品。传感带的传感区域与伤口位置相邻，可减少对患者的灵活性要求。

2. 发明授权

US08808321B2 Integrated lancet and bodily fluid sensor 有权
标题翻译：集成的柳叶刀和体液传感器
公开(公告)号：US08808321B2
公开(公告)日：2014-08-19
申请号：US12929261
申请日：2011-01-11
申请人： John D. DeNuzzio , Steven Keith , Lawrence A. Monahan , Phyllis Palmer , Bill Stewart , Todd M. Chelak , Robert E. West , William Allen , Frederick Karl , Lee Griswold
发明人： John D. DeNuzzio , Steven Keith , Lawrence A. Monahan , Phyllis Palmer , Bill Stewart , Todd M. Chelak , Robert E. West , William Allen , Frederick Karl , Lee Griswold
IPC分类号： A61B17/14 , A61B17/32 , A61B5/00 , B65D81/00
CPC分类号： A61B5/1486 , A61B5/150022 , A61B5/150305 , A61B5/150358 , A61B5/150412 , A61B5/150503 , A61B5/150618 , A61B5/150725 , A61B5/15107 , A61B5/15117 , A61B5/1519 , A61B5/15194 , A61B2562/0295 , Y10T29/49002 , Y10T29/49826
摘要： A lancing device integrated with a sensing strip and method of making and using the same are provided. A lance and analyte sensing strip are combined in a single, preferably disposable, device. In a preferred embodiment, a slot is provided in a support member so the lance can be engaged by a lance driver and driven into the skin producing a bodily fluid sample from a wound. The sensing area of the sensing strip is adjacent to the wound location reducing dexterity requirements for patients.
摘要翻译：提供了与传感带集成的穿刺装置及其制造和使用方法。喷枪和分析物感测带组合在单个，优选一次性的装置中。在优选实施例中，在支撑构件中设置狭槽，使得喷枪可以由喷枪驱动器接合并被驱动到皮肤中，从伤口产生体液样品。传感带的传感区域与伤口位置相邻，可减少对患者的灵活性要求。

3. 发明授权

US07959583B2 Integrated lancet and bodily fluid sensor 有权
标题翻译：集成的柳叶刀和体液传感器
公开(公告)号：US07959583B2
公开(公告)日：2011-06-14
申请号：US11704186
申请日：2007-02-09
申请人： John D. DeNuzzio , Steven Keith , Lawrence A. Monahan , Phyllis Palmer , Bill Stewart , Todd M. Chelak , Robert E. West , William Allen , Frederick Karl , Lee Griswold
发明人： John D. DeNuzzio , Steven Keith , Lawrence A. Monahan , Phyllis Palmer , Bill Stewart , Todd M. Chelak , Robert E. West , William Allen , Frederick Karl , Lee Griswold
IPC分类号： A61B5/00
CPC分类号： A61B5/1486 , A61B5/150022 , A61B5/150305 , A61B5/150358 , A61B5/150412 , A61B5/150503 , A61B5/150618 , A61B5/150725 , A61B5/15107 , A61B5/15117 , A61B5/1519 , A61B5/15194 , A61B2562/0295 , Y10T29/49002 , Y10T29/49826
摘要： A lancing device integrated with a sensing strip and method of making and using the same are provided. A lance and analyte sensing strip are combined in a single, preferably disposable, device. In a preferred embodiment, a slot is provided in a support member so the lance can be engaged by a lance driver and driven into the skin producing a bodily fluid sample from a wound. The sensing area of the sensing strip is adjacent to the wound location reducing dexterity requirements for patients.
摘要翻译：提供了与传感带集成的穿刺装置及其制造和使用方法。喷枪和分析物感测带组合在单个，优选一次性的装置中。在优选实施例中，在支撑构件中设置狭槽，使得喷枪可以由喷枪驱动器接合并被驱动到皮肤中，从伤口产生体液样品。传感带的传感区域与伤口位置相邻，可减少对患者的灵活性要求。

