专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明专利

PE20091943A1 COMPUESTOS TRIAZINA COMO INHIBIDORES MTOR Y QUINASA PI3 未知
公开(公告)号：PE20091943A1
公开(公告)日：2009-12-19
申请号：PE2009000724
申请日：2009-05-25
申请人： WYETH CORP
发明人： VENKATESAN ARANAPAKAM MUDUMBAI , CHEN ZECHENG , DEHNHARDT CHRISTOPH MARTIN , DOS SANTOS OSVALDO , DELOS SANTOS EFREN GUILLERMO , ZASK ARIE , VERHEIJEN JEROEN CUNERA , KAPLAN JOSHUA AARON , RICHARD DAVID JAMES , AYRAL-KALOUSTIAN SEMIRAMIS , MANSOUR TAREK SUHAYL , GOPALSAMY ARIAMALA JAY , CURRAN KEVIN JOSEPH , SHI MENGXIAO
IPC分类号： A61K31/53 , A61P35/00 , C07D498/08
摘要： SE REFIERE A COMPUESTOS DERIVADOS DE [1,3,5]TRIAZINA 2,4,6-SUSTITUIDOS DE FORMULA (I) DONDE R1 ES (a) O (b), EN DONDE R6, R7, R8 Y R9 SON CADA UNO H, ALQUILO(C1-C6) OPCIONALMENTE SUSTITUIDO CON ALQUENILO(C2-C6), ALCADIENILO(C4-C6), ALQUINILO(C2-C6), ENTRE OTROS; LA LINEA ---- ES UN SEGUNDO ENLACE OPCIONAL; R2 ES ARILO(C6-C14)-NH-COR3, HETEROARILO(C6-C9)-NH-COR3, -CH=CH-ARILO(C6-C10)-NH-COR3, ENTRE OTROS, DONDE R3 ES OR5, NR5R5 O NHR5; R5 ES ALQUILO(C1-C6), ALQUENILO(C3-C6), ALQUINILO(C3-C6), ENTRE OTROS; R4 ES -O-ALQUILO(C1-C8), -O-ALQUENILO(C3-C8), -O-ALQUINILO(C3-C8), ENTRE OTROS. SON COMPUESTOS PREFERIDOS: 1-[4-(4,6-DIMORFOLIN-4-IL-1,3,5-TRIAZIN-2-IL)FENIL]-3-PIRIDIN-4-ILUREA, 1-[4-(4,6-DIMORFOLIN-4-IL-1,3,5-TRIAZIN-2-IL)FENIL]-3-TIOFEN-2-ILUREA, 1-[4-(4,6-DIMORFOLIN-4-IL-1,3,5-TRIAZIN-2-IL)FENIL]-3-(4-METILFENIL)UREA, ENTRE OTROS. SE REFIERE TAMBIEN A UNA COMPOSICION FARMACEUTICA Y A UN PROCEDIMIENTO DE PREPARACION. DICHOS COMPUESTOS SON INHIBIDORES DE LA FOSFATIDILINOSITOL-3 QUINASA (PI3K) Y mTOR SIENDO UTILES PARA EL TRATAMIENTO DE ATEROSCLEROSIS, RETINOPATIA DIABETICA, HIPERTROFIA PROSTATICA BENIGNA, PANCREATITIS

