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1. 发明申请

WO2013134087A1 CORROSION PROTECTION IN TUBING USED IN CHROMATOGRAPHY 审中-公开
标题翻译：用于色谱中的管道中的腐蚀保护
公开(公告)号：WO2013134087A1
公开(公告)日：2013-09-12
申请号：PCT/US2013/028798
申请日：2013-03-04
申请人： WATERS TECHNOLOGIES CORPORATION
发明人： JOUDREY, Kurt D. , TRUDEAU, Steven D. , KEENAN, Paul , LUONGO, Joseph A. , MCCORMICK, Daniel J. , BERTHIAUME, Eugene
IPC分类号： G01N30/02
CPC分类号： B01D15/22 , G01N30/60 , G01N30/6004 , G01N30/6026 , G01N2030/027
摘要： An apparatus for use in a liquid chromatography system includes a chromatography port and a tubing assembly having a chromatography tube coupled at one end to the chromatography port. The end of the tube has an end face covered with a corrosion-resistant material, for example, gold. The corrosion-resistant nature of the material protects the end of the tube from corrosion or erosion, which improves the quality and reliability of a seal between the end face of the tube and a sealing surface of the port. Alternatively, or in addition to covering the end face of the tube with the corrosion-resistant material, a gasket covered with or made of the corrosion-resistant material can be disposed between the end face of the tube and the port. This gasket extends the reach of the tube to facilitate bottoming out the tube within the port.
摘要翻译：用于液相色谱系统的装置包括色谱端口和管组件，该管组件具有在一端与色谱端口相连的色谱管。管的端部具有覆盖有耐腐蚀材料（例如金）的端面。材料的耐腐蚀性能保护管的端部不受腐蚀或腐蚀，这提高了管的端面和端口的密封表面之间的密封的质量和可靠性。或者，或者除了用耐腐蚀材料覆盖管的端面之外，可以在管的端面和端口之间设置由耐腐蚀材料覆盖或由其制成的垫圈。该垫圈延伸管的到达，以便于在端口内从底部出来。

2. 发明申请

WO2013090147A2 HYBRID GRADIENT DELIVERY SYSTEM AND OPERATION 审中-公开
标题翻译：混合梯度交付系统和操作
公开(公告)号：WO2013090147A2
公开(公告)日：2013-06-20
申请号：PCT/US2012/068520
申请日：2012-12-07
申请人： WATERS TECHNOLOGIES CORPORATION
发明人： LUONGO, Joseph A. , DOBBS, Craig Hamilton
IPC分类号： G01N30/26
CPC分类号： B01D15/14 , B01D15/166 , G01N30/20 , G01N30/34 , G01N30/38 , Y10T137/0363 , Y10T137/85986
摘要： A liquid chromatography system includes a gradient proportioning valve in fluidic communication with sources of solvent. From the solvent sources, the gradient proportioning valve produces a low-pressure gradient stream. A first pump is in fluidic communication with the gradient proportioning valve to receive, pressurize, and move the pressurized low-pressure gradient stream to a flow-combining device. A second pump operates in parallel with the first pump and moves a pressurized solvent stream to the flow-combining device where the pressurized solvent stream combines with the low-pressure gradient stream to produce a high-pressure gradient stream. A second gradient proportioning valve can produce, from a second plurality of sources of solvent, a second low-pressure gradient stream, wherein the solvent stream moved by the second pump to the flow-combining device and combined with the other low-pressure gradient stream comprises the second low-pressure gradient stream.
摘要翻译：液相色谱系统包括与溶剂源流体连通的梯度比例阀。从溶剂来源，梯度比例阀产生低压梯度流。第一泵与梯度比例阀流体连通，以将加压的低压梯度流接收，加压并移动到流动组合装置。第二泵与第一泵平行操作并将加压溶剂流移动到流动组合装置，其中加压溶剂流与低压梯度流结合以产生高压梯度流。第二梯度比例阀可以从第二多个溶剂源产生第二低压梯度流，其中溶剂流由第二泵移动到流动组合装置并与其它低压梯度流包括第二低压梯度流。

