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1. 发明授权

US06150355A Phenylpiperidine derivative 失效
标题翻译：苯基哌啶衍生物
公开(公告)号：US06150355A
公开(公告)日：2000-11-21
申请号：US43154
申请日：1998-03-13
申请人： Toshiaki Kumazawa , Hirokazu Koshimura , Shigeru Aono , Shunji Ichikawa , Shigeto Kitamura
发明人： Toshiaki Kumazawa , Hirokazu Koshimura , Shigeru Aono , Shunji Ichikawa , Shigeto Kitamura
IPC分类号： C07D211/52 , C07D401/04 , C07D405/04 , C07D491/04 , C07D491/044 , C07D211/06 , A01N43/42 , A01N43/46 , C07D221/06 , C07D498/00
CPC分类号： C07D401/04 , C07D211/52 , C07D405/04 , C07D491/04
摘要： A phenylpiperidine derivative or pharmaceutical acceptable salt thereof represented by formula (I): ##STR1## wherein X represents CH or N; Y--Z represents CH.sub.2 --O, CH.sub.2 --S, CH.sub.2 --CH.sub.2, CH.dbd.CH or CONR.sup.5 (wherein R.sup.5 represents hydrogen or lower alkyl); R.sup.1 represents hydrogen, lower alkyl, halogen, lower alkoxy or trifluoromethyl; and R.sup.2, R.sup.3 and R.sup.4 are the same or different and each represents hydrogen, lower alkyl or QR.sup.6 (wherein Q represents a single bond or lower alkylene, and R.sup.6 represents hydroxy, lower alkoxyalkoxy, lower alkoxy, lower alkylthio, nitro, halogen, lower alkanoyloxy, lower alkoxycarbonyl, lower alkanoyl or carboxyl).The present invention provides novel phenylpiperidine derivatives useful as analgesics.
摘要翻译： PCT No.PCT / JP96 / 02589 Sec。 371日期1998年3月13日 102（e）1998年3月13日PCT PCT 1996年9月11日PCT公布。公开号WO97 / 10213 日期：1997年3月20日由式（I）表示的苯基哌啶衍生物或其药学上可接受的盐：其中X表示CH或N; Y-Z表示CH 2 -O，CH 2 -S，CH 2 -CH 2，CH = CH或CONR 5（其中R 5表示氢或低级烷基）。 R 1表示氢，低级烷基，卤素，低级烷氧基或三氟甲基; 并且R 2，R 3和R 4相同或不同，各自表示氢，低级烷基或QR6（其中Q表示单键或低级亚烷基，R6表示羟基，低级烷氧基烷氧基，低级烷氧基，低级烷硫基，硝基，卤素，低级烷酰氧基，低级烷氧基羰基，低级烷酰基或羧基）。本发明提供了用作止痛剂的新型苯基哌啶衍生物。

2. 发明授权

US5543415A Antidepressants 失效
标题翻译：抗抑郁药
公开(公告)号：US5543415A
公开(公告)日：1996-08-06
申请号：US199142
申请日：1994-02-25
申请人： Fumio Suzuki , Junichi Shimada , Akio Ishii , Joji Nakamura , Shunji Ichikawa , Shigeto Kitamura , Nobuaki Koike
发明人： Fumio Suzuki , Junichi Shimada , Akio Ishii , Joji Nakamura , Shunji Ichikawa , Shigeto Kitamura , Nobuaki Koike
IPC分类号： F16B37/04 , A61K31/00 , A61K31/52 , B29C65/08 , B29C65/72 , C07D473/06 , C07D473/08 , C07D473/12 , C07D473/20 , C07D473/22 , A61K31/505
CPC分类号： A61K31/52 , C07D473/06 , C07D473/08 , F16B37/048
摘要： The present invention relates to an antidepressant containing as an active ingredient a xanthine derivative or a pharmaceutically acceptable salt thereof, the xanthine derivative being represented by Formula (I) : ##STR1## in which R.sup.1, R.sup.2, and R.sup.3 represent independently hydrogen, lower alkyl, lower alkenyl;R.sup.4 represents cycloalkyl, --(CH.sub.2).sub.n --R.sup.5 (in which R.sup.5 represents substituted or unsubstituted aryl or a substituted or unsubstituted heterocyclic group; and n is an integer of 0 to 4), or ##STR2## (in which Y.sup.1 and Y.sup.2 represent independently hydrogen, halogen or lower alkyl; and Z represents substituted or unsubstituted aryl, ##STR3## (in which R.sup.6 represents hydrogen, hydroxy, lower alkyl, lower alkoxy, halogen, nitro, or amino; and m represents an integer of 1 to 3), or a substituted or unsubstituted heterocyclic group);and X.sup.1 and X.sup.2 represent independently O or S.
摘要翻译： PCT No.PCT / JP93 / 00931 Sec。 371日期1994年2月25日 102（e）1994年2月25日PCT PCT 1993年7月7日PCT公布。第WO94 / 01114号公报日本时间1994年1月20日本发明涉及含有作为活性成分的黄嘌呤衍生物或其药学上可接受的盐的抗抑郁药，黄嘌呤衍生物由式（I）表示：其中R1，R2，并且R 3独立地表示氢，低级烷基，低级烯基; R 4表示环烷基， - （CH 2）n -R 5（其中R 5表示取代或未取代的芳基或取代或未取代的杂环基; n为0〜4的整数）或