2. 发明专利

ES2221470T3 INHIBIDORES DE VIRUS HERPES DERIVADOS DE ALFA-METILBENCIL-TIOUREA QUE CONTIENEN UN GRUPO FENILENODIAMINA. 未知
公开(公告)号：ES2221470T3
公开(公告)日：2004-12-16
申请号：ES99963022
申请日：1999-12-06
申请人： WYETH CORP
发明人： BLOOM JONATHAN DAVID , CURRAN KEVIN JOSEPH , DIGRANDI MARTIN JOSEPH , DUSHIN RUSSELL GEORGE , LANG STANLEY ALBERT , NORTON EMILY BOUCHER
IPC分类号： A61K31/17 , A61K31/18 , A61K31/343 , A61K31/47 , A61K31/472 , A61K31/4725 , A61P31/22 , C07C335/20 , C07D215/48 , C07D215/50 , C07D215/54 , C07D217/06 , C07D217/26 , C07D307/79 , C07D307/81 , C07D307/85 , C07D405/12 , C07D407/12 , C07D335/20 , C07D285/06 , C07D307/68
摘要： Compuesto que presenta la **fórmula** en el que R1-R5 se seleccionan independientemente a partir de hidrógeno, alquilo de 1 a 6 átomos de carbono, alquenilo de 2 a 6 átomos de carbono, alquinilo de 2 a 6 átomos de carbono, perhaloalquilo de 1 a 6 átomos de carbono, cicloalquilo de 3 a 10 átomos de carbono, heterocicloalquilo de 3 a 10 miembros, arilo, heteroarilo, halógeno, -CN, -NO2, -CO2R6, -COR6, -OR6, -SR6, -SOR6, -SO2R6, -CONR7R8, -NR6N(R7R8), -N(R7R8) o -W-Y- (CH2)n-Z, con la salvedad de que por lo menos uno de R1-R5 no es hidrógeno ; o R2 y R3 o R3 y R4, forman juntos un heterocicloalquilo de 3 a 7 miembros o heteroarilo de 3 a 7 miembros; R6 y R7 son, independientemente, hidrógeno, alquilo de 1 a 6 átomos de carbono, perhaloalquilo de 1 a 6 átomos de carbono, o arilo; R8 es hidrógeno, alquilo de 1 a 6 átomos de carbono, perhaloalquilo de 1 a 6 átomos de carbono, cicloalquilo de 3 a 10 átomos de carbono, heterocicloalquilo de 3 a 10 miembros, arilo o heteroarilo, o R7 y R8, puedenformar juntos un heterocicloalquilo de 3 a 7 miembros; W es O, NR6, o está ausente; Y es -(CO)- o -(CO2)-, o está ausente; Z es alquilo de 1 a 4 átomos de carbono, -CN, -CO2R6, - COR6, -CONR7R8, -OCOR6, -NR6COR7, -OR6, -SR6, - SOR6, -SO2R6, -N(R7R8) o fenilo; G es fenilo opcionalmente sustituido con uno o más sustituyentes seleccionados a partir de alquilo de 1 a 6 átomos de carbono, alquenilo de 2 a 6 átomos de carbono, alquinilo de 2 a 6 átomos de carbono, perhaloalquilo de 1 a 6 átomos de carbono, cicloalquilo de 3 a 10 átomos de carbono, heterocicloalquilo de 3 a 10 miembros, arilo, heteroarilo, halógeno, -CN, -NO2, -CO2R6, -COR6, -OR6, -SR6, -SOR6, -SO2R6, - CONR7R8, -NR6N(R7R8), -N(R7R8) o -W-Y-(CH2)n-Z; o G es quinolilo, isoquinolilo o benzofuranilo; o una sal farmacéutica de los mismos.

