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1. 发明申请

WO2005114708A3 CARBON NANOTUBE-SILICON COMPOSITE STRUCTURES AND METHODS FOR MAKING SAME 审中-公开
标题翻译：碳纳米管 - 硅复合结构及其制备方法
公开(公告)号：WO2005114708A3
公开(公告)日：2006-07-20
申请号：PCT/US2005016102
申请日：2005-05-06
申请人： UNIV RICE WILLIAM M , TOUR JAMES M , DYKE CHRISTOPHER A , MAYA FRANCISCO , STEWART MICHAEL , CHEN BO , FLATT AUSTEN K
发明人： TOUR JAMES M , DYKE CHRISTOPHER A , MAYA FRANCISCO , STEWART MICHAEL , CHEN BO , FLATT AUSTEN K
IPC分类号： H01L51/30 , C01B31/02 , H01L21/00
CPC分类号： B82Y30/00 , B82Y10/00 , H01L51/0048 , Y10S977/847 , Y10S977/892
摘要： The present invention is directed toward methods of attaching or grafting carbon nanotubes (CNTs) to silicon , wherein such attaching or grafting occurs via functional groups on either or both of the CNTs and silicon surface. The present invention is also directed to the novel compositions produced by such methods. In some embodiments, the present invention is directed to afford the covalent attachment of individualized (unroped) SWNTs to Si surfaces.
摘要翻译：本发明涉及将碳纳米管（CNT）附着或接枝到硅上的方法，其中通过碳纳米管和硅表面中的任一个或两者上的官能团进行这种附着或接枝。本发明还涉及通过这些方法制备的新型组合物。在一些实施方案中，本发明旨在提供个体化（未经处理的）SWNT与Si表面的共价连接。

2. 发明申请

WO2006079005A2 METAL-FREE SILICON-MOLECULE-NANOTUBE TESTBED AND MEMORY DEVICE 审中-公开
标题翻译：无金属硅分子 - 纳米管测试和存储器件
公开(公告)号：WO2006079005A2
公开(公告)日：2006-07-27
申请号：PCT/US2006002222
申请日：2006-01-23
申请人： UNIV RICE WILLIAM M , TOUR JAMES M , HE JIANLI , CHEN BO , FLATT AUSTEN K , STEPHENSON JASON J , DOYLE CONDELL D
发明人： TOUR JAMES M , HE JIANLI , CHEN BO , FLATT AUSTEN K , STEPHENSON JASON J , DOYLE CONDELL D
IPC分类号： A22C9/00 , H01L21/34
CPC分类号： G11C13/02 , B82Y10/00 , B82Y30/00 , G11C13/0014 , G11C13/025 , H01L27/283 , H01L51/0048 , H01L51/005 , H01L51/0052 , H01L51/0595
摘要： Work from several laboratories has shown that metal nanofilaments cause problems in some molecular electronics testbeds. A new testbed for exploring the electrical properties of single molecules has been developed to eliminate the possibility of metal nanofilament formation and to ensure that molecular effects are measured. This metal-free system uses single-crystal silicon and single-walled carbon nanotubes as electrodes for the molecular monolayer. A direct Si-arylcarbon grafting method is used. Use of this structure with 7t-conjugated organic molecules results in a hysteresis loop with current-voltage measurements that are useful for an electronic memory device. The memory is non-volatile for more than 3 days, non-destructive for more than 1 ,000 reading operations and capable of more than 1 ,000 write- erase cycles before device breakdown. Devices without 7T-conjugated molecules (Si-H surface only) or with long-chain alkyl-bearing molecules produced no hysteresis, indicating that the observed memory effect is molecularly relevant.
摘要翻译：几个实验室的工作表明，金属纳米丝在一些分子电子测试台中引起问题。已经开发了用于探索单分子的电性质的新试验台，以消除金属纳米丝形成的可能性并确保测量分子效应。该无金属系统使用单晶硅和单壁碳纳米管作为分子单层的电极。使用直接的Si-芳基碳接枝方法。使用这种结构与7t共轭有机分子导致电流 - 电压测量的滞后回路，这对电子存储器件是有用的。存储器非易失性超过3天，对于超过1,000次读取操作无损坏，并且在器件击穿之前能够执行超过1,000次写擦除周期。没有7T共轭分子（仅含Si-H表面）或具有长链烷基的分子的器件没有产生滞后现象，表明观察到的记忆效应是分子相关的。

3. 发明公开

EP2895068A4 SYSTEM AND METHOD FOR MEASURING CARDIAC OUTPUT 审中-公开
标题翻译：系统和方法测量心脏体积
公开(公告)号：EP2895068A4
公开(公告)日：2016-10-12
申请号：EP13836784
申请日：2013-08-22
申请人： COVIDIEN LP , CHEN BO , WOOD LOCKETT
发明人： CHEN BO , WOOD LOCKETT
IPC分类号： A61B5/1455 , A61B5/029 , A61B6/00 , A61B8/00
CPC分类号： A61B5/14551 , A61B5/0095 , A61B5/029 , A61B5/0836

