专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明公开

EP4028058A1 COMPOSITIONS AND METHODS FOR MAKING AND USING MULTISPECIFIC ANTIBODIES 审中-实审
公开(公告)号：EP4028058A1
公开(公告)日：2022-07-20
申请号：EP20864086.2
申请日：2020-09-09
申请人： The Regents of the University of California , Liu, Bin , Lang, Shanshan , Su, Yang , Bidlingmaier, Scott , Lee, Nam-Kyung
发明人： LIU, Bin , LANG, Shanshan , SU, Yang , BIDLINGMAIER, Scott , LEE, Nam-Kyung
IPC分类号： A61K39/395 , C07K16/28 , C07K16/46 , C12N15/09

2. 发明申请

WO2021050527A1 COMPOSITIONS AND METHODS FOR MAKING AND USING MULTISPECIFIC ANTIBODIES 审中-公开
公开(公告)号：WO2021050527A1
公开(公告)日：2021-03-18
申请号：PCT/US2020/049914
申请日：2020-09-09
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA , LIU, Bin , LANG, Shanshan , SU, Yang , BIDLINGMAIER, Scott , LEE, Nam-Kyung
发明人： LIU, Bin , LANG, Shanshan , SU, Yang , BIDLINGMAIER, Scott , LEE, Nam-Kyung
IPC分类号： A61K39/395 , C07K16/28 , C07K16/46 , C12N15/09
摘要： The present disclosure relates generally to compositions and methods useful for the production of engineered antibodies having (i) multiple antigen-binding specificities and (ii) Fc regions that have been modified to promote heterodimer formation between heavy chains from antibodies with different specificities. Also provided are recombinant cells, recombinant nucleic acids encoding such engineered antibodies, as well as pharmaceutical compositions containing same.

3. 发明申请

WO2023044498A2 NOVEL WNT AGONIST ANTIBODIES AND THERAPEUTIC USES THEREOF 审中-公开
公开(公告)号：WO2023044498A2
公开(公告)日：2023-03-23
申请号：PCT/US2022/076706
申请日：2022-09-20
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
发明人： LIU, Bin , LEE, Nam-Kyung , BIDLINGMAIER, Scott , SU, Yang
IPC分类号： A61K39/395 , C07K16/28
摘要： Antibodies are provided herein that agonize Wnt signaling, do not compete with a Wnt ligand for LRP6 binding, and activate Wnt signaling in the presence of inhibitors. Methods for promoting cell differentiation and tissue regeneration using the disclosed antibodies are also provided.

4. 发明公开

EP4405394A2 NOVEL WNT AGONIST ANTIBODIES AND THERAPEUTIC USES THEREOF 审中-公开
公开(公告)号：EP4405394A2
公开(公告)日：2024-07-31
申请号：EP22871024.0
申请日：2022-09-20
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
发明人： LIU, Bin , LEE, Nam-Kyung , BIDLINGMAIER, Scott , SU, Yang
IPC分类号： C07K16/28 , A61K39/395 , A61P27/02
CPC分类号： C07K16/22 , C07K2317/7520130101 , C07K2317/62220130101 , C07K2317/3420130101 , C07K2317/9220130101 , C07K2317/7020130101 , A61P19/08 , A61K2039/50520130101

5. 发明申请

WO2018094282A1 ENGINEERED ANTIBODIES AND USES THEREOF 审中-公开
公开(公告)号：WO2018094282A1
公开(公告)日：2018-05-24
申请号：PCT/US2017/062418
申请日：2017-11-17
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
发明人： LIU, Bin , LEE, Nam-Kyung , SU, Yang , BIDLINGMAIER, Scott
IPC分类号： A61K39/395 , A61K31/713 , C07K16/28 , C07K16/30 , G01N33/53 , G01N33/574 , C07H21/04
摘要： The present disclosure relates to an engineered antibody that co-engages a cell type- selective (or specific) antigen (guide) and a signaling receptor (effector) on a target cell. In some instances, the engineered antibody is capable of modulating a signaling pathway on a target cell. In other embodiments, an engineered antibody of the present disclosure is administered to a subject for the treatment of a disease or condition.

