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1. 发明授权

US5829589A Pen needle magazine dispenser 失效
标题翻译：笔针杂志机
公开(公告)号：US5829589A
公开(公告)日：1998-11-03
申请号：US928275
申请日：1997-09-12
申请人： Tuan V. Nguyen , Michael A. Dibiasi , Robert E. West , Matthew Murray , Scott Reed , William J. Allen , Jeffrey A. Stein
发明人： Tuan V. Nguyen , Michael A. Dibiasi , Robert E. West , Matthew Murray , Scott Reed , William J. Allen , Jeffrey A. Stein
IPC分类号： A61M5/178 , A61B17/06 , A61M5/00 , A61M5/31 , A61M5/32 , A61M5/34 , B65D83/02 , B65D85/24
CPC分类号： A61M5/002 , A61M5/008 , A61M5/3202 , A61M5/3205 , B65D83/02 , A61M2205/6045 , A61M5/2466 , A61M5/344
摘要： A pen needle magazine dispenser designed to be received and carried in a cap of a medication delivery pen. The dispenser having a cover rotatably mounted on a circular shaped container with a plurality of cavities, wherein each cavity is dimensioned to receive one pen needle. The pen needle being of a type that is forced fit into an adaptor on the pen using threads on the pen needle and corresponding threads in the cavity. The cover includes a slot that is rotated into alignment with one of the cavities in the container to provide the user with access to one unused pen needle and thereby permit the pen needle to be mounted on the pen. After use the used pen needle is returned to the cavity and the cover is rotated until the slot is aligned with another cavity containing the next unused pen needle to be used during the next injection.
摘要翻译：设计用于接收并携带在药物输送笔的帽中的笔针盒分配器。分配器具有可旋转地安装在具有多个空腔的圆形容器上的盖，其中每个空腔的尺寸被设计成接收一个笔针。笔针是强制装配在笔上的适配器上的笔，使用笔针上的螺纹和空腔中的相应螺纹。该盖包括与容器中的其中一个空腔旋转成对准的槽，以使使用者能够访问一个未使用的笔针，从而允许笔针安装在笔上。使用后，使用过的笔针返回到空腔，盖子旋转直到狭缝与下一次注射期间使用的下一个未使用的笔针的另一个空腔对齐。

2. 发明授权

US5672161A Needle assembly having single-handedly activated needle barrier 失效
标题翻译：针组件具有单手激活的针障
公开(公告)号：US5672161A
公开(公告)日：1997-09-30
申请号：US717384
申请日：1996-09-20
申请人： William J. Allen , Jeffrey A. Stein
发明人： William J. Allen , Jeffrey A. Stein
IPC分类号： A61M5/158 , A61M5/32
CPC分类号： A61M5/3202 , A61M5/3269 , A61M2005/3247 , A61M2005/3249 , A61M2205/583
摘要： A needle assembly having a single-handedly activated needle barrier includes a needle cannula having a lumen therethrough. A needle hub having an interior cavity terminating at an open proximal end of the hub is connected to the needle cannula so that the lumen is in fluid communication with the interior cavity. A guide element having a retaining groove therethrough is connected to the needle hub. An elongate barrier arm having a proximal end and a distal end includes a barrier element at its distal end. The barrier element includes a proximal end and a needle passageway therethrough. The barrier arm is positioned within the groove of the guide element and the needle cannula is positioned at least partially within the barrier element. The barrier arm is movable from at least a first retracted position wherein the distal end of the cannula passes through the barrier element so that the distal end of the needle cannula is exposed, to a second extended position wherein the barrier element surrounds the distal end of the needle cannula to help prevent accidental contact with the distal end of the needle cannula. Locking structure to prevent movement of the barrier arm from the second extended position is activated by movement of the barrier arm into the second extended position.
摘要翻译：具有单手激活的针阻挡物的针组件包括具有穿过其中的内腔的针插管。具有终止于轮毂的开放近端的内腔的针毂连接到针插管，使得内腔与内腔流体连通。具有穿过其中的保持槽的引导元件连接到针座。具有近端和远端的细长屏障臂在其远端包括屏障元件。阻挡元件包括通过其的近端和针通路。阻挡臂定位在引导元件的凹槽内，并且针插管至少部分地定位在屏障元件内。阻挡臂可以从至少第一缩回位置移动，其中套管的远端穿过屏障元件，使得针插管的远端露出到第二延伸位置，其中屏障元件围绕着远端针套管有助于防止意外接触针套管的远端。阻挡臂从第二延伸位置移动的锁定结构通过阻挡臂移动到第二延伸位置而被启动。

