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1. 发明授权

US09381055B2 Therapeutic cryoablation system 有权
公开(公告)号：US09381055B2
公开(公告)日：2016-07-05
申请号：US13942387
申请日：2013-07-15
申请人： Thach Duong , Min Frank Zeng , Peng Liu , Chaohua Xin
发明人： Thach Duong , Min Frank Zeng , Peng Liu , Chaohua Xin
IPC分类号： A61B18/02 , A61B18/00
CPC分类号： A61B18/02 , A61B2017/00323 , A61B2018/00101 , A61B2018/0022 , A61B2018/00285 , A61B2018/00577 , A61B2018/0212 , A61B2018/0287
摘要： A cryoablation system has a gas source which provides a working nitrogen gas at room temperature and at a constant set pressure, a liquid generator which is coupled to the gas source to receive the working gas, and which then generates a working cryogen fluid, and a catheter coupled to the liquid generator for receiving the working cryogen, the catheter having a distal section having a freezing element which delivers the working cryogen to a treatment location, the catheter also having a balloon positioned adjacent the distal section.

2. 发明授权

US09072500B2 Therapeutic cryoablation system 有权
标题翻译：治疗性冷冻消融系统
公开(公告)号：US09072500B2
公开(公告)日：2015-07-07
申请号：US13800402
申请日：2013-03-13
申请人： Thach Duong , Min Frank Zeng
发明人： Thach Duong , Min Frank Zeng
IPC分类号： A61B18/18 , A61B18/02 , A61B18/00
CPC分类号： A61B18/02 , A61B2018/0022 , A61B2018/0212 , A61B2018/0268
摘要： A cryoablation system has a gas source which provides a working nitrogen gas at room temperature and at a constant set pressure, a liquid generator which is coupled to the gas source to receive the working gas, and which then generates a working cryogen fluid, and a catheter coupled to the liquid generator for receiving the working cryogen, the catheter having a distal section having a freezing element which delivers the working cryogen to a treatment location, the catheter also having a balloon positioned adjacent the distal section.
摘要翻译：冷冻消融系统具有在室温和恒定的设定压力下提供工作氮气的气体源，液体发生器，其耦合到气体源以接收工作气体，然后产生工作中的制冷剂流体，导管联接到液体发生器以接收工作制冷剂，导管具有远端部分，该远端部分具有将工作制冷剂输送到处理位置的冷冻元件，该导管还具有邻近远端部分定位的球囊。

3. 发明授权

US08747396B2 Cryosurgical probe with adjustable sliding apparatus 有权
标题翻译：具有可调式滑动装置的冷冻手术探头
公开(公告)号：US08747396B2
公开(公告)日：2014-06-10
申请号：US12581145
申请日：2009-10-18
申请人： Thach Duong , Jay J. Eum
发明人： Thach Duong , Jay J. Eum
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B2017/00274 , A61B2017/0046 , A61B2018/00547 , A61B2018/0262 , A61B2090/3925
摘要： A cryosurgical probe assembly that includes a gas delivery assembly, including a stem and a fluid conduit subassembly bonded to the stem. The fluid conduit subassembly delivers and returns cooling fluid used for cryogenic cooling. The fluid conduit subassembly, comprises a shaft for providing a heat exchange surface for cryogenic ablation; a housing securely connected to said shaft; and, an insulation element slideably engaged with an inner surface of the shaft and slideably engaged with the stem. The cryosurgical probe assembly includes an adjustable sliding apparatus that includes a slider assembly securely attached to said insulation tube for slideably guiding the insulation tube along said shaft; and, a button assembly operatively connected to the slider assembly for allowing a user to actuate the slider assembly to provide a desired adjustment of the insulation tube relative to the shaft. A handle assembly is positioned about the housing.
摘要翻译：一种冷冻手术探针组件，其包括气体输送组件，其包括杆和结合到所述杆的流体导管子组件。流体导管子组件输送并返回用于低温冷却的冷却流体。流体导管子组件包括用于提供用于低温消融的热交换表面的轴; 牢固地连接到所述轴的壳体; 以及绝缘元件，其与所述轴的内表面可滑动地接合并且可滑动地与所述杆接合。冷冻手术探针组件包括一个可调节的滑动装置，其包括牢固地附接到所述绝缘管的滑动器组件，用于沿着所述轴可滑动地引导绝缘管; 以及可操作地连接到滑块组件的按钮组件，用于允许使用者致动滑块组件以提供相对于轴的绝缘管的期望调节。手柄组件围绕壳体定位。

