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1. 发明授权

US08039450B2 Boron-containing small molecules as anti-inflammatory agents 有权
标题翻译：含硼的小分子作为抗炎剂
公开(公告)号：US08039450B2
公开(公告)日：2011-10-18
申请号：US12399015
申请日：2009-03-05
申请人： Tsutomu Akama , Yong-Kang Zhang , Charles Z. Ding , Jacob J. Plattner , Kirk R. Maples , Yvonne Freund , Virginia Sanders , Yi Xia , Stephen J. Baker , James A. Nieman , Xiaosong Lu , Marcelo Sales , Rashmi Sharma , Rajeshwar Singh , Robert Jacobs , Daitao Chen , Michael Richard Kevin Alley
发明人： Tsutomu Akama , Yong-Kang Zhang , Charles Z. Ding , Jacob J. Plattner , Kirk R. Maples , Yvonne Freund , Virginia Sanders , Yi Xia , Stephen J. Baker , James A. Nieman , Xiaosong Lu , Marcelo Sales , Rashmi Sharma , Rajeshwar Singh , Robert Jacobs , Daitao Chen , Michael Richard Kevin Alley
IPC分类号： A61K31/69 , C07F5/04
CPC分类号： C07F5/025 , A61K31/69 , C07F5/04 , Y02A50/411
摘要： Compounds and methods of treating anti-inflammatory conditions are disclosed.
摘要翻译：公开了治疗抗炎症状的化合物和方法。

2. 发明授权

US09493489B2 Boron-containing small molecules as anti-protozoal agents 有权
标题翻译：含硼的小分子作为抗原生动物
公开(公告)号：US09493489B2
公开(公告)日：2016-11-15
申请号：US13062450
申请日：2009-10-15
申请人： Robert Jacobs , Matthew Orr , Stephen Wring , Daitao Chen , Huchen Zhou , Dazhong Ding , Yiqing Feng , Long Yi , Vincent S. Hernandez , Yong-Kang Zhang , Jacob J. Plattner
发明人： Robert Jacobs , Matthew Orr , Stephen Wring , Daitao Chen , Huchen Zhou , Dazhong Ding , Yiqing Feng , Long Yi , Vincent S. Hernandez , Yong-Kang Zhang , Jacob J. Plattner
IPC分类号： A61K31/69 , C07F5/02
CPC分类号： C07F5/025 , A61K31/69 , Y02A50/409 , Y02A50/411 , Y02A50/414 , Y02A50/415
摘要： This invention provides, among other things, novel compounds useful for treating protozoal infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.
摘要翻译：本发明尤其提供了可用于治疗原生动物感染的新化合物，含有这些化合物的药物组合物，以及这些化合物与至少一种另外的治疗有效药物的组合。

3. 发明申请

US20110207702A1 BORON-CONTAINING SMALL MOLECULES AS ANTI-PROTOZOAL AGENTS 有权
标题翻译：含有BORON的小分子作为抗真菌剂
公开(公告)号：US20110207702A1
公开(公告)日：2011-08-25
申请号：US13062450
申请日：2009-10-15
申请人： Robert Jacobs , Matthew Orr , Stephen Wring , Daitao Chen , Huchen Zhou , Dazhong Ding , Yiqing Feng , Long Yi , Vincent S. Hernandez , Yong-Kang Zhang , Jacob J. Plattner
发明人： Robert Jacobs , Matthew Orr , Stephen Wring , Daitao Chen , Huchen Zhou , Dazhong Ding , Yiqing Feng , Long Yi , Vincent S. Hernandez , Yong-Kang Zhang , Jacob J. Plattner
IPC分类号： A61K31/69 , C07F5/02 , C12N1/10 , A61P33/02
CPC分类号： C07F5/025 , A61K31/69 , Y02A50/409 , Y02A50/411 , Y02A50/414 , Y02A50/415
摘要： This invention provides, among other things, novel compounds useful for treating protozoal infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.
摘要翻译：本发明尤其提供了可用于治疗原生动物感染的新化合物，含有这些化合物的药物组合物，以及这些化合物与至少一种另外的治疗有效药物的组合。