3. 发明授权

US5703085A Xanthine derivatives 失效
标题翻译：黄嘌呤衍生物
公开(公告)号：US5703085A
公开(公告)日：1997-12-30
申请号：US537770
申请日：1995-10-20
申请人： Fumio Suzuki , Nobuaki Koike , Junichi Shimada , Joji Nakamura , Shizuo Shiozaki , Shigeto Kitamura , Shunji Ichikawa , Hiroshi Kase , Hiromi Nonaka
发明人： Fumio Suzuki , Nobuaki Koike , Junichi Shimada , Joji Nakamura , Shizuo Shiozaki , Shigeto Kitamura , Shunji Ichikawa , Hiroshi Kase , Hiromi Nonaka
IPC分类号： C07D473/06 , A61K31/52 , C07D473/10 , C07D473/12
CPC分类号： C07D473/06
摘要： The present invention relates to novel xanthine derivatives and pharmaceutically acceptable salts thereof, represented by Formula (I): ##STR1## wherein R.sup.1, R.sup.2, and R.sup.3 independently represent hydrogen, lower alkyl, lower alkenyl, or lower alkynyl, R.sup.4 represents lower alkyl, or substituted or unsubstituted aryl, R.sup.5 and R.sup.6 independently represent hydrogen, lower alkyl, and lower alkoxy, or R.sup.5 and R.sup.6 are combined together to represent --O--(CH.sub.2)p--O-- (p is an integer of 1 to 3), n represents 0, 1, or 2, and m represents 1 or 2. The compounds of the present invention have an adenosine A.sub.2 receptor antagonistic activity, and are useful for the treatment or prevention of various kinds of diseases caused by hyperergasia of adenosine A.sub.2 receptors (for example, Parkinson's disease, senile dementia, depression, asthma, and osteoporosis).
摘要翻译： PCT No.PCT / JP95 / 00267 Sec。 371 1995年10月20日第 102（e）1995年10月20日日期PCT提交1995年2月23日PCT公布。公开号WO95 / 23148 日期：1995年8月31日本发明涉及由式（I）表示的新颖的黄嘌呤衍生物及其药学上可接受的盐：其中R1，R2和R3独立地表示氢，低级烷基，低级链烯基或低级炔基，R 4表示低级烷基或取代或未取代的芳基，R 5和R 6独立地表示氢，低级烷基和低级烷氧基，或者R 5和R 6结合在一起代表-O-（CH 2）p O-（p是整数 1〜3），n表示0,1或2，m表示1或2.本发明化合物具有腺苷A2受体拮抗活性，可用于治疗或预防各种疾病腺苷A2受体（例如帕金森病，老年性痴呆，抑郁症，哮喘和骨质疏松症）的过度高血症。

