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1. 发明专利

JP2014103973A Corpuscular-ray beam irradiation apparatus and method for controlling the same 有权
标题翻译：微光束光束辐射装置及其控制方法
公开(公告)号：JP2014103973A
公开(公告)日：2014-06-09
申请号：JP2012256523
申请日：2012-11-22
申请人： Toshiba Corp , 株式会社東芝 , Natl Inst Of Radiological Sciences , 独立行政法人放射線医学総合研究所
发明人： HANAWA KATSUSHI , IZEKI YASUSHI , SUMIYA CHOICHI , FURUKAWA TAKUJI
IPC分类号： A61N5/10
摘要： PROBLEM TO BE SOLVED: To provide a corpuscular-ray beam irradiation apparatus that can be prevented from stopping beam irradiation due to erroneous information such as electric discharge.SOLUTION: The corpuscular-ray beam irradiation apparatus includes: a beam generation part for generating a corpuscular-ray beam; a beam scanning part for two-dimensionally scanning the generated corpuscular-ray beam according to a scan indication value; a sensor part which detects the scanning position of the corpuscular-ray beam, and in which first linear electrodes of a plurality of channels are placed in parallel in a first direction and second linear electrodes of a plurality of channels are placed in parallel in a second direction orthogonal to the first direction; a median processing part for calculating a median from the values of a plurality of signals output from the first and the second linear electrodes; a center of gravity position calculation part for calculating the position of the center of gravity of the corpuscular-ray beam from the calculated median of the plurality of signals; and a control part for stopping the emission of the corpuscular-ray beam when an error between the calculated center of gravity position and a preset reference scanning position is larger than a predetermined value.
摘要翻译：要解决的问题：提供一种能够防止由于诸如放电等错误信息而导致的光束照射的红细胞束射线照射装置。解决方案：粒子束射线束照射装置包括：用于产生红细胞的光束产生部分射线束用于根据扫描指示值二维地扫描生成的粒子束的光束扫描部分; 检测所述粒子束的扫描位置的传感器部分，并且其中多个通道中的第一线性电极沿第一方向平行放置，并且多个通道中的第二线性电极在第二方向上平行放置方向与第一方向正交; 中间处理部分，用于根据从第一和第二线性电极输出的多个信号的值计算中值; 重心位置计算部分，用于根据所计算的多个信号的中位数来计算粒子束射线束的重心位置; 以及当计算出的重心位置与预设基准扫描位置之间的误差大于预定值时停止发射红细胞束的控制部分。

2. 发明专利

JP2010060523A Beam position monitor and beam position measuring method of particle beam therapy device 有权
标题翻译：粒子束处理装置的光束位置监测器和光束位置测量方法
公开(公告)号：JP2010060523A
公开(公告)日：2010-03-18
申请号：JP2008228925
申请日：2008-09-05
申请人： Natl Inst Of Radiological Sciences , Toshiba Corp , 株式会社東芝 , 独立行政法人放射線医学総合研究所
发明人： FURUKAWA TAKUJI , INABA HIROSHI , SATO SHINJI , NODA KOJI , IZEKI YASUSHI , HANAWA KATSUSHI , AMEMORI KIYOYUKI , SUETAKE NORIO
IPC分类号： G01T1/29 , A61N5/10 , G21K5/04
摘要： PROBLEM TO BE SOLVED: To provide a beam position monitor and a beam position measuring method for a particle beam therapy device capable of measuring beam position of particle beam with sufficient precision even if it is in the raster scanning method and attains miniaturization or cost reduction of the beam position monitor. SOLUTION: A particle beam irradiated to a test substance 10 receives signal created in a condition where no scanning is implemented from one stopping irradiation spot to next stopping irradiation spot as a timing signal to create digital signal using collected charge acquired at a timing receiving the timing signal concerned. Thus created digital signal is used to calculate the beam position of the particle beam. The main configuration includes an I/V converter 501 creating voltage signal through I/V conversion of current output depending on collected charge, an ADC circuit 503 creating digital signal through A/D conversion of the created voltage signal, an FPGA 504 calculating the beam position using created digital signal, and a radiation dosage termination signal transmitting/receiving section 505 receiving timing signal. COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：解决的问题：提供一种用于粒子束治疗装置的束位置监测器和束位置测量方法，其能够以足够的精度测量粒子束的束位置，即使它是光栅扫描方法并且实现小型化，或者光束位置监视器的成本降低。照射到测试物质10的粒子束接收在从一个停止照射点到下一个停止照射点不进行扫描的条件下产生的信号作为定时信号，以使用在定时处采集的收集电荷来创建数字信号接收有关的定时信号。这样创建的数字信号用于计算粒子束的光束位置。主要配置包括：I / V转换器501，其根据收集的电荷产生电流输出的I / V转换产生电压信号; ADC电路503，通过所产生的电压信号的A / D转换产生数字信号;计算光束的FPGA504 使用创建的数字信号的位置，以及接收定时信号的辐射剂量终止信号发送/接收部分505。版权所有（C）2010，JPO＆INPIT

