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1. 发明申请

WO0051554A3 REGULATING SKIN APPEARANCE AND COMPOSITION WITH A FLUORINATED VITAMIN D3 ANALOG COMPOUND 审中-公开
标题翻译：用荧光维生素D3模拟化合物调节皮肤外观和组成
公开(公告)号：WO0051554A3
公开(公告)日：2001-01-11
申请号：PCT/US0005414
申请日：2000-03-01
申请人： UNIV JOHNS HOPKINS , BISSETT DONALD LYNN , POSNER GARY H , LEE JAE KYOO , WANG QIANG , TREJO AMY VIOLET
发明人： BISSETT DONALD LYNN , POSNER GARY H , LEE JAE KYOO , WANG QIANG , TREJO AMY VIOLET
IPC分类号： A61K8/67 , A61Q19/08 , A61K7/48
CPC分类号： A61Q19/08 , A61K8/67
摘要： The present invention relates to topical skin care compositions and methods of their use. Such compositions comprise a fluorinated vitamin D3 analog which is useful for regulating skin condition, especially for regulating the signs of skin aging.
摘要翻译：本发明涉及局部皮肤护理组合物及其使用方法。这样的组合物包含氟化维生素D3类似物，其可用于调节皮肤状况，特别是用于调节皮肤老化的迹象。

2. 发明申请

WO2006124990A2 REGULATION OF MAMMALIAN KERATINOUS TISSUE USING PERSONAL CARE COMPOSITIONS COMPRISING CETYL PYRIDINIUM CHLORIDE 审中-公开
标题翻译：使用包含氯乙酸氯化钠的个人护理组合物对马马里兰卡那霉素组织的调节
公开(公告)号：WO2006124990A2
公开(公告)日：2006-11-23
申请号：PCT/US2006019067
申请日：2006-05-17
申请人： PROCTER & GAMBLE , BISSETT DONALD LYNN
发明人： BISSETT DONALD LYNN
IPC分类号： A61K8/37 , A61K8/41 , A61Q7/00 , A61Q19/00 , A61Q19/02
CPC分类号： A61K8/40 , A61K8/416 , A61K8/4926 , A61K8/675 , A61Q19/00 , G06Q50/22
摘要： Personal care composition including a first skin and/or hair care active cetyl pyridinium chloride; and at least one additional skin and/or hair care active selected from the group consisting of tetrahydrocurcumin, sugar amine, vitamin B3, retinoids, hydroquinone, peptides, phytosterol, dialkanoyl hydroxyproline, hexamidine, salicylic acid, n-acyl amino acid compounds, sunscreen actives, water soluble vitamins, oil soluble vitamins, hesperedin, mustard seed extract, glycyrrhizic acid, glycyrrhetinic acid, carnosine, Butylated Hydroxytoluene (BHT) and Butylated Hydroxyanisole (BHA), ergothioneine, vanillin or its derivatives, diethylhexyl syrinylidene malonate, melanostatine, sterol esters, idebenone, dehydroacetic acid, Licohalcone A, creatine, creatinine, feverfew extract, yeast extract, beta glucans, alpha glucans, their salts, their derivatives, their precursors, and/or combinations thereof; and a dermatologically acceptable carrier. The invention further relates to methods for regulating the condition of mammalian keratinous tissue wherein the methods each comprise the step of topically applying to the keratinous tissue of a mammal needing such treatment, a safe and effective amount of the personal care composition of the invention.
摘要翻译：个人护理组合物，包括第一皮肤和/或头发护理活性十六烷基吡啶鎓氯化物; 和至少一种另外的皮肤和/或毛发护理活性物质，其选自四氢姜黄素，糖胺，维生素B3，类视黄醇，氢醌，肽，植物甾醇，二烷酰基羟脯氨酸，己脒，水杨酸，n-酰基氨基酸化合物，防晒剂活性物质，水溶性维生素，油溶性维生素，黄曲霉素，芥子籽提取物，甘草酸，甘草次酸，肌肽，丁酰化羟基甲苯（BHT）和丁基化羟基苯甲醚（BHA），麦角硫素，香草醛或其衍生物，二乙基己基亚乙烯基丙二酸酯，黑色素，酯，艾地苯醌，脱氢乙酸，Licohalcone A，肌酸，肌酸酐，发热提取物，酵母提取物，β葡聚糖，α葡聚糖，其盐，其衍生物，其前体和/或其组合; 和皮肤病学上可接受的载体。本发明还涉及用于调节哺乳动物角质组织状况的方法，其中所述方法各自包括局部施用于需要这种治疗的哺乳动物的角质组织的步骤，安全有效量的本发明的个人护理组合物。