4. 发明授权

US07192405B2 Integrated lancet and bodily fluid sensor 有权
标题翻译：集成的柳叶刀和体液传感器
公开(公告)号：US07192405B2
公开(公告)日：2007-03-20
申请号：US10259798
申请日：2002-09-30
申请人： John D. DeNuzzio , Steven Keith , Lawrence A. Monahan , Phyllis Palmer , Bill Stewart , Todd M. Chelak , Robert E. West , William Allen , Frederick Karl , Lee Griswold
发明人： John D. DeNuzzio , Steven Keith , Lawrence A. Monahan , Phyllis Palmer , Bill Stewart , Todd M. Chelak , Robert E. West , William Allen , Frederick Karl , Lee Griswold
IPC分类号： A61B5/00
CPC分类号： A61B5/1486 , A61B5/150022 , A61B5/150305 , A61B5/150358 , A61B5/150412 , A61B5/150503 , A61B5/150618 , A61B5/150725 , A61B5/15107 , A61B5/15117 , A61B5/1519 , A61B5/15194 , A61B2562/0295 , Y10T29/49002 , Y10T29/49826
摘要： A lancing device integrated with a sensing strip and method of making and using the same are provided. A lance and analyte sensing strip are combined in a single, preferably disposable, device. In a preferred embodiment, a slot is provided in a support member so the lance can be engaged by a lance driver and driven into the skin producing a bodily fluid sample from a wound. The sensing area of the sensing strip is adjacent to the wound location reducing dexterity requirements for patients.
摘要翻译：提供了与传感带集成的穿刺装置及其制造和使用方法。喷枪和分析物感测带组合在单个，优选一次性的装置中。在优选实施例中，在支撑构件中设置狭槽，使得喷枪能够由喷枪驱动器接合并被驱动到皮肤中，从伤口产生体液样品。传感带的传感区域与伤口位置相邻，可减少对患者的灵活性要求。

5. 发明授权

US06644309B2 Medicament respiratory delivery device and method 有权
公开(公告)号：US06644309B2
公开(公告)日：2003-11-11
申请号：US09950369
申请日：2001-09-10
申请人： Robert A. Casper , John M. Snow , David L. Gardner , Vincent J. Sullivan , Anjana Bhuta Wills , Lawrence A. Monahan , Christopher J. Knors
发明人： Robert A. Casper , John M. Snow , David L. Gardner , Vincent J. Sullivan , Anjana Bhuta Wills , Lawrence A. Monahan , Christopher J. Knors
IPC分类号： A61M1500
CPC分类号： B05B11/061 , A61M11/02 , A61M15/0028 , A61M15/0031 , A61M15/0081 , A61M15/08 , A61M2202/04 , A61M2202/064 , A61M2205/073 , B05B11/062
摘要： A medicament respiratory delivery device including a housing having a chamber including coaxially aligned inlet and outlet, a medicament cartridge located within the chamber having a passage therethrough and membranes sealing the passage having a burst pressure of less than 10 atmospheres, a manually actuatable fluid delivery device having an outlet in fluid communication with the chamber and a manually actuated valve located between the outlet of the fluid delivery device and the chamber inlet for delivery of fluid under pressure to the valve. The medicament respiratory delivery device of this invention may be utilized to deliver a controlled unit dose of an aerosolizable medicament on demand by first pressurizing a pressure chamber in the pressure delivery device upstream of the valve, then opening the valve to open the membranes and express the medicament through the chamber outlet.

6. 发明申请

US20090143767A1 Catheter assemblies and injection molding processes and equipment for making the same 审中-公开
标题翻译：导管组件和注射成型工艺以及制造相同的设备
公开(公告)号：US20090143767A1
公开(公告)日：2009-06-04
申请号：US12290448
申请日：2008-10-30
申请人： James Fentress , Scott A. O'Connor , Scott A. White , Lawrence A. Monahan , Frank E. Martin , Kevin G. Tingey , Craig N. Gawreluk
发明人： James Fentress , Scott A. O'Connor , Scott A. White , Lawrence A. Monahan , Frank E. Martin , Kevin G. Tingey , Craig N. Gawreluk
IPC分类号： A61M25/00 , B28B5/00
CPC分类号： A61M25/0009 , A61M25/0014 , B29C45/0001 , B29C45/0003 , B29C45/16 , B29C45/261 , B29C45/2708 , B29K2075/00 , B29L2031/7542
摘要： Various single-part catheter assemblies, multi-part integrated catheter assemblies, and methods for making the same are disclosed. The single-part catheter assemblies include a catheter hub integrally formed with a catheter tube for insertion into the bloodstream of a patient. The multi-part integrated catheter assemblies include a catheter hub integrally formed to a catheter tube for insertion into the bloodstream of a patient. The catheter assemblies of the invention may be injection molded in a single step or in multiple steps by injecting flows of molten plastic into a cavity of molds provided herein such that the flows converge into an even distribution about the circumference of the sleeve. The mold may have a core pin designed to fit into the cavity. Through the use of the even distribution of flows, the core pin may be seated within the cavity in an untensioned manner. The catheter assemblies of the invention may be produced of a single material or of multiple materials.
摘要翻译：公开了各种单一部件导管组件，多部分集成导管组件及其制造方法。单组件导管组件包括与用于插入患者血流中的导管管一体形成的导管座。多部分集成导管组件包括与导管管一体形成的用于插入患者血流的导管套管。本发明的导管组件可以在单个步骤或多个步骤中通过将熔融塑料流注入本文提供的模具的空腔中而注射模制，使得流体围绕套筒的圆周收敛成均匀分布。模具可以具有设计成适合于空腔的芯销。通过使用均匀的流动分布，芯销可以以未张紧的方式安置在空腔内。本发明的导管组件可以由单一材料或多种材料制成。