4. 发明申请

WO2007079316A3 INDICATORS FOR A SPECTROPHOTOMETRIC SYSTEM 审中-公开
标题翻译：分光光度计系统的指标
公开(公告)号：WO2007079316A3
公开(公告)日：2007-11-29
申请号：PCT/US2006061678
申请日：2006-12-06
申请人： CAS MEDICAL SYSTEMS INC , BENNI PAUL , CHEN BO , KERSEY ANDREW
发明人： BENNI PAUL , CHEN BO , KERSEY ANDREW
IPC分类号： A61B5/00
CPC分类号： A61B5/6814 , A61B5/0073 , A61B5/14553 , A61B5/4076 , A61B5/742
摘要： A near-infrared spectrophotometpc system (e g, a cerebral oximeter) includes a sensor portion and a monitor portion The monitor portion includes a processor that runs an algorithm which utilizes the amount of detected light to determine the value of the oxygen concentration The monitor portion also includes a visual display that displays the determined oxygen concentration values in vanous formats The monitor portion may also include an audible device (e g, a speaker), that provides audible indications of the determined oxygen concentration values Vanous visual indicators may include, for example, color-coded graphs of the determined oxygenation values to alert the system user whether one hemisphere or region of the brain is in danger of adverse and potentially permanent damage Also, data may be pre-processed by selecting the most clinically concerning sensor value (e g, the sensor with the lowest value), and displaying only that sensor value and its identification on the display screen.
摘要翻译：近红外分光光度计系统（例如，脑血氧计）包括传感器部分和监视部分。监视器部分包括运行利用检测光量来确定氧浓度值的算法的处理器。监视器部分还包括以肮脏格式显示确定的氧浓度值的视觉显示。监视器部分还可以包括提供所确定的氧浓度值的可听指示的可听设备（例如，扬声器）。多个可视指示符可以包括例如颜色确定的氧合值的编码图，以警告系统用户脑中的一个半球或区域是否存在不利和潜在的永久性损伤的危险。另外，可以通过选择临床上最为关键的传感器值来预处理数据（例如，传感器具有最低值），并且仅在显示屏上显示该传感器值及其识别 ñ。

5. 发明申请

WO2008137552A2 ANTI-RAGE ANTIBODIES AND METHODS OF USE THEREOF 审中-公开
标题翻译：抗RA抗体及其使用方法
公开(公告)号：WO2008137552A2
公开(公告)日：2008-11-13
申请号：PCT/US2008062231
申请日：2008-05-01
申请人： MEDIMMUNE LLC , MAO SU-YAU , CHEN BO , CHANG CHEW-SHUN , TIAN JANE , CHOWDHURY PARTHA , COYLE ANTHONY , SIMS GARY
发明人： MAO SU-YAU , CHEN BO , CHANG CHEW-SHUN , TIAN JANE , CHOWDHURY PARTHA , COYLE ANTHONY , SIMS GARY
IPC分类号： A61K39/395
CPC分类号： C07K16/28 , C07K2317/56 , C07K2319/30
摘要： Antibodies that bind RAGE and inhibit the binding between RAGE and HMGBl complexed with CpG DNA are disclosed. The antibodies of the present invention and pharmaceutical compositions comprising the same are useful for many purposes, for example, as therapeutics against a wide range conditions characterized by the presence of DNA immune complexes and/or associated with the expression of one or more type-I IFN- inducible gene.
摘要翻译：公开了结合RAGE并抑制RAGE与与CpG DNA复合的HMGB1之间的结合的抗体。本发明的抗体和包含其的药物组合物可用于许多目的，例如作为治疗剂，其针对特征在于存在DNA免疫复合物和/或与一种或多种I型 IFN-诱导型基因。

6. 发明专利

AU2013315993A1 System and method for measuring cardiac output 未知
公开(公告)号：AU2013315993A1
公开(公告)日：2015-01-22
申请号：AU2013315993
申请日：2013-08-22
申请人： CHEN BO , COVIDIEN LP , WOOD LOCKETT
发明人： CHEN BO , WOOD LOCKETT
IPC分类号： A61B5/1455 , A61B5/029 , A61B6/00 , A61B8/00
摘要： Embodiments of the present disclosure relate to a system and method for non-invasively determining a cardiac output of a patient that may include a photoacoustic sensor and a determination of oxygen uptake of the patient. Specifically, a signal from a photoacoustic sensor may be used to determine a mixed venous and an arterial oxygen saturation of the patient. The parameters of mixed venous and arterial oxygen saturation in conjunction with oxygen uptake may be used to calculate cardiac output using the Fick method.