3. 发明申请

WO2008063441A3 PERSONAL CARE COMPOSITION 审中-公开
标题翻译：个人护理组合
公开(公告)号：WO2008063441A3
公开(公告)日：2008-08-21
申请号：PCT/US2007023673
申请日：2007-11-09
申请人： PROCTER & GAMBLE , MILLIKIN CHERI LYNN , BISSETT DONALD LYNN
发明人： MILLIKIN CHERI LYNN , BISSETT DONALD LYNN
IPC分类号： A61K8/37 , A61K8/44 , A61Q19/02 , A61Q19/06 , A61Q19/08
CPC分类号： A61K8/37 , A61K8/41 , A61K8/4973 , A61K8/498 , A61K8/60 , A61K8/63 , A61K8/64 , A61K8/66 , A61K8/67 , A61K8/673 , A61K8/676 , A61K8/678 , A61K8/97 , A61K8/99 , A61K2800/522 , A61Q17/04 , A61Q19/00 , A61Q19/02 , A61Q19/06 , A61Q19/08
摘要： Personal care composition comprising at least one skin care active selected from the group consisting of acetyl glutamic acid, acetyl glutamine, acetyl methionine, acetyl tributyl citrate, acetyl triethyl citrate, acetyl tyrosine, adipic acid, alanine, arginine, arginine glutamate, benzophenone-3, camphor, gluconolactone, glucose, glycine, histidine hydrochloride, hydroxyproline, maltitol, phenylalanine, succinic acid, buffered lactic acid, tris(tetramethylhydroxypiperidinol) citrate, a boswellic acid compound, and salts, isomers, derivatives, and mixtures of any of the foregoing; and a dermatologically acceptable carrier.
摘要翻译：个人护理组合物，其包含至少一种选自乙酰谷氨酸，乙酰谷氨酰胺，乙酰基甲硫氨酸，乙酰柠檬酸三丁酯，乙酰柠檬酸三乙酯，乙酰酪氨酸，己二酸，丙氨酸，精氨酸，精氨酸谷氨酸，二苯甲酮-3 ，樟脑，葡萄糖酸内酯，葡萄糖，甘氨酸，组氨酸盐酸盐，羟脯氨酸，麦芽糖醇，苯丙氨酸，琥珀酸，缓冲乳酸，三（四甲基羟基哌啶醇）柠檬酸盐，乳香酸化合物及其盐，异构体，衍生物和任何前述物质的混合物 ; 和皮肤病学上可接受的载体。

4. 发明申请

WO2004078158A3 REGULATION OF MAMMALIAN KERATINOUS TISSUE USING HEXAMIDINE COMPOSITIONS 审中-公开
标题翻译：使用HEXAMIDINE组合物调理马马里兰KERATINOUS组织
公开(公告)号：WO2004078158A3
公开(公告)日：2005-01-13
申请号：PCT/US2004006499
申请日：2004-03-04
申请人： PROCTER & GAMBLE , BISSETT DONALD LYNN
发明人： BISSETT DONALD LYNN
IPC分类号： A61K8/34 , A61K8/40 , A61K8/43 , A61K8/60 , A61K8/67 , A61Q19/00 , A61Q19/02 , A61Q19/06 , A61Q19/08 , A61K7/48
CPC分类号： A61K8/40 , A61K8/347 , A61K8/43 , A61K8/606 , A61K8/671 , A61K8/675 , A61Q19/00 , A61Q19/007 , A61Q19/02 , A61Q19/06 , A61Q19/08
摘要： The present invention relates to methods for regulating the condition of mammalian keratinous tissue wherein the methods each comprise the step of topically applying to the keratinous tissue of a mammal needing such treatment, a safe and effective amount of a skin care composition comprising: a) a safe and effective amount of a hexamidine compound selected from the group consisting of hexamidine, its salts, and derivatives; b) a safe and effective amount of one or more skin care active selected from the group consisting of sugar amine, vitamin B3, retinoid, peptide, phytosterol, butylated hydroxytoluene and butylated hydroxyanisole, their derivatives, and combinations thereof; and c) a dermatologically acceptable carrier for the hexamidine and the skin care active. In additional embodiments, the above composition is suitable for preventing, retarding, and/or treating dark under-eye circles, puffy eyes, sagging, sallowness as well as spider vessels and/or red blotchiness of skin, promoting skin desquamation, exfoliation, and/or turnover, regulating and/or reducing pore size appearance, preventing/retarding tanning, regulating oily/shiny appearance, preventing, retarding, and/or treating hyperpigmentation in mammalian skin, preventing, retarding, and/or treating itchiness of mammalian skin, preventing, retarding, and/or treating dryness of skin, preventing, retarding, and/or treating fine lines and wrinkles, preventing, retarding, and/or treating skin atrophy of mammalian skin, softening and/or smoothing lips, hair and nails of a mammal, and preventing, retarding, and/or treating the appearance of cellulite in mammalian skin.
摘要翻译：本发明涉及用于调节哺乳动物角质组织状况的方法，其中各方法包括局部施用于需要这种治疗的哺乳动物的角质组织的步骤，安全有效量的皮肤护理组合物，其包含：a）安全有效量的选自己脒，其盐和衍生物的己脒化合物; b）安全有效量的一种或多种选自糖胺，维生素B3，类视色素，肽，植物甾醇，丁基化羟基甲苯和丁基化羟基苯甲醚，其衍生物及其组合的护肤活性物质; 和c）用于己脒和皮肤护理活性的皮肤病学可接受的载体。在另外的实施方案中，上述组合物适合于预防，延缓和/或治疗黑眼圈，浮肿眼睛，下垂，黄斑以及蜘蛛血管和/或皮肤红斑，促进皮肤脱屑，剥脱和 /或周转，调节和/或减少毛孔外观，防止/阻滞鞣制，调节油性/光泽外观，预防，延缓和/或治疗哺乳动物皮肤色素沉着过度，预防，延缓和/或治疗哺乳动物皮肤的瘙痒，防止，延缓和/或治疗皮肤的干燥，预防，延缓和/或治疗细纹和皱纹，预防，延缓和/或治疗哺乳动物皮肤的萎缩，软化和/或平滑唇，头发和指甲哺乳动物，并且预防，延缓和/或治疗哺乳动物皮肤中脂肪团的外观。