7. 发明申请

US20120245558A1 SELF-INJECTION DEVICE 有权
标题翻译：自动注射装置
公开(公告)号：US20120245558A1
公开(公告)日：2012-09-27
申请号：US13261212
申请日：2009-09-15
申请人： David T. Durack , Artis R. Lockhart , Lawrence A. Monahan
发明人： David T. Durack , Artis R. Lockhart , Lawrence A. Monahan
IPC分类号： A61M5/46 , A61M5/31 , A61M5/32
CPC分类号： A61M5/326 , A61M5/282 , A61M5/3287 , A61M5/46 , A61M2005/3247 , A61M2005/3267
摘要： A self-injection device (101) for delivering a medicament includes a housing (111), and a needle (103) connected to the housing (111). A compressible reservoir (121) is connected to the housing (111) and is in fluid communication with a needle (103) such that compressing the reservoir (121) delivers medicament from the reservoir (121) to the needle (103) and moves the needle (103) from the first position to the second position. A platform (171) is disposed within the housing (111) about which the housing (111) is rotatable between a plurality of positions. Each of the positions corresponds to a different distance the needle (103) is moved to the second position during an injection to provide a variable injection depth. The needle (103) is withdrawn into the housing (111) after an injection without requiring manual manipulation by the user, thereby preventing needle sticks and other accidents.
摘要翻译：用于输送药物的自动注射装置（101）包括壳体（111）和连接到壳体（111）的针（103）。可压缩储存器（121）连接到壳体（111）并与针（103）流体连通，使得压缩储存器（121）将药物从储存器（121）输送到针（103）并将针（103）从第一位置到第二位置。平台（171）设置在壳体（111）内，壳体（111）可在多个位置之间旋转。每个位置对应于在注射期间针（103）移动到第二位置的不同距离以提供可变的喷射深度。针（103）在注射后被抽出到壳体（111）中，而不需要用户的手动操纵，从而防止针刺等事故。

8. 发明授权

US07051734B2 Medicament respiratory delivery device and method 有权
公开(公告)号：US07051734B2
公开(公告)日：2006-05-30
申请号：US10685187
申请日：2003-10-14
申请人： Robert A. Casper , John M. Snow , David L. Gardner , Vincent J. Sullivan , Anjana Bhuta Wills , Lawrence A. Monahan , Christopher J. Knors
发明人： Robert A. Casper , John M. Snow , David L. Gardner , Vincent J. Sullivan , Anjana Bhuta Wills , Lawrence A. Monahan , Christopher J. Knors
IPC分类号： A61M15/00 , A61M16/00 , A61M15/08
CPC分类号： B05B11/061 , A61M11/02 , A61M15/0028 , A61M15/0031 , A61M15/0081 , A61M15/08 , A61M2202/04 , A61M2202/064 , A61M2205/073 , B05B11/062
摘要： A medicament respiratory delivery device including a housing having a chamber including coaxially aligned inlet and outlet, a medicament cartridge located within the chamber having a passage therethrough and membranes sealing the passage having a burst pressure of less than 10 atmospheres, a manually actuatable fluid delivery device having an outlet in fluid communication with the chamber and a manually actuated valve located between the outlet of the fluid delivery device and the chamber inlet for delivery of fluid under pressure to the valve. The medicament respiratory delivery device of this invention may be utilized to deliver a controlled unit dose of an aerosolizable medicament on demand by first pressurizing a pressure chamber in the pressure delivery device upstream of the valve, then opening the valve to open the membranes and express the medicament through the chamber outlet.

