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1. 发明授权

US06340360B1 System for cell growth 失效
标题翻译：细胞生长系统
公开(公告)号：US06340360B1
公开(公告)日：2002-01-22
申请号：US09170574
申请日：1998-10-13
申请人： Mark B. Lyles , Charles A. McLaughlin , Glenn A. Halff , William A. Mallow
发明人： Mark B. Lyles , Charles A. McLaughlin , Glenn A. Halff , William A. Mallow
IPC分类号： A61K922
CPC分类号： A61L27/105 , A61F2/06 , A61F2002/30062 , A61F2002/30677 , A61F2210/0004 , A61K9/0024 , A61L27/54 , A61L27/56 , A61L31/028 , A61L31/146 , A61L31/148 , A61L31/16 , A61L2300/222 , A61L2300/406 , A61L2300/43 , A61L2300/604 , A61L2300/64 , A61M31/002
摘要： An implantable infection shield and system for drug delivery in vascular tissue includes a relatively non-biodegradable porous linked fibrous biomaterial which controls and directs cell growth and angiogenesis from adjacent vascular tissue into the implant. Infection shield embodiments stimulate cell growth and angiogenesis from adjacent vascular tissue which effectively blocks passage of pathogenic microorganisms along percutaneously implanted objects. In embodiments for drug delivery, a reservoir of the same biomaterial may contain either (1) a cell culture system enclosed within a porous sealable interior chamber or (2) a biodegradable matrix in which one or more drugs are dispersed. After implantation of a reservoir of the first embodiment in an organism, cultured cells obtain food and oxygen via diffusion in tissue fluid through the porous walls of the interior chamber, while metabolic products, including drugs, diffuse away from the cell culture in an analogous manner. In a reservoir of the second embodiment, a biodegradable matrix substantially fills the pores (voids), and progressive dissolution of the matrix releases one or more drugs into surrounding tissue fluid. Reservoirs of either embodiment comprise a plurality of voids of a predetermined size effective for stimulating angiogenesis from the surrounding vascular tissue into at least a portion of the reservoir. The reservoir thus acts to couple a source of drugs to the circulatory system of the organism.
摘要翻译：用于在血管组织中药物递送的可植入感染屏蔽和系统包括相对不可生物降解的多孔连接的纤维生物材料，其控制并引导细胞生长和血管生成从相邻血管组织进入植入物。感染屏障实施例刺激来自相邻血管组织的细胞生长和血管生成，其有效地阻止病原微生物沿着经皮植入物体的通过。在用于药物递送的实施方案中，相同生物材料的储库可以包含（1）包封在多孔可密封的内部室内的细胞培养系统或（2）其中分散有一种或多种药物的生物可降解基质。在将第一实施方案的储存器植入生物体之后，培养的细胞通过内部室的多孔壁在组织液中的扩散而获得食物和氧气，而代谢产物（包括药物）以类似的方式从细胞培养物扩散。在第二实施方案的储存器中，生物降解基质基本上填充孔（空隙），并且基质的逐渐溶解将一种或多种药物释放到周围的组织液中。任一实施方案的储库包括多个预定尺寸的空隙，其有效刺激来自周围血管组织的血管发生至储存器的至少一部分。因此，储存器用于将药物源与生物体的循环系统结合。

2. 发明授权

US5976244A Fixation of hazardous wastes and related products 失效
标题翻译：固定危险废物及相关产品
公开(公告)号：US5976244A
公开(公告)日：1999-11-02
申请号：US17584
申请日：1998-02-03
申请人： William A. Mallow
发明人： William A. Mallow
IPC分类号： A62D3/00 , A62D3/30 , A62D3/33 , A62D101/08 , A62D101/24 , A62D101/43 , C04B28/36 , B09B3/00
CPC分类号： A62D3/33 , C04B28/36 , A62D2101/08 , A62D2101/24 , A62D2101/43 , C04B2103/0067 , Y02W30/91
摘要： A method of fixation of hazardous waste materials is disclosed wherein the hazardous waste is admixed with materials capable of reacting in situ to form zeolites and the mixture subjected to conditions sufficient to form zeolites in which the hazardous material is part of the zeolite structure. The invention also relates to the resultant synthetic zeolite and to products formed by embedding the synthetic zeolites in a modified sulfur cement.
摘要翻译：公开了一种固定有害废料的方法，其中危险废物与能够原位反应形成沸石的材料混合，混合物经受足以形成沸石结构的沸石的条件。本发明还涉及所得的合成沸石和通过将合成沸石包埋在改性硫磺水泥中形成的产物。