4. 发明专利

AT272052T 未知
公开(公告)号：AT272052T
公开(公告)日：2004-08-15
申请号：AT99963021
申请日：1999-12-06
申请人： WYETH CORP
发明人： BLOOM JONATHAN DAVID , CURRAN KEVIN JOSEPH , DIGRANDI MARTIN JOSEPH , DUSHIN RUSSELL GEORGE , LANG STANLEY ALBERT , NORTON EMILY BOUCHER , ROSS ADMA ANTONIA , O'HARA BRYAN MARK
IPC分类号： A61K31/17 , A61K31/343 , A61K31/472 , A61P31/22 , C07C275/42 , C07C335/18 , C07C335/20 , C07C335/22 , C07D217/26 , C07D295/088 , C07D307/81 , C07D307/85
摘要： Compounds of formula (I), wherein R1-R5 are independently selected from hydrogen, alkyl of 1 to 6 carbon atoms, alkenyl of 2 to 6 carbon atoms, alkynyl of 2 to 6 carbon atoms, perhaloalkyl of 1 to 6 carbon atoms, cycloalkyl of 3 to 10 carbon atoms, heterocycloalkyl of 3 to 10 carbon members, aryl, heteroaryl, halogen, -CN, -NO2, -CO2R6, -COR6, -OR6, -SR6, -SOR6, -SO2R6, -CONR7R8, -NR6N(R7R8), -N(R7R8) or W-Y-(CH2)n-Z provided that at least one of R1-R5 is not hydrogen; or R2 and R3 or R3 and R4, taken together form a 3 to 7 membered heterocycloalkyl or 3 to 7 membered heteroaryl; R6 and R7 are independently hydrogen, alkyl of 1 to 6 carbon atoms, perhaloalkyl of 1 to 6 carbon atoms, or aryl; R8 is hydrogen, alkyl of 1 to 6 carbon atoms, perhaloalkyl of 1 to 6 carbon atoms, cycloalkyl of 3 to 10 carbon atoms, heterocycloalkyl of 3 to 10 members, aryl or heteroaryl, or R7 and R8, taken together may form a 3 to 7 membered heterocycloalkyl; R9-R12 are independently hydrogen, alkyl of 1 to 4 carbon atoms, perhaloalkyl of 1 to 4 carbon atoms, halogen, alkoxy of 1 to 4 carbon atoms, or cyano, or R9 and R10 or R11 and R12 may be taken together to form aryl of 5 to 7 carbon atoms; provided that at least one of R9-12 is not hydrogen; W is O, NR6, or is absent; Y is -(CO)- or -(CO2)-, or is absent; Z is alkyl of 1 to 4 carbon atoms, -CN, -CO2R6, COR6, -CONR7R8, -OCOR6, -NR6COR7, -OCONR6, -OR6, -SR6, -SOR6, -SO2R6, SR6N(R7R8), -N(R7R8) or phenyl; G is aryl or fused bicyclic heteroaryl; and X is a bond, -NH, alkyl of 1 to 6 carbon atoms, alkenyl of 1 to 6 carbon atoms, alkoxy of 1 to 6 carbon atoms, thioalkyl of 1 to 6 carbon atoms, alkylamino of 1 to 6 carbon atoms, or (CH)J; J is alkyl of 1 to 6 carbon atoms, cycloalkyl of 3 to 7 carbon atoms, phenyl or benzyl; and n is an integer from 1 to 6, in the treatment of diseases associated with herpes viruses including human cytomegalovirus, herpes simplex viruses, Epstein-Barr virus, varicella-zoster virus, human herpesviruses-6 and -7, and Kaposi herpes virus.

6. 发明专利

SA2974B1 مركبات تريازين كمثبطات كيناز PI3 و MTOR 未知
公开(公告)号：SA2974B1
公开(公告)日：2012-09-26
申请号：SA109300314
申请日：2009-05-23
申请人： WYETH CORP
发明人： VENKATESAN ARANAPAKAM MUDUMBAI , CHEN ZECHENG , DEHNHARDT CHRISTOPH MARTIN , SANTOS OSVALDO DOS , SANTOS EFREN GUILLERMO DELOS , ZASK ARIE , VERHEIJEN JEROEN CUNERA , KAPLAN JOSHUA ARON , RICAHRD DAVID JAMES , AYRAL-KALOUSTIAN SEMIRAMIS , MANSOUR TAREK SHOHIEL , GOPALSAMY ARIAMALA , CURRAN KEVIN JOSEPH , SHI MENGXIAO
IPC分类号： C07D498/08 , A61K31/53
摘要： الملخص: مركباتمنالصيغة Iحيث: R1 عبارةعنأو؛وR2، R4،وR6-9 يتمتعريفهمهنا،وأملاحها (salts) المقبولةصيدلانياًوesters منها. تثبطهذهالمركبات kinase PI3 وmTOR،وقدتستخدملعلاجأمراضناشئةعن kinase PI3 وmTOR،علىسبيلالمثالمختلفالسرطانات. يتموصفطرقتحضيرواستخداممركباتهذاالاختراع. يتمأيضاوصفتركيباتمختلفةتحتويعلىمركباتهذاالاختراع.

