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    • 2. 发明申请
    • ASYMMETRIC OPENING AND CLOSING PROSTHETIC VALVE LEAFLET
    • 不对称打开和关闭前置阀门叶片
    • WO2015085138A1
    • 2015-06-11
    • PCT/US2014/068727
    • 2014-12-05
    • W.L. GORE & ASSOCIATES, INC.
    • ARMSTRONG, Joseph, R.
    • A61F2/24
    • A61F2/2418A61F2/24A61F2/2412A61F2/2415A61F2210/0076A61F2230/0006A61F2230/0071A61F2250/0014A61F2250/0018A61F2250/0029A61F2250/0036Y10T29/49901
    • A prosthetic valve (100) comprising:a plurality of leaflets (130), each leaflet defines a leaflet first side region and a leaflet second side region opposite from the leaflet first side region, each leaflet defining a leaflet base (134) and a leaflet free edge (142) opposite from the leaflet base, each leaflet first side region is coupled with the leaflet second side region of an adjacent leaflet at a commissure (136), the leaflet base of each of the plurality of leaflets together define an orifice, at least a first portion of the leaflet first side region having a first thickness and the second side region having a second thickness, the first thickness is greater than the second thickness. These leaflets move asymmetrically in that a leaflet second side region of the leaflet initially moves toward the open position before a leaflet first side region and the leaflet first side region initially moves toward the closed position before the leaflet second side region. In the fully open position, the leaflet first side region opens less than the leaflet second side region. Asymmetric opening and final open position creates spiral flow. Controlled asymmetric movement of the leaflet reduces closing volume.
    • 一种人造瓣膜(100),包括:多个叶片(130),每个叶片限定叶片第一侧区域和与小叶第一侧区域相对的小叶第二侧区域,每个叶片限定小叶基部(134)和传单 与小叶基部相对的自由边缘(142),每个小叶第一侧区域在连续(136)处与邻近小叶的小叶第二侧区域联接,多个叶片中的每一个的叶片基底一起限定孔口, 所述小叶第一侧区域的至少第一部分具有第一厚度,并且所述第二侧部区域具有第二厚度,所述第一厚度大于所述第二厚度。 这些传单不对称地移动,因为传单的小叶第二侧区域最初在小叶第一侧区域之前朝着打开位置移动,并且小叶第一侧区域最初在小叶第二侧区域之前朝向关闭位置移动。 在完全打开位置,传单第一侧区域比小叶第二侧区域打开得少。 不对称开口和最终打开位置产生螺旋流。 小叶的控制不对称运动减小了闭合体积。