3. 发明授权

US4992310A Fire pouch 失效
标题翻译：消防袋
公开(公告)号：US4992310A
公开(公告)日：1991-02-12
申请号：US371609
申请日：1989-06-26
申请人： Gabriel M. Gelb , William A. Mallow , Scott Stropkay
发明人： Gabriel M. Gelb , William A. Mallow , Scott Stropkay
IPC分类号： A62C3/00
CPC分类号： A62C3/00 , Y10S428/92 , Y10T428/232 , Y10T428/233 , Y10T428/238 , Y10T428/239 , Y10T428/2809 , Y10T428/2839
摘要： A fire pouch is provided for protecting flammable documents from both fire and water damage. The fire pouch includes a thin pliable water-type exterior container which houses a gelled water material to absorb thermal energy during the fire. The fire pouch further comprises a hydrated intumescent material layer which is secured to the exterior container, and both absorbs thermal energy and intumesce during a fire to produce a foam layer which provides substantially increased fire protection. The gelled water layer and the hydrated intumescent material layer form a relatively thin pliable rectangular-shaped blanket having a seam which divides the blanket into a base portion and a cover portion. The blanket unfolds by bending substantially along the seams to receive the flammable documents, and folds into its protective position such that the documents are sandwiched between the based portion and the covered portion to protect the docments during a fire.
摘要翻译：提供一个防火袋，用于保护易燃物品免遭火灾和水灾。消防袋包括一个薄柔软的水型外部容器，其容纳凝胶水材料以在火中吸收热能。消防袋还包括水合膨胀材料层，其固定到外部容器，并且在火中吸收热能和膨胀以产生提供显着增加的防火的泡沫层。凝胶化水层和水合膨胀材料层形成相对薄的柔软矩形毯，其具有将毯子分成基部和覆盖部分的接缝。通过基本沿着接缝弯曲以接收可燃性文件，并且折叠成其保护位置，使得文件夹在基部和被覆盖部分之间以在火灾期间保护文件，毯子展开。

4. 发明授权

US4828620A Calcination of calcium carbonate and blend therefor 失效
标题翻译：煅烧碳酸钙并进行混合
公开(公告)号：US4828620A
公开(公告)日：1989-05-09
申请号：US89830
申请日：1987-08-27
申请人： William A. Mallow , Jerome J. Dziuk, Jr.
发明人： William A. Mallow , Jerome J. Dziuk, Jr.
IPC分类号： C01F11/06 , C04B2/10 , C04B7/42
CPC分类号： C04B7/425 , C04B2/104 , Y02P40/42
摘要： A method for calcination of a calcium carbonate material comprising heating the calcium carbonate material to a temperature and for a time sufficient to calcine the material to the degree desired while in the presence of a catalyst; said catalyst comprising at least one fused salt having the formulaMCO.sub.3.CaCO.sub.3.CaO.H.sub.2 O.sub.x,wherein M is an alkali metal and x is 0 to 1 and formed by fusing MCO.sub.3 and CaCO.sub.3 in a molar ratio of about 1:2 to 2:1, and a blend adapted to be heated to CaO comprising a calcium carbonate material and at least one such fused salt.
摘要翻译：一种煅烧碳酸钙材料的方法，包括将碳酸钙材料加热至足以在催化剂存在下煅烧所需材料的温度和时间; 所述催化剂包含至少一种具有式MCO 3 CaCO 3·CaO·H 2 O x的熔融盐，其中M是碱金属，x是0-1，并且通过使摩尔比为约1:2至2:1熔化MCO 3和CaCO 3而形成。 1，以及适于被加热到CaO的共混物，其包含碳酸钙材料和至少一种这样的稠合盐。