3. 发明专利

JP2011161056A Particle beam irradiator and control method for the same 有权
标题翻译：颗粒光束辐射体及其控制方法
公开(公告)号：JP2011161056A
公开(公告)日：2011-08-25
申请号：JP2010028047
申请日：2010-02-10
申请人： Natl Inst Of Radiological Sciences , Toshiba Corp , 株式会社東芝 , 独立行政法人放射線医学総合研究所
发明人： IZEKI YASUSHI , HANAWA KATSUSHI , MAEDA KAZUNAO , SUMIYA CHOICHI , FURUKAWA TAKUJI , INABA HIROSHI , SATO SHINJI , NODA KOJI
IPC分类号： A61N5/10 , G01T1/29 , G21K5/04
CPC分类号： A61N5/10 , A61N5/1043 , A61N5/1075 , A61N2005/1074 , A61N2005/1087 , G01T1/2935
摘要： PROBLEM TO BE SOLVED: To provide a particle beam irradiator for measuring and displaying dose two-dimensional distribution when scanning with a simple structure while suppressing degradation of a particle beam shape low. SOLUTION: The particle beam irradiator includes: a beam generation unit for generating particle beam; a beam emission control unit for controlling emission of the particle beam; a beam scanning unit for two-dimensionally scanning the particle beam; a sensor unit in which a plurality of first linear electrodes are placed in parallel in a first direction and a plurality of second linear electrodes are placed in parallel in a second direction orthogonal to the first direction; a beam shape calculation unit for calculating a center of gravity of the particle beam according to first signals outputted by the respective first linear electrodes and second signals outputted by the respective second linear electrodes to obtain a two-dimensional beam shape of the particle beam around the center of gravity; a storage unit for accumulating and storing the two-dimensional beam shape; and a display unit for displaying the two-dimensional beam shape as a two-dimensional distribution of the dose. COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：要解决的问题：提供一种粒子束照射器，用于在以简单的结构进行扫描时测量和显示剂量二维分布，同时抑制粒子束形状的降低。解决方案：粒子束照射器包括：用于产生粒子束的光束产生单元; 用于控制所述粒子束的发射的光束发射控制单元; 用于二维扫描粒子束的束扫描单元; 传感器单元，其中多个第一线性电极沿第一方向平行放置，并且多个第二线性电极在与第一方向正交的第二方向上平行放置; 光束形状计算单元，用于根据由各个第一线性电极输出的第一信号和由第二线性电极输出的第二信号来计算粒子束的重心，以获得粒子束的二维束形状重心; 用于累积和存储二维光束形状的存储单元; 以及显示单元，用于将二维束形状显示为剂量的二维分布。版权所有（C）2011，JPO＆INPIT