3. 发明授权

US5158552A Safety trocar instrument having a retractable trocar actuated by relief of pressure on the trocar point 失效
标题翻译：具有伸缩套管针的安全套管针器具通过缓解套管针点上的压力而致动
公开(公告)号：US5158552A
公开(公告)日：1992-10-27
申请号：US787183
申请日：1991-11-04
申请人： Julian F. Borgia , William J. Allen , Jeffrey A. Stein
发明人： Julian F. Borgia , William J. Allen , Jeffrey A. Stein
IPC分类号： A61B17/34 , A61B19/00
CPC分类号： A61B17/3496 , A61B2090/08021
摘要： A safety trocar instrument, for piercing the wall of an anatomical cavity to provide communication with the inside of the cavity, includes a tubular cannula and an elongate trocar having a sharp piercing point. The trocar is mounted for axial reciprocal movement within the cannula between a withdrawn rest position, in which the point is received within and shielded by the distal end of the cannula, a fully extended position in which the point is exposed beyond the distal end of the cannula, and an intermediate retracted position in which the point also is exposed beyond the distal end of the cannula. A retraction spring biases the trocar to its withdrawn position. A latch latches the trocar, in opposition to the retraction spring, for reciprocal movement between the fully extended and intermediate positions. A trip member couples the trocar to the latch member when the trocar moves from the fully extended position to the intermediate position, and trips the latch member when the trocar returns toward the fully extended position to unlatch the trocar and permit it to be moved to the withdrawn position by the retraction spring.

4. 发明授权

US5904693A Automatic laparoscopic ligation clip applicator 失效
标题翻译：自动腹腔镜结扎夹
公开(公告)号：US5904693A
公开(公告)日：1999-05-18
申请号：US346285
申请日：1994-11-23
申请人： Paul C. Dicesare , Jeffrey A. Stein , William J. Allen , Joseph N. Logan , John A. Conners
发明人： Paul C. Dicesare , Jeffrey A. Stein , William J. Allen , Joseph N. Logan , John A. Conners
IPC分类号： A61B17/12 , A61B17/128 , A61B17/00
CPC分类号： A61B17/1285 , Y10S227/901
摘要： A laparoscopic ligation clip applicator for automatically applying a plurality of ligation clips includes a handle assembly having an actuator, an elongated shaft connected to the handle assembly, and an actuating mechanism disposed within the shaft. The actuating mechanism includes a clamp for engaging a first piece of the ligation clip and a slidable driver for driving a second piece of the ligation clip relative to the first piece. The actuating mechanism also includes a hold for preventing rearward movement of the ligation clips, and an advancer for sequentially feeding the ligation clips. A slidable cam, operably connected to the handle assembly, actuates the clamp, the driver and the advancer.
摘要翻译：用于自动施加多个连接夹的腹腔镜结扎夹施加器包括具有致动器的手柄组件，连接到手柄组件的细长轴和设置在轴内的致动机构。所述致动机构包括用于接合所述连接夹的第一片的夹具和用于相对于所述第一片驱动所述连接夹的第二片的可滑动驱动器。致动机构还包括用于防止结扎夹的向后移动的保持器，以及用于顺序地给连接夹的馈送器的推进器。可操作地连接到手柄组件的可滑动凸轮致动夹具，驱动器和推进器。