7. 发明专利

DE69919023D1 未知
公开(公告)号：DE69919023D1
公开(公告)日：2004-09-02
申请号：DE69919023
申请日：1999-12-06
申请人： WYETH CORP
发明人： BLOOM JONATHAN DAVID , CURRAN KEVIN JOSEPH , DIGRANDI JOSEPH , DUSHIN GEORGE , LANG ALBERT , NORTON BOUCHER , ROSS ANTONIA , O'HARA MARK
IPC分类号： A61K31/17 , A61K31/343 , A61K31/472 , A61P31/22 , C07C275/42 , C07C335/18 , C07C335/20 , C07C335/22 , C07D217/26 , C07D295/088 , C07D307/81 , C07D307/85
摘要： Compounds of formula (I), wherein R1-R5 are independently selected from hydrogen, alkyl of 1 to 6 carbon atoms, alkenyl of 2 to 6 carbon atoms, alkynyl of 2 to 6 carbon atoms, perhaloalkyl of 1 to 6 carbon atoms, cycloalkyl of 3 to 10 carbon atoms, heterocycloalkyl of 3 to 10 carbon members, aryl, heteroaryl, halogen, -CN, -NO2, -CO2R6, -COR6, -OR6, -SR6, -SOR6, -SO2R6, -CONR7R8, -NR6N(R7R8), -N(R7R8) or W-Y-(CH2)n-Z provided that at least one of R1-R5 is not hydrogen; or R2 and R3 or R3 and R4, taken together form a 3 to 7 membered heterocycloalkyl or 3 to 7 membered heteroaryl; R6 and R7 are independently hydrogen, alkyl of 1 to 6 carbon atoms, perhaloalkyl of 1 to 6 carbon atoms, or aryl; R8 is hydrogen, alkyl of 1 to 6 carbon atoms, perhaloalkyl of 1 to 6 carbon atoms, cycloalkyl of 3 to 10 carbon atoms, heterocycloalkyl of 3 to 10 members, aryl or heteroaryl, or R7 and R8, taken together may form a 3 to 7 membered heterocycloalkyl; R9-R12 are independently hydrogen, alkyl of 1 to 4 carbon atoms, perhaloalkyl of 1 to 4 carbon atoms, halogen, alkoxy of 1 to 4 carbon atoms, or cyano, or R9 and R10 or R11 and R12 may be taken together to form aryl of 5 to 7 carbon atoms; provided that at least one of R9-12 is not hydrogen; W is O, NR6, or is absent; Y is -(CO)- or -(CO2)-, or is absent; Z is alkyl of 1 to 4 carbon atoms, -CN, -CO2R6, COR6, -CONR7R8, -OCOR6, -NR6COR7, -OCONR6, -OR6, -SR6, -SOR6, -SO2R6, SR6N(R7R8), -N(R7R8) or phenyl; G is aryl or fused bicyclic heteroaryl; and X is a bond, -NH, alkyl of 1 to 6 carbon atoms, alkenyl of 1 to 6 carbon atoms, alkoxy of 1 to 6 carbon atoms, thioalkyl of 1 to 6 carbon atoms, alkylamino of 1 to 6 carbon atoms, or (CH)J; J is alkyl of 1 to 6 carbon atoms, cycloalkyl of 3 to 7 carbon atoms, phenyl or benzyl; and n is an integer from 1 to 6, in the treatment of diseases associated with herpes viruses including human cytomegalovirus, herpes simplex viruses, Epstein-Barr virus, varicella-zoster virus, human herpesviruses-6 and -7, and Kaposi herpes virus.

8. 发明专利

DE69917673D1 未知
公开(公告)号：DE69917673D1
公开(公告)日：2004-07-01
申请号：DE69917673
申请日：1999-12-06
申请人： WYETH CORP
发明人： BLOOM JONATHAN DAVID , CURRAN KEVIN JOSEPH , DIGRANDI JOSEPH , DUSHIN GEORGE , LANG ALBERT , NORTON BOUCHER , ROSS ANTONIA , O'HARA MARK
IPC分类号： A61K31/17 , A61K31/18 , A61K31/343 , A61K31/47 , A61K31/472 , A61K31/4725 , A61P31/22 , C07C335/20 , C07D215/48 , C07D215/50 , C07D215/54 , C07D217/06 , C07D217/26 , C07D307/79 , C07D307/81 , C07D307/85 , C07D405/12 , C07D407/12 , C07D335/20 , C07D285/06 , C07D307/68
摘要： Compounds having formula (I) wherein R1-R5 are independently selected from hydrogen, alkyl of 1 to 6 carbon atoms, alkenyl of 2 to 6 carbon atoms, alkynyl of 2 to 6 carbon atoms, perhaloalkyl of 1 to 6 carbon atoms, cycloalkyl of 3 to 10 carbon atoms, heterocycloalkyl of 3 to 10 carbon members, aryl, heteroaryl, halogen,-CN,-NO2,-CO2R6,-COR6,-OR6,-SR6,-SOR6,-SO2R6,-CONR7R8,-NR6N(R7R8),-N(R7R8) or W-Y-(CH2)n-Z provided that at least one of R1-R5 is not hydrogen; or R2 and R3, or R3 and R4, taken together to form a 3 to 7 membered heterocycloalkyl or 3 to 7 membered heteroaryl; R6 and R7 are independently hydrogen, alkyl of 1 to 6 carbon atoms, perhaloalkyl of 1 to 6 carbon atoms, or aryl; R8 is hydrogen, alkyl of 1 to 6 carbon atoms, perhaloalkyl of 1 to 6 carbon atoms, cycloalkyl of 3 to 10 carbon atoms, heterocycloalkyl of 3 to 10 members, aryl or heteroaryl, or R7 and R8, taken together may form a 3 to 7 membered heterocycloalkyl; W is O, NR6, or is absent; Y is -(CO)- or-(CO2)-, or is absent; Z is alkyl of 1 to 4 carbon atoms,-CN,-CO2R6, COR6,-CONR7R8,-OCOR6,-NR6COR7,-OCONR6,-OR6,-SR6,-SOR6,-SO2R6, SR6N(R7R8),-N(R7R8) or phenyl; G is aryl or fused bicyclic heteroaryl; X is a bond,-NH, alkyl of 1 to 6 carbon atoms, alkenyl of 1 to 6 carbon atoms, alkoxy of 1 to 6 carbon atoms, thioalkyl of 1 to 6 carbon atoms, alkylamino of 1 to 6 carbon atoms, or (CH)J; J is alkyl of 1 to 6 carbon atoms, cycloalkyl of 3 to 7 carbon atoms, phenyl or benzyl; and n is an integer from 1 to 6; useful in the treatment of diseases associated with herpes viruses including human cytomegalovirus, herpes simplex viruses, Epstein-Barr virus, varicella-zoster virus, human herpesviruses-6 and-7, and Kaposi herpesvirus.