4. 发明专利

JP2014103974A Corpuscular-ray beam irradiation apparatus and method for controlling the same 审中-公开
标题翻译：微光束光束辐射装置及其控制方法
公开(公告)号：JP2014103974A
公开(公告)日：2014-06-09
申请号：JP2012256524
申请日：2012-11-22
申请人： Toshiba Corp , 株式会社東芝 , Natl Inst Of Radiological Sciences , 独立行政法人放射線医学総合研究所
发明人： HANAWA KATSUSHI , SUMIYA CHOICHI , FURUKAWA TAKUJI
IPC分类号： A61N5/10 , A61B6/00
摘要： PROBLEM TO BE SOLVED: To provide a corpuscular-ray beam irradiation apparatus that can irradiate an assumed irradiation position with beam, with high accuracy without stopping the irradiation of the beam even if a beam position has been moved during therapeutic irradiation.SOLUTION: The corpuscular-ray beam irradiation apparatus includes: a beam generation part; a beam scanning part for scanning a corpuscular-ray beam according to a scan indication value; a sensor part in which a plurality of a first linear electrodes are placed in parallel in a first direction and a plurality of second linear electrodes are placed in parallel in a second direction orthogonal to the first direction; a center of gravity position calculation part for calculating the position of the center of gravity of the corpuscular-ray beam from first signals output from the respective first linear electrodes and second signals output from the respective second linear electrodes; and a scan control part for obtaining an error between the calculated center of gravity position and a preset reference scan position, correcting the scan indication value by feedback control suppressing the error, and outputting the corrected scan indication value to the beam scanning part.
摘要翻译：要解决的问题：提供一种即使在治疗照射期间光束位置已经移动的情况下，也可以高精度地照射假定的照射位置的红细胞束射线照射装置，而不停止光束的照射。解决方案：红细胞射线束照射装置包括：光束产生部; 用于根据扫描指示值扫描红细胞束的束扫描部分; 其中多个第一线性电极沿第一方向平行放置的传感器部分和多个第二线性电极在与第一方向正交的第二方向上平行放置; 重心位置计算部分，用于根据从各个第一线性电极输出的第一信号和从各个第二线性电极输出的第二信号来计算粒子束的重心位置; 以及扫描控制部分，用于获得所计算的重心位置与预设参考扫描位置之间的误差，通过抑制误差的反馈控制校正扫描指示值，并将校正的扫描指示值输出到光束扫描部分。

5. 发明专利

JP2011161055A Corpuscular beam irradiation device and control method for the same 有权
标题翻译：共射束辐射装置及其控制方法
公开(公告)号：JP2011161055A
公开(公告)日：2011-08-25
申请号：JP2010028046
申请日：2010-02-10
申请人： Natl Inst Of Radiological Sciences , Toshiba Corp , 株式会社東芝 , 独立行政法人放射線医学総合研究所
发明人： HANAWA KATSUSHI , IZEKI YASUSHI , SUMIYA CHOICHI , FURUKAWA TAKUJI , INABA HIROSHI , SATO SHINJI , NODA KOJI
IPC分类号： A61N5/10 , G21K5/04
CPC分类号： A61N5/1043 , A61N5/1071 , A61N2005/1074 , A61N2005/1087 , G21K1/025
摘要： PROBLEM TO BE SOLVED: To provide a corpuscular beam irradiation device for measuring a dose each beam highly reliably and measuring a leaked dose due to instantaneous beam emission with high sensitivity. SOLUTION: The corpuscular beam irradiation device includes: an emission control unit for controlling emission of the corpuscular beam and stop of the emission; a control unit for sequentially changing irradiation positions of the corpuscular beam to an affected part; first and second dosimeters for measuring dose ratios of corpuscular beams radiated to the affected part; and an abnormality determination part for obtaining first and second intersection dose measurement values respectively by accumulating dose ratios outputted by the first and second dosimeters each prescribed determination period, and performing second abnormality determination that there is abnormality at least in either case that the first intersection dose measurement value is beyond a predetermined first criterion range or that the second intersection dose measurement value is beyond a predetermined second criterion range, and outputting an interlock signal for stopping emission of the particle beam. COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：要解决的问题：提供一种用于高度可靠地测量每个束的剂量并且以高灵敏度测量由于瞬时束发射引起的泄漏剂量的粒子束照射装置。解决方案：粒子束照射装置包括：发射控制单元，用于控制粒子束的发射并停止发射; 控制单元，用于将粒子束的照射位置顺序地改变到患部; 用于测量辐射到受影响部位的红细胞束的剂量比的第一和第二剂量计; 以及异常判定部，其分别通过累积由所述第一和第二剂量计在每个规定判定期间输出的剂量比率来获得第一和第二交叉点剂量测量值，并且进行至少在任一种情况下存在异常的第二异常判定，测量值超过预定的第一标准范围，或者第二交叉点剂量测量值超过预定的第二标准范围，并且输出用于停止发射粒子束的互锁信号。版权所有（C）2011，JPO＆INPIT