5. 发明授权

US5830221A Coil fastener applier 失效
标题翻译：线圈紧固件施工机
公开(公告)号：US5830221A
公开(公告)日：1998-11-03
申请号：US717492
申请日：1996-09-20
申请人： Jeffrey A. Stein , William J. Allen , Richard L. Markus , Alan B. Bachman , Deborah M. Bryan , Henry E. Holsten , Stephen A. DeFonzo , Robert C. Savage
发明人： Jeffrey A. Stein , William J. Allen , Richard L. Markus , Alan B. Bachman , Deborah M. Bryan , Henry E. Holsten , Stephen A. DeFonzo , Robert C. Savage
IPC分类号： A61B17/064 , A61B17/068 , A61B17/28 , A61F2/00 , A61B17/08
CPC分类号： A61B17/068 , A61B17/064 , A61B2017/0649 , A61B2017/2923 , A61B2017/2946 , A61F2/0063 , Y10S227/901
摘要： There is provided a surgical coil fastener applier for use in applying helical coil fasteners in surgical procedures, such as hernia repair, to affix surgical mesh to tissue. The coil fastener applier includes a housing having a handle extending therefrom and a trigger pivotally mounted on the housing. An elongated tubular portion extends from the housing and includes a drive rod rotatably supported therein and slidably supporting a plurality of coil fasteners thereon. A drive assembly is provided within the housing to rotate the drive rod and coil fasteners. The drive assembly includes an anti-reverse mechanism to allow rotation of the drive rod in only one direction. An actuation assembly is provided within the housing to convert the motion of the trigger into rotary motion for supply to the drive assembly. The drive assembly includes structure to limit the amount of rotary motion supplied to the drive assembly. The drive assembly further includes a ratchet and pawl mechanism to prevent a partial cycling of the coil fastener applier. Also provided are various coil fasteners for use with the coil fastener applier.
摘要翻译：提供了一种用于在诸如疝修补术的外科手术中应用螺旋线圈紧固件的外科用线圈紧固件敷贴器，以将外科手术网固定到组织上。线圈紧固件施加器包括具有从其延伸的手柄的壳体和枢转地安装在壳体上的触发器。细长的管状部分从壳体延伸并且包括可旋转地支撑在其中并且可滑动地支撑多个线圈紧固件的驱动杆。驱动组件设置在壳体内以旋转驱动杆和线圈紧固件。驱动组件包括防反转机构，以允许驱动杆在仅一个方向上旋转。致动组件设置在壳体内以将触发器的运动转换成旋转运动，以供给驱动组件。驱动组件包括限制提供给驱动组件的旋转运动量的结构。驱动组件还包括棘轮和棘爪机构，以防止线圈紧固件施加器的部分循环。还提供了与线圈紧固件施加器一起使用的各种线圈紧固件。

6. 发明授权

US5465896A Linear surgical stapling instrument 失效
公开(公告)号：US5465896A
公开(公告)日：1995-11-14
申请号：US270399
申请日：1994-07-05
申请人： William J. Allen , Jeffrey A. Stein , Paul DiCesare , Paul Mulhauser , Doug Spranger
发明人： William J. Allen , Jeffrey A. Stein , Paul DiCesare , Paul Mulhauser , Doug Spranger
IPC分类号： A61B17/068 , A61B17/072 , A61B19/00
CPC分类号： A61B17/07207 , A61B2017/07214 , A61B2017/07228 , A61B2090/0814
摘要： A linear surgical stapling instrument includes a magazine for holding a plurality of undeformed surgical staples, and an upper jaw carrying the magazine and having opposed distal and proximal ends. An anvil is formed with staple-deforming pockets, and a lower jaw carries the anvil and has opposing distal and proximal ends respectively configured to mate with the distal and proximal ends of the upper jaw thereby to place the magazine and the anvil in confronting relation. A staple driver is carried in the upper jaw for driving staples held therein toward the anvil. Further, the upper and lower jaws are configured such that, when their respective distal and proximal ends are mated, a gap exists between the jaws in an intermediate region between their respective distal and proximal ends. Finally, a pivotably mounted clamp bar joins the upper and lower jaws and when actuated compresses them together in the intermediate region thereby to narrow the gap and to increase the clamping pressure between the magazine and the anvil. The instrument also includes a blocking system that prevents the jaws from being remated, once having been mated and having had staples in the magazine driven toward the anvil. Still further, the instrument includes a coupling device for coupling the jaws and clamp bar together when the staple driver is actuated.

