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1. 发明授权

US06682541B1 Devices and methods for performing a vascular anastomosis 失效
标题翻译：用于进行血管吻合的装置和方法
公开(公告)号：US06682541B1
公开(公告)日：2004-01-27
申请号：US10244366
申请日：2002-09-16
申请人： Hanson S. Gifford, III , Lee R. Bolduc , Jeffrey A. Stein , Paul C. DiCesare , Peter F. Costa , William A. Holmes
发明人： Hanson S. Gifford, III , Lee R. Bolduc , Jeffrey A. Stein , Paul C. DiCesare , Peter F. Costa , William A. Holmes
IPC分类号： A61B1711
CPC分类号： A61B17/12109 , A61B17/064 , A61B17/0643 , A61B17/11 , A61B17/115 , A61B17/12036 , A61B17/12045 , A61B17/12136 , A61B2017/00243 , A61B2017/0641 , A61B2017/1135 , A61B2017/12127 , A61F2002/30092 , A61F2210/0014
摘要： A system for performing an end-to-side vascular anastomosis, including an anastomosis device, an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery, particularly in port-access CABG surgery. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member, forming the attachment with the target vessel wall and a coupling member, forming the attachment with the bypass graft vessel. The anastomosis is completed by inserting the coupling member, with the graft vessel attached, into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple. A second aspect of the invention includes an anastomotic fitting, having an inner flange over which the graft vessel is everted and an outer flange which contacts the exterior surface of the target vessel. A tailored amount of compression applied by the inner and outer flanges grips the target vessel wall and creates a leak-proof seal between the graft vessel and the target vessel. A third aspect of the invention has a flange to which the graft vessel attaches, by everting the graft vessel over the flange, and a plurality of staple-like members which attach the flange and the everted end of the graft vessel to the wall of the target vessel to form the anastomosis.
摘要翻译：一种用于执行端对侧血管吻合的系统，包括吻合装置，应用仪器和用于进行血管吻合的方法。该系统适用于在冠状动脉旁路手术中进行血管移植物和升主动脉之间的吻合，特别是在进入CABG手术中。本发明的第一方面包括血管吻合缝合物。第一构造具有两部分：锚定构件，与目标血管壁形成附件和联接构件，与旁路移植血管形成附件。通过将连接构件插入到锚定构件中来完成吻合。第二种结构将锚定构件和联接构件的功能结合成一体式吻合钉。本发明的第二方面包括一种吻合装置，其具有内部凸缘，移植物容器在其上延伸，外部凸缘接触目标血管的外表面。由内外法兰施加的定制的压缩量夹住目标血管壁，并在移植血管和靶血管之间产生防漏密封。本发明的第三方面具有凸缘，移植管通过使移植物容器穿过凸缘而附接到该凸缘上，以及多个钉状构件，其将该移植物容器的凸缘和脱出端附接到靶血管形成吻合。

2. 发明授权

US06565582B2 Devices and methods for performing a vascular anastomosis 有权
公开(公告)号：US06565582B2
公开(公告)日：2003-05-20
申请号：US10174694
申请日：2002-06-19
申请人： Hanson S. Gifford, III , Lee R. Bolduc , Jeffrey A. Stein , Paul C. DiCesare , Peter F. Costa , William A. Holmes
发明人： Hanson S. Gifford, III , Lee R. Bolduc , Jeffrey A. Stein , Paul C. DiCesare , Peter F. Costa , William A. Holmes
IPC分类号： A61B1711
CPC分类号： A61B17/12109 , A61B17/064 , A61B17/0643 , A61B17/11 , A61B17/115 , A61B17/12036 , A61B17/12045 , A61B17/12136 , A61B2017/00243 , A61B2017/0641 , A61B2017/1135 , A61B2017/12127 , A61F2002/30092 , A61F2210/0014
摘要： A system for performing an end-to-side vascular anastomosis, including an anastomosis device, an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery, particularly in port-access CABG surgery. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member, forming the attachment with the target vessel wall and a coupling member, forming the attachment with the bypass graft vessel. The anastomosis is completed by inserting the coupling member, with the graft vessel attached, into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple. A second aspect of the invention includes an anastomotic fitting, having an inner flange over which the graft vessel is everted and an outer flange which contacts the exterior surface of the target vessel. A tailored amount of compression applied by the inner and outer flanges grips the target vessel wall and creates a leak-proof seal between the graft vessel and the target vessel. A third aspect of the invention has a flange to which the graft vessel attaches, by everting the graft vessel over the flange, and a plurality of staple-like members which attach the flange and the everted end of the graft vessel to the wall of the target vessel to form the anastomosis.

