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1. 发明申请

WO2010057141A3 ALPHAVIRUS INHIBITORS AND USES THEREOF 审中-公开
标题翻译： ALPHAVIRUS抑制剂及其用途
公开(公告)号：WO2010057141A3
公开(公告)日：2010-09-16
申请号：PCT/US2009064672
申请日：2009-11-17
申请人： UNIV MICHIGAN , MILLER DAVID J , PELTIER DANIEL C , PENG WEIPING
发明人： MILLER DAVID J , PELTIER DANIEL C , PENG WEIPING
IPC分类号： C07D495/04 , A61K31/4535 , A61P31/12 , C07D409/14
CPC分类号： C07D495/04 , A61K31/4535
摘要： The present invention relates to chemical compounds, methods for their discovery, and their therapeutic use. In particular, the present invention provides compounds as inhibitors of alphaviruses.
摘要翻译：本发明涉及化学化合物，其发现方法及其治疗用途。特别地，本发明提供作为甲病毒抑制剂的化合物。

2. 发明申请

WO2012170098A3 ARBOVIRUS INHIBITORS AND USES THEREOF 审中-公开
标题翻译： ARBOVIRUS抑制剂及其用途
公开(公告)号：WO2012170098A3
公开(公告)日：2013-01-31
申请号：PCT/US2012029634
申请日：2012-03-19
申请人： UNIV MICHIGAN , LARSEN SCOTT , SINDAC JANICE , BARRAZA SCOTT , MILLER DAVID J
发明人： LARSEN SCOTT , SINDAC JANICE , BARRAZA SCOTT , MILLER DAVID J
IPC分类号： C07D401/14 , A61K31/4439 , A61P31/12 , C07D401/06
CPC分类号： C07D401/06 , C07D401/14 , C07D471/04 , C07D491/048
摘要： The present invention relates to chemical compounds, methods for their discovery, and their therapeutic use. In particular, the present invention provides compounds as inhibitors of arboviruses.
摘要翻译：本发明涉及化合物，其发现方法及其治疗用途。特别地，本发明提供了作为伞形病毒抑制剂的化合物。

3. 发明公开

EP0118531A4 APPARATUS AND METHOD FOR UNLOADING BULK MATERIALS. 失效
标题翻译： VORRICHTUNG UND VERFAHREN ZUM ENTLADEN VON MASSENGUT。
公开(公告)号：EP0118531A4
公开(公告)日：1985-03-06
申请号：EP83902941
申请日：1983-09-01
申请人： MILLER DAVID J , MILLER ALLEN R , MILLER CHARLES P
发明人： MILLER DAVID J
IPC分类号： B65G65/02 , B65G53/48 , B65G65/16 , B65G65/22 , B65G67/60 , B65G67/62 , B65G63/04
CPC分类号： B65G67/606 , B65G53/48 , B65G65/22
摘要： An unloader (8) for bulk materials (3) to transfer material such as cement from a barge (2) or other bulk container. It includes a moveable and rotatable support (12) such as a crane or cantilevered arm that is adjacent the bulk container. A first conveyor (14) or auger is connected to the support for pivotal movement and extends generally horizontally. A second conveyor (16) or auger is connected to the distal end of the first conveyor for pivotal movement and is generally vertically oriented. A feeder (18) is connected to the distal end of the second conveyor for universal and rotational movement. The feeder includes an uplift portion (72) communicating with the second conveyor, the uplift portion advancing the bulk material at a rate slower than the second conveyor, and a collector portion (74) communicating with the uplift portion. The collector portion includes converging augers (80, 82) to advance the bulk material towards the uplift portion and to assist in transferring it into the uplift portion. The apparatus may further include a selectively operable energy responsive aeration system (150, 152, 154) to inject air into the bulk material while it is being handled by the unloader, a scraper (110, 112) attached to the feeder to assist in removing the last of the bulk material from its container, and a take-away mechanism (130) to transport the bulk material away from the unloader.
摘要翻译：用于散装材料（3）的卸载器（8），用于从驳船（2）或其他散装容器转移诸如水泥的材料。它包括可移动和可旋转的支撑件（12），例如与散装容器相邻的起重机或悬臂。第一输送机（14）或螺旋输送机连接到支撑件用于枢转运动并且大致水平延伸。第二输送机（16）或螺旋钻与第一输送机的远端连接以进行枢转运动并且大致垂直定向。供给器（18）连接到第二传送器的远端以用于通用和旋转运动。供料器包括与第二输送器连通的隆起部分（72），隆起部分以比第二输送器慢的速率使松散材料前进，以及与隆起部分连通的收集器部分（74）。收集器部分包括会聚螺旋推进器（80,82），以将松散材料推向隆起部分并帮助将其转移到隆起部分中。该设备可以进一步包括可选择性操作的能量响应曝气系统（150,152,154），以在空气材料被卸载器处理时将空气注入散装材料中，刮板（110,112）连接到馈送器以帮助移除来自其容器的最后一批散装物料和用于将散装物料从卸载装置运走的卸料机构（130）。

