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1. 发明申请

US20070036734A1 Therapeutic agent for periodontal disease 审中-公开
标题翻译：牙周病治疗剂
公开(公告)号：US20070036734A1
公开(公告)日：2007-02-15
申请号：US10549289
申请日：2004-03-17
申请人： Tomoyuki Tahara , Yoshimitsu Abiko , Hiromasa Yoshie , Tetsuo Kobayashi , Toshio Umemoto , Nobushiro Hamada
发明人： Tomoyuki Tahara , Yoshimitsu Abiko , Hiromasa Yoshie , Tetsuo Kobayashi , Toshio Umemoto , Nobushiro Hamada
IPC分类号： A61K39/40 , C07K16/12 , A61K8/96 , G01N33/554 , C12N5/06
CPC分类号： C07K16/1257 , A61K2039/505 , C07K16/1203 , C07K2317/77
摘要： The present invention provides a human monoclonal antibody that has both activity of inhibiting the aggregation of pathogenic bacteria involved in periodontal diseases and activity of promoting sterilization by leukocytes, that is preferably a monoclonal antibody against 40-kDa OMP, which inhibits the binding of hemin, and that causes no concerns such as side effects. The present invention further provides an agent that acts against periodontal diseases containing the monoclonal antibody. The present invention relates to an antibody binding to 40-kDa OMP or a functional fragment thereof having at least one of (1) activity of inhibiting the coaggregation of P. gingivalis, (2) activity of promoting human neutrophilic phagocytosis, and (3) activity of inhibiting the binding of hemin to 40-kDa OMP.
摘要翻译：本发明提供一种具有抑制牙周疾病病原菌聚集的活性和促进白细胞灭活的活性的人单克隆抗体，其优选为40kDa OMP的单克隆抗体，其抑制血红素的结合，并且不会引起副作用等问题。本发明还提供了一种对含有单克隆抗体的牙周病作用的药剂。本发明涉及结合40-kDa OMP的抗体或其功能片段，其具有以下至少一种：（1）抑制牙龈卟啉单胞菌共聚的活性，（2）促进人嗜中性粒细胞吞噬作用的活性，和（3）抑制血红素与40-kDa OMP结合的活性。

2. 发明授权

US5224059A Device for measuring altitude and barometric pressure 失效
标题翻译：用于测量高度和大气压力的装置
公开(公告)号：US5224059A
公开(公告)日：1993-06-29
申请号：US794848
申请日：1991-11-21
申请人： Tatsuo Nitta , Toshio Umemoto , Hiroyuki Kihara
发明人： Tatsuo Nitta , Toshio Umemoto , Hiroyuki Kihara
IPC分类号： G01C5/06 , G04B47/06 , G04G21/02
CPC分类号： G04G21/02 , G01C5/06 , G04B47/06
摘要： A device for measuring altitude and barometric pressure having a barometric pressure sensor, an amplifying circuit for amplifying the output signal from the pressure sensor, an analog to digital converter for converting the output signal from the amplifying circuit to a digital signal, and an altitude information generator for generating altitude information from the output signal of the analog to digital converter. A display displays the altitude information from the altitude information generator and the pressure information detected by the pressure sensor with pressure variation information and converts it into precise altitude information in accordance with temperature compensation data and altitude compensating data based upon regional and time information. The device may be used in climbing or the like with remarkable reliability.
摘要翻译：一种用于测量具有大气压力传感器的高度和大气压力的装置，用于放大来自压力传感器的输出信号的放大电路，用于将来自放大电路的输出信号转换为数字信号的模数转换器，以及高度信息发生器，用于从模数转换器的输出信号产生高度信息。显示器显示来自高度信息发生器的高度信息和由压力变化信息由压力传感器检测到的压力信息，并根据区域和时间信息根据温度补偿数据和高度补偿数据将其转换成精确的高度信息。该装置可以用于具有显着可靠性的爬坡等。

3. 发明授权

US5331608A Electronic watch with an antenna for a receiving device 失效
标题翻译：带有接收设备天线的电子手表
公开(公告)号：US5331608A
公开(公告)日：1994-07-19
申请号：US36849
申请日：1993-03-25
申请人： Toshio Umemoto , Toshio Hiruta , Kunikazu Mochida
发明人： Toshio Umemoto , Toshio Hiruta , Kunikazu Mochida
IPC分类号： G04G21/04 , H01Q1/27 , G04C11/02
CPC分类号： G04G21/04 , G04R60/06 , G04R60/10 , H01Q1/273
摘要： In a wrist watch equipped with a receiving device, an antenna 19 having an antenna winding 19b, wound around an antenna core 19a with the end thereof being fixed, and having a conductible antenna terminal sheet 19d secured to an antenna winding frame 19c is inserted from a notch 10k in a dial 10 and secured with a screw 35 to an antenna support plate 33 which is secured to a circuit substrate 22, there by conducting the antenna 19 and the watch module. The construction ensures simplification of the watch module structure and easy conduction and securing of the antenna and the watch module and secured, with little influence on the receiving performance.
摘要翻译：在配备有接收装置的手表中，具有天线绕组19b的天线19从固定在天线绕组框架19c上的具有导电性的天线端子片19d被卷绕在固定在天线芯19a上的天线芯19a上，表盘10上的凹口10k，并通过螺钉35固定到固定到电路基板22的天线支撑板33，在那里通过导电天线19和手表模块。该结构确保了手表模块结构的简化，并且易于导通和固定天线和手表模块并且固定，对接收性能几乎没有影响。