3. 发明授权

US06491704B2 Devices and methods for performing a vascular anastomosis 有权
公开(公告)号：US06491704B2
公开(公告)日：2002-12-10
申请号：US09915629
申请日：2001-07-26
申请人： Hanson S. Gifford, III , Lee R. Bolduc , Jeffrey A. Stein , Paul C. DiCesare , Peter F. Costa , William A. Holmes
发明人： Hanson S. Gifford, III , Lee R. Bolduc , Jeffrey A. Stein , Paul C. DiCesare , Peter F. Costa , William A. Holmes
IPC分类号： A61B1708
CPC分类号： A61B17/12109 , A61B17/064 , A61B17/0643 , A61B17/11 , A61B17/115 , A61B17/12036 , A61B17/12045 , A61B17/12136 , A61B2017/00243 , A61B2017/0641 , A61B2017/1135 , A61B2017/12127 , A61F2002/30092 , A61F2210/0014
摘要： A system for performing an end-to-side vascular anastomosis, including an anastomosis device, an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery, particularly in port-access CABG surgery. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member, forming the attachment with the target vessel wall and a coupling member, forming the attachment with the bypass graft vessel. The anastomosis is completed by inserting the coupling member, with the graft vessel attached, into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple. A second aspect of the invention includes an anastomotic fitting, having an inner flange over which the graft vessel is everted and an outer flange which contacts the exterior surface of the target vessel. A tailored amount of compression applied by the inner and outer flanges grips the target vessel wall and creates a leak-proof seal between the graft vessel and the target vessel. A third aspect of the invention has a flange to which the graft vessel attaches, by everting the graft vessel over the flange, and a plurality of staple-like members which attach the flange and the everted end of the graft vessel to the wall of the target vessel to form the anastomosis.

4. 发明授权

US5904697A Devices and methods for performing a vascular anastomosis 有权
公开(公告)号：US5904697A
公开(公告)日：1999-05-18
申请号：US166338
申请日：1998-10-05
申请人： Hanson S. Gifford, III , Lee R. Bolduc , Jeffrey A. Stein , Paul C. DiCesare , Peter F. Costa , William A. Holmes
发明人： Hanson S. Gifford, III , Lee R. Bolduc , Jeffrey A. Stein , Paul C. DiCesare , Peter F. Costa , William A. Holmes
IPC分类号： A61B17/00 , A61B17/064 , A61B17/11 , A61B17/115 , A61B17/12 , A61F2/00
CPC分类号： A61B17/12109 , A61B17/064 , A61B17/115 , A61B17/12036 , A61B17/12045 , A61B17/12136 , A61B17/0643 , A61B17/11 , A61B2017/00243 , A61B2017/0641 , A61B2017/1135 , A61B2017/12127 , A61F2002/30092 , A61F2210/0014
摘要： A system for performing an end-to-side vascular anastomosis, including an anastomosis device, an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery, particularly in port-access CABG surgery. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member, forming the attachment with the target vessel wall and a coupling member, forming the attachment with the bypass graft vessel. The anastomosis is completed by inserting the coupling member, with the graft vessel attached, into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple. A second aspect of the invention includes an anastomotic fitting, having an inner flange over which the graft vessel is everted and an outer flange which contacts the exterior surface of the target vessel. A tailored amount of compression applied by the inner and outer flanges grips the target vessel wall and creates a leak-proof seal between the graft vessel and the target vessel. A third aspect of the invention has a flange to which the graft vessel attaches, by everting the graft vessel over the flange, and a plurality of staple-like members which attach the flange and the everted end of the graft vessel to the wall of the target vessel to form the anastomosis.