5. 发明申请

WO2008104941A3 PERSONALCARE COMPOSITION COMPRISING BOTANICAL EXTRACT OF FICUS BENGHALENSIS 审中-公开
标题翻译：包含FICUS BENGHALENSIS的植物提取物的个人化组合物
公开(公告)号：WO2008104941A3
公开(公告)日：2008-11-06
申请号：PCT/IB2008050705
申请日：2008-02-27
申请人： PROCTER & GAMBLE , MILLIKIN CHERI LYNN , GOODMAN LAURA JACKSON , BISSETT DONALD LYNN , ROBINSON LARRY RICHARD , OSBORNE ROSEMARIE
发明人： MILLIKIN CHERI LYNN , GOODMAN LAURA JACKSON , BISSETT DONALD LYNN , ROBINSON LARRY RICHARD , OSBORNE ROSEMARIE
IPC分类号： A61K8/97 , A61K36/60 , A61P17/16 , A61P17/18 , A61Q19/02 , A61Q19/08
CPC分类号： A61K36/60 , A61K8/97 , A61K36/82 , A61Q19/02 , A61Q19/08
摘要： Personal care composition comprising at least one extract selected from the group consisting of extracts of Terminalia bellerica, Butea monosperma, Mallotus philippinensis, Anogeissus latifolia, Innula racemosa, Ficus benghalensis, Nerium indicum, Psoralea corylifolia, Acacia catechu, Abies pindrow, Cedrus deodara, Emblica officinalis, Moringa oleifera, Glycyrrhiza glabra, and mixtures thereof; and a dermatologically acceptable carrier. Additionally or alternatively, the composition may comprise 2-hexyldecanol.
摘要翻译：个人护理组合物，其包含至少一种提取物，所述提取物选自由以下组成的组：提取物，所述组提取物包括Terminate bellerica，Butea monosperma，Mallotus philippinensis，Anogeissus latifolia，Innula racemosa，Ficus benghalensis，Nerium indicum，Psoralea corylifolia，Acacia catechu，Abies pindrow，Cedrus deodara，Emblica 甘草，甘草，甘草，及其混合物; 和皮肤病学上可接受的载体。另外或替代地，组合物可以包含2-己基癸醇。

6. 发明申请

WO2006121717A3 SKIN CARE COMPOSITIONS CONTAINING IDEBENONE 审中-公开
标题翻译：皮肤护理组合物含有IDEBENONE
公开(公告)号：WO2006121717A3
公开(公告)日：2006-12-28
申请号：PCT/US2006016889
申请日：2006-05-03
申请人： PROCTER & GAMBLE , BISSETT DONALD LYNN , ROBINSON LARRY RICHARD , MITRA SHEKHAR
发明人： BISSETT DONALD LYNN , ROBINSON LARRY RICHARD , MITRA SHEKHAR
IPC分类号： A61Q19/00 , A61K8/35
CPC分类号： A61K31/12 , A61K8/355 , A61Q7/00 , A61Q19/00 , A61Q19/08
摘要： A stable skin care composition, comprising an effective amount of idebenone, at least one additional skin care active, and a dermatologically acceptable carrier. The composition is substantially colorless.
摘要翻译：一种稳定的皮肤护理组合物，其包含有效量的艾地苯醌，至少一种另外的皮肤护理活性物质和皮肤病学可接受的载体。该组合物基本上是无色的。

