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1. 发明申请

WO9916382A3 PERFUSION FILTER CATHETER 审中-公开
标题翻译：灌注过滤器导管
公开(公告)号：WO9916382A3
公开(公告)日：1999-08-05
申请号：PCT/US9819777
申请日：1998-09-23
申请人： CARDEON CORP , MACOVIAK JOHN A , LEARY JAMES J , SAMSON WILFRED J
发明人： MACOVIAK JOHN A , LEARY JAMES J , SAMSON WILFRED J
IPC分类号： A61B17/12 , A61B17/22 , A61F2/00 , A61F2/01 , A61F2/02
CPC分类号： A61F2/013 , A61B17/12022 , A61B17/12109 , A61B17/12136 , A61B17/12172 , A61B17/221 , A61B2017/22067 , A61F2002/011 , A61F2002/018 , A61F2002/3008 , A61F2002/30093 , A61F2002/30098 , A61F2210/0019 , A61F2210/0033 , A61F2230/0006 , A61F2230/0067 , A61F2230/0069 , A61F2230/008 , A61F2250/0003 , A61F2250/0023 , A61F2250/0098
摘要： A perfusion filter catheter is used to capture potential emboli within the aorta during heart surgery and cardiopulmonary bypass. An expandable embolic filter assembly having fine filter mesh for capturing macroemboli and microemboli is mounted on a catheter shaft having a perfusion lumen with perfusion ports located upstream of the filter. The embolic filter assembly can be actively or passively deployed within the ascending aortic. An optional outer tube covers the embolic filter assembly to prevent premature deployment. Radiopaque markers, sonoreflective markers and/or an aortic transillumination system are provided to monitor the position of the catheter and the deployment state of the embolic filter assembly. The embolic filter assembly is configured to maximize the effective filter surface area when deployed. Embolic filter assembly configurations described include an elongated cone, a frustum of a cone, a trumpet-shape, a modified trumpet-shape, and helically, circumferentially and longitudinally convoluted shapes, as well as configurations having standoff members for centering the filter and holding the filter mesh away from the aortic walls when deployed. Oxygenated blood is perfused through the perfusion lumen and any embolic materials that might be dislodged are captured in the deployed embolic filter assembly. Embodiments are also described that combine the perfusion filter catheter with an aortic occlusion device, which may be a toroidal balloon, an expandable balloon or a selectively deployable external catheter flow control valve. The combined device allows percutaneous transluminal administration of cardiopulmonary bypass and cardioplegic arrest with protection from undesirable embolic events.
摘要翻译：灌注过滤器导管用于在心脏手术和体外循环期间捕获主动脉内的潜在栓塞。具有用于捕获大血管栓和微栓子的精细过滤网的可膨胀栓塞过滤器组件安装在具有灌注腔的导管轴上，灌注腔位于过滤器的上游。栓塞过滤器组件可主动地或被动地部署在升主动脉内。可选的外管覆盖栓塞过滤器组件以防止过早部署。提供不透射线标记物，超声反射标记物和/或主动脉透射照射系统以监测导管的位置和栓塞过滤器组件的展开状态。栓子过滤器组件被构造成当部署时使有效过滤器表面面积最大化。描述的栓塞过滤器组件配置包括细长锥体，锥体，喇叭形状，修改的喇叭形状，以及螺旋形，圆周和纵向回旋形状，以及具有用于对中过滤器并保持当展开时从主动脉壁远离过滤网。含氧血液通过灌注腔灌注，任何可能脱落的栓塞材料都被捕获在部署的栓塞过滤器组件中。还描述了将灌注过滤器导管与主动脉闭塞装置组合的实施例，所述主动脉闭塞装置可以是环形球囊，可膨胀球囊或可选择性部署的外部导管流量控制阀。联合装置允许经皮腔内管理体外循环和心脏停搏，防止不良栓塞事件。