4. 发明专利

DE3390175T1 未知
公开(公告)号：DE3390175T1
公开(公告)日：1985-04-18
申请号：DE3390175
申请日：1983-09-01
申请人： MILLER DAVID J , MILLER ALLEN R , MILLER CHARLES P
发明人： MILLER DAVID J , MILLER ALLEN R , MILLER CHARLES P
IPC分类号： B65G65/02 , B65G53/48 , B65G65/16 , B65G65/22 , B65G67/60 , B65G67/62 , B65G65/38 , B65G69/08 , B65G69/20
摘要： An unloader (8) for bulk materials (3) to transfer material such as cement from a barge (2) or other bulk container. It includes a moveable and rotatable support (12) such as a crane or cantilevered arm that is adjacent the bulk container. A first conveyor (14) or auger is connected to the support for pivotal movement and extends generally horizontally. A second conveyor (16) or auger is connected to the distal end of the first conveyor for pivotal movement and is generally vertically oriented. A feeder (18) is connected to the distal end of the second conveyor for universal and rotational movement. The feeder includes an uplift portion (72) communicating with the second conveyor, the uplift portion advancing the bulk material at a rate slower than the second conveyor, and a collector portion (74) communicating with the uplift portion. The collector portion includes converging augers (80, 82) to advance the bulk material towards the uplift portion and to assist in transferring it into the uplift portion. The apparatus may further include a selectively operable energy responsive aeration system (150, 152, 154) to inject air into the bulk material while it is being handled by the unloader, a scraper (110, 112) attached to the feeder to assist in removing the last of the bulk material from its container, and a take-away mechanism (130) to transport the bulk material away from the unloader.

5. 发明专利

CA876469A CONCRETE CURB LAYING MACHINE 未知
公开(公告)号：CA876469A
公开(公告)日：1971-07-27
申请号：CA876469D
申请人： MILLER DAVID J , MILLER CHARLES P , MILLER ALLEN R
发明人： MILLER CHARLES P , MILLER DAVID J , MILLER ALLEN R

6. 发明专利

CA12873A IMPROVEMENTS ON NUT LOCKS 未知
公开(公告)号：CA12873A
公开(公告)日：1881-05-30
申请号：CA12873D
申请人： JOINES HUGH S , MILLER DAVID J
发明人： JOINES HUGH S , MILLER DAVID J

7. 发明专利

CA5601A IMPROVEMENTS ON CALENDARS 未知
公开(公告)号：CA5601A
公开(公告)日：1876-01-20
申请号：CA5601D
申请人： MILLER DAVID J
发明人： MILLER DAVID J

8. 发明专利

DE3390175C2 未知
公开(公告)号：DE3390175C2
公开(公告)日：1991-04-18
申请号：DE3390175
申请日：1983-09-01
申请人： MILLER DAVID J , MILLER ALLEN R , MILLER CHARLES P
发明人： MILLER DAVID J , MILLER ALLEN R , MILLER CHARLES P
IPC分类号： B65G65/02 , B65G53/48 , B65G65/16 , B65G65/22 , B65G67/60 , B65G67/62
摘要： An unloader (8) for bulk materials (3) to transfer material such as cement from a barge (2) or other bulk container. It includes a moveable and rotatable support (12) such as a crane or cantilevered arm that is adjacent the bulk container. A first conveyor (14) or auger is connected to the support for pivotal movement and extends generally horizontally. A second conveyor (16) or auger is connected to the distal end of the first conveyor for pivotal movement and is generally vertically oriented. A feeder (18) is connected to the distal end of the second conveyor for universal and rotational movement. The feeder includes an uplift portion (72) communicating with the second conveyor, the uplift portion advancing the bulk material at a rate slower than the second conveyor, and a collector portion (74) communicating with the uplift portion. The collector portion includes converging augers (80, 82) to advance the bulk material towards the uplift portion and to assist in transferring it into the uplift portion. The apparatus may further include a selectively operable energy responsive aeration system (150, 152, 154) to inject air into the bulk material while it is being handled by the unloader, a scraper (110, 112) attached to the feeder to assist in removing the last of the bulk material from its container, and a take-away mechanism (130) to transport the bulk material away from the unloader.