7. 发明申请

WO2007041548A3 COMPOSITION FOR REGULATION OF MAMMALIAN KERATINOUS TISSUE 审中-公开
标题翻译：用于调节MAMMALIAN KERATINOUS TISSUE的组合物
公开(公告)号：WO2007041548A3
公开(公告)日：2007-08-02
申请号：PCT/US2006038555
申请日：2006-09-29
申请人： PROCTER & GAMBLE , BISSETT DONALD LYNN , MILLIKIN CHERI LYNN
发明人： BISSETT DONALD LYNN , MILLIKIN CHERI LYNN
IPC分类号： A61K8/36 , A61K8/34 , A61K8/41 , A61K8/46 , A61K8/49 , A61Q19/02
CPC分类号： A61Q19/02 , A61K8/34 , A61K8/345 , A61K8/35 , A61K8/362 , A61K8/368 , A61K8/37 , A61K8/42 , A61K8/46 , A61K8/466 , A61K8/4926 , A61K8/602 , A61K8/675 , A61K8/676 , A61K8/678 , A61K31/10 , A61K31/16 , A61K31/192 , A61K31/20 , A61K31/455 , A61K45/06 , A61K2300/00
摘要： Personal care compositions comprising skin and/or hair care actives. Such compositions are useful for regulating the condition of mammalian keratinous tissue needing such treatments, particularly skin lightening. There is provided a personal care composition comprising a safe and effective amount of a first active selected from the group consisting of octadecenedioic acid, methyl sulfonyl methane, an avenythramide compound and combinations thereof .
摘要翻译：包含皮肤和/或护发活性物质的个人护理组合物。这样的组合物可用于调节需要这种治疗的哺乳动物角质组织的状况，特别是减轻皮肤。提供了一种个人护理组合物，其包含安全有效量的选自十八碳烯酸，甲基磺酰甲烷，avenythramide化合物及其组合的第一活性物质。

8. 发明申请

WO2005011627A3 REGULATION OF MAMMALIAN KERATINOUS TISSUE USING N-ACYL AMINO ACID COMPOSITONS 审中-公开
标题翻译：使用N-乙酰氨基酸组成的马马利亚克制组织的调控
公开(公告)号：WO2005011627A3
公开(公告)日：2005-06-09
申请号：PCT/US2004022702
申请日：2004-07-15
申请人： PROCTER & GAMBLE , BISSETT DONALD LYNN , ROBINSON LARRY RICHARD
发明人： BISSETT DONALD LYNN , ROBINSON LARRY RICHARD
IPC分类号： A61K8/368 , A61K8/40 , A61K8/41 , A61K8/42 , A61K8/44 , A61K8/49 , A61K8/60 , A61K8/63 , A61K8/64 , A61K8/67 , A61Q19/00 , A61Q19/02 , A61Q19/04 , A61Q19/08 , A61K7/48
CPC分类号： A61Q19/08 , A61K8/368 , A61K8/42 , A61K8/4913 , A61K8/60 , A61K8/64 , A61K8/671 , A61K8/675 , A61K8/678 , A61Q19/00 , A61Q19/008 , A61Q19/02 , A61Q19/04
摘要： Skin care compositions containing N-acyl amino acid, particularly N-acyl derivatives of Phenylalanine or Tyrosine, their isomers, or their salts; at least one other skin care active selected from sugar amines, vitamin B3, retinoids, peptides, dialkanoyl hydroxyproline, hexamidine, salicylic acid, and phytosterol; and a dermatologically acceptable carrier for the N-acyl amino acid and the skin care active. The invention further relates to methods for regulating the condition of mammalian keratinous tissue wherein the methods each comprise the step of topically applying to the keratinous tissue of a mammal needing such treatment, a safe and effective amount of the skin care composition of the invention.
摘要翻译：包含N-酰基氨基酸，特别是苯丙氨酸或酪氨酸的N-酰基衍生物，它们的异构体或其盐的护肤组合物; 至少一种选自糖胺，维生素B3，类视色素，肽，二烷酰基羟脯氨酸，己脒，水杨酸和植物甾醇的其它护肤活性物质; 以及用于N-酰基氨基酸和皮肤护理活性物质的皮肤病学可接受的载体。本发明还涉及用于调节哺乳动物角质组织状况的方法，其中所述方法各自包括局部施用于需要这种治疗的哺乳动物的角质组织的步骤，安全有效量的本发明的护肤组合物。

9. 发明专利

AU3390400A Regulating skin appearance and composition with a fluorinated vitamin d3 analog compound 未知
公开(公告)号：AU3390400A
公开(公告)日：2000-09-21
申请号：AU3390400
申请日：2000-03-01
申请人： UNIV JOHNS HOPKINS
发明人： BISSETT DONALD LYNN , POSNER GARY H , LEE JAE KYOO , WANG QIANG , TREJO AMY VIOLET
IPC分类号： A61K8/67 , A61Q19/08 , A61K7/00

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