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1. 发明授权

US06422187B1 Variable valve mechanism having an eccentric-driven frame 有权
公开(公告)号：US06422187B1
公开(公告)日：2002-07-23
申请号：US09755364
申请日：2001-01-05
申请人： Thomas H. Fischer , William R. Haslett
发明人： Thomas H. Fischer , William R. Haslett
IPC分类号： F01L1300
摘要： A variable valve mechanism includes an elongate input shaft having a central axis. An input cam lobe is disposed on the input shaft and is eccentric relative to the central axis. A guide member is pivotally mounted on the input shaft. A frame is disposed in engagement with the input cam lobe, and is pivotally and slidably coupled to the guide member. A link has a first end pivotally coupled to the frame. An output cam is pivotally mounted on the input shaft. The output cam is pivotally coupled to a second end of the link arm. The output cam is configured for oscillating engagement of a roller of a roller finger follower.

2. 发明授权

US06382153B1 Partial internal guide for curved helical compression spring 失效
标题翻译：弯曲螺旋压缩弹簧的部分内部导轨
公开(公告)号：US06382153B1
公开(公告)日：2002-05-07
申请号：US09832582
申请日：2001-04-11
申请人： Jeffrey D. Rohe , Ronald J. Pierik , Thomas H. Fischer , William R. Haslett
发明人： Jeffrey D. Rohe , Ronald J. Pierik , Thomas H. Fischer , William R. Haslett
IPC分类号： F01L1300
CPC分类号： F01L1/34 , F01L2105/00
摘要： A variable valve actuating comprising a spring guide for use with a curved spring includes an elongate, curved guide member having a centerline. The centerline has a centerline curvature that is substantially equal to the radius of curvature of the curved spring. The guide member has a first side having a side curvature. The side curvature is substantially equal to a curvature of the curved inside surfaces of the coils of the curved spring. The guide member is configured for being disposed within the curved spring such that the coils thereof substantially surround a periphery of the guide member.
摘要翻译：包括与弯曲弹簧一起使用的弹簧引导件的可变气门致动器包括具有中心线的细长弯曲引导构件。中心线具有基本上等于弯曲弹簧的曲率半径的中心线曲率。引导构件具有侧曲率的第一侧。侧曲率基本上等于弯曲弹簧的线圈的弯曲内表面的曲率。引导构件被配置为设置在弯曲弹簧内，使得其线圈基本上围绕引导构件的周边。

3. 发明授权

US09867782B2 Spray-dried blood products and methods of making same 有权
公开(公告)号：US09867782B2
公开(公告)日：2018-01-16
申请号：US13262931
申请日：2010-04-06
申请人： Thomas H. Fischer , Joseph A. DaCorta , Michael Lawrence Galiger
发明人： Thomas H. Fischer , Joseph A. DaCorta , Michael Lawrence Galiger
IPC分类号： A61K9/16 , A61F13/00 , A61K9/00 , A61K35/16 , A61K35/19 , A61L26/00
CPC分类号： A61K9/1688 , A61F13/00063 , A61F2013/00306 , A61F2013/00472 , A61F2013/00927 , A61K9/0026 , A61K35/16 , A61K35/19 , A61L26/0047 , A61L26/0057 , A61L26/0076
摘要： The present invention is directed to a method of preparing dehydrated blood products, comprising the steps of: (a) providing a hydrated blood product; (b) spray-drying the hydrated blood product to produce a dehydrated blood product, as well as dehydrated blood products made by the method. The present invention is directed to a method of treating a patient suffering from a blood-related disorder, comprising the steps of: (a) rehydrating a therapeutic amount of the dehydrated blood products to produce a rehydrated therapeutic composition; and (b) administering the rehydrated therapeutic composition to the patient. The present invention is directed to a bandage or surgical aid comprising the dehydrated blood products described above.