7. 发明授权

US5312354A Safety trocar instrument having a retractable point actuated by a trigger sleeve 失效
标题翻译：具有由触发套筒致动的可伸缩点的安全套管针器具
公开(公告)号：US5312354A
公开(公告)日：1994-05-17
申请号：US787182
申请日：1991-11-04
申请人： William J. Allen , Jeffrey A. Stein
发明人： William J. Allen , Jeffrey A. Stein
IPC分类号： A61B17/34 , A61M5/20
CPC分类号： A61B17/3496
摘要： A safety trocar instrument, for piercing the wall of an anatomical cavity to provide communication with the inside of the cavity, includes a tubular cannula and an elongate trocar having a sharp piercing point. The trocar is mounted for axial reciprocal movement within the cannula between a withdrawn rest position in which the point is received within and shielded by the distal end of the cannula and a projecting position in which said point is exposed beyond the distal end of the cannula. A retraction spring biases the trocar to its withdrawn position. A latch latches the trocar in the projecting position in opposition to the retraction spring, and a trip member can trip the latch to unlatch the trocar and thereby permit the trocar to be moved to its withdrawn rest position by the retraction spring. A mechanical trigger in the form of a trigger sleeve is mounted within the instrument. Its distal end is locatable between the extreme of said trocar point and the distal end of the cannula to sense counterforce exerted by the cavity wall after it has begun to be pierced by the trocar point and to sense relief of such counterforce when that distal end has cleared the cavity wall. The trigger sleeve is mechanically coupleable to the trip member to cause it to trip the latch in response to sensing relief of such counterforce.
摘要翻译：用于刺穿解剖腔壁以提供与空腔内部连通的安全套管针器具包括管状插管和具有尖锐穿刺点的细长套管针。套管针被安装成在套管内轴向往复运动，在抽出的静止位置之间，其中该点被套管的远端容纳在其中并被套管的远端屏蔽，并且突出位置中所述点暴露于插管的远端之外。收缩弹簧将套管针偏压到其撤回位置。闩锁将套针针闩锁在与缩回弹簧相对的突出位置处，并且跳闸部件可以跳动闩锁以解除套针针，从而允许套管针通过缩回弹簧移动到其撤回的休止位置。触发套筒形式的机械触发器安装在仪器内。其远端可定位在所述套针针头的极端和套管的远端之间，以在其开始被套针针刺穿之后感测由腔壁施加的反作用力，并且当该远端具有清空腔壁。触发套筒机械地联接到跳闸构件以使其响应于这种反作用力的感测减轻而使闩锁跳闸。