5. 发明授权

US5817113A Devices and methods for performing a vascular anastomosis 失效
公开(公告)号：US5817113A
公开(公告)日：1998-10-06
申请号：US789327
申请日：1997-01-23
申请人： Hanson S. Gifford, III , Lee R. Bolduc , Jeffrey A. Stein , Paul C. DiCesare , Peter F. Costa , William A. Holmes
发明人： Hanson S. Gifford, III , Lee R. Bolduc , Jeffrey A. Stein , Paul C. DiCesare , Peter F. Costa , William A. Holmes
IPC分类号： A61B17/00 , A61B17/064 , A61B17/068 , A61B17/11 , A61B17/115 , A61B17/12 , A61F2/00
CPC分类号： A61B17/068 , A61B17/064 , A61B17/115 , A61B17/12036 , A61B17/12045 , A61B17/12109 , A61B17/12136 , A61B17/0643 , A61B17/11 , A61B2017/00243 , A61B2017/0641 , A61B2017/0647 , A61B2017/1103 , A61B2017/1107 , A61B2017/1135 , A61B2017/12127 , A61F2002/30092 , A61F2210/0014
摘要： A system for performing an end-to-side vascular anastomosis, including an anastomosis device, an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery, particularly in port-access CABG surgery. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member, forming the attachment with the target vessel wall and a coupling member, forming the attachment with the bypass graft vessel. The anastomosis is completed by inserting the coupling member, with the graft vessel attached, into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple. A second aspect of the invention includes an anastomotic fitting, having an inner flange over which the graft vessel is everted and an outer flange which contacts the exterior surface of the target vessel. A tailored amount of compression applied by the inner and outer flanges grips the target vessel wall and creates a leak-proof seal between the graft vessel and the target vessel. A third aspect of the invention has a flange to which the graft vessel attaches, by everting the graft vessel over the flange, and a plurality of staple-like members which attach the flange and the everted end of the graft vessel to the wall of the target vessel to form the anastomosis.

6. 发明授权

US5474539A Trocar with retracting tip 失效
标题翻译：套筒带回缩尖端
公开(公告)号：US5474539A
公开(公告)日：1995-12-12
申请号：US15349
申请日：1993-02-08
申请人： Peter F. Costa , William A. Holmes , Frederic H. Moll
发明人： Peter F. Costa , William A. Holmes , Frederic H. Moll
IPC分类号： A61B17/34 , A61B19/00 , A61M5/178
CPC分类号： A61B17/3496 , A61B2090/08021
摘要： A trocar assembly consisting of a trocar tube subassembly and a separate interengageable trocar body subassembly is provided. The trocar body subassembly includes an elongated obturator having a sharp pointed tip which is normally housed within an elongated tube of the trocar tube subassembly. The obturator is extendable from a retracted position within the tube wherein the tip is recessed from the tube end to an operative position forward of said tube end and outside the tube. By manually advancing the trocar assembly against a body wall, the resisting force locks the obturator in the operative position. Relaxation of the force incident to passing through the body wall causes the obturator to be automatically unlocked and retracted to its initial position with the tip positioned protectively within the tube, thereby protecting body tissues and organs from being damaged by the tip when it enters a body cavity beyond the wall.
摘要翻译：提供了一种套管针组件，其由套管针管子组件和单独的相互接合的套针针体组件组成。套针针体组件包括细长的闭塞器，其具有通常容纳在套管针子组件的细长管内的尖锐尖端。闭塞器可从管中的缩回位置延伸，其中尖端从管端凹入到管末端和管外的操作位置。通过将套管针组件手动地推靠在身体壁上，阻力将闭塞器锁定在操作位置。通过身体壁的力的放松使得闭孔器自动解锁并缩回到其初始位置，其中尖端保护性地定位在管内，从而保护身体组织和器官在进入身体时被尖端损坏超过墙壁的空腔。