4. 发明申请

US20090266322A1 Vane-type cam phaser having staged locking pins to assist intermediate position locking 有权
标题翻译：叶片式凸轮移相器具有分级锁定销以辅助中间位置锁定
公开(公告)号：US20090266322A1
公开(公告)日：2009-10-29
申请号：US12150381
申请日：2008-04-28
申请人： Thomas H. Fischer
发明人： Thomas H. Fischer
IPC分类号： F01L1/344
CPC分类号： F01L1/3442 , F01L2001/34469 , F01L2001/34483
摘要： A vane-type camshaft phaser including a bias spring to urge the rotor toward an intermediate locking position from any rotational position retarded of the locking position. The rotor comprises non-coaxially acting primary and secondary locking pins for mating with primary and secondary locking pin seats in the phaser stator. The primary seat is elongated and is readily located by the primary locking pin to provide a first limit to the rotor phase angle authority in the retard direction. Camshaft torque reversals cause the rotor phase angle to dither. With each torque reversal the secondary locking pin passes over its seat, allowing multiple opportunities for re-engagement. The clearance of the secondary locking pin to its seat defines the rotary lash in the phaser.
摘要翻译：一种叶片式凸轮轴相位器，其包括偏置弹簧，以从延迟锁定位置的任何旋转位置将转子推向中间锁定位置。转子包括非同轴作用的初级和次级锁定销，用于与相位器定子中的主要和次级锁定销座配合。主座椅是细长的，并且容易地由主锁定销定位，以在延迟方向上为转子相角权限提供第一限制。凸轮轴扭矩反转导致转子相位角抖动。通过每个扭矩反转，辅助锁定销通过其座椅，允许重新接合的多个机会。辅助锁定销到其座椅的间隙限定了移相器中的旋转间隙。

5. 发明申请

US20090053288A1 Hemostatic woven fabric 审中-公开
标题翻译：止汗梭织物
公开(公告)号：US20090053288A1
公开(公告)日：2009-02-26
申请号：US12228490
申请日：2008-08-13
申请人： E. Stan Eskridge, JR. , Thomas H. Fischer , James V. Snipes
发明人： E. Stan Eskridge, JR. , Thomas H. Fischer , James V. Snipes
IPC分类号： A61K9/70 , D03D13/00 , A61K38/48 , A61P7/04 , A61F13/15
CPC分类号： D03D15/00 , A61F13/00034 , A61F13/00063 , A61F2013/00238 , A61F2013/00472 , A61F2013/00548 , A61F2013/00902 , A61F2013/0091 , A61L15/44 , A61L2300/252 , A61L2300/418 , A61L2300/45 , A61L2300/64 , D03D13/004 , D03D15/0011 , D03D15/0077 , D10B2101/06 , D10B2201/01 , D10B2201/10 , D10B2401/063 , D10B2509/00 , Y10T442/3179
摘要： The present invention is directed to a woven fabric having the modified crowsfoot weave pattern shown in FIGS. 2A and 2B. The present invention is directed to a woven fabric comprising about 65 wt % fiberglass yarn and about 35 wt % bamboo yarn, the woven fabric (1) being about 15.0 ounces per square yard (OSY); (2) having a thread count of about 760; and (3) having the modified crowsfoot weave pattern shown in FIGS. 2A and 2B. Additional ingredients may also be added to the woven fabrics of the invention to enhance the hemostatic properties.
摘要翻译：本发明涉及一种具有如图1和2所示的改进的乌布脚印编织图案的机织织物。图2A和2B。本发明涉及一种包含约65重量％玻璃纤维纱和约35重量％竹纱的机织织物，织物（1）为约15.0盎司/平方码（OSY）; （2）线数约760; 和（3）具有图1和图2所示的改进的乌布脚印编织图案。图2A和2B。另外的成分也可以添加到本发明的机织织物中以增强止血性能。

6. 发明申请

US20080286366A1 Delivery of micro- and nanoparticles with blood platelets 有权
标题翻译：用血小板递送微量和纳米颗粒
公开(公告)号：US20080286366A1
公开(公告)日：2008-11-20
申请号：US12150562
申请日：2008-04-29
申请人： Thomas H. Fischer , E. Stan Eskridge, JR.
发明人： Thomas H. Fischer , E. Stan Eskridge, JR.
IPC分类号： A61K9/14 , C12N5/02 , A61K35/14 , A61K38/16 , A61K31/7088 , A61K33/26
CPC分类号： C12N5/0644 , A61K31/7088 , A61K33/26 , A61K35/12 , A61K35/19 , A61K38/16 , A61K38/36 , A61K47/6901 , A61K49/1887 , A61K49/1896 , A61K49/222 , B82Y5/00
摘要： The invention is directed to platelets containing micron or nanometer size particles wherein the micron or nanometer sized particles comprises an active agent. The invention is also directed to a pharmaceutical composition comprising a pharmaceutically acceptable carrier and the above platelets. The invention is further directed to methods of delivering the micron or nanometer size particles containing an active agent to a site of interest in a patient.
摘要翻译：本发明涉及含有微米或纳米尺寸颗粒的血小板，其中微米或纳米尺寸的颗粒包含活性剂。本发明还涉及包含药学上可接受的载体和上述血小板的药物组合物。本发明进一步涉及将含有活性剂的微米或纳米尺寸颗粒输送到患者感兴趣部位的方法。