7. 发明专利

AU3717597A Oscillatory roller transmission 未知
公开(公告)号：AU3717597A
公开(公告)日：1998-02-20
申请号：AU3717597
申请日：1997-06-23
申请人： CHEN BO
发明人： CHEN BO , CHEN SHIXIAN , CHEN ZHI
IPC分类号： F16H1/32 , F16H1/28

8. 发明申请

WO2012075419A3 NON-INVASIVE FAT REDUCTION BY HYPERTHERMIC TREATMENT 审中-公开
标题翻译：通过高温处理进行的非侵入性减脂
公开(公告)号：WO2012075419A3
公开(公告)日：2013-01-24
申请号：PCT/US2011063113
申请日：2011-12-02
申请人： CYNOSURE INC , CHEN BO , MIRKOV MIRKO GEORGIEV
发明人： CHEN BO , MIRKOV MIRKO GEORGIEV
IPC分类号： A61B18/20 , A61N5/067
CPC分类号： A61B18/20 , A61B2018/00023 , A61B2018/00464 , A61B2018/00797 , A61N5/062
摘要： The present disclosure relates systems and methods for tissue remodeling, that ameliorate fat deposits by disrupting adipocytes through low-temperature extended treatment time approaches, in conjunction with selective treatment and/or localized cooling of the treatment site to prevent or minimize damage to non-target tissues.
摘要翻译：本公开涉及用于组织重塑的系统和方法，其通过低温延长治疗时间方法破坏脂肪细胞来改善脂肪沉积，结合治疗部位的选择性治疗和/或局部冷却以防止或最小化对非目标的损伤组织。

9. 发明申请

WO2011159938A3 HIGH AFFINITY HUMAN ANTIBODIES TO HUMAN CYTOMEGALOVIRUS (CMV) GB PROTEIN 审中-公开
标题翻译：人类细胞因子（CMV）GB蛋白的高亲和力人体抗体
公开(公告)号：WO2011159938A3
公开(公告)日：2012-04-19
申请号：PCT/US2011040761
申请日：2011-06-16
申请人： TRELLIS BIOSCIENCE INC , KAUVAR LAWRENCE M , ELLSWORTH STOTE , USINGER WILLIAM , MCCUTCHEON KRISTA MAUREEN , JIANG YING-PING , ZHANG FEN , CHEN BO , SPERINDE GIZETTE , PARK MINHA , FOORD ORIT
发明人： KAUVAR LAWRENCE M , ELLSWORTH STOTE , USINGER WILLIAM , MCCUTCHEON KRISTA MAUREEN , JIANG YING-PING , ZHANG FEN , CHEN BO , SPERINDE GIZETTE , PARK MINHA , FOORD ORIT
IPC分类号： A61K39/00 , A61K39/42
CPC分类号： C07K16/088 , A61K39/245 , A61K2039/505 , C07K16/08 , C07K16/468 , C07K2317/14 , C07K2317/21 , C07K2317/30 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92
摘要： Antibodies to human Cytomegalovirus (CMV) gB protein have been isolated from human B cells. The affinities of these antibodies are higher than the best previously reported antibodies. Since high affinity is critical to prevention of virus transfer across the placenta, the invention antibodies are useful as therapeutic and prophylactic agents to prevent or ameliorate effects on the fetus of CMV infection during pregnancy.
摘要翻译：已从人B细胞中分离出人巨细胞病毒（CMV）gB蛋白的抗体。这些抗体的亲和力高于先前报道的最佳抗体。由于高亲和力对于预防跨越胎盘的病毒转移至关重要，本发明的抗体可用作预防或改善对怀孕期间CMV感染胎儿的影响的治疗和预防剂。

10. 发明专利

CA2884793A1 SYSTEM AND METHOD FOR MEASURING CARDIAC OUTPUT 未知
公开(公告)号：CA2884793A1
公开(公告)日：2014-03-20
申请号：CA2884793
申请日：2013-08-22
申请人： COVIDIEN LP , CHEN BO , WOOD LOCKETT
发明人： CHEN BO , WOOD LOCKETT
IPC分类号： A61B5/1455 , A61B5/029 , A61B6/00 , A61B8/00
摘要： Embodiments of the present disclosure relate to a system and method for non-invasively determining a cardiac output of a patient that may include a photoacoustic sensor and a determination of oxygen uptake of the patient. Specifically, a signal from a photoacoustic sensor may be used to determine a mixed venous and an arterial oxygen saturation of the patient. The parameters of mixed venous and arterial oxygen saturation in conjunction with oxygen uptake may be used to calculate cardiac output using the Fick method.

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