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    • 1. 发明申请
    • SELF-REPLICATING MATERIALS
    • 自我复制材料
    • WO2008076414A3
    • 2008-10-09
    • PCT/US2007025749
    • 2007-12-17
    • UNIV NEW YORKSEEMAN NADRIANCHAIKIN PAUL MICHAELPINE DAVIDGRIER DAVID G
    • CHAIKIN PAUL MICHAELPINE DAVIDGRIER DAVID G
    • C12Q1/68
    • C12Q1/682B82Y5/00B82Y20/00C12N15/10C12N15/1031C12N15/1068C12Q2563/155C12Q2565/113
    • The invention provides micron and sub-micron scale particles designed to recognize and selectively interact with each other by exploiting the recognition and specificity enabled by DNA-sequence-encoded coatings. Such materials possess sufficient information coded in their chemical and physical interactions to self assemble and self replicate. The invention further provides methods of using such materials to create self replicating and organizing materials. Replicated copies are permanently linked and then thermally detached, freeing them to act as templates for further growth. This new class of condensed matter systems, provides means to design and control the structure and function of materials and machines from the microscopic to life-size. In another aspect of the invention, depletion type forces and depletion zones can be utilized in the implementation of the self assembly and self replication of materials, including without limitation colloidal particles. The invention further provides novel means of synthesis and materials built by such synthesis, which may be used in a variety of applications, including microelectronics.
    • 本发明提供了设计成通过利用由DNA序列编码的涂层实现的识别和特异性来识别和选择性地彼此相互作用的微米级和亚微米级颗粒。 这些材料在其化学和物理相互作用中具有编码足够的信息以自我组装和自我复制。 本发明还提供了使用这种材料来产生自我复制和组织材料的方法。 复制副本永久链接,然后散热,释放它们作为进一步增长的模板。 这种新型凝结物质系统提供了设计和控制材料和机器从微观到实际尺寸的结构和功能的手段。 在本发明的另一方面,耗尽型力和耗尽区可用于实施材料的自组装和自我复制,包括但不限于胶体颗粒。 本发明进一步提供了新颖的合成手段和通过这种合成建立的材料,其可以用于各种应用,包括微电子学。