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1. 发明申请

WO2006060680A2 MDA-7 PROTEIN VARIANTS HAVING ANTIPROLIFERATIVE ACTIVITY 审中-公开
标题翻译：具有抗增殖活性的MDA-7蛋白变体
公开(公告)号：WO2006060680A2
公开(公告)日：2006-06-08
申请号：PCT/US2005043673
申请日：2005-12-02
申请人： UNIV COLUMBIA , FISHER PAUL B , GUPTA PANKAJ
发明人： FISHER PAUL B , GUPTA PANKAJ
IPC分类号： A61K38/17 , C07K14/82
CPC分类号： G01N33/5011 , A61K38/00 , A61K45/06 , A61K48/005 , C07K14/47 , C07K14/52 , C07K14/54 , C07K16/244 , C12N15/86 , C12N2710/10343
摘要： The invention relates to the mda-7 gene, its encoded protein and fragments of the proteins. Several of these fragments of the MDA-7 protein exhibit antiproliferative activity and/or inhibited the activity of intact MDA-7. Accordingly, the invention provides, among other things, for methods and compositions that may be used in the treatment of disorders of cell proliferation, including cancer.
摘要翻译：本发明涉及mda-7基因，其编码的蛋白质和蛋白质的片段。 MDA-7蛋白的这些片段中的几个表现出抗增殖活性和/或抑制完整MDA-7的活性。因此，本发明尤其提供了可用于治疗细胞增殖障碍（包括癌症）的方法和组合物。

2. 发明专利

AU2021106406A4 A formulation of medicaments using Lantana Camara for treatment of Skin related diseases and methods thereof 未知
公开(公告)号：AU2021106406A4
公开(公告)日：2021-12-09
申请号：AU2021106406
申请日：2021-08-22
申请人： AGGARWAL ASHUTOSH DR , DAS UJJALKUMAR DR , GUPTA PANKAJ DR , MOKSHA LAXMI DR , SINGH AJAY PAL DR , VIJAYAKUMAR A R DR
发明人： GUPTA PANKAJ , VIJAYAKUMAR A R , DAS UJJALKUMAR , MOKSHA LAXMI , SINGH AJAY PAL , AGGARWAL ASHUTOSH
IPC分类号： C11D9/38 , A61K8/02 , A61K8/34 , A61K8/92 , A61K8/9789 , A61K9/00 , A61K36/85 , A61K47/10 , A61K47/44 , A61P17/00 , A61P31/10 , A61Q19/00 , A61Q19/10
摘要： The present invention relates to A formulation of medicaments using Lantana Camara for treatment of Skin related diseases and methods thereof. This invention particularly relates to the 5 manufacturing of Mantana Soap from Lantana camara L. for maintaining and caring of health of skin in skin disease prone human. The novel preparation of Mantana soap from plant products of Lantana camara L. will be used to care skin in human particularly those sensitive towards skin diseases. It also helps in protecting the human from many common diseases of skin such as eczema and ring worm.

3. 发明申请

WO2007002466A3 ACCESS CONTROL LIST PROCESSOR 审中-公开
标题翻译：访问控制列表处理器
公开(公告)号：WO2007002466A3
公开(公告)日：2007-10-04
申请号：PCT/US2006024578
申请日：2006-06-22
申请人： NETLOGIC MICROSYSTEMS INC , GUPTA PANKAJ
发明人： GUPTA PANKAJ
IPC分类号： G06F12/00
CPC分类号： G11C15/00
摘要： An integrated circuit device for processing an access control list. The integrated circuit device includes a first content addressable memory (CAM) including a plurality of CAM blocks [ABO - AB63] to generate respective match indices (209), each match index indicating a storage location within the corresponding CAM block of an entry that matches a search key (202). The integrated circuit device further includes a plurality of memory arrays to receive the match indices (209) from the CAM blocks and to output respective lookup values from storage locations indicated by the match indices, each lookup value including information that indicates an action to be taken with respect to a packet used to obtain the search key and information that indicates a priority of the action relative to actions indicated by information in others of the lookup values.
摘要翻译：一种用于处理访问控制列表的集成电路装置。集成电路装置包括：第一内容可寻址存储器（CAM），其包括多个CAM块[ABO-AB63]以产生相应的匹配索引（209），每个匹配索引指示匹配的条目的相应CAM块内的存储位置搜索键（202）。集成电路装置还包括多个存储器阵列，以从CAM块接收匹配索引（209），并从由匹配索引指示的存储位置输出相应的查找值，每个查找值包括指示要采取的动作的信息相对于用于获得搜索关键字的分组和指示相对于其他查找值中的信息所指示的动作的动作的优先级的信息。