4. 发明授权

US4783772A Wristwatch with pressure sensor 失效
标题翻译：手表带压力传感器
公开(公告)号：US4783772A
公开(公告)日：1988-11-08
申请号：US165361
申请日：1988-02-29
申请人： Toshio Umemoto , Toshio Hiruta , Hideo Uehara , Masato Yamada , Kunikazu Mochida
发明人： Toshio Umemoto , Toshio Hiruta , Hideo Uehara , Masato Yamada , Kunikazu Mochida
IPC分类号： B63C11/02 , G01C5/06 , G01C13/00 , G04B47/06 , G04G21/02 , G01L9/00
CPC分类号： G04G21/02 , B63C11/02 , G01C5/06 , G04B47/06
摘要： An electronic diving wristwatch having a pressure sensing depth meter provided in a projection on a case of the watch without interferring with the existing crown, pushbuttons, etc. The depth meter has a piezoelectric type sensing element which produces electrical output in response to the water pressure. The output is converted to a water depth which is displayed in a digital display window of the watch.
摘要翻译：一种具有压力感测深度计的电子潜水手表，其设置在手表的壳体上的突起中，而不会干扰现有的表冠，按钮等。深度计具有压电型感测元件，其响应于水压产生电输出。输出被转换为显示在手表的数字显示窗口中的水深。

5. 发明授权

US5966344A Watch containing light transmitting metallic dial 失效
标题翻译：手表包含透光金属表盘
公开(公告)号：US5966344A
公开(公告)日：1999-10-12
申请号：US917519
申请日：1997-08-26
申请人： Toshio Umemoto , Masami Fukuda , Kenji Shimoda , Yasuo Kitajima , Isamu Kobayashi , Yoshio Katsuki , Yurie Udoh
发明人： Toshio Umemoto , Masami Fukuda , Kenji Shimoda , Yasuo Kitajima , Isamu Kobayashi , Yoshio Katsuki , Yurie Udoh
IPC分类号： G04B19/12 , G04B19/14 , G04B19/30 , G04B19/06
CPC分类号： G04B19/30 , G04B19/12 , G04B19/14
摘要： A light transmitting metallic dial 50 is disposed above a cell 2 such as an EL device, a solar battery, or the like and the light transmitting type metallic dial 50 is secured by engaging an aligning portion 50b formed on the light transmitting type metallic dial 50 with an aligning portion 4b formed on a casing frame 4. In the light transmitting type metallic dial 50, light transmitting holes 50a and 51 constituting various characters, numerals, patterns, and the like are formed. Further, when the transparent plate is laminated on the light transmitting metallic dial 50, a clearance 7 is formed between the cell 2 and the transparent plate 5 using a spacer or the like.
摘要翻译：透光金属盘50设置在诸如EL器件，太阳能电池等的电池2之上，并且透光型金属拨盘50通过接合形成在透光型金属拨盘50上的对准部分50b而被固定具有形成在壳体框架4上的对准部4b。在透光型金属盘50中，形成构成各种字符，数字，图案等的透光孔50a和51。此外，当透光板层压在透光金属表盘50上时，使用间隔件等在电池单元2和透明板5之间形成间隙7。

6. 发明授权

US4251604A Battery assembly for electronic timepieces 失效
标题翻译：电子钟表电池组件
公开(公告)号：US4251604A
公开(公告)日：1981-02-17
申请号：US34501
申请日：1979-04-30
申请人： Toshio Umemoto
发明人： Toshio Umemoto
IPC分类号： G04C10/00 , H01M2/10
CPC分类号： H01M2/1044 , G04C10/00
摘要： A battery assembly for electronic timepieces includes a frame and an electric battery supported in and securely fitted to the frame. The frame has a portion which acts to produce an engagement with a substrate of the timepiece to keep the battery in position.
摘要翻译：一种用于电子钟表的电池组件包括框架和支撑在框架中并牢固地装配到框架上的电池。框架具有用于产生与钟表的基板的接合的部分，以将电池保持在适当位置。