8. 发明授权

US5395034A Linear surgical stapling instrument 失效
标题翻译：线性手术吻合器械
公开(公告)号：US5395034A
公开(公告)日：1995-03-07
申请号：US947864
申请日：1992-09-21
申请人： William J. Allen , Joseph N. Logan , Jeffrey A. Stein , Paul C. DiCesare , Douglas M. Spranger , Paul J. Mulhauser
发明人： William J. Allen , Joseph N. Logan , Jeffrey A. Stein , Paul C. DiCesare , Douglas M. Spranger , Paul J. Mulhauser
IPC分类号： A61B17/068 , A61B17/072 , A61B19/00
CPC分类号： A61B17/07207 , A61B2017/07214 , A61B2017/07228 , A61B2090/0814
摘要： A linear surgical stapling instrument includes a magazine for holding a plurality of undeformed surgical staples, and an upper jaw carrying the magazine and having opposed distal and proximal ends. An anvil is formed with staple-deforming pockets, and a lower jaw carries the anvil and has opposing distal and proximal ends respectively configured to mate with the distal and proximal ends of the upper jaw thereby to place the magazine and the anvil in confronting relation. A staple driver is carried in the upper jaw for driving staples held therein toward the anvil. Further, the upper and lower jaws are configured such that, when their respective distal and proximal ends are mated, a gap exists between the jaws in an intermediate region between their respective distal and proximal ends. Finally, a pivotably mounted clamp bar joins the upper and lower jaws and when actuated compresses them together in the intermediate region thereby to narrow the gap and to increase the clamping pressure between the magazine and the anvil. The instrument also includes a blocking system that prevents the jaws from being remated, once having been mated and having had staples in the magazine driven toward the anvil. Still further, the instrument includes a coupling device for coupling the jaws and clamp bar together when the staple driver is actuated.
摘要翻译：线性外科缝合器械包括用于保持多个未变形的外科缝合钉的刀库，以及承载刀库并具有相对的远端和近端的上钳口。砧座形成有钉变形袋，下颚承载砧座，并且具有相对的远端和近端，分别构造成与上颚的远端和近端配合，从而将砧座与砧座置于面对关系。在上颚上承载有钉子驱动器，用于向砧座驱动被夹持在其中的订书钉。此外，上下钳口构造成使得当它们各自的远端和近端配合时，在它们各自的远端和近端之间的中间区域中的钳口之间存在间隙。最后，可枢转地安装的夹紧杆连接上下爪，并且当被致动时将它们压在一起在中间区域中，从而使间隙变窄，并增加料盒与砧座之间的夹紧压力。该仪器还包括一个阻挡系统，防止夹头被重新配合，一旦被配合并且已经将钉仓中的订书钉驱动到砧座。此外，该仪器包括联接装置，用于当订书钉驱动器致动时将夹爪和夹杆连接在一起。

9. 发明申请

US20110172686A1 Device For Engaging Tissue Having a Preexisting Opening 失效
标题翻译：用于使具有预先存在的开口的组织的装置
公开(公告)号：US20110172686A1
公开(公告)日：2011-07-14
申请号：US13073119
申请日：2011-03-28
申请人： Hanson S. Gifford, III , Lee R. Bolduc , Jeffrey A. Stein , Paul C. Dicesare , Peter F. Costa , William A. Holmes
发明人： Hanson S. Gifford, III , Lee R. Bolduc , Jeffrey A. Stein , Paul C. Dicesare , Peter F. Costa , William A. Holmes
IPC分类号： A61B17/11 , A61B17/064
CPC分类号： A61B17/12109 , A61B17/064 , A61B17/0643 , A61B17/11 , A61B17/115 , A61B17/12036 , A61B17/12045 , A61B17/12136 , A61B2017/00243 , A61B2017/0641 , A61B2017/1135 , A61B2017/12127 , A61F2002/30092 , A61F2210/0014
摘要： A system for performing an end-to-side vascular anastomosis. including an anastomosis device, an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery, particularly in port-access CABG surgery. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member, forming the attachment with the target vessel wall and a coupling member, forming the attachment with the bypass graft vessel. The anastomosis is completed by inserting the coupling member, with the graft vessel attached, into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple. A second aspect of the invention includes an anastomotic fitting, having an inner flange over which the graft vessel is everted and an outer flange which contacts the exterior surface of the target vessel. A tailored amount of compression applied by the inner and outer flanges grips the target vessel wall and creates a leak-proof seal between the graft vessel and the target vessel. A third aspect of the invention has a flange to which the graft vessel attaches, by everting the graft vessel over the flange, and a plurality of staple-like members which attach the flange and the everted end of the graft vessel to the wall of the target vessel to form the anastomosis
摘要翻译：用于进行端对侧血管吻合的系统。包括吻合装置，应用仪器和用于进行血管吻合的方法。该系统适用于在冠状动脉旁路手术中进行血管移植物和升主动脉之间的吻合，特别是在进入CABG手术中。本发明的第一方面包括血管吻合缝合物。第一构造具有两部分：锚定构件，与目标血管壁形成附件和联接构件，与旁路移植血管形成附件。通过将连接构件插入到锚定构件中来完成吻合。第二种结构将锚定构件和联接构件的功能结合成一体式吻合钉。本发明的第二方面包括一种吻合装置，其具有内部凸缘，移植物容器在其上延伸，外部凸缘接触目标血管的外表面。由内外法兰施加的定制的压缩量夹住目标血管壁，并在移植血管和靶血管之间产生防漏密封。本发明的第三方面具有凸缘，移植管通过使移植物容器穿过凸缘而附接到该凸缘上，以及多个钉状构件，其将该移植物容器的凸缘和脱出端附接到靶血管形成吻合

