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1. 发明授权

US06649896B2 Method and a device for measuring the spatially averaged intensity of a light beam and a method and a device for regulating a light source 有权
公开(公告)号：US06649896B2
公开(公告)日：2003-11-18
申请号：US10168790
申请日：2002-06-21
申请人： Lukas Birrer , Thomas Caratsch , Olivier Elsenhans , Emad Sarofim , Urban Schnell
发明人： Lukas Birrer , Thomas Caratsch , Olivier Elsenhans , Emad Sarofim , Urban Schnell
IPC分类号： H01L3100
CPC分类号： G01J1/4228 , G01J1/04 , G01J1/0429 , G01J1/1626 , G01J1/32 , G01J1/4257
摘要： A photoelectric module (1) comprises an electrically non-conducting support (2) and a photoelectric element including an array of spatially distributed photoelectric members applied to a surface of the support (2). High simplicity and efficiency is obtained by the double function of module (1) for light transmission or reflection, and spatially averaged light measurement. In a preferred application of module (1) a light source (8, LED) is energized by a driving circuit (9) controlled by an electronic circuit (11). The input of this circuit (11) is connected to the photoelectric module (1), the power delivered to the light source (8) and the intensity of the light beam emitted by the light source being regulated preferably to a constant value by the feedback loop consisting of module (1), electronic circuit (11) and driving circuit (9).

2. 发明授权

US07256035B1 System for thermocycling of fluids in cartridges 失效
标题翻译：墨盒中流体热循环系统
公开(公告)号：US07256035B1
公开(公告)日：2007-08-14
申请号：US10070343
申请日：2000-09-02
申请人： Urban Schnell , Olivier Elsenhans , Thomas Caratsch , Lukas Birrer , Emad Sarofim
发明人： Urban Schnell , Olivier Elsenhans , Thomas Caratsch , Lukas Birrer , Emad Sarofim
IPC分类号： C12M1/34
CPC分类号： B01L7/52 , G01N2035/00366
摘要： System for thermocycling of fluids in cartridges comprising a thermocycling unit in thermal contact with a first substantially planar and heat conducting wall of a cartridge, a light source for transmitting light into the interior of said cartridge through a second light transparent wall of said cartridge which is arranged substantially perpendicular to said first wall, a light detector for detecting light emerging from the interior of the cartridge through said second wall and a fluid providing unit coupled to an inlet of the cartridge for providing the cartridge with fluid and an outlet of the cartridge to drain gas when the cartridge is filled with fluid. The invention further concerns a cartridge for conducting the thermal cycling of fluids.
摘要翻译：包括与筒的第一基本上平面和导热壁热接触的热循环单元的热循环系统，用于通过所述盒的第二透光壁将光透射到所述盒的内部的光源，基本上垂直于所述第一壁布置的光检测器，用于检测通过所述第二壁从所述盒的内部出射的光的光检测器;以及耦合到所述盒的入口的流体供应单元，用于向所述盒提供所述盒的流体和出口，当墨盒充满流体时，排出气体。本发明还涉及用于进行流体热循环的筒。

3. 发明授权

US5795547A Thermal cycler 失效
标题翻译：热循环仪
公开(公告)号：US5795547A
公开(公告)日：1998-08-18
申请号：US735943
申请日：1996-10-23
申请人： Rolf Moser , Lukas Birrer
发明人： Rolf Moser , Lukas Birrer
IPC分类号： G01N33/53 , B01L7/00 , B01L9/06 , G01N35/00 , G01N35/04 , G01N35/10 , B01L9/00 , B01L11/02
CPC分类号： B01L7/52 , B01L9/06 , G01N35/1079
摘要： An apparatus for automatic performance of temperature cycles in a number of test tubes in which each test tube is closed by a closure and contains a predetermined volume of a liquid reaction mixture. The apparatus includes a holder, a computer-controlled automatic control system, and a device for cyclic alteration of the holder temperature. The holder has an arrangement of chambers for holding test tubes with each chamber being adapted to receive one test tube. The holder is constructed of a material of high thermal conductivity, and has an upper surface, a bottom surface and a cylindrical outer wall. Each chamber has an opening located in the upper surface of the holder. The device for cyclic alteration of the temperature of the holder is actuated by the automatic control system. By reducing the dimensions of the device and the power required to operate it, numerous advantages are realized. Such advantages are achieved through the arcuate arrangement of chambers in the holder, and the test tube closure which is piercable by a pipetting needle.
摘要翻译：一种用于在多个试管中自动执行温度循环的装置，其中每个试管由封闭件封闭并包含预定体积的液体反应混合物。该装置包括一个保持器，一个计算机控制的自动控制系统和一个用于循环改变保持器温度的装置。保持器具有用于保持试管的室的布置，每个室适于容纳一个试管。保持器由具有高导热性的材料构成，并且具有上表面，底表面和圆柱形外壁。每个室具有位于保持器的上表面中的开口。用于循环改变保持器温度的装置由自动控制系统启动。通过减小设备的尺寸和操作所需的功率，实现了许多优点。这样的优点通过保持器中的腔室的弓形布置以及由移液针刺穿的试管闭合件来实现。

4. 发明授权

US5616301A Thermal cycler 失效
标题翻译：热循环仪
公开(公告)号：US5616301A
公开(公告)日：1997-04-01
申请号：US301932
申请日：1994-09-07
申请人： Rolf Moser , Lukas Birrer
发明人： Rolf Moser , Lukas Birrer
IPC分类号： G01N33/53 , B01L7/00 , B01L9/06 , G01N35/00 , G01N35/04 , G01N35/10 , B01L9/00
CPC分类号： B01L7/52 , B01L9/06 , G01N35/1079
摘要： An apparatus for automatic performance of temperature cycles in a number of test tubes in which each test tube is closed by a closure and contains a predetermined volume of a liquid reaction mixture. The apparatus includes a holder, a computer-controlled automatic control system, and a device for cyclic alteration of the holder temperature. The holder has an arrangement of chambers for holding test tubes with each chamber being adapted to receive one test tube. The holder is constructed of a material of high thermal conductivity, and has an upper surface, a bottom surface and a cylindrical outer wall. Each chamber has an opening located in the upper surface of the holder. The device for cyclic alteration of the temperature of the holder is actuated by the automatic control system. By reducing the dimensions of the device and the power required to operate it, numerous advantages are realized. Such advantages are achieved through the arcuate arrangement of chambers in the holder, and the test tube closure which is piercable by a pipetting needle.
摘要翻译：一种用于在多个试管中自动执行温度循环的装置，其中每个试管由封闭件封闭并包含预定体积的液体反应混合物。该装置包括一个保持器，一个计算机控制的自动控制系统和一个用于循环改变保持器温度的装置。保持器具有用于保持试管的室的布置，每个室适于容纳一个试管。保持器由具有高导热性的材料构成，并且具有上表面，底表面和圆柱形外壁。每个室具有位于保持器的上表面中的开口。用于循环改变保持器温度的装置由自动控制系统启动。通过减小设备的尺寸和操作所需的功率，实现了许多优点。这样的优点通过保持器中的腔室的弓形布置以及由移液针刺穿的试管闭合件来实现。

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