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1. 发明授权

US5810792A Locking blunt cannula 失效
标题翻译：锁死钝插管
公开(公告)号：US5810792A
公开(公告)日：1998-09-22
申请号：US627881
申请日：1996-04-03
申请人： Thomas F. Fangrow, Jr. , Daniel J. Wait , George A. Lopez , David Charles Arnold , Dennis M. Bui , Kevin Barry Hanly
发明人： Thomas F. Fangrow, Jr. , Daniel J. Wait , George A. Lopez , David Charles Arnold , Dennis M. Bui , Kevin Barry Hanly
IPC分类号： A61M39/02 , A61M39/00 , A61M39/04 , A61M39/10 , A61M25/00
CPC分类号： A61M39/1011 , A61M39/045 , A61M2039/042 , A61M2039/1033
摘要： Disclosed is a medical connector for introducing medication to a patient in a safe, convenient way by releasably locking an influent fluid line to a receiving port, and method of manufacturing the same. The connector comprises a cannula recessed within a cavity defined by a housing. The housing contains a retaining ridge and gripping members to prevent accidental disconnection of the connector for the port.
摘要翻译：公开了一种医疗连接器，其以安全，方便的方式将患者的药物引入患者，通过将流体线可释放地锁定到接收口，以及制造该流体线的方法。连接器包括凹入由壳体限定的空腔内的插管。壳体包含保持脊和夹持构件，以防止端口连接器意外断开。

2. 外观设计

USD393722S Locking blunt cannula 失效
公开(公告)号：USD393722S
公开(公告)日：1998-04-21
申请号：US52594
申请日：1996-04-04
申请人： Thomas F. Fangrow, Jr. , Daniel J. Wait , George A. Lopez , David Charles Arnold , Dennis M. Bui , Kevin Barry Hanly
设计人： Thomas F. Fangrow, Jr. , Daniel J. Wait , George A. Lopez , David Charles Arnold , Dennis M. Bui , Kevin Barry Hanly

3. 发明授权

US06932795B2 Positive flow valve 有权
标题翻译：正流阀
公开(公告)号：US06932795B2
公开(公告)日：2005-08-23
申请号：US10163719
申请日：2002-06-05
申请人： George A. Lopez , Thomas F. Fangrow, Jr. , David C. Arnold , Bruce M. Hubrecht , Alison D. Brummett , Thomas J. Gustus , Dennis M. Bui
发明人： George A. Lopez , Thomas F. Fangrow, Jr. , David C. Arnold , Bruce M. Hubrecht , Alison D. Brummett , Thomas J. Gustus , Dennis M. Bui
IPC分类号： A61M39/00 , A61M5/00 , A61M39/04 , A61M39/26
CPC分类号： A61M39/26 , A61M39/045 , A61M2039/0072 , A61M2039/263 , A61M2039/266 , A61M2039/267
摘要： A closed system, spikeless, positive-flow valve device includes a body defining an internal cavity. At the proximal end of the body is an opening which is preferably sufficiently large to receive an ANSI standard tip of a medical implement. The valve includes a plastic, resilient silicon seal which fills the upper cavity and opening with an oval seal cap having a slit. The opening presses the oval seal cap to keep the slit closed in the decompressed state. The slit opens as the nose of the medical implement compresses the seal into the cavity and the seal cap is free from the opening. The housing also includes a fluid space which facilitates fluid flow between the medical implement and a catheter tip. The fluid space within the valve automatically and reversibly increases upon insertion of the medical implement into the cavity and decreases upon withdrawal of the medical implement, such that a positive flow from the valve toward the catheter tip is effected upon withdrawal of the medical implement, thereby preventing a flow of blood from a patient into the catheter when the medical implement is removed from the valve.
摘要翻译：封闭系统，无尖锐的正流阀装置包括限定内腔的主体。在身体的近端处是优选地足够大以接收医疗器具的ANSI标准尖端的开口。该阀包括塑料弹性硅密封件，其填充上腔体并用具有狭缝的椭圆形密封盖开口。开口按压椭圆形密封帽，使狭缝在解压缩状态下闭合。当医疗器具的鼻子将密封件压入空腔并且密封帽没有开口时，缝隙打开。壳体还包括便于流体在医疗器具和导管尖端之间流动的流体空间。当医疗器具插入空腔中时，阀门内的流体空间自动地和可逆地增加，并且在医疗器具撤回时减小，使得从医疗器具撤回时从阀门朝向导管尖端的正向流动被实现，从而当医疗器具从阀门移除时，防止血液从患者流入导管。