2. 发明公开

EP2442735A4 IMPROVED APPARATUS AND METHODS FOR HYBRID ENDOSCOPIC AND LAPAROSCOPIC SURGERY 有权转让
标题翻译： VERBESSERTE VORRICHTUNG UND VERFAHRENFÜRGEMISCHTE ENDOSKOPISCHE UND LAPAROSKOPISCHE CHIRURGIE
公开(公告)号：EP2442735A4
公开(公告)日：2017-01-18
申请号：EP10746557
申请日：2010-02-26
申请人： BELSON AMIR , LABY KEITH PHILLIP , LEARY JAMES J
发明人： BELSON AMIR , LABY KEITH PHILLIP , LEARY JAMES J
IPC分类号： A61B17/00 , A61B1/00 , A61B1/04 , A61B1/313 , A61B1/32 , A61B17/02 , A61B17/04 , A61B17/29 , A61B17/32 , A61B17/3201 , A61B17/34 , A61B34/30 , A61B34/37 , A61B90/00 , A61B90/30
CPC分类号： A61B17/00 , A61B1/00087 , A61B1/04 , A61B1/3132 , A61B1/32 , A61B17/00234 , A61B17/0218 , A61B17/0469 , A61B17/0483 , A61B17/29 , A61B17/3201 , A61B17/3423 , A61B34/30 , A61B34/37 , A61B90/361 , A61B2017/00278 , A61B2017/00362 , A61B2017/00411 , A61B2017/00464 , A61B2017/00477 , A61B2017/00539 , A61B2017/00544 , A61B2017/00876 , A61B2017/2901 , A61B2017/2902 , A61B2017/2931 , A61B2017/2943 , A61B2090/306 , A61B2090/3614
摘要： Apparatus and methods are described allow the techniques of endoscopic and laparoscopic surgery to be combined into a minimally invasive hybrid surgical technique called NOTES-assisted laparoscopic surgery. Manual and robotic-controlled versions of a modular laparoscopic tool are described having a small diameter shaft that is delivered laparoscopically to a surgical site. Larger diameter working tips are delivered through a NOTES delivery tube inserted to the surgical site through a natural orifice and joined to the shaft of the modular laparoscopic tool. Larger diameter working tips improve the effectiveness of the modular laparoscopic tools and the number and size of laparoscopic ports used can also be reduced.
摘要翻译：描述的装置和方法允许将内窥镜和腹腔镜手术的技术组合成称为NOTES辅助腹腔镜手术的微创混合外科技术。描述了一种手动和机器人控制的模块化腹腔镜工具，其具有腹腔镜输送到外科手术部位的小直径轴。较大直径的工作尖端通过插入到外科手术部位的NOTES输送管通过自然孔输送并连接到模块化腹腔镜工具的轴上。更大的工作尖端提高了模块化腹腔镜工具的有效性，并且也可以减少所用腹腔镜口的数量和尺寸。

3. 发明公开

EP2490750A4 PORTABLE TOPICAL OXYGEN THERAPY SYSTEM 审中-公开
标题翻译：便携式系统对于局部氧治疗
公开(公告)号：EP2490750A4
公开(公告)日：2013-06-05
申请号：EP10825337
申请日：2010-10-25
申请人： BELSON AMIR , LEARY JAMES J
发明人： BELSON AMIR , LEARY JAMES J
IPC分类号： A61M35/00 , A61H33/14
CPC分类号： A61G10/04 , A61F13/00 , A61F2013/0017 , A61G7/05784 , A61H23/02 , A61H23/0236 , A61H23/0245 , A61H33/14 , A61H2033/143 , A61H2201/0207 , A61H2201/0214 , A61H2201/5058 , A61M35/00
摘要： The present invention provides a topical oxygen therapy system for treating chronic non-healing wounds. The system is configured to be extremely portable, allowing patients to be completely ambulatory during treatment. The topical oxygen therapy system includes an oxygen source and a wound dressing capsule. The oxygen source includes a miniature compressed oxygen cylinder and a miniature pressure regulator that delivers oxygen through an outlet tube to the interior of the wound dressing capsule. The oxygen source may be attached directly to or integrated into the wound dressing capsule. Alternatively, the oxygen source and wound dressing capsule may be separate modules connected by a flexible tube.