9. 发明专利

PE20091957A1 COMPUESTOS TRIAZINA COMO INHIBIDORES MTOR Y QUINASA PI3 未知
公开(公告)号：PE20091957A1
公开(公告)日：2009-12-30
申请号：PE2009000725
申请日：2009-05-25
申请人： WYETH CORP
发明人： VENKATESAN ARANAPAKAM MUDUMBAI , CHEN ZECHENG , DEHNHARDT CHRISTOPH MARTIN , DOS SANTOS OSVALDO , DELOS SANTOS EFREN GUILLERMO , ZASK ARIE , VERHEIJEN JEROEN CUNERA , KAPLAN JOSHUA AARON , RICHARD DAVID JAMES , AYRAL-KALOUSTIAN SEMIRAMIS , MANSOUR TAREK SUHAYL , GOPALSAMY ARIAMALA JAY , CURRAN KEVIN JOSEPH , SHI MENGXIAO
IPC分类号： A61K31/53 , A61P35/00 , C07D498/08
摘要： SE REFIERE A DERIVADOS DE [1,3,5] TRIAZINA 2,4,6-SUSTITUIDOS DE FORMULA (I) DONDE R1 ES (a) O (b), EN DONDE R6, R7, R8 Y R9 SON CADA UNO H, ALQUILO(C1-C6) OPCIONALMENTE SUSTITUIDO CON ALQUENILO(C2-C6), ALCADIENILO(C4-C6), ALQUINILO(C2-C6), ENTRE OTROS; ---- ES UN SEGUNDO ENLACE OPCIONAL; R2 ES ARILO(C6-C14) OPCIONALMENTE SUSTITUIDO CON -NH-COR3, HETEROARILO(C6-C9) OPCIONALMENTE SUSTITUIDO CON -NH-COR3, -CH=CH-ARILO(C6-C10)-NH-COR3, ENTRE OTROS, DONDE R3 ES OR5, NR5R5 O NHR5; R5 ES ALQUILO(C1-C6), ALQUENILO(C3-C6), ALQUINILO(C3-C6), ENTRE OTROS; R4 ES ALQUENILO(C3-C6), ALQUINILO(C3-C6), CICLOALQUILO(C3-C8), ENTRE OTROS. SON COMPUESTOS PREFERIDOS: 1-{4-[4-MORFOLIN-4-IL-6-(8-OXA-3-AZABICICLO[3.2.1]OCT-3-IL)-1,3,5-TRIAZIN-2-IL]FENIL}-3-FENILUREA, 1-(4-FLUOROFENIL)-3-{4-[4-MORFOLIN-4-IL-6-(8-OXA-3-AZABICICLO[3.2.1]OCT-3-IL)-1,3,5-TRIAZIN-2-IL]FENIL}UREA, 1-(4-METILFENIL)-3-{4-[4-MORFOLIN-4-IL-6-(8-OXA-3-AZABICICLO[3.2.1]OCT-3-IL)-1,3,5-TRIAZIN-2-IL]FENIL}UREA, ENTRE OTROS. SE REFIERE TAMBIEN A UN PROCEDIMIENTO DE PREPARACION Y A UNA COMPOSICION FARMACEUTICA. DICHOS COMPUESTOS SON INHIBIDORES DE LA QUINASA FOSFATIDILINOSITOL-3 (PI3) Y mTOR SIENDO UTILES EN EL TRATAMIENTO DE CANCER, RESTENOSIS, ARTRITIS, SORIASIS

