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1. 发明授权

US09205224B2 Infusion mechanism and method 有权
标题翻译：输液机制及方法
公开(公告)号：US09205224B2
公开(公告)日：2015-12-08
申请号：US12756400
申请日：2010-04-08
申请人： Therese O'Day , Frank J. Fischer, Jr. , Lindsay Koren , Mark Allen Magnuson , Richard Earl Luedemann , Shyam Kuppurathanam , Keith R. Milner
发明人： Therese O'Day , Frank J. Fischer, Jr. , Lindsay Koren , Mark Allen Magnuson , Richard Earl Luedemann , Shyam Kuppurathanam , Keith R. Milner
IPC分类号： A61M25/00 , A61M25/01 , A61M25/09
CPC分类号： A61M25/003 , A61M25/002 , A61M25/007 , A61M25/0108 , A61M2025/004 , A61M2025/0073 , A61M2025/0079 , A61M2025/0183 , A61M2025/09175
摘要： An infusion mechanism for treating an intraluminal site in a patient includes an infusion catheter having an elongate body with a proximal body end defining at least one fluid supply orifice, and a distal body end. The elongate body defines a high head loss lumen in fluid communication with a first set of side ports defining a proximal infusion zone. The elongate body further defines a low head loss lumen in fluid communication with a second set of side ports defining a distal infusion zone.
摘要翻译：用于治疗患者的管腔内部位的输注机构包括具有细长体的输注导管，其具有限定至少一个流体供应孔的近端体端和远端本体端。细长体限定了与限定近端输注区的第一组侧端口流体连通的高头损失腔。细长体进一步限定与限定远端输注区的第二组侧端口流体连通的低头损失腔。

2. 发明申请

US20110251588A1 Infusion Mechanism And Method 有权
标题翻译：输液机制与方法
公开(公告)号：US20110251588A1
公开(公告)日：2011-10-13
申请号：US12756400
申请日：2010-04-08
申请人： Therese O'Day , Frank J. Fischer, JR. , Lindsay Koren , Mark Allen Magnuson , Richard Earl Luedemann , Shyam Kuppurathanam , Keith R. Milner
发明人： Therese O'Day , Frank J. Fischer, JR. , Lindsay Koren , Mark Allen Magnuson , Richard Earl Luedemann , Shyam Kuppurathanam , Keith R. Milner
IPC分类号： A61M25/00 , A61M25/09
CPC分类号： A61M25/003 , A61M25/002 , A61M25/007 , A61M25/0108 , A61M2025/004 , A61M2025/0073 , A61M2025/0079 , A61M2025/0183 , A61M2025/09175
摘要： An infusion mechanism for treating an intraluminal site in a patient includes an infusion catheter having an elongate body with a proximal body end defining at least one fluid supply orifice, and a distal body end. The elongate body defines a high head loss lumen in fluid communication with a first set of side ports defining a proximal infusion zone. The elongate body further defines a low head loss lumen in fluid communication with a second set of side ports defining a distal infusion zone.
摘要翻译：用于治疗患者的管腔内部位的输注机构包括具有细长体的输注导管，其具有限定至少一个流体供应孔的近端体端和远端本体端。细长体限定了与限定近端输注区的第一组侧端口流体连通的高头损失腔。细长体进一步限定与限定远端输注区的第二组侧端口流体连通的低头损失腔。

3. 发明授权

US09314589B2 Method of treating an intravascular site in a patient, and thrombolysis catheter therefor 有权
标题翻译：治疗患者血管内部位的方法及其溶栓导管
公开(公告)号：US09314589B2
公开(公告)日：2016-04-19
申请号：US13695915
申请日：2011-05-03
申请人： Therese O'Day , Frank J. Fisher , Lindsay Koren , Mark Allen Magnuson , Richard Earl Luedemann , Shyam Kuppurathanam , Keith R. Milner
发明人： Therese O'Day , Frank J. Fisher , Lindsay Koren , Mark Allen Magnuson , Richard Earl Luedemann , Shyam Kuppurathanam , Keith R. Milner
IPC分类号： A61M25/00
CPC分类号： A61M25/007
摘要： A method of treating an intravascular site in a patient includes spraying jets of treatment fluid out of spray orifices formed in an elongate catheter body, and changing an impingement pattern of the treatment fluid on material within the intravascular site in response to a torque induced by a back pressure of the jets. A thrombolysis catheter includes an elongate catheter body having a plurality of spray orifices formed in a body wall, and communicating with a fluid lumen longitudinally extending in the elongate catheter body. The plurality of spray orifices define a torque inducing spray jet pattern, whereby a back pressure of spray jets exiting the spray orifices induces a torque on the elongate catheter body.
摘要翻译：一种治疗患者血管内部位的方法包括从形成于细长导管体内的喷孔喷射治疗液的喷射，并且响应于由所述血管内位置引起的扭矩，改变治疗流体在血管内部位内的材料的冲击模式喷气机的背压。溶栓导管包括细长导管主体，其具有形成在体壁中的多个喷孔，并且与在细长导管主体中纵向延伸的流体腔连通。多个喷射孔限定了转矩诱导喷射喷射图案，由此离开喷嘴的喷射射流的背压在细长导管主体上引起扭矩。