4. 发明申请

US20080147055A1 Cryosurgical Probe With Vacuum Insulation Tube Assembly 有权
标题翻译：带真空绝热管组件的冷冻外科探头
公开(公告)号：US20080147055A1
公开(公告)日：2008-06-19
申请号：US11613054
申请日：2006-12-19
申请人： Thach Duong , Jenny C. Liu , Jay J. Eum
发明人： Thach Duong , Jenny C. Liu , Jay J. Eum
IPC分类号： A61B18/18 , F16L9/18 , B23K15/06 , B23Q3/00
CPC分类号： A61B18/02 , A61B2018/0262 , F16L9/18 , F16L59/065 , F16L59/14
摘要： A vacuum insulation tube assembly which is utilized as a component in a cryosurgical probe. The vacuum insulation tube assembly includes an inner tube; and, an outer tube concentrically positioned about the inner tube. The outer tube is securely soldered at end portions of the inner tube and forms a vacuum space between the inner tube and the outer tube. The vacuum tube assemblies may be conveniently mass produced using a special fixture.
摘要翻译：一种真空绝热管组件，用作冷冻手术探头中的组件。真空绝热管组件包括内管; 以及围绕内管同心定位的外管。外管在内管的端部牢固地焊接，并在内管和外管之间形成真空空间。真空管组件可以使用特殊的夹具方便地批量生产。

5. 发明授权

US07189228B2 Detachable cryosurgical probe with breakaway handle 有权
标题翻译：具有分离手柄的可拆卸冷冻手术探头
公开(公告)号：US07189228B2
公开(公告)日：2007-03-13
申请号：US11116873
申请日：2005-04-28
申请人： Jay J. Eum , Thach Duong , Paul LaPine
发明人： Jay J. Eum , Thach Duong , Paul LaPine
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B2017/0046 , A61B2018/0262
摘要： The detachable cryosurgical probe includes a disposable probe assembly and a reusable probe assembly. The disposable probe assembly includes a breakaway collar which, when twisted away, activates a finger lock element which provides release of the disposable probe assembly from the reusable probe assembly. Additional features include a safety valve assembly for impeding cryogenic working fluid flow when the disposable probe assembly is detached from the reusable probe assembly and an electrical confirmation assembly for providing electrical confirmation that the disposable probe assembly is connected. Other embodiments include a sliding mechanism that allows for selectively positioning of the vacuum tube relative to the shaft to create an ice ball of the desired size and configuration.
摘要翻译：可拆卸的冷冻手术探针包括一次性探针组件和可重复使用的探针组件。一次性探针组件包括分离套环，当被扭转时，该开口套环激活手指锁定元件，其提供一次性探针组件从可重复使用的探针组件的释放。另外的特征包括一个安全阀组件，用于当一次性探头组件与可重复使用的探头组件分离时阻止低温工作流体流动;以及电气确认组件，用于提供一次性探头组件连接的电气确认。其它实施例包括允许真空管相对于轴选择性定位以产生所需尺寸和构造的冰球的滑动机构。