6. 发明申请

WO2010008154A2 ROOM TEMPERATURE MOISTURE CURABLE HYBRID RESIN, METHOD OF PREPARING THE SAME AND APPLICATION THEREOF 审中-公开
标题翻译：室温湿度可固化混合树脂，其制备方法及其应用
公开(公告)号：WO2010008154A2
公开(公告)日：2010-01-21
申请号：PCT/KR2009/003754
申请日：2009-07-09
申请人： KOREA BIO-GEN CO., LTD , BOO, Tai-woong , KIM, Chun-Mi , LIM, Yeun-Su , LEE, Nam-Kyung
发明人： BOO, Tai-woong , KIM, Chun-Mi , LIM, Yeun-Su , LEE, Nam-Kyung
IPC分类号： C08G18/83 , C08G18/82 , C08G18/61 , C08G18/00
CPC分类号： C08G18/12 , C08G18/4804 , C08G18/4866 , C08G18/718 , C08G2190/00 , C08G18/289
摘要： Disclosed are a room temperature moisture-curable hybrid resin, a method of preparing the same and application thereof. More particularly, disclosed are a room temperature moisture- curable hybrid resin obtained by reacting a hydroxyl-terminated prepolymer or a polyether polyol having a weight average molecular weight of 8,000-60,000 with an isocyanatoalkylsilane compound, a room temperature moisture-curable hybrid resin obtained by reacting an isocyanate-terminated prepolymer with a sec-aminosilane compound, and methods of preparing the same. The room temperature moisture-curable hybrid resin has easily controllable viscosity to provide good workability, provides a polymer resin having a wide range of modulus and elongation characteristics derived therefrom, and may be provided with a wide spectrum of me¬ chanical and physical properties including increased elasticity of a cured resin. Therefore, the room temperature moisture-curable hybrid resin may be applied to sealants, adhesives, binders, coating agents, etc. for use in various industrial fields including construction, electric/electronic and automobile industries.
摘要翻译：公开了室温可湿固化的杂化树脂，其制备方法和应用。更具体地，公开了通过使羟基封端的预聚物或重均分子量为8,000-60,000的聚醚多元醇与异氰酸根合烷基硅烷化合物反应获得的室温可湿固化的杂化树脂，室温可湿固化的杂化树脂使异氰酸酯封端的预聚物与仲氨基硅烷化合物反应，及其制备方法。室温可湿固化的杂化树脂具有易于控制的粘度以提供良好的可加工性，提供了由其衍生的具有宽范围的模量和伸长特性的聚合物树脂，并且可以提供广谱的机械和物理性能，包括增加固化树脂的弹性。因此，可以将室温可湿固化的混合树脂应用于在建筑，电气/电子和汽车工业等各种工业领域中使用的密封剂，粘合剂，粘合剂，涂布剂等。

7. 发明申请

WO2009151187A1 METHOD AND APPARATUS FOR ROUTING IN WIRELESS NETWORK 审中-公开
标题翻译：在无线网络中路由的方法和装置
公开(公告)号：WO2009151187A1
公开(公告)日：2009-12-17
申请号：PCT/KR2008/006506
申请日：2008-11-05
申请人： ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE , LEE, Nam-Kyung , CHANG, Dae-Ig , LEE, Ho-Jin , LEE, Dong-Jun
发明人： LEE, Nam-Kyung , CHANG, Dae-Ig , LEE, Ho-Jin , LEE, Dong-Jun
IPC分类号： H04L12/28
CPC分类号： H04W40/28 , H04L45/123 , H04L45/125
摘要： A method of routing a wireless network is provided. The method is performed by each of a group of nodes and includes: receiving a routing request signal; determining whether a node itself is a destination node, by referring to a traffic distribution table showing traffic throughput of the group of nodes and an intermediate-node weight table showing weights of intermediate nodes on all paths between the group of nodes and a source node, wherein a route path is selected by referring to the weights of intermediate nodes; and when it is determined that the node itself is the destination node transmitting a routing response signal to the source node that has transmitted the routing request signal, and receiving a packet from the source node, wherein the transmitting and receiving are performed by the determined destination node. By using the method, traffic in wireless network extreme communications can be distributed at intermediate nodes as well as at destination nodes. Therefore, all the networks can be effectively used in extreme circumstances.
摘要翻译：提供了一种路由无线网络的方法。该方法由一组节点中的每一个执行，并且包括：接收路由请求信号; 通过参考示出节点组的流量的流量分布表和表示节点组和源节点之间的所有路径上的中间节点的权重的中间节点权重表来确定节点本身是否是目的地节点，其中通过参考中间节点的权重来选择路由路径; 并且当确定节点本身是目的地节点向已经发送了路由请求信号的源节点发送路由响应信号，并且从源节点接收分组时，由确定的目的地执行发送和接收节点。通过使用该方法，可以在中间节点以及目的地节点处分配无线网络极端通信中的业务。因此，所有网络都可以在极端情况下有效使用。