6. 发明专利

JP2010227464A Radiation exposure system 有权
标题翻译：辐射曝光系统
公开(公告)号：JP2010227464A
公开(公告)日：2010-10-14
申请号：JP2009080857
申请日：2009-03-30
申请人： Natl Inst Of Radiological Sciences , 独立行政法人放射線医学総合研究所
发明人： FURUKAWA TAKUJI , INABA HIROSHI , SATO SHINJI , SHIRAI TOSHIYUKI , NODA KOJI
IPC分类号： A61N5/10 , G21K5/00 , G21K5/04
摘要： PROBLEM TO BE SOLVED: To provide a radiation exposure system which can shorten the exposure time of radiation.
SOLUTION: An exposure position control part 44 has a radiation dose integration section 44a which integrates a radiation dose, an irradiation position change finalization signal acquisition section 44b which acquires an exposure position change finalization signal, a controlling delay determination section 44c, which determines as controlling delay when a radiation dose, which is integrated, reaches a radiation dose to be exposed in an exposure position and the exposure position change finalization signal is not acquired and determines that controlling delay is eliminated when the exposure position change finalization signal is acquired after that, and an exposure position change starting signal output part 44d which outputs an exposure position change start signal to an exposure position change device 31, when determined as controlling delay, the radiation dose integration section 44a integrates a radiation dose, in which monitoring is carried out, as a radiation dose in the following exposure position and the exposure position change starting signal output part 44d outputs an exposure position change start signal about the following exposure position when determined that controlling delay is eliminated.
COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：要解决的问题：提供可以缩短辐射的曝光时间的辐射曝光系统。
解决方案：曝光位置控制部分44具有放射剂量积分部分44a，放射剂量积分，获取曝光位置变化终止信号的照射位置变化结束信号获取部分44b，控制延迟确定部分44c，当被积分的辐射剂量达到要暴露于曝光位置的曝光剂量并且未获取曝光位置变化结束信号时确定为控制延迟，并且当获取曝光位置变化结束信号时确定控制延迟被消除之后，将曝光位置改变开始信号输出到曝光位置变更装置31的曝光位置变更开始信号输出部44d，当被确定为控制延迟时，放射线剂量积分部44a将放射剂量作为辐射剂量进行随访当确定控制延迟被消除时，曝光位置改变启动信号输出部分44d输出关于随后的曝光位置的曝光位置改变开始信号。版权所有（C）2011，JPO＆INPIT