4. 发明授权

US09440994B2 Boron containing small molecules as antiprotozoal agents 有权
标题翻译：含有小分子的硼作为抗原虫剂
公开(公告)号：US09440994B2
公开(公告)日：2016-09-13
申请号：US12852351
申请日：2010-08-06
申请人： Daitao Chen , Matthew Orr , Jessica Sligar , Robert Jacobs , Jacob J. Plattner
发明人： Daitao Chen , Matthew Orr , Jessica Sligar , Robert Jacobs , Jacob J. Plattner
IPC分类号： C07F5/02
CPC分类号： C07F5/025 , A01N55/08 , A61K31/69
摘要： This invention provides, among other things, novel compounds useful for treating protozoal infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent. The exemplary compounds have the following formula: wherein X is selected from the group consisting of substituted phenyl, substituted or unsubstituted heteroaryl and unsubstituted cycloalkyl; R3a is selected from the group consisting of H, unsubstituted C1 or C2 or C3 or C4 or C5 or C6 alkyl and unsubstituted C3 or C4 or C5 or C6 cycloalkyl; R3b is selected from the group consisting of H, unsubstituted C1 or C2 or C3 or C4 or C5 or C6 alkyl and unsubstituted C3 or C4 or C5 or C6 cycloalkyl; with the proviso that R3a and R3b, along with the atom to which they are attached, are optionally joined to form a 3 or 4 or 5 or 6 membered ring, with the proviso that R3a and R3b cannot both be H, or a salt thereof.

5. 发明申请

US20110190235A1 BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS 有权
公开(公告)号：US20110190235A1
公开(公告)日：2011-08-04
申请号：US12852351
申请日：2010-08-06
申请人： Daitao Chen , Matthew Orr , Jessica Sligar , Robert Jacobs , Jacob J. Plattner
发明人： Daitao Chen , Matthew Orr , Jessica Sligar , Robert Jacobs , Jacob J. Plattner
IPC分类号： A61K31/69 , C07F5/04 , A61P33/02
CPC分类号： C07F5/025 , A01N55/08 , A61K31/69
摘要： This invention provides, among other things, novel compounds useful for treating protozoal infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.

6. 发明授权

US09781064B2 Method and system for creating and distributing electronic postcards 有权
公开(公告)号：US09781064B2
公开(公告)日：2017-10-03
申请号：US14447451
申请日：2014-07-30
申请人： Robert Jacobs , Eric D. Kroll
发明人： Robert Jacobs , Eric D. Kroll
IPC分类号： G06F15/16 , H04L12/58
CPC分类号： H04L51/10
摘要： Method and system for creating and distributing professional quality electronic postcards are provided. An accessible library of numerous photographs/videos taken by professionals is maintained, for example, on a app or website. Access to the app or website can be accomplished using any suitable input device, for example smart phones, tablets, laptops, computers etc. Following a series of simple steps, users select from an assortment of images, videos, photos, messages, etc., to create an electronic postcard. Users have their own pages on the app or website, where sent and received electronic postcards are stored. A simple method for creating albums from the user's electronic postcards is also provided.

7. 发明申请

US20090170851A1 Chroman Compounds 审中-公开
标题翻译：色甘酸化合物
公开(公告)号：US20090170851A1
公开(公告)日：2009-07-02
申请号：US12403553
申请日：2009-03-13
申请人： Peter Bernstein , Daniel Hill , David Nugiel , Edward Pierson , Ashokkumar Shenvi , Robert Jacobs
发明人： Peter Bernstein , Daniel Hill , David Nugiel , Edward Pierson , Ashokkumar Shenvi , Robert Jacobs
IPC分类号： A61K31/5377 , A61P25/22
CPC分类号： C07D311/66
摘要： Compounds according to Formula (I): wherein R1, R2, R3, and R4 are as defined in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
摘要翻译：根据式（I）的化合物：其中R 1，R 2，R 3和R 4如本说明书中所定义，药学上可接受的盐，制备方法，药物组合物及其使用方法。