4. 发明授权

US06428520B1 Positive-flow valve 有权
标题翻译：正流阀
公开(公告)号：US06428520B1
公开(公告)日：2002-08-06
申请号：US09411988
申请日：1999-10-04
申请人： George A. Lopez , Thomas F. Fangrow, Jr. , David C. Arnold , Bruce M. Hubrecht , Alison D. Brummett , Thomas J. Gustus , Dennis M. Bui
发明人： George A. Lopez , Thomas F. Fangrow, Jr. , David C. Arnold , Bruce M. Hubrecht , Alison D. Brummett , Thomas J. Gustus , Dennis M. Bui
IPC分类号： A61M500
CPC分类号： A61M39/26 , A61M39/045 , A61M2039/0072 , A61M2039/263 , A61M2039/266 , A61M2039/267
摘要： A closed system, spikeless, positive-flow valve device includes a body defining an internal cavity. At the proximal end of the body is an opening which is preferably sufficiently large to receive an ANSI standard tip of a medical implement. The valve includes a plastic, resilient silicon seal which fills the upper cavity and opening with an oval seal cap having a slit. The opening presses the oval seal cap to keep the slit closed in the decompressed state. The slit opens as the nose of the medical implement compresses the seal into the cavity and the seal cap is free from the opening. The housing also includes a fluid space which facilitates fluid flow between the medical implement and a catheter tip. The fluid space within the valve automatically and reversibly increases upon insertion of the medical implement into the cavity and decreases upon withdrawal of the medical implement, such that a positive flow from the valve toward the catheter tip is effected upon withdrawal of the medical implement, thereby preventing a flow of blood from a patient into the catheter when the medical implement is removed from the valve.
摘要翻译：封闭系统，无尖锐的正流阀装置包括限定内腔的主体。在身体的近端处是优选地足够大以接收医疗器具的ANSI标准尖端的开口。该阀包括塑料弹性硅密封件，其填充上腔体并用具有狭缝的椭圆形密封盖开口。开口按压椭圆形密封帽，使狭缝在解压缩状态下闭合。当医疗器具的鼻子将密封件压入空腔并且密封帽没有开口时，缝隙打开。壳体还包括便于流体在医疗器具和导管尖端之间流动的流体空间。当医疗器具插入空腔中时，阀门内的流体空间自动地和可逆地增加，并且在医疗器具撤回时减小，使得从医疗器具撤回时从阀门朝向导管尖端的正向流动被实现，从而当医疗器具从阀门移除时，防止血液从患者流入导管。

5. 发明授权

US08522832B2 Fluid transfer devices and methods of use 有权
公开(公告)号：US08522832B2
公开(公告)日：2013-09-03
申请号：US12845548
申请日：2010-07-28
申请人： George A. Lopez , Thomas F. Fangrow, Jr. , Peter Leissling , Matthias Janssen
发明人： George A. Lopez , Thomas F. Fangrow, Jr. , Peter Leissling , Matthias Janssen
IPC分类号： B65B1/04 , A61B19/00
CPC分类号： A61J1/2096 , A61J1/10 , A61J1/201 , A61J1/2058 , A61J1/2062 , A61J1/2075 , A61J1/2082 , A61J1/2089 , A61J2200/76 , A61M39/22 , B67D3/0003 , Y10S604/905 , Y10T29/49826
摘要： Some embodiments disclosed herein related to a device for transferring precise amounts of fluid from at least one source container to a at least one target container. In some embodiments, the fluid is first transferred from the source container (e.g., a vial) through a connector to an intermediate measuring container (e.g., a syringe). In some embodiments air can pass through an air inlet and enter the vial to compensate for the volume of fluid withdrawn from the vial. An air check valve or a bag or a filter can prevent the fluid from escaping through the air inlet. The precisely measured amount of fluid can then be transferred from the intermediate measuring container to the target container (e.g., an IV bag). In some embodiments the connector can include a source check valve and a target check valve to direct fluid first from the source container to the intermediate measuring container and then from the intermediate measuring container to the target container. Some embodiments of the device can include a motor and a controller for automatically actuating a plunger of the syringe to transfer the desired amount of fluid.