7. 发明授权

US4232512A Solid state watch module construction 失效
标题翻译：固态手表模块结构
公开(公告)号：US4232512A
公开(公告)日：1980-11-11
申请号：US863536
申请日：1977-12-22
申请人： Kenichi Yoshikawa , Makoto Koshikawa , Toshio Umemoto , Tetsuo Satoh , Singo Ichikawa , Yoshiaki Kato
发明人： Kenichi Yoshikawa , Makoto Koshikawa , Toshio Umemoto , Tetsuo Satoh , Singo Ichikawa , Yoshiaki Kato
IPC分类号： G04G17/02 , H05K1/00 , H05K1/18 , G04C3/00 , G04B19/30 , G04B37/00
CPC分类号： G04G17/02 , H05K1/0284 , H05K1/182
摘要： A solid state watch module construction including a plastic substrate and an electro-optical display cell directly mounted on the substrate. The substrate has an integrated circuit chip on one side thereof, and a plurality of printed circuit leads connected to electrical terminals of the integrated circuit chip. The electro-optical display cell has a plurality of electric terminals formed in rows in alignment with terminal ends of said printed circuit leads. The electro-optical display cell is bonded to the one side of the substrate and the electric terminals of the display cell are bonded to the terminal ends of the printed circuit leads.
摘要翻译：一种固态钟表模块结构，包括塑料基板和直接安装在基板上的电光显示单元。基板的一侧具有集成电路芯片，并且多个印刷电路引线连接到集成电路芯片的电端子。所述电光显示单元具有与所述印刷电路引线的端子对准的多行电端子。电光显示单元被接合到基板的一侧，并且显示单元的电端子被接合到印刷电路引线的终端。

8. 发明授权

US06298014B1 Time information management system 有权
标题翻译：时间信息管理系统
公开(公告)号：US06298014B1
公开(公告)日：2001-10-02
申请号：US09214736
申请日：1999-01-11
申请人： Hiroyuki Kihara , Toshio Umemoto , Tomomi Murakami , Masahiro Sase
发明人： Hiroyuki Kihara , Toshio Umemoto , Tomomi Murakami , Masahiro Sase
IPC分类号： G04C1300
CPC分类号： G04R20/08
摘要： A time information management system with a simple configuration that instantaneously causes the individual time information of a plurality of timekeeping means within a prescribed area to coincide with standard time information, is formed by time information signal generating means that generates time information that includes standard time information, a time information adjusting means that includes within it a first timekeeping means, receives a time information signal, and outputs time information of the timekeeping means, and second timekeeping means 5-1, 5-2, . . . , 5-n that are disposed in an area surrounding the time information adjusting means 3, the time information adjusting means 3 including a standard time information extraction means for extracting standard time information from the time information signal of the time information signal generating means 2, a standard time correcting means 7 that corrects the first timekeeping means 4 within the time information adjusting means 3 to the standard time information, and a time information output means 8 that causes output of the standard time from the first timekeeping means 4, the standard time being received by the second timekeeping means and the kept time stored in the second timekeeping means being corrected based on the standard time.
摘要翻译：具有简单配置的时间信息管理系统由时间信息信号产生装置形成，该时间信息管理系统使得产生包含标准时间信息的时间信息的时间信息信号生成装置形成了将规定区域内的多个计时装置的各个时间信息立即地与标准时间信息一致的简单结构时间信息调整装置，其中包括第一计时装置，接收时间信息信号，并输出计时装置的时间信息和第二计时装置5-1,5-2，...。。。，5-n，时间信息调整装置3，其包括标准时间信息提取装置，用于从时间信息信号发生装置2的时间信息信号中提取标准时间信息，标准时间校正装置7，其将时间信息调整装置3内的第一计时装置4校正为标准时间信息;以及时间信息输出装置8，其从第一计时装置4输出标准时间，标准时间由第二计时装置接收并且基于标准时间校正存储在第二计时装置中的保持时间。

9. 发明授权

US5703837A Watch with light transmitting type display plate 失效
标题翻译：手表带透光型显示板
公开(公告)号：US5703837A
公开(公告)日：1997-12-30
申请号：US549702
申请日：1995-11-15
申请人： Toshio Umemoto , Masami Fukuda , Kenji Shimoda , Yasuo Kitajima , Isamu Kobayashi , Yurie Udou
发明人： Toshio Umemoto , Masami Fukuda , Kenji Shimoda , Yasuo Kitajima , Isamu Kobayashi , Yurie Udou
IPC分类号： G04B19/12 , G04B19/14 , G04B19/30 , G04C10/02 , G04C17/00 , G04G9/00 , G04B19/06
CPC分类号： G04C10/02 , G04B19/12 , G04B19/14 , G04B19/30 , G04C17/00 , G04G9/0041
摘要： A light transmitting type display plate 5 is arranged above a cell 2 such as an EL element or a solar cell or the like, and the display plate 5 is fixed to the support member 4 through the engagement of a positioning section 5b formed on the light transmitting type display plate 5 with a positioning section 4b formed on a support member 4. In the case where the light transmitting type display plate is a transparent plate 5, a spacer 6 or the like forms a gap 7 between the cell 2 and the transparent plate 5.
摘要翻译： PCT No.PCT / JP95 / 00188 Sec。 371日期：1995年11月15日 102（e）1995年11月15日日期PCT 1995年2月10日提交PCT公布。公开号WO95 / 27234 日期：1995年10月12日透光型显示板5配置在诸如EL元件或太阳能电池等的电池2的上方，显示板5通过定位部 5b形成在透光型显示板5上，其具有形成在支撑构件4上的定位部分4b。在透光型显示板是透明板5的情况下，间隔件6等在电池2和透明板5。

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