4. 发明申请

US20130046282A1 Method Of Treating An Intravascular Site In A Patient, And Thrombolysis Catheter Therefor 有权
标题翻译：治疗患者血管内位置的方法及其溶栓导管
公开(公告)号：US20130046282A1
公开(公告)日：2013-02-21
申请号：US13695915
申请日：2011-05-03
申请人： Therese O'Day , Frank J. Fisher , Lindsay Koren , Mark Allen Magnuson , Richard Earl Luedemann , Shyam Kuppurathanam , Keith R. Milner
发明人： Therese O'Day , Frank J. Fisher , Lindsay Koren , Mark Allen Magnuson , Richard Earl Luedemann , Shyam Kuppurathanam , Keith R. Milner
IPC分类号： A61M11/00 , A61M25/14
CPC分类号： A61M25/007
摘要： A method of treating an intravascular site in a patient includes spraying jets of treatment fluid out of spray orifices formed in an elongate catheter body, and changing an impingement pattern of the treatment fluid on material within the intravascular site in response to a torque induced by a back pressure of the jets. A thrombolysis catheter includes an elongate catheter body having a plurality of spray orifices formed in a body wall, and communicating with a fluid lumen longitudinally extending in the elongate catheter body. The plurality of spray orifices define a torque inducing spray jet pattern, whereby a back pressure of spray jets exiting the spray orifices induces a torque on the elongate catheter body.
摘要翻译：一种治疗患者血管内部位的方法包括从形成于细长导管体内的喷孔喷射治疗液的喷射，并且响应于由所述血管内位置引起的扭矩，改变治疗流体在血管内部位内的材料的冲击模式喷气机的背压。溶栓导管包括细长导管主体，其具有形成在体壁中的多个喷孔，并且与在细长导管主体中纵向延伸的流体腔连通。多个喷射孔限定了转矩诱导喷射喷射图案，由此离开喷嘴的喷射射流的背压在细长导管主体上引起扭矩。

5. 发明授权

US08568369B2 Infusion catheter and method 有权
标题翻译：输液导管及方法
公开(公告)号：US08568369B2
公开(公告)日：2013-10-29
申请号：US12851005
申请日：2010-08-05
申请人： Therese O'Day , Richard Earl Luedemann , Shyam Kuppurathanam
发明人： Therese O'Day , Richard Earl Luedemann , Shyam Kuppurathanam
IPC分类号： A61M25/00 , A61M5/00
CPC分类号： A61M25/0043 , A61M25/0075 , A61M2025/0057 , A61M2025/0079
摘要： An infusion catheter includes an elongate catheter body having a proximal body component and a distal body component. The distal body component includes a distal body outer surface and a distal body inner surface defining an infusion lumen. The distal body component further includes a skeleton, and a porous infusion control textile contacting the skeleton and extending circumferentially about a longitudinal axis of the catheter and defining a fluid emission profile thereof. The porous infusion control textile further includes a fiber network having a higher density space filling configuration at a proximal textile end and a lower density space filling configuration at a distal textile end, and defining a pressure sensitive flow rate property and a pressure insensitive flow distribution property of the fluid emission profile.
摘要翻译：输液导管包括具有近端主体部件和远端主体部件的细长导管主体。远侧主体部件包括远端本体外表面和限定出液腔的远侧主体内表面。所述远侧主体部件还包括骨架，以及多孔输注控制织物，其与所述骨架接触并围绕所述导管的纵向轴线周向延伸并且限定其流体发射轮廓。多孔输注控制织物还包括在近端纺织品端具有较高密度空间填充构型的纤维网络和在远端纺织品端处具有较低密度空间填充构型，并限定压力敏感流速性质和不敏感压力流动分布特性的流体排放曲线。