9. 发明授权

US08369916B2 Optical fiber connector 有权
标题翻译：光纤连接器
公开(公告)号：US08369916B2
公开(公告)日：2013-02-05
申请号：US12527999
申请日：2008-02-25
申请人： Ross W. Jacobson , Alexander G. Lastovich , Lawrence A. Monahan , Edward P. Browka
发明人： Ross W. Jacobson , Alexander G. Lastovich , Lawrence A. Monahan , Edward P. Browka
IPC分类号： A61B5/00
CPC分类号： A61B5/14546 , A61B5/0084 , A61B5/150022 , A61B5/150389 , A61B5/150435 , A61B5/150519 , A61B5/150809 , A61B5/150816 , A61B5/150969 , A61B5/15105 , A61B5/15142 , A61B5/155 , A61B5/6848 , G02B6/3624
摘要： An optical connector device is disclosed for optically connecting a biosensor wearable on the body of a patient to a reader outside of the body of the patient. The device comprises a base disk to be worn on the body of a patient. The base disk has a needle attached thereto and the needle houses a first fiber defining a first optical conduit. The distal end of the needle is insertable into the body of the patient, and a portion of the proximal end of the needle remains outside of the body of the patient when the device is worn. The device also comprises a connector housing a second fiber defining a second optical conduit.
摘要翻译：公开了一种光学连接器装置，用于将可佩戴在患者身体上的生物传感器光学连接到患者体外的读取器。该装置包括要戴在患者身上的基盘。基盘具有附接到其上的针，并且针容纳限定第一光导管的第一光纤。针的远端可插入患者的身体，并且当穿戴该装置时，针的近端的一部分保持在患者体内的外部。该装置还包括容纳限定第二光导管的第二光纤的连接器。

10. 发明授权

US06929005B2 Medicament respiratory delivery device, cartridge and method of making same 有权
标题翻译：药物呼吸装置，药筒及其制造方法
公开(公告)号：US06929005B2
公开(公告)日：2005-08-16
申请号：US09879517
申请日：2001-06-12
申请人： Vincent J. Sullivan , Anjana Bhuta Wills , Lawrence A. Monahan , Michael W. Trull , Christopher J. Knors
发明人： Vincent J. Sullivan , Anjana Bhuta Wills , Lawrence A. Monahan , Michael W. Trull , Christopher J. Knors
IPC分类号： A61J1/06 , A61J7/00 , A61M11/06 , A61M15/00 , B05B11/06
CPC分类号： A61M15/0028 , A61M11/002 , A61M11/003 , A61M11/02 , A61M15/0025 , A61M15/0031 , A61M15/0033 , A61M15/004 , A61M15/0041 , A61M15/0068 , A61M2202/064 , A61M2205/075 , A61M2207/00 , B05B11/061 , B05B11/062
摘要： A medicament respiratory delivery device including a housing having a chamber, an inlet and an outlet generally coaxially aligned with the chamber, wherein the chamber includes a medicament cartridge having a body including a generally cylindrical passage extending through the opposed ends of the cartridge generally coaxially aligned with the inlet and outlet of the housing having thin burstable polyolefin membranes having a burst pressure of between 1.2 and 10 atmospheres stretched taut over the ends of the cartridge, such that fluid delivered to the inlet ruptures the membranes, entraining medicament contained within the cartridge passage which is delivered to the patient's respiratory system through the outlet. The method of forming the cartridge includes stretching out and bending a membrane to one end of the cartridge, preferably by heat bonding, filling the cartridge with a medicament and sealing the opposed end preferably with a second burstable membrane by stretching out a membrane over a convex surface and heat bonding.
摘要翻译：一种药物呼吸递送装置，包括具有腔室，大体上与腔室同轴对准的入口和出口的壳体，其中所述腔室包括药剂盒，所述药剂盒具有主体，该主体包括大体上圆柱形的通道，该通道延伸穿过所述药筒的相对端，壳体的入口和出口具有薄的可爆破的聚烯烃膜，其具有介于盒的端部之间拉伸的介于1.2和10个大气压之间的爆破压力，使得输送到入口的流体破裂膜，夹带在盒通道内的药剂通过出口将其输送到患者的呼吸系统。形成盒的方法包括：将膜延伸出并弯曲到盒的一端，优选通过热粘合，用药物填充盒，并优选用第二可爆膜密封相对端，通过在凸起表面和热粘合。

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