专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2014009438A2 MYCOBACTERIAL ANTIGEN VACCINE 审中-公开
公开(公告)号：WO2014009438A2
公开(公告)日：2014-01-16
申请号：PCT/EP2013/064624
申请日：2013-07-10
申请人： TRANSGENE SA
发明人： TUPIN, Emmanuel , MICOL, Romain , COUPET, Charles Antoine , INCHAUPSE, Geneviève , GOUANVIC, Marie , SILVESTRE, Nathalie , MARCHAND, Jean-Baptiste , BENY, Cécile
IPC分类号： A61K39/04
CPC分类号： A61K39/04 , A61K2039/51 , A61K2039/53 , C07K14/35 , C07K16/1289 , C07K2319/00 , C07K2319/40
摘要： The present invention relates generally to immunogenic combinations comprising at least five antigens of a Mycobacterium species as well as fusion thereof and nucleic acid molecules encoding such combined antigens and fusion. The present invention also relates to nucleic acid molecules, vectors, host cells and compositions comprising or encoding said combinations of mycobacterial antigens and fusion polypeptides as well as to methods for recombinantly producing them. The present invention also relates to methods of using said combinations of mycobacterial antigens, fusion polypeptides, vectors, host cells, compositions particularly for inducing or stimulating an immune response against a Mycobacterium infection or any disease caused by or associated with a Mycobacterium infection. The present invention also concerns antibodies directed to such mycobacterial antigens and fusion polypeptides that can be used in the diagnosis of a Mycobacterium infection and method of detection as well as kits of reagent comprising said combinations of mycobacterial antigens, fusion polypeptides, vectors, host cells, compositions or antibodies.
摘要翻译：本发明一般涉及包含至少五种分枝杆菌属物种的抗原及其融合物的免疫原性组合，以及编码这种组合抗原和融合物的核酸分子。本发明还涉及包含或编码所述分枝杆菌抗原和融合多肽组合的核酸分子，载体，宿主细胞和组合物，以及用于重组产生它们的方法。本发明还涉及使用所述分枝杆菌抗原，融合多肽，载体，宿主细胞，组合物特别用于诱导或刺激针对分枝杆菌感染或由分枝杆菌感染引起或与其相关的任何疾病的免疫应答的组合的方法。本发明还涉及可用于诊断分枝杆菌感染的此类分枝杆菌抗原和融合多肽的抗体和检测方法以及包含所述分枝杆菌抗原组合，融合多肽，载体，宿主细胞，组合物或抗体。

2. 发明公开

EP2872172A2 MYCOBACTERIAL ANTIGEN VACCINE 审中-公开
标题翻译： IMPFSTOFF MIT EINEM MYKOBAKTERIELLEN ANTIGEN
公开(公告)号：EP2872172A2
公开(公告)日：2015-05-20
申请号：EP13735275.3
申请日：2013-07-10
申请人： Transgene SA
发明人： TUPIN, Emmanuel , MICOL, Romain , COUPET, Charles Antoine , INCHAUPSE, Geneviève , GOUANVIC, Marie , SILVESTRE, Nathalie , MARCHAND, Jean-Baptiste , BENY, Cécile
IPC分类号： A61K39/04
CPC分类号： A61K39/04 , A61K2039/51 , A61K2039/53 , C07K14/35 , C07K16/1289 , C07K2319/00 , C07K2319/40
摘要： The present invention relates generally to immunogenic combinations comprising at least five antigens of a Mycobacterium species as well as fusion thereof and nucleic acid molecules encoding such combined antigens and fusion. The present invention also relates to nucleic acid molecules, vectors, host cells and compositions comprising or encoding said combinations of mycobacterial antigens and fusion polypeptides as well as to methods for recombinantly producing them. The present invention also relates to methods of using said combinations of mycobacterial antigens, fusion polypeptides, vectors, host cells, compositions particularly for inducing or stimulating an immune response against a Mycobacterium infection or any disease caused by or associated with a Mycobacterium infection. The present invention also concerns antibodies directed to such mycobacterial antigens and fusion polypeptides that can be used in the diagnosis of a Mycobacterium infection and method of detection as well as kits of reagent comprising said combinations of mycobacterial antigens, fusion polypeptides, vectors, host cells, compositions or antibodies.
摘要翻译：本发明一般涉及包含分枝杆菌属物种的至少五种抗原及其融合物和编码这种组合抗原和融合物的核酸分子的免疫原性组合。本发明还涉及包含或编码分枝杆菌抗原和融合多肽的所述组合的核酸分子，载体，宿主细胞和组合物，以及重组产生它们的方法。本发明还涉及使用分枝杆菌抗原，融合多肽，载体，宿主细胞，特别是用于诱导或刺激针对分枝杆菌感染的免疫应答或由分枝杆菌感染引起或与分枝杆菌感染相关的任何疾病的组合的组合的方法。本发明还涉及针对可用于诊断分枝杆菌感染的这种分枝杆菌抗原和融合多肽的抗体以及检测方法以及包含分枝杆菌抗原，融合多肽，载体，宿主细胞的所述组合的试剂盒，组合物或抗体。

3. 发明授权

EP2872172B1 MYCOBACTERIAL ANTIGEN VACCINE 有权
公开(公告)号：EP2872172B1
公开(公告)日：2018-11-14
申请号：EP13735275.3
申请日：2013-07-10
申请人： Transgene SA
发明人： TUPIN, Emmanuel , MICOL, Romain , COUPET, Charles Antoine , INCHAUPSE, Geneviève , GOUANVIC, Marie , SILVESTRE, Nathalie , MARCHAND, Jean-Baptiste , BENY, Cécile
IPC分类号： A61K39/04
CPC分类号： A61K39/04 , A61K2039/51 , A61K2039/53 , C07K14/35 , C07K16/1289 , C07K2319/00 , C07K2319/40
摘要： The present invention relates generally to immunogenic combinations comprising at least five antigens of a Mycobacterium species as well as fusion thereof and nucleic acid molecules encoding such combined antigens and fusion. The present invention also relates to nucleic acid molecules, vectors, host cells and compositions comprising or encoding said combinations of mycobacterial antigens and fusion polypeptides as well as to methods for recombinantly producing them. The present invention also relates to methods of using said combinations of mycobacterial antigens, fusion polypeptides, vectors, host cells, compositions particularly for inducing or stimulating an immune response against a Mycobacterium infection or any disease caused by or associated with a Mycobacterium infection. The present invention also concerns antibodies directed to such mycobacterial antigens and fusion polypeptides that can be used in the diagnosis of a Mycobacterium infection and method of detection as well as kits of reagent comprising said combinations of mycobacterial antigens, fusion polypeptides, vectors, host cells, compositions or antibodies.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式