10. 发明专利

PE19432009A1 COMPUESTOS TRIAZINA COMO INHIBIDORES MTOR Y QUINASA PI3 未知
公开(公告)号：PE19432009A1
公开(公告)日：2009-12-19
申请号：PE0007242009
申请日：2009-05-25
申请人： WYETH CORP
发明人： VENKATESAN ARANAPAKAM MUDUMBAI , CHEN ZECHENG , DEHNHARDT CHRISTOPH MARTIN , DOS SANTOS OSVALDO , DELOS SANTOS EFREN GUILLERMO , ZASK ARIE , VERHEIJEN JEROEN CUNERA , KAPLAN JOSHUA AARON , RICHARD DAVID JAMES , AYRAL-KALOUSTIAN SEMIRAMIS , MANSOUR TAREK SUHAYL , GOPALSAMY ARIAMALA JAY , CURRAN KEVIN JOSEPH , SHI MENGXIAO
IPC分类号： A61K31/53 , A61P35/00 , C07D498/08
CPC分类号： C07D401/12 , A61K31/5377 , A61K45/06 , C07D251/18 , C07D401/04 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/12 , C07D405/14 , C07D407/14 , C07D409/12 , C07D413/04 , C07D413/14 , C07D451/06 , C07D453/02 , C07D491/113 , C07D498/08
摘要： SE REFIERE A COMPUESTOS DERIVADOS DE [1,3,5]TRIAZINA 2,4,6-SUSTITUIDOS DE FORMULA (I) DONDE R1 ES (a) O (b), EN DONDE R6, R7, R8 Y R9 SON CADA UNO H, ALQUILO(C1-C6) OPCIONALMENTE SUSTITUIDO CON ALQUENILO(C2-C6), ALCADIENILO(C4-C6), ALQUINILO(C2-C6), ENTRE OTROS; LA LINEA ---- ES UN SEGUNDO ENLACE OPCIONAL; R2 ES ARILO(C6-C14)-NH-COR3, HETEROARILO(C6-C9)-NH-COR3, -CH=CH-ARILO(C6-C10)-NH-COR3, ENTRE OTROS, DONDE R3 ES OR5, NR5R5 O NHR5; R5 ES ALQUILO(C1-C6), ALQUENILO(C3-C6), ALQUINILO(C3-C6), ENTRE OTROS; R4 ES -O-ALQUILO(C1-C8), -O-ALQUENILO(C3-C8), -O-ALQUINILO(C3-C8), ENTRE OTROS. SON COMPUESTOS PREFERIDOS: 1-[4-(4,6-DIMORFOLIN-4-IL-1,3,5-TRIAZIN-2-IL)FENIL]-3-PIRIDIN-4-ILUREA, 1-[4-(4,6-DIMORFOLIN-4-IL-1,3,5-TRIAZIN-2-IL)FENIL]-3-TIOFEN-2-ILUREA, 1-[4-(4,6-DIMORFOLIN-4-IL-1,3,5-TRIAZIN-2-IL)FENIL]-3-(4-METILFENIL)UREA, ENTRE OTROS. SE REFIERE TAMBIEN A UNA COMPOSICION FARMACEUTICA Y A UN PROCEDIMIENTO DE PREPARACION. DICHOS COMPUESTOS SON INHIBIDORES DE LA FOSFATIDILINOSITOL-3 QUINASA (PI3K) Y mTOR SIENDO UTILES PARA EL TRATAMIENTO DE ATEROSCLEROSIS, RETINOPATIA DIABETICA, HIPERTROFIA PROSTATICA BENIGNA, PANCREATITIS

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式