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    • 2. 发明申请
    • MAIN STAGE CATHETERIZATION INSTRUMENT
    • 主要阶段通气仪器
    • WO9915227B1
    • 1999-05-14
    • PCT/US9820165
    • 1998-09-24
    • CARDEON CORPMACOVIAK JOHN ASAMSON WILFRED J
    • MACOVIAK JOHN ASAMSON WILFRED J
    • A61B17/00A61M29/02
    • A61M25/104A61B17/00234
    • The present invention discloses a main stage catheter instrument which serves as the primary catheterization access and arterial perfusion cannula for establishing cardiopulmonary bypass with selective perfusion and differential flow management of the cardiovascular, cardioneural and corporeal sub-circulations of a patient. The main stage catheter has a catheter shaft with a first occlusion member for occluding the thoracic descending aorta and an optional second occlusion member for occluding the abdominal descending aorta. A perfusion lumen in the main stage catheter supplies oxygenated blood to the aorta through distal, medial and proximal perfusion ports. Optionally, a second stage catheter inserted through the main stage catheter may be used to occlude the ascending aorta and to deliver a cardioplegic agent to the coronary arteries. The main stage catheter is coupled to a cardiopulmonary bypass system and a venous drainage catheter to establish partial or full cardiopulmonary bypass with elective cardioplegic arrest.
    • 本发明公开了一种主级导管仪器,其用作主要导管插入和动脉灌注插管,用于建立具有患者的心血管,心脏和体液亚循环的选择性灌注和不同流量管理的体外循环。 主级导管具有导管轴,该导管杆具有用于阻塞胸降主动脉的第一阻塞构件和用于阻塞腹降主动脉的可选的第二阻塞构件。 主级导管中的灌注腔通过远端,中间和近端灌注端口向主动脉供应含氧血液。 任选地,插入穿过主级导管的第二级导管可用于阻塞升主动脉并将心脏停搏药递送至冠状动脉。 主级导管连接到体外循环系统和静脉引流导管,以建立具有选择性心脏停搏的部分或全部体外循环。
    • 3. 发明申请
    • PERFUSION FILTER CATHETER
    • 灌注过滤器导管
    • WO9916382A3
    • 1999-08-05
    • PCT/US9819777
    • 1998-09-23
    • CARDEON CORPMACOVIAK JOHN ALEARY JAMES JSAMSON WILFRED J
    • MACOVIAK JOHN ALEARY JAMES JSAMSON WILFRED J
    • A61B17/12A61B17/22A61F2/00A61F2/01A61F2/02
    • A61F2/013A61B17/12022A61B17/12109A61B17/12136A61B17/12172A61B17/221A61B2017/22067A61F2002/011A61F2002/018A61F2002/3008A61F2002/30093A61F2002/30098A61F2210/0019A61F2210/0033A61F2230/0006A61F2230/0067A61F2230/0069A61F2230/008A61F2250/0003A61F2250/0023A61F2250/0098
    • A perfusion filter catheter is used to capture potential emboli within the aorta during heart surgery and cardiopulmonary bypass. An expandable embolic filter assembly having fine filter mesh for capturing macroemboli and microemboli is mounted on a catheter shaft having a perfusion lumen with perfusion ports located upstream of the filter. The embolic filter assembly can be actively or passively deployed within the ascending aortic. An optional outer tube covers the embolic filter assembly to prevent premature deployment. Radiopaque markers, sonoreflective markers and/or an aortic transillumination system are provided to monitor the position of the catheter and the deployment state of the embolic filter assembly. The embolic filter assembly is configured to maximize the effective filter surface area when deployed. Embolic filter assembly configurations described include an elongated cone, a frustum of a cone, a trumpet-shape, a modified trumpet-shape, and helically, circumferentially and longitudinally convoluted shapes, as well as configurations having standoff members for centering the filter and holding the filter mesh away from the aortic walls when deployed. Oxygenated blood is perfused through the perfusion lumen and any embolic materials that might be dislodged are captured in the deployed embolic filter assembly. Embodiments are also described that combine the perfusion filter catheter with an aortic occlusion device, which may be a toroidal balloon, an expandable balloon or a selectively deployable external catheter flow control valve. The combined device allows percutaneous transluminal administration of cardiopulmonary bypass and cardioplegic arrest with protection from undesirable embolic events.
    • 灌注过滤器导管用于在心脏手术和体外循环期间捕获主动脉内的潜在栓塞。 具有用于捕获大血管栓和微栓子的精细过滤网的可膨胀栓塞过滤器组件安装在具有灌注腔的导管轴上,灌注腔位于过滤器的上游。 栓塞过滤器组件可主动地或被动地部署在升主动脉内。 可选的外管覆盖栓塞过滤器组件以防止过早部署。 提供不透射线标记物,超声反射标记物和/或主动脉透射照射系统以监测导管的位置和栓塞过滤器组件的展开状态。 栓子过滤器组件被构造成当部署时使有效过滤器表面面积最大化。 描述的栓塞过滤器组件配置包括细长锥体,锥体,喇叭形状,修改的喇叭形状,以及螺旋形,圆周和纵向回旋形状,以及具有用于对中过滤器并保持 当展开时从主动脉壁远离过滤网。 含氧血液通过灌注腔灌注,任何可能脱落的栓塞材料都被捕获在部署的栓塞过滤器组件中。 还描述了将灌注过滤器导管与主动脉闭塞装置组合的实施例,所述主动脉闭塞装置可以是环形球囊,可膨胀球囊或可选择性部署的外部导管流量控制阀。 联合装置允许经皮腔内管理体外循环和心脏停搏,防止不良栓塞事件。