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1. 发明申请

US20140275083A1 3-PYRIMIDIN-4-YL-OXAZOLIDIN-2-ONES AS INHIBITORS OF MUTANT IDH 审中-公开
标题翻译： 3-PYRIMIDIN-4-YL-OXAZOLIDIN-2-ONES作为突变体IDH的抑制剂
公开(公告)号：US20140275083A1
公开(公告)日：2014-09-18
申请号：US14208015
申请日：2014-03-13
申请人： Thomas Raymond CAFERRO , Zhuoliang CHEN , Young Shin CHO , Abran Q. COSTALES , Julian Roy LEVELL , Gang LIU , James R. MANNING , Martin SENDZIK , Cynthia SHAFER , Michael David SHULTZ , James SUTTON , Yaping WANG , Qian ZHAO
发明人： Thomas Raymond CAFERRO , Zhuoliang CHEN , Young Shin CHO , Abran Q. COSTALES , Julian Roy LEVELL , Gang LIU , James R. MANNING , Martin SENDZIK , Cynthia SHAFER , Michael David SHULTZ , James SUTTON , Yaping WANG , Qian ZHAO
IPC分类号： C07D413/04 , A61K31/5377 , C07D417/14 , C07D413/14 , A61K31/506
CPC分类号： C07D413/14 , A61K31/506 , A61K31/5377 , A61K45/06 , C07D413/04 , C07D417/14
摘要： The invention is directed to a formula (I): or a pharmaceutically acceptable salt thereof, wherein R1, R2a, R2b and R3-R7 are herein. The invention is also directed to compositions containing a compound of formula (I) and to the use of such compounds in the inhibition of mutant IDH proteins having a neomorphic activity. The invention is further directed to the use of a compound of formula (I) in the treatment of diseases or disorders associated with such mutant IDH proteins including, but not limited to, cell-proliferation disorders, such as cancer.
摘要翻译：本发明涉及式（I）：或其药学上可接受的盐，其中R1，R2a，R2b和R3-R7为本文。本发明还涉及含有式（I）化合物的组合物以及这些化合物在抑制具有新形态活性的突变体IDH蛋白质中的用途。本发明还涉及式（I）化合物在治疗与这种突变体IDH蛋白相关的疾病或病症中的用途，包括但不限于细胞增殖病症如癌症。

2. 发明申请

US20160318915A1 3-PYRIMIDIN-4-YL-OXAZOLIDIN-2-ONES AS INHIBITORS OF MUTANT IDH 有权
标题翻译： 3-PYRIMIDIN-4-YL-OXAZOLIDIN-2-ONES作为突变体IDH的抑制剂
公开(公告)号：US20160318915A1
公开(公告)日：2016-11-03
申请号：US15209731
申请日：2016-07-13
申请人： Thomas Raymond CAFERRO , Zhuoliang CHEN , Young Shin CHO , Abran Q. COSTALES , Julian Roy LEVELL , Gang LIU , James R. MANNING , Martin SENDZIK , Cynthia SHAFER , Michael David SHULTZ , James Clifford SUTTON , Yaping WANG , Qian ZHAO
发明人： Thomas Raymond CAFERRO , Zhuoliang CHEN , Young Shin CHO , Abran Q. COSTALES , Julian Roy LEVELL , Gang LIU , James R. MANNING , Martin SENDZIK , Cynthia SHAFER , Michael David SHULTZ , James Clifford SUTTON , Yaping WANG , Qian ZHAO
IPC分类号： C07D413/14 , C07D413/04 , C07D417/14
CPC分类号： C07D413/14 , A61K31/506 , A61K31/5377 , A61K45/06 , C07D413/04 , C07D417/14
摘要： The invention is directed to a formula (I): or a pharmaceutically acceptable salt thereof, wherein R1, R2a, R2b and R3-R7 are herein. The invention is also directed to compositions containing a compound of formula (I) and to the use of such compounds in the inhibition of mutant IDH proteins having a neomorphic activity. The invention is further directed to the use of a compound of formula (I) in the treatment of diseases or disorders associated with such mutant IDH proteins including, but not limited to, cell-proliferation disorders, such as cancer.
摘要翻译：或其药学上可接受的盐，其中R1，R2a，R2b和R3-R7为本文。本发明还涉及含有式（I）化合物的组合物以及这些化合物在抑制具有新形态活性的突变体IDH蛋白质中的用途。本发明还涉及式（I）化合物在治疗与这种突变体IDH蛋白相关的疾病或病症中的用途，包括但不限于细胞增殖病症如癌症。

3. 发明申请

US20200351589A1 SURROUND-SCREEN SPEAKER ARRAY AND THE FORMATION METHOD OF VIRTUAL SOUND SOURCE 审中-公开
公开(公告)号：US20200351589A1
公开(公告)日：2020-11-05
申请号：US16758854
申请日：2018-09-30
申请人： Qian ZHAO , Jianguo ZHENG
发明人： Qian ZHAO , Jianguo ZHENG
IPC分类号： H04R5/02 , H04R1/26 , H04R1/40
摘要： The present disclosure is related to a surround-screen speaker array and a formation method of sound sources. The surround-screen speaker array includes a plurality of speaker subarrays that are disposed around a sound-proof screen tightly and uniformly. The speaker subarrays disposed around the sound-proof screen successfully provides a solution to reinforcement sound of a main sound channel for a movie screen that adopts a sound-proof material. Therefore, it is possible that the sound-proof screen can be used as the movie screen.

4. 发明申请

US20090006709A1 PCI EXPRESS INTERFACE 有权
标题翻译： PCI EXPRESS接口
公开(公告)号：US20090006709A1
公开(公告)日：2009-01-01
申请号：US12112079
申请日：2008-04-30
申请人： Qian ZHAO , Hao CHEN
发明人： Qian ZHAO , Hao CHEN
IPC分类号： G06F3/00
CPC分类号： G06F13/409 , G06F2213/0026 , G06F2213/0042
摘要： The present invention discloses a PCI Express interface compatible with USB interface comprising a power supply terminal and a ground terminal, in which four data terminals include two data transmitting terminals and two data receiving terminals, characterized in that the power supply terminal and the ground terminal of said interface coincide with the corresponding terminals of USB interface specification, two of said four data terminals are guaranteed to have their positions and widths overlaid with the position of terminal D+ in USB interface specification and not with the position of terminal D− in USB interface specification, and the other two data terminals are guaranteed to have their positions and widths overlaid with the position of terminal D− in USB interface specification and not with the position of terminal D+ in USB interface specification. The PCI Express interface compatible with USB interface can provide a data transmission rate up to 3 Gb/S according to PCI Express interface specification and support to the conventional USB peripheral devices without any modification on them. It further has the advantages of small-sized outline and convenience in use.
摘要翻译：本发明公开了一种与USB接口兼容的PCI Express接口，包括电源端子和接地端子，其中四个数据端子包括两个数据发送端子和两个数据接收端子，其特征在于，电源端子和接地端子所述接口与USB接口规范的相应端子一致，所述四个数据终端中的两个被保证具有与USB接口规范中的终端D +的位置重叠的位置和宽度，而不是在USB接口规范中的终端D的位置，其他两个数据终端保证其位置和宽度与USB接口规范中终端D-的位置重叠，而不是USB接口规范中终端D +的位置。与USB接口兼容的PCI Express接口可以根据PCI Express接口规范提供高达3 Gb / S的数据传输速率，并支持传统的USB外设，无需任何修改。它具有使用尺寸小，使用方便的优点。

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