4. 发明申请

WO2010098871A3 IMPROVED APPARATUS AND METHODS FOR HYBRID ENDOSCOPIC AND LAPAROSCOPIC SURGERY 审中-公开
标题翻译：混合内镜和手术手术的改进装置及方法
公开(公告)号：WO2010098871A3
公开(公告)日：2012-04-26
申请号：PCT/US2010000584
申请日：2010-02-26
申请人： BELSON AMIR , LABY KEITH PHILLIP , LEARY JAMES J
发明人： BELSON AMIR , LABY KEITH PHILLIP , LEARY JAMES J
IPC分类号： A61B1/018
CPC分类号： A61B17/00 , A61B1/00087 , A61B1/04 , A61B1/3132 , A61B1/32 , A61B17/00234 , A61B17/0218 , A61B17/0469 , A61B17/0483 , A61B17/29 , A61B17/3201 , A61B17/3423 , A61B34/30 , A61B34/37 , A61B90/361 , A61B2017/00278 , A61B2017/00362 , A61B2017/00411 , A61B2017/00464 , A61B2017/00477 , A61B2017/00539 , A61B2017/00544 , A61B2017/00876 , A61B2017/2901 , A61B2017/2902 , A61B2017/2931 , A61B2017/2943 , A61B2090/306 , A61B2090/3614
摘要： Apparatus and methods are described allow the techniques of endoscopic and laparoscopic surgery to be combined into a minimally invasive hybrid surgical technique called NOTES-assisted laparoscopic surgery. Manual and robotic-controlled versions of a modular laparoscopic tool are described having a small diameter shaft that is delivered laparoscopically to a surgical site. Larger diameter working tips are delivered through a NOTES delivery tube inserted to the surgical site through a natural orifice and joined to the shaft of the modular laparoscopic tool. Larger diameter working tips improve the effectiveness of the modular laparoscopic tools and the number and size of laparoscopic ports used can also be reduced.
摘要翻译：描述的装置和方法允许将内窥镜和腹腔镜手术的技术组合成称为NOTES辅助腹腔镜手术的微创混合手术技术。描述了一种手动和机器人控制的模块化腹腔镜工具，其具有腹腔镜输送到外科手术部位的小直径轴。较大直径的工作尖端通过插入到外科手术部位的NOTES输送管通过自然孔口输送并连接到模块化腹腔镜工具的轴上。更大直径的工作提示提高了模块化腹腔镜工具的有效性，也可以减少所用腹腔镜口的数量和尺寸。

5. 发明申请

WO0135839A2 ENDARTERECTOMY APPARATUS AND METHOD 审中-公开
标题翻译： ENDARTERECTOMOMY设备和方法
公开(公告)号：WO0135839A2
公开(公告)日：2001-05-25
申请号：PCT/US0031615
申请日：2000-11-16
申请人： ACUMEN VASCULAR INC , BAKER STEVE G , DEATON DAVID H , LEARY JAMES J
发明人： BAKER STEVE G , DEATON DAVID H , LEARY JAMES J
IPC分类号： A61B17/22
CPC分类号： A61B17/3207 , A61B17/32037 , A61B17/320708 , A61B17/320725 , A61B2017/320012 , A61B2017/320733 , A61B2017/320741
摘要： Improved apparatus and methods are described for performing endarterectomy remotely via intraluminal techniques. A flexible blade dissector has a curved, diamond-shaped flexible dissecting blade mounted on a catheter shaft. The distal edge of the flexible dissecting blade is configured to form a dissecting edge for separating an atheromatous plaque from the medial layer of an artery wall. The flexible blade dissector may incorporate a steering mechanism to direct the flexible dissecting blade along a preferred path within the arterial wall. The endarterectomy method is performed by making an incision into an artery wall and initiating a plane of separation between an atherosclerotic plaque and the medial layer of the artery wall, inserting the flexible blade dissector into the plane of separation and advancing the flexible dissecting blade to longitudinally extend the plane of separation. Optionally, a second flexible blade dissector with a wider dissecting blade may be inserted coaxially over the catheter shaft of the first flexible blade dissector and advanced to laterally expand the plane of separation. Once the plaque has been freed from the entire inner circumference of the arterial lumen, the plane of separation is terminated on the distal and proximal ends, and the plaque is removed from the arterial lumen.
摘要翻译：描述了用于通过腔内技术远程执行内膜切除术的改进的装置和方法。柔性刀片剥离器具有安装在导管轴上的弯曲的钻石形柔性解剖刀片。柔性解剖刀片的远侧边缘构造成形成用于从动脉壁的内侧层分离动脉粥样硬化斑块的解剖边缘。柔性刀片解剖器可以包括转向机构以沿着动脉壁内的优选路径引导柔性解剖刀片。通过将动脉壁切开并在动脉粥样硬化斑块和动脉壁的内侧之间开始分离平面，将柔性刮板分离器插入分离平面并将柔性解剖刀推向纵向，从而进行内膜切除术延长分离平面。可选地，具有较宽解剖刀片的第二柔性刀片剥离器可以同轴地插入到第一柔性刀片解剖器的导管轴上并且前进以横向扩展分离平面。一旦斑块已经从动脉腔的整个内圆周中释放出来，则在远端和近端终止分离平面，并且从动脉管腔移除斑块。