4. 发明授权

US5565460A Therapeutic purine agents for parkinson's disease 失效
标题翻译：治疗帕金森病的嘌呤药物
公开(公告)号：US5565460A
公开(公告)日：1996-10-15
申请号：US367346
申请日：1995-03-03
申请人： Fumio Suzuki , Junichi Shimada , Nobuaki Koike , Shunji Ichikawa , Joji Nakamura , Tomoyuki Kanda , Shigeto Kitamura
发明人： Fumio Suzuki , Junichi Shimada , Nobuaki Koike , Shunji Ichikawa , Joji Nakamura , Tomoyuki Kanda , Shigeto Kitamura
IPC分类号： A61K31/505 , A61K31/53 , C07D487/04 , A61K31/535 , A61K31/54
CPC分类号： C07D487/04 , A61K31/505 , A61K31/53
摘要： The present invention relates to a therapeutic agent for Parkinson's disease containing as an active ingredient a polycyclic compound or a pharmaceutically acceptable salt thereof, the compound being represented by the following Formula (I): ##STR1## and A represents N or CR.sup.5 (in which R.sup.5 represents hydrogen, or substituted or unsubstituted lower alkyl), or represented by the following Formula (II): ##STR2## wherein Y, R.sup.6 and R.sup.8 are as defined herein and B and the adjacent two carbon atoms are combined to form a substituted or unsubstituted, partially saturated or unsaturated, monocyclic or bicyclic, carbocyclic or heterocyclic group.
摘要翻译： PCT No.PCT / JP94 / 01196 Sec。 371日期1995年3月3日 102（e）1995年3月3日PCT PCT 1994年7月20日PCT公布。公开号WO95 / 03806 日期：1995年2月9日本发明涉及含有作为活性成分的多环化合物或其药学上可接受的盐的帕金森病治疗剂，该化合物由下式（I）表示：＆lt; IMAGE＆gt;（I）和 A表示N或CR 5（其中R 5表示氢或取代或未取代的低级烷基），或由下式（II）表示：其中Y，R 6和R 8如本文所定义，B和相邻的两个碳原子结合形成取代或未取代的，部分饱和或不饱和的单环或双环，碳环或杂环基团。

5. 发明授权

US5789407A Method of treating depression with certain triazine derivatives 失效
标题翻译：用某些三嗪衍生物治疗抑郁症的方法
公开(公告)号：US5789407A
公开(公告)日：1998-08-04
申请号：US424397
申请日：1995-04-25
申请人： Fumio Suzuki , Nobuaki Koike , Junichi Shimada , Shigeto Kitamura , Shunji Ichikawa , Joji Nakamura , Shizuo Shiozaki
发明人： Fumio Suzuki , Nobuaki Koike , Junichi Shimada , Shigeto Kitamura , Shunji Ichikawa , Joji Nakamura , Shizuo Shiozaki
IPC分类号： A61K31/53 , C07D487/04 , A61K31/535
CPC分类号： C07D487/04 , A61K31/53
摘要： The present invention relates to an antidepressant containing as an active ingredient a triazine derivative or a pharmaceutically acceptable salt thereof, the derivative being represented by the following Formula (I): ##STR1## in which, R.sup.1 represents hydrogen, substituted or unsubstituted lower alkyl, or substituted or unsubstituted lower alkanoyl; R.sup.2 represents hydrogen, substituted or unsubstituted lower alkyl, substituted or unsubstituted lower alkenyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted aryl, substituted or unsubstituted aralkyl, or a substituted or unsubstituted heterocyclic group; R.sup.3 represents a substituted or unsubstituted heterocyclic group; X represents a single bond, O, S, S(O), S(O).sub.2, or NR.sup.4 (in which R.sup.4 represents hydrogen, or substituted or unsubstituted lower alkyl; or R.sup.2 and NR.sup.4 are combined to form a substituted or unsubstituted 4 to 6-membered saturated heterocyclic group); and A represents N or CR.sup.5 (in which R.sup.5 represents hydrogen, or substituted or unsubstituted lower alkyl).
摘要翻译： PCT No.PCT / JP94 / 01455 Sec。 371日期1995年04月25日 102（e）日期1995年4月25日PCT 1994年9月2日PCT公布。公开号WO95 / 07282 日期：1995年3月16日本发明涉及含有作为活性成分的三嗪衍生物或其药学上可接受的盐的抗抑郁药，该衍生物由下式（I）表示：其中，R 1表示氢，取代或未取代的低级烷基或取代或未取代的低级烷酰基; R 2表示氢，取代或未取代的低级烷基，取代或未取代的低级烯基，取代或未取代的环烷基，取代或未取代的芳基，取代或未取代的芳烷基或取代或未取代的杂环基; R3表示取代或未取代的杂环基; X表示单键，O，S，S（O），S（O）2或NR4（其中R4表示氢或取代或未取代的低级烷基;或R2和NR4组合形成取代或未取代的4 至6元饱和杂环基）; A表示N或CR5（其中R5表示氢或取代或未取代的低级烷基）。