6. 发明申请

US20120035586A1 Infusion Catheter And Method 有权
标题翻译：输液管和方法
公开(公告)号：US20120035586A1
公开(公告)日：2012-02-09
申请号：US12851005
申请日：2010-08-05
申请人： Therese O'Day , Richard Earl Luedemann , Shyam Kuppurathanam
发明人： Therese O'Day , Richard Earl Luedemann , Shyam Kuppurathanam
IPC分类号： A61M25/00
CPC分类号： A61M25/0043 , A61M25/0075 , A61M2025/0057 , A61M2025/0079
摘要： An infusion catheter includes an elongate catheter body having a proximal body component and a distal body component. The distal body component includes a distal body outer surface and a distal body inner surface defining an infusion lumen. The distal body component further includes a skeleton, and a porous infusion control textile contacting the skeleton and extending circumferentially about a longitudinal axis of the catheter and defining a fluid emission profile thereof. The porous infusion control textile further includes a fiber network having a higher density space filling configuration at a proximal textile end and a lower density space filling configuration at a distal textile end, and defining a pressure sensitive flow rate property and a pressure insensitive flow distribution property of the fluid emission profile.
摘要翻译：输液导管包括具有近端主体部件和远侧主体部件的细长导管主体。远侧主体部件包括远端本体外表面和限定出液腔的远侧主体内表面。所述远侧主体部件还包括骨架，以及多孔输注控制织物，其与所述骨架接触并围绕所述导管的纵向轴线周向延伸并且限定其流体发射轮廓。多孔输注控制织物还包括在近端纺织品端具有较高密度空间填充构型的纤维网络和在远端纺织品端处具有较低密度空间填充构型，并限定压力敏感流速性质和不敏感压力流动分布特性的流体排放曲线。

7. 发明授权

US08574218B2 Catheter, fluid conveying method, and percutaneous procedure 有权
标题翻译：导管，液体输送法和经皮手术
公开(公告)号：US08574218B2
公开(公告)日：2013-11-05
申请号：US12776650
申请日：2010-05-10
申请人： Therese O'Day
发明人： Therese O'Day
IPC分类号： A61M25/00 , A61M1/00
CPC分类号： A61M25/0021 , A61M25/007 , A61M2025/0057 , A61M2025/006
摘要： A catheter includes an elongate catheter body having an outer surface with a non-uniform contour and including a plurality of maximum surface elevation points and a plurality of minimum surface elevation points defining a non-uniform elevation profile relative to a longitudinal axis of the catheter body. The outer surface further includes a fluid transfer interface which includes the plurality of minimum surface elevation points and a plurality of porous surface areas, and a tissue contact interface which includes the plurality of maximum surface elevation points and a plurality of nonporous surface areas. The tissue contact interface inhibits external occlusion of the fluid transfer interface during transferring fluid between a fluid lumen defined by the elongate catheter body, and an intraluminal space such as an intravascular space within a patient.
摘要翻译：导管包括细长的导管主体，其具有外表面具有不均匀的轮廓并且包括多个最大表面仰角点和多个最小表面仰角点，其限定相对于导管主体的纵向轴线的不均匀的仰角轮廓。外表面还包括流体传递界面，其包括多个最小表面仰角和多个多孔表面区域，以及包括多个最大表面高度点和多个无孔表面区域的组织接触界面。组织接触界面在由细长的导管主体限定的流体腔和腔内空间（例如患者内的血管内空间）之间传送流体期间抑制流体转移界面的外部阻塞。

8. 发明申请

US20110276022A1 Catheter, Fluid Conveying Method, And Percutaneous Procedure 有权
标题翻译：导管，流体输送方法和经皮程序
公开(公告)号：US20110276022A1
公开(公告)日：2011-11-10
申请号：US12776650
申请日：2010-05-10
申请人： Therese O'Day
发明人： Therese O'Day
IPC分类号： A61M25/00
CPC分类号： A61M25/0021 , A61M25/007 , A61M2025/0057 , A61M2025/006
摘要： A catheter includes an elongate catheter body having an outer surface with a non-uniform contour and including a plurality of maximum surface elevation points and a plurality of minimum surface elevation points defining a non-uniform elevation profile relative to a longitudinal axis of the catheter body. The outer surface further includes a fluid transfer interface which includes the plurality of minimum surface elevation points and a plurality of porous surface areas, and a tissue contact interface which includes the plurality of maximum surface elevation points and a plurality of nonporous surface areas. The tissue contact interface inhibits external occlusion of the fluid transfer interface during transferring fluid between a fluid lumen defined by the elongate catheter body, and an intraluminal space such as an intravascular space within a patient.
摘要翻译：导管包括细长的导管主体，其具有外表面具有不均匀的轮廓并且包括多个最大表面仰角点和多个最小表面仰角点，其限定相对于导管主体的纵向轴线的不均匀的仰角轮廓。外表面还包括流体传递界面，其包括多个最小表面仰角和多个多孔表面区域，以及包括多个最大表面高度点和多个无孔表面区域的组织接触界面。组织接触界面在由细长的导管主体限定的流体腔和腔内空间（例如患者内的血管内空间）之间传送流体期间抑制流体转移界面的外部阻塞。

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