6. 发明申请

WO2011049633A2 PORTABLE TOPICAL OXYGEN THERAPY SYSTEM 审中-公开
标题翻译：便携式局部氧治疗系统
公开(公告)号：WO2011049633A2
公开(公告)日：2011-04-28
申请号：PCT/US2010002832
申请日：2010-10-25
申请人： BELSON AMIR , LEARY JAMES J
发明人： BELSON AMIR , LEARY JAMES J
IPC分类号： A61M5/155
CPC分类号： A61G10/04 , A61F13/00 , A61F2013/0017 , A61G7/05784 , A61H23/02 , A61H23/0236 , A61H23/0245 , A61H33/14 , A61H2033/143 , A61H2201/0207 , A61H2201/0214 , A61H2201/5058 , A61M35/00
摘要： The present invention provides a topical oxygen therapy system for treating chronic non-healing wounds. The system is configured to be extremely portable, allowing patients to be completely ambulatory during treatment. The topical oxygen therapy system includes an oxygen source and a wound dressing capsule. The oxygen source includes a miniature compressed oxygen cylinder and a miniature pressure regulator that delivers oxygen through an outlet tube to the interior of the wound dressing capsule. The oxygen source may be attached directly to or integrated into the wound dressing capsule. Alternatively, the oxygen source and wound dressing capsule may be separate modules connected by a flexible tube.
摘要翻译：本发明提供用于治疗慢性非愈合伤口的局部氧疗系统。该系统被配置为非常便携式，允许患者在治疗期间完全流动。局部氧疗系统包括氧源和伤口敷料胶囊。氧源包括微型压缩氧气瓶和微型压力调节器，其通过出口管将氧气输送到伤口敷料胶囊的内部。氧源可以直接附接到伤口敷料胶囊或整合到伤口敷料胶囊中。或者，氧源和伤口敷料胶囊可以是通过柔性管连接的分离模块。

7. 发明授权

US2121805A Window including inwardly swinging sash 失效
标题翻译：窗口包括向内摆动的窗扇
公开(公告)号：US2121805A
公开(公告)日：1938-06-28
申请号：US8855436
申请日：1936-07-02
申请人： LEARY JAMES J
发明人： LEARY JAMES J
IPC分类号： E06B3/50
CPC分类号： E06B3/5063 , E06B3/50