6. 发明授权

US07938005B2 Acceleration sensor chip package 有权
标题翻译：加速度传感器芯片封装
公开(公告)号：US07938005B2
公开(公告)日：2011-05-10
申请号：US12607407
申请日：2009-10-28
申请人： Shunji Ichikawa
发明人： Shunji Ichikawa
IPC分类号： G01P15/08
CPC分类号： G01P1/023 , G01P15/123 , H01L2224/48091 , H01L2224/48465 , H01L2224/49175 , H01L2224/73265 , H01L2924/10253 , H01L2924/1461 , H01L2924/00014 , H01L2924/00
摘要： An acceleration sensor chip package includes an acceleration sensor chip; a sensor control chip; a re-wiring layer; an outer terminal; a sealing portion; and a substrate. The acceleration sensor chip includes a frame portion; a movable structure; a detection element; and an electrode pad electrically. The re-wiring layer has a wiring portion connected to the electrode pad. The electrode pad is electrically connected to a conductive bump. The sensor control chip has a sensor control electrode pad electrically connected to the conductive bump. The outer terminal is connected to the wiring portion and disposed in the outer region. The sealing portion seals the sensor control chip, the electrode pad, and the re-wiring layer, so that the movable structure is movable. The substrate is attached to the acceleration sensor chip to seal an opening portion.
摘要翻译：加速度传感器芯片封装包括加速度传感器芯片; 传感器控制芯片; 重新布线层; 外部终端; 密封部分; 和基材。加速度传感器芯片包括框架部分; 可移动结构; 检测元件; 和电极垫。再布线层具有连接到电极焊盘的布线部分。电极焊盘电连接到导电凸块。传感器控制芯片具有电连接到导电凸块的传感器控制电极焊盘。外部端子连接到布线部分并且设置在外部区域中。密封部密封传感器控制芯片，电极焊盘和再布线层，使得可移动结构是可移动的。衬底附接到加速度传感器芯片以密封开口部分。

7. 发明授权

US4962107A Agent for cerebral protection 失效
标题翻译：脑保护剂
公开(公告)号：US4962107A
公开(公告)日：1990-10-09
申请号：US321692
申请日：1989-03-10
申请人： Joji Nakamura , Kazuhiro Kubo , Shunji Ichikawa , Hajime Takahashi , Keisuke Isozumi , Toyofumi Yamada
发明人： Joji Nakamura , Kazuhiro Kubo , Shunji Ichikawa , Hajime Takahashi , Keisuke Isozumi , Toyofumi Yamada
IPC分类号： A61K31/445 , A61K31/495 , A61K31/535 , A61K31/5375 , A61K31/54 , A61P25/28 , C07D211/16 , C07D211/22 , C07D211/46 , C07D265/30 , C07D265/32 , C07D279/12 , C07D295/18 , C07D295/185
CPC分类号： C07D265/30 , C07D211/16 , C07D211/22 , C07D279/12 , C07D295/185
摘要： Compounds of the general formula ##STR1## wherein: X is halogen or trifluoromethyl;R.sub.1 is hydrogen, halogen or trifluoromethyl;R.sub.2 is hydrogen methyl or hydroxymethyl;R.sub.3 is hydrogen or lower alkyl; andY is methylene, methylene substituted with a lower alkyl or hydroxyl group, sulfinyl, sulfonyl, oxygen or sulfur, exhibit a cerebral protective effect and are applicable to the treatment of cerebral ischaemia and cerebral hypoxia.The compounds may be made by acylating a suitable piperidine or morpholine with the appropriate cinnamoyl chloride, and if necessary oxidizing the reaction product.

8. 发明授权

US09084961B2 Gas-liquid contacting plate, gas-liquid contacting laminated block body, gas-liquid contacting laminated structure and gas purification device 有权
标题翻译：气液接触板，气液接触层叠块体，气液接触叠层结构和气体净化装置
公开(公告)号：US09084961B2
公开(公告)日：2015-07-21
申请号：US13813359
申请日：2011-12-08
申请人： Tatsuya Tsujiuchi , Hiromitsu Nagayasu , Hiroshi Tanaka , Takuya Hirata , Keiji Fujikawa , Ryuji Yoshiyama , Yuichiro Sato , Toyoshi Nakagawa , Tsuyoshi Oishi , Motomichi Ochiai , Kei Shioya , Shunji Ichikawa , Akihiro Kojima
发明人： Tatsuya Tsujiuchi , Hiromitsu Nagayasu , Hiroshi Tanaka , Takuya Hirata , Keiji Fujikawa , Ryuji Yoshiyama , Yuichiro Sato , Toyoshi Nakagawa , Tsuyoshi Oishi , Motomichi Ochiai , Kei Shioya , Shunji Ichikawa , Akihiro Kojima
IPC分类号： B01D53/18 , B01F3/04 , B01D53/14 , B01J19/32 , B01D3/28
CPC分类号： B01D53/18 , B01D3/28 , B01D53/1406 , B01D53/185 , B01D2257/204 , B01D2257/406 , B01D2257/504 , B01F3/04078 , B01J19/32 , B01J2219/32206 , B01J2219/32227 , B01J2219/32241 , B01J2219/32244 , B01J2219/32251 , B01J2219/32258 , B01J2219/32262 , B01J2219/32272 , B01J2219/32483 , B01J2219/3325
摘要： A gas-liquid contacting plate of the present invention in which a treatment liquid flows from an upper side to a lower side direction of a substrate and a part of gas being in contact with the treatment liquid is absorbed into the treatment liquid, includes a downward protruding saw teeth-shaped portion in which a lower end side of the substrate has pitches at predetermined gaps. Further, a pore group for liquid dispersion having a predetermined gap is provided in a plurality of lines, in the substrate. An arrangement thereof is a zigzag arrangement.
摘要翻译：本发明的气液接触板，其中处理液体从基板的上侧向下侧流动，并且与处理液接触的一部分气体被吸收到处理液中，包括向下突出的锯齿形部分，其中衬底的下端侧具有预定间隙的间距。此外，在基板中以多条线设置具有预定间隙的分散液孔组。其布置是锯齿形布置。