3. 发明申请

WO2014099777A1 FLUIDIC COUPLING SEAL 审中-公开
标题翻译：流体接头密封
公开(公告)号：WO2014099777A1
公开(公告)日：2014-06-26
申请号：PCT/US2013/075383
申请日：2013-12-16
申请人： WATERS TECHNOLOGIES CORPORATION
发明人： CORMIER, Sylvain , SHREVE, Joshua A. , LUONGO, Joseph A. , KEENAN, Paul , PLANT, Kenneth
IPC分类号： F16L19/02
CPC分类号： F16L19/0212 , F16L19/0206 , G01N30/22 , G01N30/6026
摘要： Described is a coupling seal that includes a polymeric body having a bore extending from a first end to an internal sealing surface and a fluid channel extending from the internal sealing surface to a second end. The bore is configured to receive a tube having a fluid channel so that an endface of the tube engages the internal sealing surface. The second end of the polymeric body is configured to contact a sealing surface of a coupling body that has a fluid channel extending from the sealing surface. A fluidic seal occurs when the coupling seal is compressed between the endface and the sealing surface. A void between an outer surface of the polymeric body and an inner surface of the coupling body receives the deformation of the coupling seal while under compression to thereby prevent the fluid channel of the tube from being crushed or obstructed.
摘要翻译：描述了一种联接密封件，其包括具有从第一端延伸到内部密封表面的孔的聚合物主体和从内部密封表面延伸到第二端的流体通道。孔构造成接收具有流体通道的管，使得管的端面与内部密封表面接合。聚合物体的第二端构造成接触具有从密封表面延伸的流体通道的联接体的密封表面。当连接密封件在端面和密封表面之间被压缩时，发生流体密封。聚合物主体的外表面和联接体的内表面之间的空隙在压缩时接合联接密封件的变形，从而防止管的流体通道被压碎或阻塞。

4. 发明申请

WO2012148726A1 HIGH PRESSURE PUMP WITH REDUCED SEAL WEAR 审中-公开
标题翻译：具有减少密封磨损的高压泵
公开(公告)号：WO2012148726A1
公开(公告)日：2012-11-01
申请号：PCT/US2012/033868
申请日：2012-04-17
申请人： WATERS TECHNOLOGIES CORPORATION , SHREVE, Joshua A. , ALMEIDA, Neal B. , ANGELOSANTO, John , LUONGO, Joseph A.
发明人： SHREVE, Joshua A. , ALMEIDA, Neal B. , ANGELOSANTO, John , LUONGO, Joseph A.
IPC分类号： F04B17/00
CPC分类号： F04B7/0088 , F04B15/00 , F04B53/007 , F04B53/02 , F04B53/164
摘要： Described are embodiments of a pump that can be used, for example, in liquid chromatography applications. The pump includes a seal wash housing, pump head and seal assembly. A wear-resistant coating applied to a sealing surface or gland of the pump head or seal wash housing improves the hardness and chemical compatibility of the sealing surface. Oxidation of the sealing surface is reduced so that the sealing surface is less abrasive to the seal assembly and the lifetime of the seal assembly is increased.
摘要翻译：描述了可以用于例如液相色谱应用中的泵的实施方案。该泵包括一个密封清洗外壳，泵头和密封组件。施加到泵头或密封清洗壳体的密封表面或密封套上的耐磨涂层改善了密封表面的硬度和化学相容性。减小密封表面的氧化，使得密封表面对密封组件的磨损较小，并且密封组件的寿命增加。

5. 发明授权

EP2702271B1 HIGH PRESSURE PUMP WITH REDUCED SEAL WEAR 有权
公开(公告)号：EP2702271B1
公开(公告)日：2020-02-12
申请号：EP12777825.6
申请日：2012-04-17
申请人： Waters Technologies Corporation
发明人： SHREVE, Joshua A. , ALMEIDA, Neal B. , ANGELOSANTO, John , LUONGO, Joseph A.
IPC分类号： F04B15/00 , F04B53/00 , F04B53/02 , F04B53/16

6. 发明公开

EP2935962A1 FLUIDIC COUPLING SEAL 有权
标题翻译： SEAL用于流体离合器
公开(公告)号：EP2935962A1
公开(公告)日：2015-10-28
申请号：EP13864021.4
申请日：2013-12-16
申请人： Waters Technologies Corporation
发明人： CORMIER, Sylvain , SHREVE, Joshua A. , LUONGO, Joseph A. , KEENAN, Paul , PLANT, Kenneth
IPC分类号： F16L19/02
摘要： Described is a coupling seal that includes a polymeric body having a bore extending from a first end to an internal sealing surface and a fluid channel extending from the internal sealing surface to a second end. The bore is configured to receive a tube having a fluid channel so that an endface of the tube engages the internal sealing surface. The second end of the polymeric body is configured to contact a sealing surface of a coupling body that has a fluid channel extending from the sealing surface. A fluidic seal occurs when the coupling seal is compressed between the endface and the sealing surface. A void between an outer surface of the polymeric body and an inner surface of the coupling body receives the deformation of the coupling seal while under compression to thereby prevent the fluid channel of the tube from being crushed or obstructed.

