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    • 2. 发明公开
    • METHODS AND DEVICES FOR SUSTAINED RELEASE OF SUBSTANCES
    • VERFAHREN UND VORRICHTUNG ZUR ANHALTENDEN FREISETZUNG VON WIRKSTOFFEN
    • EP3021665A4
    • 2017-03-22
    • EP14826098
    • 2014-07-16
    • UNIV FLORIDA
    • WILLENBERG BRADLEY JKOEHLER PHILIP GBATICH CHRISTOPHER DGEORGIADES GEORGE
    • A01M13/00A01M1/20A01M29/12A61L9/12
    • A01M1/2055A01M1/2027A01M1/2044A01M29/12A61L9/12A61L9/125A61L9/127A61L2209/131
    • Devices that provide timed-release of target compounds absorbed by, or otherwise integrated into, an external housing. The external housing absorbs and facilitates volatilization of the released compound. A permeable cover can be employed as a regulating mechanism to control the rate volatilization from the external housing. One or more reservoirs containing target compound can be contained within one or more internal chambers of the external housing. The one or more reservoirs can release the target compound for absorption by the external housing and/or to make contact with one or more other reservoirs so as to compromise the other reservoirs and release target compound within. A wick can be employed in certain embodiments to transfer target compound from the internal chamber to the external housing to be volatilized. Continued or sequential release of target compound to recharged the external housing achieves a zero order release rate from the external housing.
    • 提供由外部壳体吸收或以其他方式整合到外部壳体中的定时释放靶标化合物的装置。 外壳吸收并促进释放的化合物的挥发。 可以使用可渗透盖作为调节机构来控制从外壳的速率挥发。 包含目标化合物的一个或多个储存器可以包含在外部壳体的一个或多个内部室中。 一个或多个储存器可以释放目标化合物以供外部壳体吸收和/或与一个或多个其它储存器接触,以便损害其它储存器并释放目标化合物。 在某些实施方案中可以使用芯,以将目标化合物从内部室转移到待挥发的外部壳体。 继续或顺序释放目标化合物以再充电外壳可实现与外壳的零级释放速率。