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1. 发明授权

US07087065B2 Mesh for pelvic floor repair 有权
标题翻译：骨盆修补网
公开(公告)号：US07087065B2
公开(公告)日：2006-08-08
申请号：US10263933
申请日：2002-10-03
申请人： Ulf Ulmsten , Barbara Schwartz , Rebecca Leibowitz
发明人： Ulf Ulmsten , Barbara Schwartz , Rebecca Leibowitz
IPC分类号： A61B17/04 , A61F13/00
CPC分类号： A61F2/0045 , A61F2/0063 , A61F2250/0017
摘要： A woven mesh is provided for supporting tissue or an organ within a female patient's pelvis, and a method for using the same. The mesh includes a central portion having a width, a length, first and second ends, and first and second side edges, and first and second wing portions extending from the first and second ends of the central portion respectively. The first and second wing portions each have a width, a length, and first and second peripheral edges. The width of the wing portions are each greater than the width of the central portion, and when positioned within the female patient, the central portion is positioned below and supports the tissue or organ. A mesh is also provided having woven fibers with voids therebetween, and having a central portion and first and second ends. The average size of the voids at least in the central portion is at least 25–50 mm2, and when positioned within the patient, the central portion is positioned below and supports the tissue or organ.
摘要翻译：提供用于支撑女性患者骨盆内的组织或器官的编织网及其使用方法。网格包括具有宽度，长度，第一和第二端以及第一和第二侧边缘的中心部分，以及分别从中心部分的第一端和第二端延伸的第一和第二翼部分。第一和第二翼部各自具有宽度，长度以及第一和第二周边边缘。翼部的宽度各自大于中心部分的宽度，并且当定位在雌性患者体内时，中心部分位于下方并支撑组织或器官。还提供了一种网格，其具有在其间具有空隙的编织纤维，并且具有中心部分和第一和第二端部。至少在中心部分的空隙的平均尺寸至少为25-50mm 2，并且当位于患者体内时，中心部分位于下方并支撑组织或器官。

2. 外观设计

USD594218S1 Shoe for women 有权
公开(公告)号：USD594218S1
公开(公告)日：2009-06-16
申请号：US29319226
申请日：2008-06-05
申请人： Barbara Schwartz
设计人： Barbara Schwartz

3. 外观设计

USD586984S1 Pair of women's shoes 有权
公开(公告)号：USD586984S1
公开(公告)日：2009-02-24
申请号：US29319224
申请日：2008-06-05
申请人： Barbara Schwartz
设计人： Barbara Schwartz

4. 发明授权

US06287853B1 Accessory factory function for interferon gamma and its receptor 失效
标题翻译：干扰素γ及其受体的附件因子功能
公开(公告)号：US06287853B1
公开(公告)日：2001-09-11
申请号：US08871572
申请日：1997-06-09
申请人： Sidney Pestka , Serguei Kotenko , Jaemog Soh , Robert J. Donnelly , Thomas M. Mariano , Jeffry R. Cook , Stuart Emanuel , Barbara Schwartz
发明人： Sidney Pestka , Serguei Kotenko , Jaemog Soh , Robert J. Donnelly , Thomas M. Mariano , Jeffry R. Cook , Stuart Emanuel , Barbara Schwartz
IPC分类号： C12N1563
CPC分类号： C07K14/705 , C07K14/7156
摘要： This invention relates (a) to a 540 kb YAC which encodes the necessary species-specific factor(s) and is able to substitute for human Chromosome 21 to reconstitute the Hu-IFN-gamma receptor-mediated induction of class I HLA antigens; (b) to the construction of a plasmid to integrate the selective marker for antibiotic G418 resistance into YACs and to delete some of the human DNA fragments from YACs in order to facilitate the manipulation of human genomic DNA in yeast artificial chromosome (YAC) clones; (c) to two fragmentation vectors, pSE1 and pSE2, which contain a neomycin resistance and URA3 gene, developed for targeting yeast artificial chromosomes (YACs) containing human genomic DNA; (d) to a chromosomal fragmentation procedure employed to produce a deletion set of yeast artificial chromosomes (YACs) from a parental YAC (GART D142H8) known to map to Chromosome 21q and to encode the human interferon-gamma receptor (Hu-IFN-gamma R) accessory factor gene as well as the phosphoribosylglycinamide formyltranisferase (GART) gene; and (e) to the isolation of cDNA clones that encode the necessary species-specific factor and that are able to substitute for human Chromosome 21 to reconstitute the Hu-IFN-gamma receptor-mediated induction of class I HLA antigens.
摘要翻译：本发明涉及（a）编码所需物种特异性因子的540kb YAC，并且能够代替人染色体21重建Hu-IFN-γ受体介导的I类HLA抗原的诱导; （b）构建质粒，将抗生素G418抗性的选择性标记整合到YAC中，并从YAC中删除一些人DNA片段，以便于酵母人造染色体（YAC）克隆中人基因组DNA的操作; （c）包含含有新霉素抗性和URA3基因的两个片段化载体pSE1和pSE2，用于靶向含有人基因组DNA的酵母人造染色体（YAC）; （d）涉及从已知映射到染色体21q并编码人干扰素-γ受体（Hu-IFN-γ）的亲本YAC（GART D142H8）产生一组缺失的酵母人造染色体（YAC）的染色体片段化方法 R）辅助因子基因以及磷酸核糖基甘氨酰甲酰甲酰氨基转移酶（GART）基因; 和（e）分离编码必需物种特异性因子的cDNA克隆，并能够代替人染色体21重建Hu-IFN-γ受体介导的I类HLA抗原的诱导。