4. 发明申请

WO03048390A8 A PROCESS FOR THE PREPARATION OF A NON-TOXIC ANTHRAX VACCINE 审中-公开
标题翻译：制备非毒性ANTHRAX疫苗的方法
公开(公告)号：WO03048390A8
公开(公告)日：2004-02-05
申请号：PCT/IN0200048
申请日：2002-03-20
申请人： BHATNAGAR RAKESH , GUPTA PANKAJ , BATRA SMRITI , CHAUHAN VIBHA , SINGH APARNA , AHUJA NIDHI , KUMAR PRAVEEN
发明人： BHATNAGAR RAKESH , GUPTA PANKAJ , BATRA SMRITI , CHAUHAN VIBHA , SINGH APARNA , AHUJA NIDHI , KUMAR PRAVEEN
IPC分类号： C12N15/09 , A61K38/00 , A61K39/00 , A61K39/07 , A61P31/04 , A61P37/02 , C07K2/00 , C07K14/32 , C07K19/00 , C12N1/21 , C12N15/31 , C12N15/70 , C12P21/02
CPC分类号： C07K14/32 , A61K39/00
摘要： Anthrax toxin, comprising of protective antigen (PA), lethal factor (LF) and edema factor (EF) is a major virulent factor of B.anthracis. Protective antigen, PA is the main component of all the vaccines against anthrax. The protective efficacy of PA is greatly increased if small quantities of LF or EF are incorporated into the vaccines. An ideal vaccine against anthrax should contain PA, LF and EF together, but this combination would be toxic. Therefore, the biologically inactive mutant preparations of PA, LF and EF may be used together for better immunoprotection. The present invention describes the method for generation of recombinant vaccine against anthrax, comprising of non-toxic, mutant anthrax toxin proteins. The procedure involves site-directed mutagenesis of the native genes of the toxin proteins, the expression and purification of the mutant proteins and finally characterization of these proteins.
摘要翻译：由保护性抗原（PA），致死因子（LF）和水肿因子（EF）组成的炭疽毒素是甘蓝的主要毒性因子。保护性抗原，PA是所有针对炭疽疫苗的主要成分。如果将小量的LF或EF并入疫苗中，则PA的保护功效大大增加。针对炭疽的理想疫苗应包含PA，LF和EF，但这种组合是有毒的。因此，PA，LF和EF的生物活性突变体制剂可以一起用于更好的免疫保护。本发明描述了用于产生针对炭疽的重组疫苗的方法，其包含无毒的突变体炭疽毒素蛋白质。该方法涉及毒素蛋白质的天然基因的定点突变，突变蛋白的表达和纯化以及这些蛋白质的最终表征。

5. 发明申请

WO2005102019A3 TREATMENT OF FLUIDS AND/OR SLUDGE WITH ELECTRO PLASMA 审中-公开
标题翻译：用等离子体处理流体和/或污泥
公开(公告)号：WO2005102019A3
公开(公告)日：2007-04-12
申请号：PCT/US2005014382
申请日：2005-04-26
申请人： CAP TECHNOLOGIES LLC , DAIGLE EDWARD O , TENHUNDFELD GREGORY J , GUPTA PANKAJ
发明人： DAIGLE EDWARD O , TENHUNDFELD GREGORY J , GUPTA PANKAJ
IPC分类号： C02F1/46 , B01J19/12 , C02F1/48 , C23C16/00 , G01N33/18
CPC分类号： G01N33/18
摘要： A process for the treatment and/or removal of contaminants from a waste water, waste stream, industrial or municipal sludge, metals, oils, organics and other materials consider to be harmful to the environment are removed from the feed stock; in the case of non-metals, mineralized and in the case of metals, plated to the cathode. The present invention provides an apparatus and methods which overcome some of the problems associated with the treatment of wastewater and sludge and offers a new, novel approach to the treatment of waste, by employing the use of electroplasma processing which utilizes aspects of ultraviolet blue light, thermal energy, cavitation, flocculation, aeration, and electrical energy. The ability to control flow rates, energy density, cavitation density, aeration density and heat generation within the system offers a new level of control over different materials for treatment of waste, contaminants or metals within the same process and apparatus.
摘要翻译：废弃物，废水，工业或城市污泥，金属，油，有机物和被认为对环境有害的其他物质污染物的处理和/或去除方法从原料中除去; 在非金属的情况下，矿化并在金属的情况下镀到阴极。本发明提供了一种克服与污水和污泥处理相关的一些问题的设备和方法，并提供了一种新的新颖的处理废物的方法，通过使用利用紫外线蓝光的方面的电镀处理，热能，空化，絮凝，曝气和电能。控制系统内流量，能量密度，气穴密度，通气密度和发热量的能力，可以在不同的材料上进行新的控制，以处理同一工艺和设备中的废物，污染物或金属。

6. 发明公开

EP1817060A4 MDA-7 PROTEIN VARIANTS HAVING ANTIPROLIFERATIVE ACTIVITY 审中-公开
标题翻译： MDA-7蛋白具有抗增殖活性的变体
公开(公告)号：EP1817060A4
公开(公告)日：2008-05-07
申请号：EP05852788
申请日：2005-12-02
申请人： UNIV COLUMBIA
发明人： GUPTA PANKAJ , FISHER PAUL B
IPC分类号： A61K48/00 , G01N1/10
CPC分类号： G01N33/5011 , A61K38/00 , A61K45/06 , A61K48/005 , C07K14/47 , C07K14/52 , C07K14/54 , C07K16/244 , C12N15/86 , C12N2710/10343
摘要： The invention relates to the mda-7 gene, its encoded protein and fragments of the proteins. Several of these fragments of the MDA-7 protein exhibit antiproliferative activity and/or inhibited the activity of intact MDA-7. Accordingly, the invention provides, among other things, for methods and compositions that may be used in the treatment of disorders of cell proliferation, including cancer.

7. 发明专利

CA2589644A1 MDA-7 PROTEIN VARIANTS HAVING ANTIPROLIFERATIVE ACTIVITY 未知
公开(公告)号：CA2589644A1
公开(公告)日：2006-06-08
申请号：CA2589644
申请日：2005-12-02
申请人： UNIV COLUMBIA
发明人： GUPTA PANKAJ , FISHER PAUL B
IPC分类号： A61K48/00 , G01N1/10
摘要： The present invention provides protein-based biomarkers and biomarker combinations that are useful in qualifying bladder cancer status in a patient. In particular, the biomarkers of this invention are useful to classify a subject sample as bladder cancer or non-bladder cancer. The biomarkers can be detected by SELDI mass spectrometry.

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