10. 发明授权

US06899718B2 Devices and methods for performing avascular anastomosis 失效
标题翻译：用于进行无血管吻合的装置和方法
公开(公告)号：US06899718B2
公开(公告)日：2005-05-31
申请号：US10830897
申请日：2004-04-23
申请人： Hanson S. Gifford, III , Lee R. Bolduc , Jeffrey A. Stein , Paul C. DiCesare , Peter F. Costa , William A. Holmes
发明人： Hanson S. Gifford, III , Lee R. Bolduc , Jeffrey A. Stein , Paul C. DiCesare , Peter F. Costa , William A. Holmes
IPC分类号： A61B17/00 , A61B17/064 , A61B17/11 , A61B17/115 , A61B17/12 , A61F2/00
CPC分类号： A61B17/12109 , A61B17/064 , A61B17/0643 , A61B17/11 , A61B17/115 , A61B17/12036 , A61B17/12045 , A61B17/12136 , A61B2017/00243 , A61B2017/0641 , A61B2017/1135 , A61B2017/12127 , A61F2002/30092 , A61F2210/0014
摘要： A system for performing an end-to-side vascular anastomosis, including an anastomosis device, an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery, particularly in port-access CABG surgery. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member, forming the attachment with the target vessel wall and a coupling member, forming the attachment with the bypass graft vessel. The anastomosis is completed by inserting the coupling member, with the graft vessel attached, into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple. A second aspect of the invention includes an anastomotic fitting, having an inner flange over which the graft vessel is everted and an outer flange which contacts the exterior surface of the target vessel. A tailored amount of compression applied by the inner and outer flanges grips the target vessel wall and creates a leak-proof seal between the graft vessel and the target vessel. A third aspect of the invention has a flange to which the graft vessel attaches, by everting the graft vessel over the flange, and a plurality of staple-like members which attach the flange and the everted end of the graft vessel to the wall of the target vessel to form the anastomosis
摘要翻译：一种用于执行端对侧血管吻合的系统，包括吻合装置，应用仪器和用于进行血管吻合的方法。该系统适用于在冠状动脉旁路手术中进行血管移植物和升主动脉之间的吻合，特别是在进入CABG手术中。本发明的第一方面包括血管吻合缝合物。第一构造具有两部分：锚定构件，与目标血管壁形成附件和联接构件，与旁路移植血管形成附件。通过将连接构件插入到锚定构件中来完成吻合。第二种结构将锚定构件和联接构件的功能结合成一体式吻合钉。本发明的第二方面包括一种吻合装置，其具有内部凸缘，移植物容器在其上延伸，外部凸缘接触目标血管的外表面。由内外法兰施加的定制的压缩量夹住目标血管壁，并在移植血管和靶血管之间产生防漏密封。本发明的第三方面具有凸缘，移植管通过使移植物容器穿过凸缘而附接到该凸缘上，以及多个钉状构件，其将该移植物容器的凸缘和脱出端附接到靶血管形成吻合

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