7. 发明授权

US07305951B2 Two-step roller finger follower 有权
标题翻译：两步辊手指随动
公开(公告)号：US07305951B2
公开(公告)日：2007-12-11
申请号：US11125360
申请日：2005-05-09
申请人： Hermes A. Fernandez , Andrew J. Lipinski , Nick J. Hendriksma , Thomas H. Fischer , Timothy W. Kunz
发明人： Hermes A. Fernandez , Andrew J. Lipinski , Nick J. Hendriksma , Thomas H. Fischer , Timothy W. Kunz
IPC分类号： F01L1/18
CPC分类号： F01L13/0036 , F01L1/185 , F01L2001/186 , F01L2001/467 , Y10T74/20882 , Y10T74/2107
摘要： A two-step roller finger follower having a high-lift follower portion that rotates relative to a low-lift follower portion about a pivot shaft, including a lost-motion compression spring disposed in a linear bore formed in the high-lift portion to exert force against an curved pad on the back side of the valve pallet of the low-lift portion. The spring is retained and guided in its bore by a spring retainer having a planar bottom for engaging the curved pad. Preferably the retainer is a cup positioned in the spring bore such that the stroke of the cup is limited, to prevent leak-down of the associated hydraulic lash adjuster. Driving the spring by a linear-acting retainer in a linear bore causes the spring to be compressed linearly, resulting in a highly stable and predictable spring rate.
摘要翻译：一种具有高升力从动件部分的两步辊指随动件，其相对于低升力从动件部分围绕枢转轴线旋转，包括设置在形成在高升力部分中的线性孔中的迷失运动压缩弹簧，以施加力抵靠低升程部分的阀托板的后侧上的弯曲垫。弹簧通过具有用于接合弯曲垫的平坦底部的弹簧保持器在其孔中保持和引导。优选地，保持器是定位在弹簧孔中的杯，使得杯的行程受到限制，以防止相关联的液压间隙调节器的泄漏。在线性孔中通过线性作用的保持器驱动弹簧使得弹簧被线性地压缩，导致高度稳定和可预测的弹簧刚度。

8. 发明授权

US06938873B2 Compound valve assembly for controlling high and low oil flow and pressure 有权
标题翻译：用于控制高低油流量和压力的复合阀组件
公开(公告)号：US06938873B2
公开(公告)日：2005-09-06
申请号：US10724664
申请日：2003-12-01
申请人： Thomas H. Fischer
发明人： Thomas H. Fischer
IPC分类号： F01L1/26 , F01L1/344 , F01L13/00 , F02M39/00
CPC分类号： F01L13/0005 , F01L1/267 , F01L1/344 , F01L13/0015 , F01L13/0031 , F01L13/0036 , F01L2001/34426 , F01L2001/3443
摘要： A compound valve assembly for controlling oil flow includes a first and a second valve. The first valve is a pressure relief valve including a spring-biased plunger in a side gallery opening off a primary oil supply gallery leading to a pressure-actuated device. The relief spring allows oil above a predetermined pressure to displace the plunger and to be returned to an oil sump. The side gallery is closable by a secondary valve seat and a solenoid-actuated valve head. A passage through the plunger leads to the second valve seat. When the solenoid is deactivated, oil flows through the passage, through the second valve, and is returned to the sump. When high pressure is desired at the device, the solenoid closes the second valve. Captive oil assumes the same pressure as the supply pressure, and the relief valve function is disabled, causing high pressure oil to flow to the device.
摘要翻译：用于控制油流的复合阀组件包括第一阀和第二阀。第一阀是一个压力释放阀，其包括在通过压力致动装置的主要油供给通道开口的侧面库中的弹簧偏置柱塞。释放弹簧允许高于预定压力的油移动柱塞并返回到油底壳。侧廊可由次阀座和电磁阀驱动的阀头关闭。通过柱塞的通道通向第二阀座。当螺线管停用时，油流过通道，通过第二阀，并返回到贮槽。当设备需要高压时，电磁阀关闭第二个阀门。吸油量与供气压力相同，安全阀功能不起作用，导致高压油流入设备。