6. 发明申请

US20050043725A1 Threaded cryostat for cryosurgical probe system 有权
标题翻译：螺纹低温恒温器用于冷冻探头系统
公开(公告)号：US20050043725A1
公开(公告)日：2005-02-24
申请号：US10954433
申请日：2004-09-30
申请人： Thach Duong , James Dinh
发明人： Thach Duong , James Dinh
IPC分类号： A61B17/00 , A61B18/02 , F25B9/02 , F28D7/10
CPC分类号： F25B9/02 , A61B18/02 , A61B2017/0046 , A61B2018/00041 , A61B2018/0262 , A61B2018/0293 , F28D7/106 , F28F2255/18
摘要： The threaded cryostat for a cryosurgical probe system includes an outer tube and a hollow elongated threaded element positioned within the outer tube. The threaded element has integral, external threads that extend from on an outer surface thereof. During operation a working fluid is transported in a first direction between a fluid supply line and a distal end of a cryosurgical probe within a first space defined within the threaded element. Working fluid is transported in a second direction between the distal end of the cryosurgical probe and the fluid supply line within a second space defined between the outer tube and the threaded element.
摘要翻译：用于冷冻手术探针系统的螺纹低温恒温器包括外管和位于外管内的中空细长螺纹元件。螺纹元件具有从其外表面延伸的整体的外螺纹。在操作期间，工作流体在限定在螺纹元件内的第一空间内的流体供应管线和冷冻手术探针的远端之间沿第一方向输送。在外管和螺纹元件之间限定的第二空间内，工作流体沿第二方向输送在冷冻外科探针的远端和流体供应管线之间。

7. 发明授权

US07608071B2 Cryosurgical probe with adjustable sliding apparatus 有权
标题翻译：具有可调式滑动装置的冷冻手术探头
公开(公告)号：US07608071B2
公开(公告)日：2009-10-27
申请号：US11857095
申请日：2007-09-18
申请人： Thach Duong , Jay J. Eum
发明人： Thach Duong , Jay J. Eum
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B2017/00274 , A61B2017/0046 , A61B2018/00547 , A61B2018/0262 , A61B2090/3925
摘要： A cryosurgical probe assembly that includes a gas delivery assembly, including a stem and a fluid conduit subassembly bonded to the stem. The fluid conduit subassembly delivers and returns cooling fluid used for cryogenic cooling. The fluid conduit subassembly, comprises a shaft for providing a heat exchange surface for cryogenic ablation; a housing securely connected to said shaft; and, an insulation element slideably engaged with an inner surface of the shaft and slideably engaged with the stem. The cryosurgical probe assembly includes an adjustable sliding apparatus that includes a slider assembly securely attached to said insulation tube for slideably guiding the insulation tube along said shaft; and, a button assembly operatively connected to the slider assembly for allowing a user to actuate the slider assembly to provide a desired adjustment of the insulation tube relative to the shaft. A handle assembly is positioned about the housing.
摘要翻译：一种冷冻手术探针组件，其包括气体输送组件，其包括杆和结合到所述杆的流体导管子组件。流体导管子组件输送并返回用于低温冷却的冷却流体。流体导管子组件包括用于提供用于低温消融的热交换表面的轴; 牢固地连接到所述轴的壳体; 以及绝缘元件，其与所述轴的内表面可滑动地接合并且可滑动地与所述杆接合。冷冻手术探针组件包括一个可调节的滑动装置，其包括牢固地附接到所述绝缘管的滑动器组件，用于沿着所述轴可滑动地引导绝缘管; 以及可操作地连接到滑块组件的按钮组件，用于允许使用者致动滑块组件以提供相对于轴的绝缘管的期望调节。手柄组件围绕壳体定位。