8. 发明申请

WO9958174A3 CIRCULATORY SUPPORT SYSTEM AND METHOD OF USE FOR ISOLATED SEGMENTAL PERFUSION 审中-公开
标题翻译：循环支持系统和分离分离灌注的使用方法
公开(公告)号：WO9958174A3
公开(公告)日：2000-01-27
申请号：PCT/US9909979
申请日：1999-05-07
申请人： CARDEON CORP
发明人： MACOVIAK JOHN A , SAMSON WILFRED J , BAKER STEVE G , LEARY JAMES J
IPC分类号： A61F2/958 , A61M1/36 , A61M25/00 , A61M25/10
CPC分类号： A61M25/1011 , A61M1/3653 , A61M1/3659 , A61M25/0032 , A61M2025/0034 , A61M2025/0036
摘要： A circulatory support system and method for circulatory support are described for performing cardiopulmonary bypass using differential perfusion and/or isolated segmental perfusion of the circulatory system. The circulatory support system includes one or more venous cannulae for draining blood from the venous side of the patient's circulatory system, one or more arterial cannulae for perfusing the arterial side of the patient's circulatory system, and one or more blood circulation pumps connected between the venous cannulae and the arterial cannulae. The arterial cannulae and the venous cannulae of the circulatory support system may take one of several possible configurations. The circulatory support system is configured to segment a patient's circulatory system into one or more isolated circulatory loops. The circulatory loops may be isolated from one another and/or from the remainder of the patient's circulatory system on the venous side, as well as on the arterial side, for isolated closed loop circulatory support of separate organ systems. The circulatory support system is suitable for use in minimally-invasive cardiac surgery, using thoracoscopic, port-access or minithoracotomy techniques, or for standard open-chest cardiac surgery.
摘要翻译：描述了用于循环支持的循环支持系统和方法，用于使用差异灌注和/或循环系统的分离的分段灌注进行心肺分流术。循环支持系统包括用于从患者循环系统的静脉侧排出血液的一个或多个静脉插管，用于灌注患者循环系统的动脉侧的一个或多个动脉插管和连接在患者循环系统的动脉侧的一个或多个血液循环泵插管和动脉插管。循环支持系统的动脉插管和静脉插管可以采取几种可能的构型之一。循环支持系统被配置为将患者的循环系统分成一个或多个隔离的循环循环。循环循环可以彼此隔离和/或从静脉侧以及动脉侧的患者循环系统的其余部分分离，用于分离的器官系统的闭环循环支持。循环支持系统适用于微创心脏手术，使用胸腔镜，入口口或小切开术技术，或适用于标准开胸心脏手术。

9. 发明专利

AU762196B2 Circulatory support system and method of use for isolated segmental perfusion 未知
公开(公告)号：AU762196B2
公开(公告)日：2003-06-19
申请号：AU3973899
申请日：1999-05-07
申请人： CARDEON CORP
发明人： MACOVIAK JOHN A , SAMSON WILFRED J , BAKER STEVE G , LEARY JAMES J
IPC分类号： A61F2/958 , A61M1/36 , A61M25/00 , A61M25/10

10. 发明专利

CA2314228A1 PERFUSION SHUNT APPARATUS AND METHOD 未知
公开(公告)号：CA2314228A1
公开(公告)日：1999-06-24
申请号：CA2314228
申请日：1998-12-14
申请人： CARDEON CORP
发明人： MACOVIAK JOHN A , SAMSON WILFRED J , LEARY JAMES J
IPC分类号： A61F2/958 , A61M1/36 , A61M29/02 , A61M25/10
摘要： A perfusion shunt apparatus and methods are described for isolating and selectively perfusing a segment of a patient's cardiovascular system and for directing circulatory flow around the isolated segment. An aortic perfusion shunt apparatus is configured for deployment within a patient's aortic arch and methods are described for isolating the aortic arch vessels from the aortic lumen, for selectively perfusing the arch vessels with a fluid and for directing blood flow within the aortic lumen through a shunt past the isolated arch vessels. The perfusion shunt apparatus may be mounted of a catheter or cannula for percutaneous introduction or for direct insertion into a circulatory vessel, such as the aorta. The perfusion shunt apparatus has application for protecting a patient from embolic stroke or hypoperfusion during cardiopulmonary bypass or cardiac surgery and also for selectively perfusing the cerebrovascular circulation with oxygenated blood or with neuroprotective fluids in the presence of risk factors, such as head trauma or cardiac insufficiency. The perfusion shunt apparatus will also find application for selective perfusion of other organ systems within the body.

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