7. 发明专利

JP2008071494A Charged particle beam accelerator, and particle beam irradiation system using the same 有权
标题翻译：充电颗粒光束加速器和使用其的颗粒光束辐照系统
公开(公告)号：JP2008071494A
公开(公告)日：2008-03-27
申请号：JP2006246308
申请日：2006-09-12
申请人： Mitsubishi Electric Corp , Natl Inst Of Radiological Sciences , 三菱電機株式会社 , 独立行政法人放射線医学総合研究所
发明人： NAKANISHI TETSUYA , NODA KOJI , FURUKAWA TAKUJI
IPC分类号： H05H13/04 , A61N5/10
摘要： PROBLEM TO BE SOLVED: To provide a charged particle beam accelerator capable of solving a problem where a stable region boundary of betatron vibration is changed and a charged particle beam is emitted depending on ripple of main electromagnet power; and to provide a particle beam irradiation system using the charged particle beam accelerator.
SOLUTION: Beam emission from an orbit is operated at emission timing of a means changing a stable region boundary, and a high-frequency signal generation part of an RFKO apparatus (high frequency generator) 8 is swept from a frequency f1 bringing a charged particle beam in the vicinity of the center of a revolving beam into a resonant state to a frequency f2 bringing the charged particle beam nearly at the maximum amplitude in the stable region boundary into a resonant state, and controlled by an amplitude modulation waveform of f1>f2.
COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：解决问题的方法：提供一种能够解决由于主电磁力的纹波而发生反应器振荡的稳定区域边界而发生带电粒子束的问题的带电粒子束加速器，并提供使用带电粒子束加速器的粒子束照射系统。解决方案：来自轨道的光束发射在改变稳定区域边界的装置的发射定时处操作，并且RFKO装置（高频发生器）8的高频信号产生部分从频率f1扫描，从而使带电粒子束在旋转光束的中心附近成为谐振状态，使频率f2使得在稳定区域边界中几乎达到最大振幅的带电粒子束成为谐振状态，并且由幅度调制波形f1 > F2。版权所有（C）2008，JPO＆INPIT

8. 发明专利

JP2012009181A Beam emission device and control method thereof 有权
标题翻译：射束发射装置及其控制方法
公开(公告)号：JP2012009181A
公开(公告)日：2012-01-12
申请号：JP2010142081
申请日：2010-06-22
申请人： Natl Inst Of Radiological Sciences , 独立行政法人放射線医学総合研究所
发明人： MIZUSHIMA KOTA , FURUKAWA TAKUJI , SHIRAI TOSHIYUKI , NODA KOJI
IPC分类号： H05H13/04 , A61N5/10 , H05H7/10
摘要： PROBLEM TO BE SOLVED: To provide a beam emission device and a control method thereof capable of simultaneously supplying emission beams to two or more transport lines from one synchrotron without beam loss and increasing a synchrotron use efficiency per unit time in accordance with a beam use request.SOLUTION: The beam emission device R according to the present invention comprise: a synchrotron 1 where a particle beam goes around with betatron oscillation; a high-frequency acceleration cavity 3 that is provided in the synchrotron 1 and accelerates or decelerates when the particle beam is applied to a longitudinal high-frequency electric field parallel to an advance direction of the particle beam; and a beam transport line 2 to which the particle beam connected to and emitted from the synchrotron 1 is transported. This beam emission device includes control means for controlling a phase of the longitudinal high-frequency electric field caused by the high-frequency acceleration cavity 3 so that the phase is shifted by 180 degrees to the particle beam that goes around in a predetermined stationary state in the synchrotron 1 and for polarizing a momentum and an emission angle of the particle beam emitted from the synchrotron 1.
摘要翻译：解决的问题：提供一种射束发射装置及其控制方法，其能够同时从一个同步加速器向两根或更多条输送线提供发射束，而不会造成光束损失，并根据一个单位时间增加同步加速器的使用效率光束使用请求。解决方案：根据本发明的射束发射装置R包括：同步加速器1，其中粒子束以贝塔振荡方式绕过; 设置在同步加速器1中的高频加速腔3，并且当将粒子束施加到与粒子束的前进方向平行的纵向高频电场时加速或减速; 以及与该同步加速器1连接并从同步加速器1发射的粒子束的波束输送线2。该光束发射装置包括用于控制由高频加速腔3引起的纵向高频电场的相位的控制装置，使得相位相对于在预定的静止状态中绕过的粒子束偏移180度同步加速器1并用于偏振从同步加速器1发射的粒子束的动量和发射角。版权所有（C）2012，JPO＆INPIT