9. 发明申请

US20100152162A1 THERAPEUTIC AND/OR PREVENTIVE AGENTS FOR A SLEEP DISORDER 有权
标题翻译：治疗性疾病和/或预防性药物治疗睡眠障碍
公开(公告)号：US20100152162A1
公开(公告)日：2010-06-17
申请号：US11997585
申请日：2006-08-02
申请人： Noriaki Uesaka , Shunji Ichikawa , Takao Nakajima
发明人： Noriaki Uesaka , Shunji Ichikawa , Takao Nakajima
IPC分类号： A61K31/444 , A61K31/497 , A61K31/5377 , A61K31/541 , A61K31/427 , A61K31/553 , A61P25/00
CPC分类号： C07D417/14 , A61K31/4439 , A61K31/444 , A61K31/506 , A61K31/5377
摘要： It is intended to provide an agent for treating and/or preventing sleep disorder containing as an active ingredient a thiazole derivative represented by the general formula (I) (in the formula, R1 represents a five-membered aromatic heterocyclic group containing at least one oxygen atom or the like, R2 represents halogen or the like, and R3 represents —NR10R11 (in the formula, R10 and R11 are the same or different and represent a hydrogen atom or the like) or the like) or a pharmacologically acceptable salt thereof.
摘要翻译：旨在提供一种治疗和/或预防睡眠障碍的药剂，其含有作为活性成分的由通式（I）表示的噻唑衍生物（式中，R1表示含有至少一个氧的五元芳族杂环基）原子等，R2表示卤素等，R3表示-NR10R11（式中，R10和R11相同或不同，表示氢原子等）或其药理学上可接受的盐。

10. 发明申请

US20060236534A1 Method for manufacturing printed wiring board 审中-公开
标题翻译：印刷电路板制造方法
公开(公告)号：US20060236534A1
公开(公告)日：2006-10-26
申请号：US11406298
申请日：2006-04-19
申请人： Shunji Ichikawa
发明人： Shunji Ichikawa
IPC分类号： H05K3/36
CPC分类号： H05K3/403 , H05K3/0052 , H05K3/0094 , H05K3/064 , H05K3/243 , H05K3/28 , H05K3/4046 , H05K3/427 , H05K2201/09181 , H05K2201/0959 , H05K2201/10386 , H05K2203/0574 , H05K2203/1394 , Y10T29/49126 , Y10T29/49128 , Y10T29/49155 , Y10T29/49165
摘要： A method for manufacturing a printed wiring board comprises the steps of defining contact holes for forming both via holes forming through holes and contact terminals, in an insulated board with conductor layers formed over obverse and reverse surfaces thereof; forming conductive layers in inner peripheral surfaces of the via holes and the contact holes; forming etching masks for covering regions for forming wiring patterns and the through holes, over the obverse and reverse conductor layers, and etching the insulated board to remove the exposed conductor layers and the conductive layers formed over the inner peripheral surfaces of the exposed contact holes; and forming contact terminals for electrically connecting the obverse and reverse wiring patterns in the inner peripheral surfaces of the contact holes respectively.
摘要翻译：一种制造印刷电路板的方法包括以下步骤：在绝缘板上形成用于形成通孔和接触端子的通孔，用于形成在其正面和反面上形成有导体层的绝缘板; 在所述通孔和所述接触孔的内周面中形成导电层; 在正面和反面导体层上形成用于形成布线图案和通孔的覆盖区域的蚀刻掩模，并蚀刻绝缘板以去除暴露的导体层和形成在暴露的接触孔的内周表面上的导电层; 以及形成用于将接触孔的内周面中的正面和反向布线图案电连接的接触端子。

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