6. 发明申请

US20110282302A1 MEDICAL CONNECTORS AND METHODS OF USE 有权
标题翻译：医用连接器及使用方法
公开(公告)号：US20110282302A1
公开(公告)日：2011-11-17
申请号：US13106781
申请日：2011-05-12
申请人： George A. Lopez , Thomas F. Fangrow, JR. , Bob Foret
发明人： George A. Lopez , Thomas F. Fangrow, JR. , Bob Foret
IPC分类号： A61M39/24 , A61M39/22
CPC分类号： A61M39/10 , A61M39/0613 , A61M39/16 , A61M39/26 , A61M2005/1588 , A61M2039/0063 , A61M2039/0633 , A61M2039/0686 , A61M2039/1072 , A61M2039/267 , A61M2205/02 , A61M2206/20 , F16L37/38 , Y10T137/9029
摘要： A medical connector for use in a fluid pathway includes a substantially transparent housing having a proximal end with a proximal opening and a distal end with a distal opening, and a cavity extending therebetween. The connector provides a substantially visible fluid flow path extending through a substantial portion of the connector.
摘要翻译：用于流体通道的医疗连接器包括基本上透明的壳体，其具有近端具有近端开口和具有远端开口的远端，以及在其间延伸的腔体。连接器提供延伸穿过连接器的大部分的基本上可见的流体流动路径。

7. 发明授权

US08758306B2 Medical connectors and methods of use 有权
标题翻译：医疗连接器和使用方法
公开(公告)号：US08758306B2
公开(公告)日：2014-06-24
申请号：US13106781
申请日：2011-05-12
申请人： George A. Lopez , Thomas F. Fangrow, Jr. , Bob Foret
发明人： George A. Lopez , Thomas F. Fangrow, Jr. , Bob Foret
IPC分类号： A61M5/00 , A61M39/00
CPC分类号： A61M39/10 , A61M39/0613 , A61M39/16 , A61M39/26 , A61M2005/1588 , A61M2039/0063 , A61M2039/0633 , A61M2039/0686 , A61M2039/1072 , A61M2039/267 , A61M2205/02 , A61M2206/20 , F16L37/38 , Y10T137/9029
摘要： A medical connector for use in a fluid pathway includes a substantially transparent housing having a proximal end with a proximal opening and a distal end with a distal opening, and a cavity extending therebetween. The connector provides a substantially visible fluid flow path extending through a substantial portion of the connector.
摘要翻译：用于流体通道的医疗连接器包括基本上透明的壳体，其具有近端具有近端开口和具有远端开口的远端，以及在其间延伸的腔体。连接器提供延伸穿过连接器的大部分的基本可见的流体流动路径。

8. 发明申请

US20110062703A1 FLUID TRANSFER DEVICES AND METHODS OF USE 有权
标题翻译：流体传递装置及其使用方法
公开(公告)号：US20110062703A1
公开(公告)日：2011-03-17
申请号：US12845548
申请日：2010-07-28
申请人： George A. Lopez , Thomas F. Fangrow, JR. , Peter Leissling , Matthias Janssen
发明人： George A. Lopez , Thomas F. Fangrow, JR. , Peter Leissling , Matthias Janssen
IPC分类号： F16L41/00 , B23P19/00
CPC分类号： A61J1/2096 , A61J1/10 , A61J1/201 , A61J1/2058 , A61J1/2062 , A61J1/2075 , A61J1/2082 , A61J1/2089 , A61J2200/76 , A61M39/22 , B67D3/0003 , Y10S604/905 , Y10T29/49826
摘要： Some embodiments disclosed herein related to a device for transferring precise amounts of fluid from at least one source container to a at least one target container. In some embodiments, the fluid is first transferred from the source container (e.g., a vial) through a connector to an intermediate measuring container (e.g., a syringe). In some embodiments air can pass through an air inlet and enter the vial to compensate for the volume of fluid withdrawn from the vial. An air check valve or a bag or a filter can prevent the fluid from escaping through the air inlet. The precisely measured amount of fluid can then be transferred from the intermediate measuring container to the target container (e.g., an IV bag). In some embodiments the connector can include a source check valve and a target check valve to direct fluid first from the source container to the intermediate measuring container and then from the intermediate measuring container to the target container. Some embodiments of the device can include a motor and a controller for automatically actuating a plunger of the syringe to transfer the desired amount of fluid.
摘要翻译：本文公开的一些实施例涉及用于将精确量的流体从至少一个源容器传送到至少一个目标容器的装置。在一些实施例中，首先将流体从源容器（例如，小瓶）通过连接器传送到中间测量容器（例如，注射器）。在一些实施例中，空气可以通过空气入口并进入小瓶以补偿从小瓶中取出的流体的体积。空气止回阀或袋或过滤器可以防止流体通过进气口逸出。然后将精确测量的流体量从中间测量容器转移到目标容器（例如，IV袋）。在一些实施例中，连接器可以包括源止回阀和目标止回阀，以将流体首先从源容器引导到中间测量容器，然后从中间测量容器引导到目标容器。该装置的一些实施例可以包括马达和控制器，用于自动致动注射器的柱塞以转移所需量的流体。