8. 发明授权

US07160291B2 Detachable cryosurgical probe 有权
标题翻译：可拆卸式冷冻手术探针
公开(公告)号：US07160291B2
公开(公告)日：2007-01-09
申请号：US10828031
申请日：2004-04-20
申请人： Sanford D. Damasco , Thach Duong
发明人： Sanford D. Damasco , Thach Duong
IPC分类号： A61B18/02
CPC分类号： F25B9/02 , A61B18/02 , A61B2017/0046 , A61B2018/00041 , A61B2018/0262 , A61B2018/0293 , F28D7/106 , F28F2255/18
摘要： A cryosurgical probe system includes a fluid supply line connectable at an inlet section to a source of cryogenic fluid; a fluid connector assembly securely connected to an outlet section of the fluid supply line for receiving fluid from the outlet section of the fluid supply line; and, a detachable cryosurgical probe detachably connectable to the fluid connector assembly. The cryosurgical probe system includes the capability of providing return fluid flow.
摘要翻译：冷冻手术探针系统包括可在入口部分连接到低温流体源的流体供应管线; 流体连接器组件，其牢固地连接到流体供应管线的出口部分，用于从流体供应管线的出口部分接收流体; 以及可拆卸地连接到流体连接器组件的可拆卸冷冻手术探针。冷冻手术探针系统包括提供回流流体的能力。

9. 发明申请

US20060264920A1 Cryosurgical probe assembly with multiple deployable cryoprobes 有权
标题翻译：具有多个可部署冷冻探头的冷冻探头组件
公开(公告)号：US20060264920A1
公开(公告)日：2006-11-23
申请号：US11430323
申请日：2006-05-09
申请人： Thach Duong
发明人： Thach Duong
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B2018/0262 , A61B2018/0293
摘要： The cryosurgical probe assembly with multiple deployable cryoprobes includes a) a housing assembly; b) a plurality of elongated structural support elements, each securely connected at a first end to the housing assembly; c) a tip member securely connected to second ends of the plurality of elongated structural support elements, the tip member including a plurality of cryoprobe openings; and, d) a plurality of cryoprobes each having a shaft thereon, each shaft being deployable through a respective cryoprobe opening during operation to a deployed position used for ablating tissue. In an alternate embodiment, a cylindrical housing is utilized rather than elongated structural support elements.
摘要翻译：具有多个可展开冷冻探针的冷冻手术探针组件包括：a）壳体组件; b）多个细长结构支撑元件，每个细长结构支撑元件在第一端处牢固地连接到壳体组件; c）尖端构件，其牢固地连接到所述多个细长结构支撑元件的第二端，所述尖端构件包括多个冷冻探针开口; 以及d）多个各自具有轴的冷冻探针，每个轴可在操作期间通过相应的冷冻探针开口展开到用于烧蚀组织的展开位置。在替代实施例中，使用圆柱形壳体而不是细长的结构支撑元件。

10. 发明申请

US20060015093A1 Open system heat exchange catheters and methods of use 审中-公开
标题翻译：开放系统热交换导管及使用方法
公开(公告)号：US20060015093A1
公开(公告)日：2006-01-19
申请号：US11231263
申请日：2005-09-20
申请人： Jay Eum , Thach Duong
发明人： Jay Eum , Thach Duong
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B2018/00041 , A61B2018/046
摘要： Various embodiments of open system heat exchange catheters and methods of use are disclosed. The various catheters can be used with various ablative surgical devices. One specific exemplary use is in conjunction with cryosurgical probes involving ablation of the prostate, in which the integrity of the urethra is desired to be maintained. Other uses involve various heating ablative devices. In one embodiment an injection tube assembly is used to provide heat exchange fluid through the urethra to the bladder where it is then expelled via a suprapubic suction tube. In other embodiments a coaxial tube assembly is utilized which defines a passageway for either expelling the bladder fluid or for providing access to an endoscope. In other embodiments a double lumen assembly is utilized that defines a passageway for expelling bladder fluid.
摘要翻译：公开了开放系统热交换导管和使用方法的各种实施例。各种导管可以与各种烧蚀手术装置一起使用。一个具体的示例性用途是结合涉及前列腺消融的冷冻手术探针，其中期望保持尿道的完整性。其他用途涉及各种加热烧蚀装置。在一个实施例中，注射管组件用于将热交换流体通过尿道提供给膀胱，然后通过耻骨上吸管将其排出。在其它实施例中，使用同轴管组件，其限定用于排出膀胱流体或用于提供对内窥镜的通路的通道。在其他实施例中，利用限定用于排出膀胱流体的通道的双腔组件。

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