7. 发明授权

US4931042A Trocar assembly with improved latch 失效
标题翻译：具有改进闩锁的套管针组件
公开(公告)号：US4931042A
公开(公告)日：1990-06-05
申请号：US113013
申请日：1987-10-26
申请人： William A. Holmes , Peter F. Costa
发明人： William A. Holmes , Peter F. Costa
IPC分类号： A61B17/34 , A61B19/00
CPC分类号： A61B17/3496 , A61B2090/08021
摘要： A trocar assembly comprising an elongate trocar obturator having a piercing tip at its front end, an elongate trocar tube in which the obturator is housed, and a tubular protective shield mounted concentrically around the obturator between a normally extended position in which the obturator tip is covered and a retracted position in which the obturator tip is exposed. Further included is a spring acting on the protective shield, whereby the shield is forced to the retracted position to expose the piercing tip when the trocar is being inserted through the wall of a body cavity and is biased by the spring to the extended position to shield the piercing tip once the trocar has pierced the wall. A protrusion extends radially from the shield. A leaf spring element has one end anchored relative to the obturator and a second end biased to contact the protrusion in a manner preventing movement of the shield from the extended position toward the retracted position when the element is in contact with the protrusion. A trigger, coupled to the leaf spring member is shiftable between a lock position and a release position. When the trigger is in the lock position, the shield can not be moved from the extended position. When it is in the release position, the shield can travel to the retracted position. When it moves to the retracted position, it disengages the trigger so that when the shield returns to the extended position, it locks in place, even through the trigger is in the release position.
摘要翻译：一种套管针组件，其包括在其前端具有穿刺尖端的细长套管针闭塞器，其中容纳所述闭孔器的细长套管针管，以及围绕所述闭孔器同心地安装在所述闭塞器尖端被覆盖的正常延伸位置的管状保护罩以及收缩位置，其中闭嘴尖露出。进一步包括作用在保护屏蔽上的弹簧，由此当套管针被插入穿过体腔的壁时，屏蔽件被迫到缩回位置以暴露穿刺尖端，并且被弹簧偏压到延伸位置以屏蔽一旦套管针刺穿了墙壁，穿刺尖端。突起从屏蔽件径向延伸。板簧元件具有相对于闭孔器锚定的一端，以及当元件与突起接触时，被阻止以防止屏蔽件从延伸位置朝向缩回位置运动的方式接触突起的第二端。联接到板簧构件的触发器可以在锁定位置和释放位置之间移动。当触发器处于锁定位置时，屏蔽不能从伸出位置移动。当其处于释放位置时，屏蔽件可以行进到缩回位置。当它移动到缩回位置时，它使触发器脱离，使得当屏蔽件返回到延伸位置时，其锁定就位，即使通过触发器处于释放位置。

8. 发明授权

US4595126A Portable water container with easily-replaceable liner 失效
标题翻译：便携式水箱，容易更换的内胆
公开(公告)号：US4595126A
公开(公告)日：1986-06-17
申请号：US410420
申请日：1982-08-23
申请人： William A. Holmes
发明人： William A. Holmes
IPC分类号： A45F3/16 , B65D37/00 , A45F3/20 , F16L5/00
CPC分类号： A45F3/16 , Y10T24/44034
摘要： A portable water container is disclosed having an inner bag formed of a flexible water impermeable sheet and an outer protective covering for the bag formed of a wear-resistant fabric; a tubular drain and fill conduit mounted in aligned openings in the bag and covering; and a releasable seal clamping the sheet forming the inner bag in a watertight sealed connection for sealing the conduit to and in flow communication with such bag; and a clamp securing the conduit in a load-bearing attachment to the covering.
摘要翻译：公开了一种便携式水容器，其具有由柔性不透水片形成的内袋和用于由耐磨织物形成的袋的外保护罩; 安装在袋和盖中的对齐开口中的管状排出和填充导管; 以及可释放的密封件，其将形成所述内袋的所述片材紧固在水密密封的连接中，以将所述导管密封并与所述袋子流动连通; 以及将导管固定在覆盖物的承载附件中的夹具。