8. 发明申请

US20070191422A1 Nicotinic acetylcholine receptor ligands 审中-公开
标题翻译：烟碱乙酰胆碱受体配体
公开(公告)号：US20070191422A1
公开(公告)日：2007-08-16
申请号：US10583581
申请日：2004-12-20
申请人： Glen Ernst , Robert Jacobs , Eifion Phillips
发明人： Glen Ernst , Robert Jacobs , Eifion Phillips
IPC分类号： A61K31/4745 , C07D453/02
CPC分类号： C07D453/02
摘要： Compounds of formula (I), wherein D, Ar1, E and Ar2 are as defined in the specification, processes for preparing them, pharmaceutical compositions containing them and their use in therapy, especially in the treatment or prophylaxis of psychotic and intellectual impairment disorders.
摘要翻译：式（I）化合物，其中D，Ar1，E和Ar2如本说明书中所定义，其制备方法，含有它们的药物组合物及其在治疗中的用途，特别是治疗或预防精神病和智力障碍障碍。

9. 发明申请

US20070006146A1 Systems and apparatus for enhanced mobile computing platforms 审中-公开
标题翻译：用于增强移动计算平台的系统和设备
公开(公告)号：US20070006146A1
公开(公告)日：2007-01-04
申请号：US11165815
申请日：2005-06-24
申请人： Wah Kwong , Prosenjit Ghosh , Katie Mills , Jim Trethewey , Robert Jacobs , Tim Nguyen , Asim Sadiq , Shreekant Thakkar , Murali Veeramoney , Truong Phan
发明人： Wah Kwong , Prosenjit Ghosh , Katie Mills , Jim Trethewey , Robert Jacobs , Tim Nguyen , Asim Sadiq , Shreekant Thakkar , Murali Veeramoney , Truong Phan
IPC分类号： G06F9/44
CPC分类号： G06F1/18
摘要： According to some embodiments, systems and apparatus for enhanced mobile computing platforms are provided. For example, an apparatus or system may comprise a universal computational package, comprising a processor, a memory coupled to the processor, a plurality of instructions stored in the memory directed to at least one specific use of the universal computational package, and a plurality of interface controllers coupled to the processor, wherein each of the plurality of interface controllers is operable to cause the processor to execute the plurality of stored instructions in accordance with the presence of a use-specific user interface cover associated with the at least one specific use of the universal computational package.
摘要翻译：根据一些实施例，提供了用于增强的移动计算平台的系统和装置。例如，装置或系统可以包括通用计算包，包括处理器，耦合到处理器的存储器，存储在存储器中的多个指令，用于至少一个特定使用的通用计算包，以及多个接口控制器，其耦合到所述处理器，其中所述多个接口控制器中的每一个可操作以使得所述处理器根据与所述至少一个特定使用相关联的使用特定用户界面覆盖的存在来执行所述多个存储的指令通用的计算包。

10. 发明授权

US5860653A Method and apparatus for playing a word game 失效
标题翻译：播放文字游戏的方法和装置
公开(公告)号：US5860653A
公开(公告)日：1999-01-19
申请号：US441493
申请日：1995-05-15
申请人： Robert Jacobs
发明人： Robert Jacobs
IPC分类号： G06Q10/10 , A63F9/22
CPC分类号： G06Q10/107
摘要： Apparatus and method for playing an anagram-type game in a game show or computer game format. One or more anagrams, each comprised of scrambled letters, are displayed on a gameboard. At least one object of the game is to guess the unscrambled solution to each anagram. When correctly guessed, the letters are moved from their scrambled configuration to their unscrambled configuration. An ultimate solution to the puzzle is preferrably revealed by some of the letters of the collective unscrambled anagrams which are moved into a predetermined alignment. Several means are included for making it easier to view, study and follow the progress of the game such as moving each letter along a path, leaving outlines of the letters in their initial positions, and indicating which anagram is to be guessed by a player.
摘要翻译：用于在游戏节目或计算机游戏格式中播放卦式游戏的装置和方法。每个包括乱码的一个或多个卦语显示在游戏板上。游戏的至少一个对象是猜测每个卦语的解扰解。当被正确猜测时，这些字母从他们的加扰配置移动到他们的未加扰配置。拼图的最终解决方案最好是通过集合的未加扰的卦语的一些字母来显示，这些字母被移动到预定的对齐位置。包括了几种手段，使其更容易查看，学习和跟踪游戏的进展，例如沿着路径移动每个字母，将字母的轮廓留在其初始位置，并指示玩家猜测哪个卦语。

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