9. 发明授权

US08002765B2 Medical valve with fluid escape space 有权
标题翻译：医疗阀具有流体逃逸空间
公开(公告)号：US08002765B2
公开(公告)日：2011-08-23
申请号：US11417397
申请日：2006-05-03
申请人： George A. Lopez
发明人： George A. Lopez
IPC分类号： A61M25/16
CPC分类号： A61M39/10 , A61J2200/10 , A61M39/26 , A61M2039/1027 , A61M2039/1072 , A61M2039/262 , A61M2039/266 , A61M2039/267
摘要： A medical valve has a body and a flexible element. The body includes a wall structure defining an internal cavity having an inside and an outside. The body also has a proximal end and a distal end. The proximal end has an opening sufficiently large to receive a tip of a delivery end of a medical implement which transfers fluid through the delivery end. The body has a fluid escape space in its wall structure. The flexible element is adapted to be moved into a compressed state upon insertion of the tip of the medical implement into the opening. The flexible element is sufficiently resilient to return to a decompressed state upon removal of the tip of the medical implement from the opening. The fluid escape space is in fluid communication with the outside of the cavity when the seal is in its compressed state.
摘要翻译：医疗阀具有主体和柔性元件。主体包括限定具有内部和外部的内部空腔的壁结构。身体还具有近端和远端。近端具有足够大的开口，以接收医疗器具的输送端的尖端，其将流体传送通过输送端。身体在其壁结构中具有流体逸出空间。柔性元件适于在将医疗器具的尖端插入开口中时被移动到压缩状态。柔性元件具有足够的弹性，以便在从开口移除医疗器具的尖端时恢复到减压状态。当密封件处于其压缩状态时，流体逸出空间与空腔的外部流体连通。

10. 发明授权

US07717886B2 Medical valve and method of use 失效
公开(公告)号：US07717886B2
公开(公告)日：2010-05-18
申请号：US11417507
申请日：2006-05-03
申请人： George A. Lopez
发明人： George A. Lopez
IPC分类号： A61M5/00
CPC分类号： A61M5/14 , A61J2200/10 , A61M39/045 , A61M39/26 , A61M2039/262 , A61M2039/267 , A61M2205/32 , A61M2205/583 , A61M2205/6063 , F21K2/00 , Y10S604/905
摘要： A closed system, needleless valve device includes a generally tubular body defining an internal cavity. On the proximal end of the body there is an opening which is preferably sufficiently large to receive an ANSI standard tip of a medical implement. The distal end of the body has a generally tubular skirt. The valve also includes a hollow spike having a closed tip. The spike includes at least one longitudinal 18-gauge hole located distal the tip, and is seated inside the cavity such that the tip is below the proximal end of the body. An annular support cuff is connected to the spike which seals off a portion of the cavity of the body such that an upper cavity containing the tip is defined. The valve also includes a plastic, resilient silicone seal which fills the upper cavity and opening and covers the tip of the spike so as to present a flush surface. An adaptor enables the valve to be attached to a resealable container.

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