9. 发明专利

JP2011233475A Beam control device, particle beam irradiation device and control method thereof 有权
标题翻译：光束控制装置，粒子束辐射装置及其控制方法
公开(公告)号：JP2011233475A
公开(公告)日：2011-11-17
申请号：JP2010105386
申请日：2010-04-30
申请人： Natl Inst Of Radiological Sciences , 独立行政法人放射線医学総合研究所
发明人： MIZUSHIMA KOTA , FURUKAWA TAKUJI , SHIRAI TOSHIYUKI , NODA KOJI
IPC分类号： H05H13/04 , A61N5/10
摘要： PROBLEM TO BE SOLVED: To provide an inexpensive beam control device by which fluctuations in dose are prevented, the dose of the preset amount is obtained, and to provide a particle beam irradiation device, and a control method thereof.SOLUTION: The beam control device 1 includes a synchrotron 2 and performs taking-out of particle beams using resonance of betatron vibration from the synchrotron 2. This device includes: a multipole electromagnet 6 corresponding to the degree of the resonance for separatrix formation by the particle beams in the synchrotron 2; and a beam control means in which beam spill ripple of the particle beam is reduced to the specified quantity or less by controlling the magnetic field strength of the multipole electromagnet 6 on a high level while keeping the formed separatrix area in a desired size.
摘要翻译：要解决的问题：为了提供一种廉价的光束控制装置，通过该光束控制装置防止剂量波动，获得预设量的剂量，并提供粒子束照射装置及其控制方法。解决方案：光束控制装置1包括同步加速器2，并使用来自同步加速器2的贝塔振子的共振来取出粒子束。该装置包括：多极电磁体6，其对应于用于分离矩阵形成的共振度通过同步加速器2中的粒子束; 以及光束控制装置，其中通过在保持所形成的分割面积保持期望尺寸的同时将多极电磁体6的磁场强度控制在高水平，将粒子束的束溢出波动减小到规定量以下。版权所有（C）2012，JPO＆INPIT

10. 发明专利

JP2010220975A Particle ray irradiation apparatus 有权
标题翻译：颗粒射线辐射装置
公开(公告)号：JP2010220975A
公开(公告)日：2010-10-07
申请号：JP2009074731
申请日：2009-03-25
申请人： Natl Inst Of Radiological Sciences , 独立行政法人放射線医学総合研究所
发明人： FURUKAWA TAKUJI , INABA HIROSHI , SATO SHINJI , SHIRAI TOSHIYUKI , NODA KOJI
IPC分类号： A61N5/10 , G21K5/00 , G21K5/04
摘要： PROBLEM TO BE SOLVED: To provide a particle ray irradiation apparatus which prevents a radiation dose-deficient region from being generated to allow formation of a precise distribution of radiation dose.
SOLUTION: The particle ray irradiation apparatus, which irradiates an irradiated object P1 with particle ray b1 sent from an accelerator 6, includes an irradiation dose monitor 3, a primary counter C1, and a secondary counter C2, wherein the irradiation dose monitor 3 determines the exposure dose of the particle ray b1 with which the irradiated object P1 is irradiated; the primary counter C1 bases on the signals of the exposure doses transmitted from the irradiation dose monitor 3 to integrate the doses of particle ray b1 to which the object P1 is exposed when the apparatus is set to irradiate the object P1 with particle ray b1; and the secondary counter C2 bases on the signals of the exposure doses to integrate the leaked doses of particle ray b1 to which the object P1 is unintentionally exposed when the apparatus is set to exempt the object P1 from being irradiated with particle ray b1.
COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：要解决的问题：提供一种防止辐射剂量缺陷区域产生以允许形成辐射剂量的精确分布的粒子射线照射装置。解决方案：从加速器6发送的粒子射线b1照射被照射物体P1的粒子射线照射装置包括照射剂量监视器3，初级计数器C1和次级计数器C2，其中照射剂量监视器 3确定照射物体P1照射的粒子射线b1的曝光量; 主计数器C1基于从照射剂量监视器3发送的暴露剂量的信号，以将当设备被设置成用粒子射线b1照射物体P1时将对象P1暴露于的粒子束b1的剂量进行积分; 并且次级计数器C2基于曝光剂量的信号，以将当设备被设定为豁免对象P1被粒子射线b1照射时，对象物P1被无意地暴露的粒子射线b1的泄漏剂量进行积分。版权所有（C）2011，JPO＆INPIT

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