5. 发明申请

US20080254080A1 Novel Uses of Calcium Hydroxide 审中-公开
标题翻译：氢氧化钙的新用途
公开(公告)号：US20080254080A1
公开(公告)日：2008-10-16
申请号：US11667089
申请日：2005-11-04
申请人： Bryan C.G. Glynson , Alis A. Yeterian , John L. Sigalos , William A. Mallow , Nancy Mallow
发明人： Bryan C.G. Glynson , Alis A. Yeterian , John L. Sigalos , William A. Mallow , Nancy Mallow
IPC分类号： A01N59/06 , A01P3/00 , A01P7/04 , A01P1/00 , A01N25/34 , C09D5/14 , C09D1/12
CPC分类号： F24F3/16 , A61L2/232 , A61L9/00 , C09D5/14 , D06M11/13 , D06M11/155 , D06M11/44 , D06M11/46 , D06M11/56 , D06M11/57 , D06M13/148 , D06M15/05 , D06M15/09 , D06M15/53 , D06M16/00 , F24F2003/1675 , F24F2003/1678
摘要： A heating ventilation and air conditioning (“HVAC”) system having bacterial spore, viral, and fungal killing activity. The HVAC system components are at least partially coated with a biocidal composition having hydrated lime, soluble binder polymer mixture and humecatant are mixed in either an organic based- or water based-solvent system that is useful for coating HVAC system components.
摘要翻译：具有细菌孢子，病毒和真菌杀伤活性的加热通风和空调（“HVAC”）系统。 HVAC系统部件至少部分地涂覆有具有熟石灰的可生物杀灭组合物，可溶性粘合剂聚合物混合物和腐殖质混合在可用于涂覆HVAC系统组分的有机基或水基溶剂体系中。

6. 发明授权

US07011698B2 Stabilized biocidal coating composition and method 失效
标题翻译：稳定的杀生物涂料组合物和方法
公开(公告)号：US07011698B2
公开(公告)日：2006-03-14
申请号：US10476732
申请日：2002-05-02
申请人： William A. Mallow
发明人： William A. Mallow
IPC分类号： C09D5/14
CPC分类号： C09D5/14 , C08K3/22 , C09D1/12 , C08L57/00 , C08L21/02
摘要： A biocidal film-forming composition, preferably a paint, is disclosed, comprising hydrated lime, alkaline potassium salt, and a non-ionic polyolefinic latex resistant to hydrated-lime induced coagulation and phase separation. Also disclosed is the method of making certain such composition wherein hydrated lime is admixed with a non-ionic polyolefinic ester latex with agitation and continuing such agitation until hydrolysis of the ester is substantially completed and rheology of the composition is stabilized and the incidence of gelation is eliminated.
摘要翻译：公开了一种杀生物成膜组合物，优选涂料，其包括熟石灰，碱性钾盐和耐水合石灰诱导的凝结和相分离的非离子聚烯烃胶乳。还公开了制备某种这样的组合物的方法，其中将熟石灰与非离子聚烯烃酯胶乳搅拌混合并继续进行搅拌，直至酯的水解基本上完成，并且组合物的流变性稳定，凝胶化的发生率为消除了

7. 发明授权

US07001371B1 Porous drug delivery system 失效
标题翻译：多药物输送系统
公开(公告)号：US07001371B1
公开(公告)日：2006-02-21
申请号：US09677962
申请日：2000-10-03
申请人： Charles A. McLaughlin , Mark B. Lyles , Glenn A. Halff , William A. Mallow
发明人： Charles A. McLaughlin , Mark B. Lyles , Glenn A. Halff , William A. Mallow
IPC分类号： A61K9/22
CPC分类号： A61K9/0024 , A61L31/146 , A61L31/16 , A61L2300/222 , A61L2300/406 , A61L2300/43 , A61L2300/64
摘要： An implantable infection shield and system for drug delivery in vascular tissue includes a relatively non-biodegradable porous linked fibrous biomaterial which controls and directs cell growth and angiogenesis from adjacent vascular tissue into the implant. Infection shield embodiments stimulate cell growth and angiogenesis from adjacent vascular tissue which effectively blocks passage of pathogenic microorganisms along percutaneously implanted objects. In embodiments for drug delivery, a reservoir of the same biomaterial may contain either (1) a cell culture system enclosed within a porous sealable interior chamber or (2) a biodegradable matrix in which one or more drugs are dispersed. After implantation of a reservoir of the first embodiment in an organism, cultured cells obtain food and oxygen via diffusion in tissue fluid through the porous walls of the interior chamber, while metabolic products, including drugs, diffuse away from the cell culture in an analogous manner. In a reservoir of the second embodiment, a biodegradable matrix substantially fills the pores (voids), and progressive dissolution of the matrix releases one or more drugs into surrounding tissue fluid. Reservoirs of either embodiment comprise a plurality of voids of a predetermined size effective for stimulating angiogenesis from the surrounding vascular tissue into at least a portion of the reservoir. The reservoir thus acts to couple a source of drugs to the circulatory system of the organism.
摘要翻译：用于在血管组织中药物递送的可植入感染屏蔽和系统包括相对不可生物降解的多孔连接的纤维生物材料，其控制并引导细胞生长和血管生成从相邻血管组织进入植入物。感染屏障实施例刺激来自相邻血管组织的细胞生长和血管生成，其有效地阻止病原微生物沿着经皮植入物体的通过。在用于药物递送的实施方案中，相同生物材料的储库可以包含（1）包封在多孔可密封的内部室内的细胞培养系统或（2）其中分散有一种或多种药物的生物可降解基质。在将第一实施方案的储存器植入生物体之后，培养的细胞通过内部室的多孔壁在组织液中的扩散而获得食物和氧气，而代谢产物（包括药物）以类似的方式从细胞培养物扩散。在第二实施方案的储存器中，生物降解基质基本上填充孔（空隙），并且基质的逐渐溶解将一种或多种药物释放到周围的组织液中。任一实施方案的储库包括多个预定尺寸的空隙，其有效刺激来自周围血管组织的血管发生至储存器的至少一部分。因此，储存器用于将药物源与生物体的循环系统结合。