9. 发明申请

WO2011119195A3 MODERN HYDRIDE VAPOR-PHASE EPITAXY SYSTEM & METHODS 审中-公开
标题翻译：现代氢气蒸气相外延系统与方法
公开(公告)号：WO2011119195A3
公开(公告)日：2012-01-12
申请号：PCT/US2010062610
申请日：2010-12-30
申请人： CBL TECHNOLOGIES INC , SOLOMON GLENN S , MILLER DAVID J
发明人： SOLOMON GLENN S , MILLER DAVID J
IPC分类号： H01L21/205
CPC分类号： C30B29/406 , C30B25/08 , C30B25/10
摘要： Hydride vapor-phase deposition (HVPE) systems are disclosed. An HVPE hydride vapor-phase deposition system may include a reactant source chamber and a growth chamber containing a susceptor coupled to the reactant source chamber. The reactant source chamber may be configured to create a reactant gas through a chemical reaction between a solid or liquid precursor and a different precursor gas. The reactant source chamber can be configured to operate at a temperature T(M) significantly above room temperature. The reactant gas can be chemically unstable at or near room temperature. The susceptor is configured to receive a substrate and maintain the substrate at a substrate temperature T(S). The growth chamber includes walls can be configured to operate at a temperature T(C) such that T(M), T(S) are greater than T(C).
摘要翻译：公开了氢化物气相沉积（HVPE）系统。 HVPE氢化物气相沉积系统可以包括反应物源室和包含耦合到反应物源室的基座的生长室。反应物源室可经配置以通过固体或液体前体与不同前体气体之间的化学反应产生反应气体。反应物源室可以被配置为在明显高于室温的温度T（M）下操作。反应物气体在室温或室温下可能化学不稳定。基座构造成接收基板并将基板保持在基板温度T（S）。生长室包括壁可被配置成在温度T（℃）下操作使得T（M），T（S）大于T（℃）。

10. 发明申请

WO2004077012A3 METHODS AND SYSTEMS FOR CONTROLLING AND/OR INCREASING IONTOPHORETIC FLUX 审中-公开
标题翻译：用于控制和/或增加IOPOPHORETIC FLUX的方法和系统
公开(公告)号：WO2004077012A3
公开(公告)日：2006-09-08
申请号：PCT/US2004004126
申请日：2004-02-13
申请人： ACIONT INC , HIGUCHI WILLIAM I , MILLER DAVID J , LI KEVIN S
发明人： HIGUCHI WILLIAM I , MILLER DAVID J , LI KEVIN S
IPC分类号： A61N1/30 , A61N1/32
CPC分类号： A61N1/0428 , A61N1/0436 , A61N1/30 , A61N1/327
摘要： An iontophoretic method is provided to selectively transport a compound of interest through a localized region of an individual's body tissue that exhibits a low electrical resistance and/or a high permeability. The method involves placing a permselective material, typically having a resistance comparable or higher than the resistance of the localized region, in ion-conducting relation to the localized region. An electrical current is then applied through the permselective material to the localized region, thereby transporting the compound of interest iontophoretically through the localized region. When the permselective material is capable of hindering iontophoretic transport of a competing ion, the transference efficiency of the compound of interest is increased during iontophoresis. As a result, the compound of interest is delivered into or extracted from the localized region at an enhanced rate. As transport efficiencies approach unity, absolute predictivity of transport also becomes possible. Also provided are electrode assemblies and iontophoretic systems capable of carrying out the iontophoretic method.
摘要翻译：提供离子电渗疗法以选择性地将感兴趣的化合物输送通过显示低电阻和/或高渗透性的个体身体组织的局部区域。该方法包括将通常具有与局部区域的电阻相当或更高的电阻的选择性选择材料置于与局部区域的离子传导关系中。然后通过选择选择材料将电流施加到局部区域，从而通过局部区域输送离子电渗透的化合物。当选择选择性材料能够阻碍竞争离子的离子电渗转运时，在离子电渗中增加感兴趣的化合物的转移效率。结果，感兴趣的化合物以增强的速率被递送到局部区域或从局部区域提取。随着运输效率达到统一，运输的绝对预测也成为可能。还提供了能够进行离子电渗法的电极组件和离子电渗系统。

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