7. 发明公开

EP4390389A2 HYBRID GRADIENT DELIVERY SYSTEM AND OPERATION 审中-实审
公开(公告)号：EP4390389A2
公开(公告)日：2024-06-26
申请号：EP24167185.8
申请日：2012-12-07
申请人： Waters Technologies Corporation
发明人： LUONGO, Joseph A. , DOBBS, Craig Hamilton
IPC分类号： G01N30/38
CPC分类号： G01N30/34 , B01D15/166 , G01N30/20 , G01N30/38 , Y10T137/0363 , Y10T137/85986
摘要： A liquid chromatography system includes a gradient proportioning valve in fluidic communication with sources of solvent. From the solvent sources, the gradient proportioning valve produces a low-pressure gradient stream. A first pump is in fluidic communication with the gradient proportioning valve to receive, pressurize, and move the pressurized low-pressure gradient stream to a flow-combining device. A second pump operates in parallel with the first pump and moves a pressurized solvent stream to the flow-combining device where the pressurized solvent stream combines with the low-pressure gradient stream to produce a high-pressure gradient stream. A second gradient proportioning valve can produce, from a second plurality of sources of solvent, a second low-pressure gradient stream, wherein the solvent stream moved by the second pump to the flow-combining device and combined with the other low-pressure gradient stream comprises the second low-pressure gradient stream.

8. 发明授权

EP2935962B1 FLUIDIC COUPLING SEAL 有权
公开(公告)号：EP2935962B1
公开(公告)日：2020-10-07
申请号：EP13864021.4
申请日：2013-12-16
申请人： Waters Technologies Corporation
发明人： CORMIER, Sylvain , SHREVE, Joshua A. , LUONGO, Joseph A. , KEENAN, Paul , PLANT, Kenneth
IPC分类号： G01N30/60 , F16L19/02 , G01N30/22

9. 发明公开

EP2702271A1 HIGH PRESSURE PUMP WITH REDUCED SEAL WEAR 有权
标题翻译：与减少磨损密封高压泵
公开(公告)号：EP2702271A1
公开(公告)日：2014-03-05
申请号：EP12777825.6
申请日：2012-04-17
申请人： Waters Technologies Corporation
发明人： SHREVE, Joshua A. , ALMEIDA, Neal B. , ANGELOSANTO, John , LUONGO, Joseph A.
IPC分类号： F04B17/00
CPC分类号： F04B7/0088 , F04B15/00 , F04B53/007 , F04B53/02 , F04B53/164
摘要： Described are embodiments of a pump that can be used, for example, in liquid chromatography applications. The pump includes a seal wash housing, pump head and seal assembly. A wear-resistant coating applied to a sealing surface or gland of the pump head or seal wash housing improves the hardness and chemical compatibility of the sealing surface. Oxidation of the sealing surface is reduced so that the sealing surface is less abrasive to the seal assembly and the lifetime of the seal assembly is increased.

10. 发明公开

EP4390389A3 HYBRID GRADIENT DELIVERY SYSTEM AND OPERATION 审中-实审
公开(公告)号：EP4390389A3
公开(公告)日：2024-09-18
申请号：EP24167185.8
申请日：2012-12-07
申请人： Waters Technologies Corporation
发明人： LUONGO, Joseph A. , DOBBS, Craig Hamilton
IPC分类号： G01N30/34 , G01N30/26 , B01D15/16 , G01N30/32 , G01N30/20
CPC分类号： G01N30/34 , B01D15/166 , G01N30/20 , G01N30/38 , Y10T137/0363 , Y10T137/85986 , G01N30/32
摘要： A liquid chromatography system includes a gradient proportioning valve in fluidic communication with sources of solvent. From the solvent sources, the gradient proportioning valve produces a low-pressure gradient stream. A first pump is in fluidic communication with the gradient proportioning valve to receive, pressurize, and move the pressurized low-pressure gradient stream to a flow-combining device. A second pump operates in parallel with the first pump and moves a pressurized solvent stream to the flow-combining device where the pressurized solvent stream combines with the low-pressure gradient stream to produce a high-pressure gradient stream. A second gradient proportioning valve can produce, from a second plurality of sources of solvent, a second low-pressure gradient stream, wherein the solvent stream moved by the second pump to the flow-combining device and combined with the other low-pressure gradient stream comprises the second low-pressure gradient stream.

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