8. 发明申请

WO2009078526A1 HANDOVER METHOD FOR MOBILE WIRELESS NETWORK 审中-公开
标题翻译：移动无线网络的切换方法
公开(公告)号：WO2009078526A1
公开(公告)日：2009-06-25
申请号：PCT/KR2008/004069
申请日：2008-07-10
申请人： ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE , UNIVERSITY-INDUSTRY COOPERATION FOUNDATION KOREA AEROSPACE UNIVERSITY , LEE, Nam-Kyung , LEE, Dong-Jun , HAN, Myunghee , KIM, Hokyom
发明人： LEE, Nam-Kyung , LEE, Dong-Jun , HAN, Myunghee , KIM, Hokyom
IPC分类号： H04B7/26 , H04L12/28
CPC分类号： H04W8/06 , H04W36/0011 , H04W40/36 , H04W80/04 , H04W84/06
摘要： Provided is a handover method for a mobile wireless network. The handover method for a mobile wireless network, including: receiving, by a mobile node, information on a new access router by requesting the information necessary for the handover from a previous access router in accordance with a handover initiation; sending a fast binding update message to the previous access router via the new access router by connecting to the new access router; receiving a packet from the new access router; and disconnecting from the previous access router.
摘要翻译：提供了一种用于移动无线网络的切换方法。一种用于移动无线网络的切换方法，包括：由移动节点通过根据切换启动请求从先前访问路由器进行的切换所需的信息来接收关于新接入路由器的信息; 通过连接到新的接入路由器，经由新的接入路由器向先前接入路由器发送快速绑定更新消息; 从新的接入路由器接收分组; 并断开与之前的接入路由器的连接。

9. 发明申请

WO2007064116A1 APPARATUS AND METHOD FOR RECOMBINING MULTI-PROTOCOL ENCAPSULATION (MPE) PACKETS 审中-公开
标题翻译：用于重新构建多协议包（MPE）包的装置和方法
公开(公告)号：WO2007064116A1
公开(公告)日：2007-06-07
申请号：PCT/KR2006/005020
申请日：2006-11-27
申请人： ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE , KIM, Won-Ho , LEE, Nam-Kyung , SONG, Yun-Jeong
发明人： KIM, Won-Ho , LEE, Nam-Kyung , SONG, Yun-Jeong
IPC分类号： H04B7/195 , H04N7/12 , H04N7/24
CPC分类号： H04N21/6143 , H04L69/08 , H04N21/2381 , H04N21/4381 , H04N21/6193 , H04N21/64307
摘要： Provided is an apparatus and method for recombining multi-protocol encapsulation (MPE) packets. The apparatus includes the steps of: a buffer for buffering transport stream (TS) packets; a first memory for temporally storing residue data; a second memory for storing a residue data existence flag and length information of data; a MPE recombination processor for analyzing header information, storing the length information of an MPE packet, creating an asynchronous transfer mode (ATM) cell header, reading packet data, creating and outputting an ATM adaptive layer 0 (AALO-ATM) cell and the read packet data, updating the length information of the data, reading the residue data, reading insufficient data and creating an AALO-ATM cell; and a segmentation and reassemble (SAR) processor for buffering the AALO-ATM cell, and transporting the AALO-ATM cell.
摘要翻译：提供了一种用于重组多协议封装（MPE）分组的装置和方法。该装置包括以下步骤：缓冲传输流（TS）分组的缓冲器; 用于暂时存储残留数据的第一存储器; 用于存储残差数据存在标志和数据的长度信息的第二存储器; 用于分析报头信息的MPE重组处理器，存储MPE分组的长度信息，创建异步传输模式（ATM）信元报头，读取分组数据，创建并输出ATM自适应层0（AALO-ATM）单元和所读取的分组数据，更新数据的长度信息，读取残差数据，读取不足的数据和创建AALO-ATM信元; 以及用于缓冲AALO-ATM信元的分组和重组（SAR）处理器，以及传输AALO-ATM信元。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式