9. 发明授权

US07112211B2 Devices and methods for performing avascular anastomosis 有权
标题翻译：用于进行无血管吻合的装置和方法
公开(公告)号：US07112211B2
公开(公告)日：2006-09-26
申请号：US10339434
申请日：2003-01-09
申请人： Hanson S. Gifford, III , Lee R. Bolduc , Jeffrey A. Stein , Paul C. DiCesare , Peter F. Costa , William A. Holmes
发明人： Hanson S. Gifford, III , Lee R. Bolduc , Jeffrey A. Stein , Paul C. DiCesare , Peter F. Costa , William A. Holmes
IPC分类号： A61B17/11
CPC分类号： A61B17/12109 , A61B17/064 , A61B17/0643 , A61B17/11 , A61B17/115 , A61B17/12036 , A61B17/12045 , A61B17/12136 , A61B2017/00243 , A61B2017/0641 , A61B2017/1135 , A61B2017/12127 , A61F2002/30092 , A61F2210/0014
摘要： A system for performing an end-to-side vascular anastomosis. including an anastomosis device, an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery, particularly in port-access CABG surgery. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member, forming the attachment with the target vessel wall and a coupling member, forming the attachment with the bypass graft vessel. The anastomosis is completed by inserting the coupling member, with the graft vessel attached, into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple. A second aspect of the invention includes an anastomotic fitting, having an inner flange over which the graft vessel is everted and an outer flange which contacts the exterior surface of the target vessel. A tailored amount of compression applied by the inner and outer flanges grips the target vessel wall and creates a leak-proof seal between the graft vessel and the target vessel. A third aspect of the invention has a flange to which the graft vessel attaches, by everting the graft vessel over the flange, and a plurality of staple-like members which attach the flange and the everted end of the graft vessel to the wall of the target vessel to form the anastomosis.
摘要翻译：用于进行端对侧血管吻合的系统。包括吻合装置，应用仪器和用于进行血管吻合的方法。该系统适用于在冠状动脉旁路手术中进行血管移植物和升主动脉之间的吻合，特别是在进入CABG手术中。本发明的第一方面包括血管吻合缝合物。第一构造具有两部分：锚定构件，与目标血管壁形成附件和联接构件，与旁路移植血管形成附件。通过将连接构件插入到锚定构件中来完成吻合。第二种结构将锚定构件和联接构件的功能结合成一体式吻合钉。本发明的第二方面包括一种吻合装置，其具有内部凸缘，移植物容器在其上延伸，外部凸缘接触目标血管的外表面。由内外法兰施加的定制的压缩量夹住目标血管壁，并在移植血管和靶血管之间产生防漏密封。本发明的第三方面具有凸缘，移植管通过使移植物容器穿过凸缘而附接到该凸缘上，以及多个钉状构件，其将该移植物容器的凸缘和脱出端附接到靶血管形成吻合。

10. 发明授权

US06984238B2 Devices and methods for performing avascular anastomosis 失效
公开(公告)号：US06984238B2
公开(公告)日：2006-01-10
申请号：US10830952
申请日：2004-04-23
申请人： Hanson S. Gifford, III , Lee R. Bolduc , Jeffrey A. Stein , Paul C. DiCesare , Peter F. Costa , William A. Holmes
发明人： Hanson S. Gifford, III , Lee R. Bolduc , Jeffrey A. Stein , Paul C. DiCesare , Peter F. Costa , William A. Holmes
IPC分类号： A61B17/11
CPC分类号： A61B17/12109 , A61B17/064 , A61B17/0643 , A61B17/11 , A61B17/115 , A61B17/12036 , A61B17/12045 , A61B17/12136 , A61B2017/00243 , A61B2017/0641 , A61B2017/1135 , A61B2017/12127 , A61F2002/30092 , A61F2210/0014
摘要： A system for performing an end-to-side vascular anastomosis. including an anastomosis device, an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery, particularly in port-access CABG surgery. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member, forming the attachment with the target vessel wall and a coupling member, forming the attachment with the bypass graft vessel. The anastomosis is completed by inserting the coupling member, with the graft vessel attached, into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple. A second aspect of the invention includes an anastomotic fitting, having an inner flange over which the graft vessel is everted and an outer flange which contacts the exterior surface of the target vessel. A tailored amount of compression applied by the inner and outer flanges grips the target vessel wall and creates a leak-proof seal between the graft vessel and the target vessel. A third aspect of the invention has a flange to which the graft vessel attaches, by everting the graft vessel over the flange, and a plurality of staple-like members which attach the flange and the everted end of the graft vessel to the wall of the target vessel to form the anastomosis

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