8. 发明授权

US5358994A Thermoplastic material for production and repair of polymeric products and coating of metals 失效
标题翻译：用于生产和修复聚合物产品和金属涂层的热塑性材料
公开(公告)号：US5358994A
公开(公告)日：1994-10-25
申请号：US938453
申请日：1992-08-31
申请人： William A. Mallow
发明人： William A. Mallow
IPC分类号： C08K5/00 , C08L23/04 , C08L23/06 , C08L23/08 , C08L23/12 , C08L23/16 , C08K3/04
CPC分类号： C08K5/005 , C08L23/06 , C08L2205/03 , C08L23/0853 , C08L23/12 , C08L23/16 , Y10S524/906
摘要： A composition of matter comprises 100-800 parts by weight polyethylenes and copolymers thereof having a melt index of 1-4 g/10 min., a density of 0.93-0.95 g/cc and a weight average molecular weight of 5-1.0.times.10.sup.5 ; 100-400 parts by weight polyethylenes having a melt index of 2-4 g/10 min., a density of 0.93-0.95 g/cc and a molecular weight of 6-20.times.10.sup.4 ; 0-100 parts by weight polypropylene having a melt index of 5-9 g/10 min. and a density of 0.8-1.2 g/cc; 0-150 parts by weight copolymer such as ethylene-propylene or ethylene-vinyl acetate; 0-100 parts by weight graphite or carbon black; 0.04-0.2 parts by weight antioxidant; and 0.1-2.0 parts by weight light stabilizer. A sealant is obtained by compression, extrusion or injection molding the composition described above. A polyethylene surface repair or reinforcing kit comprises the sealant or thermoplastic repair material of the invention, a thin, heat-resistant, adhesion-resistant barrier, and a polyethylene surface enzyme cleaner. A method of repairing or reinforcing a polyethylene surface comprises applying over an area of the surface in need of repair or reinforcement the sealant or thermoplastic repair material of the invention, heating the area of contact between the sealant and the surface to produce thermal fusion therebetween, and cooling the fused surface. A method of preparing a thermoplastic polyethylene surface sealant or thermoplastic repair product comprises blending the composition of the invention, and compression, injection or extrusion molding the blend to form a product of a desired shape.
摘要翻译：物质组合物包含100-800重量份的聚乙烯及其共聚物，其熔体指数为1-4g / 10min，密度为0.93-0.95g / cc，重均分子量为5-1.0×10 5; 100-400重量份熔体指数为2-4g / 10分钟的聚乙烯，密度为0.93-0.95g / cc，分子量为6-20×10 4; 0-100重量份熔体指数为5-9克/ 10分钟的聚丙烯。密度为0.8-1.2g / cc; 0-150重量份共聚物如乙烯 - 丙烯或乙烯 - 乙酸乙烯酯; 0-100重量份石墨或炭黑; 0.04-0.2重量份抗氧化剂; 和0.1-2.0重量份的光稳定剂。通过压缩，挤出或注射成型上述组合物获得密封剂。聚乙烯表面修复或增强套件包括本发明的密封剂或热塑性修补材料，薄的，耐热的，耐粘合的屏障和聚乙烯表面酶清洁剂。一种修复或加固聚乙烯表面的方法包括在需要修复或加强本发明的密封剂或热塑性修复材料的表面的一个区域上施加，加热密封剂和表面之间的接触区域以在其间产生热熔融，并冷却熔融表面。制备热塑性聚乙烯表面密封剂或热塑性修补产品的方法包括将本发明的组合物和压缩，注射或挤出成型共混物混合以形成所需形状的产品。