9. 发明授权

US06904937B2 Switchable fluid control valve system 失效
标题翻译：可切换流体控制阀系统
公开(公告)号：US06904937B2
公开(公告)日：2005-06-14
申请号：US10712235
申请日：2003-11-13
申请人： Thomas H. Fischer
发明人： Thomas H. Fischer
IPC分类号： F01L1/34 , F01L13/00 , F15B13/04 , F15B13/044 , F15B21/08 , F15B13/043
CPC分类号： F15B13/044 , F01L1/34 , F01L13/0005 , F01L13/0015 , F01L2001/34426 , F01L2001/3443 , F15B13/0402 , F15B21/082 , Y10T137/86614
摘要： A switchable fluid control valve assembly having a regulating spool and a pilot spool disposed within a common bore. A regulating spring urges the regulating spool toward a rest position wherein an oil supply port is fully uncovered. Supply oil entering the assembly causes the regulating spool to assume a position wherein oil flow is throttled to a downstream pressure insufficient to activate an associated valve deactivation mechanism but sufficient to provide lubrication to the engine. When activation of the mechanism is desired, a solenoid moves the pilot spool wherein oil at full pressure is engaged against the regulating spool, de-throttling the flow of oil to the mechanism. When the solenoid is again deactivated, a dump port is opened into the oil flow path, immediately reducing the pressure on the regulating spool which then moves to eclipse the supply port and open a path from the mechanism to drain.
摘要翻译：一种可切换流体控制阀组件，其具有调节阀芯和设置在公共孔内的先导阀芯。调节弹簧将调节滑阀推向静止位置，其中供油口完全未被覆盖。进入组件的供油导致调节阀芯处于油位被节流到下游压力的位置，该下压压力不足以启动相应的阀停用机构，但足以向发动机提供润滑。当需要启动机构时，螺线管使先导阀芯移动，其中全压下的油接合调节阀芯，将油流除油到机构。当螺线管再次停用时，将泄油口打开到油流通道中，立即减小调节阀芯上的压力，然后移动以抵消供油口并打开从机构排出的路径。

10. 发明授权

US06758184B1 Method and apparatus for reducing oscillatory camshaft torque in an internal combustion engine 失效
标题翻译：用于减少内燃机中的振荡凸轮轴扭矩的方法和装置
公开(公告)号：US06758184B1
公开(公告)日：2004-07-06
申请号：US10454895
申请日：2003-06-05
申请人： Jongmin Lee , John Krieg , Thomas H. Fischer
发明人： Jongmin Lee , John Krieg , Thomas H. Fischer
IPC分类号： F01M100
CPC分类号： F01M1/02 , F01M2001/023 , F01M2001/0261
摘要： A peristaltic piston pump driven by a dedicated pump cam disposed on a camshaft of an engine. A plurality of valve-opening cams are also disposed along the camshaft. The pump cam has a plurality of lobes equal in number to the number of valve cams and each pump lobe is disposed at 180° from a valve cam lobe such that the camshaft valve torque and secondary oil pump camshaft torque partially cancel, reducing overall camshaft torque oscillation. The pump includes a lost-motion shuttle and spring to permit continuous response of the pump to the cam.
摘要翻译：由设置在发动机的凸轮轴上的专用泵凸轮驱动的蠕动活塞泵。多个开阀凸轮也沿着凸轮轴布置。泵凸轮具有与阀凸轮的数量相等的多个凸角，并且每个泵凸起设置在与凸轮轴凸角成180°的位置，使得凸轮轴阀转矩和辅助油泵凸轮轴扭矩部分抵消，从而减小整体凸轮轴扭矩振荡。该泵包括一个空转梭和弹簧，以允许泵连续响应于凸轮。

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