9. 发明授权

US4424867A Heat hardening sealant-gel for flexible couplings 失效
标题翻译：用于柔性联轴器的热硬化密封胶
公开(公告)号：US4424867A
公开(公告)日：1984-01-10
申请号：US249629
申请日：1981-03-31
申请人： William A. Mallow
发明人： William A. Mallow
IPC分类号： A62C2/00 , A62C3/16 , C04B40/06 , F16L5/04 , H02G3/22 , A62C1/00
CPC分类号： F16L5/04 , C04B40/06 , H02G3/22
摘要： This specification discloses a means for providing a barrier against the passage of fire through that portion of a wall aperture surrounding an electrical conduit, pipe, or the like. This is accomplished by placing a sleeve around that portion of the conduit passing through the wall, which sleeve is the central portion of an envelope which is anchored peripherally to the wall or to a more or less rigid material blocking the aperture through the wall and which sleeve connects to end portions of the envelope, each of which end portions extends to connect with the conduit on an opposite side of the wall. The annular region between the conduit and the surrounding envelope is filled with an intumescent gel. The boot is flexible and capable of some movement to compensate for thermal expansion, vibration or other forces during the life of the installation. In the event of heat and fire, the gel within the envelope intumesces, providing protection against passage of flames and gas through the annular region surrounding the conduit, which annular region is now occupied by a fire resistant mass formed by the solidification of the gel. The intumescible gel comprises sodium silicate solution, a filler, and a hardener.
摘要翻译：本说明书公开了一种用于提供阻挡火通过围绕电导管，管等的壁孔的那部分的阻挡件的装置。这是通过将套管围绕穿过壁的导管的该部分来实现的，该套管是封套的中心部分，该外壳围绕壁被锚固，或者是或多或少的刚性材料通过壁阻挡孔，并且其中套筒连接到信封的端部，每个端部部分延伸以在壁的相对侧上与导管连接。导管和周围信封之间的环形区域填充有膨胀凝胶。靴子是灵活的，并且能够进行一些运动以补偿在安装期间的热膨胀，振动或其他力。在发生热和火的情况下，信封内的凝胶膨胀，提供防止火焰和气体通过导管周围的环形区域的保护，该环形区域现在由凝胶凝固形成的耐火材料占据。可膨胀凝胶包括硅酸钠溶液，填料和硬化剂。

10. 发明授权

US4143426A Permanently attached artificial limb 失效
标题翻译：永久连接的假肢
公开(公告)号：US4143426A
公开(公告)日：1979-03-13
申请号：US782849
申请日：1977-03-30
申请人： C. William Hall , William A. Mallow , Fred O. Hoese
发明人： C. William Hall , William A. Mallow , Fred O. Hoese
IPC分类号： A61F2/00 , A61F2/08 , A61F2/28 , A61F2/30 , A61F2/60 , A61F2/68 , A61F1/08 , A61F1/24
CPC分类号： A61F2/0811 , A61F2/08 , A61F2/2814 , A61F2/60 , A61F2/30749 , A61F2/30767 , A61F2002/0829 , A61F2002/0864 , A61F2002/087 , A61F2002/0888 , A61F2002/307 , A61F2002/30975 , A61F2002/6872 , A61F2002/7887 , A61F2250/0081 , A61F2310/00401 , A61F2310/00574 , A61F2310/00928 , A61F2310/00952
摘要： A permanently attached artificial limb comprises an endoprosthesis in combination with an artificial tendon attachment. The artificial tendon attachment permits the use of existing skeletal muscles to power external articulating mechanical joints of the endoprosthesis device. The artificial tendon penetrates the skin and provides a strong interface with existing skeletal muscles.
摘要翻译：永久附着的假肢包括与人造肌腱附件组合的内假体。人造腱附件允许使用现有的骨骼肌来为内用假体装置的外部关节机械关节提供动力。人造肌腱穿透皮肤，并提供与现有骨骼肌强烈的界面。

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