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1. 发明授权

US5462550A Alignment guide and method 失效
标题翻译：校准指导和方法
公开(公告)号：US5462550A
公开(公告)日：1995-10-31
申请号：US143910
申请日：1993-10-27
申请人： Terry L. Dietz , Stephen C. Miller
发明人： Terry L. Dietz , Stephen C. Miller
IPC分类号： A61B17/90 , A61F2/38 , A61F2/46 , A61F5/00 , A61B17/58
CPC分类号： A61F2/461 , A61F2/3859 , A61F2002/4624 , A61F2002/4687
摘要： An alignment guide comprises a guide block locator having surfaces for engaging a prepared femur and establishing a specific position relative to an intercondylar slot in the femur. The guide block locator contains an aperture for directing a guide block to the specific position. The guide block includes a leg that can be driven into the femur to hold the guide block in place. The guide block is adapted to precisely engage the cam box of a femoral implant. Upon removal of the guide block locator, the femoral implant can be positioned over the guide block where the cam box will engage the guide block before the anterior and posterior flanges of the implant grip the anterior and posterior surfaces of the femur thereby providing proper alignment of the femur and implant.
摘要翻译：对准引导件包括具有用于接合准备的股骨的表面并且相对于股骨中的髁间隙建立特定位置的引导块定位器。引导块定位器包含用于将引导块引导到特定位置的孔。引导块包括可以被驱动到股骨中以将引导块保持在适当位置的腿部。引导块适于精确地接合股骨植入物的凸轮盒。在移除引导块定位器之后，股骨植入物可以定位在引导块上方，在该植入物的前部和后部法兰夹持股骨的前表面和后表面之前，凸轮盒将与引导块接合，从而提供正确对准股骨和植入物。

2. 发明授权

US08153393B2 Spirolactam targeting compounds and related compounds 有权
标题翻译：目标化合物和相关化合物
公开(公告)号：US08153393B2
公开(公告)日：2012-04-10
申请号：US12040839
申请日：2008-02-29
申请人： Stephen C. Miller , Anjan K. Bhunia
发明人： Stephen C. Miller , Anjan K. Bhunia
IPC分类号： C12Q1/02 , C07D265/38 , C07D487/00 , C07D311/78
CPC分类号： C07D491/10 , C07F9/80
摘要： Spirolactam targeting compounds, related compounds, uses of such compounds, and methods of making such compounds are disclosed.
摘要翻译：披露目标化合物，相关化合物，这些化合物的用途，以及制备这些化合物的方法。

3. 发明授权

US08083721B2 Power injection valve 有权
标题翻译：动力注射阀
公开(公告)号：US08083721B2
公开(公告)日：2011-12-27
申请号：US12362004
申请日：2009-01-29
申请人： Stephen C. Miller
发明人： Stephen C. Miller
IPC分类号： A61M5/178 , A61M5/00 , A61M3/00
CPC分类号： A61M39/22 , A61M39/24 , A61M2039/027 , A61M2039/242
摘要： A device for transferring fluids between an internal structure in a living body and an exterior thereof, comprises a housing including a pressure activated lumen extending to a distal end opening to a power injection lumen that extends to a distal port configured for connection to a fluid conduit extending to a target structure within the body and a pressure activated valve extending across the pressure activated lumen and controlling fluid flow therethrough, the pressure activated valve opening to permit fluid flow therethrough into the power injection lumen when a fluid pressure differential thereacross is at least a first predetermined threshold level and remaining sealed when the fluid pressure differential thereacross is less than the first threshold level in combination with a proximal port coupled to the housing for movement between a first position in which a proximal end of the power injection lumen opens to the proximal port and a second position in which a proximal end of the pressure activated lumen opens to the proximal port.
摘要翻译：用于在活体内部结构和其外部之间传送流体的装置包括壳体，该壳体包括延伸到动力注射腔的远端开口的压力活化腔，其延伸到被配置为连接到流体导管延伸到主体内的目标结构，以及压力激活的阀，其延伸穿过压力激活的腔并且控制流过其中的流体流动，所述压力启动的阀开口，以允许流体流过动力注射腔，当其中的流体压力差异至少为第一预定阈值水平，并且当所述流体压力差异超过所述第一阈值水平时，与耦合到所述壳体的近端口相结合地保持密封，以在第一位置和第二位置之间移动，其中所述动力注射腔的近端与所述近端端口和第二位置，其中近端 e压力活化腔通向近端口。

4. 发明申请

US20100191185A1 Power Injection Valve 有权
标题翻译：动力注射阀
公开(公告)号：US20100191185A1
公开(公告)日：2010-07-29
申请号：US12362004
申请日：2009-01-29
申请人： Stephen C. Miller
发明人： Stephen C. Miller
IPC分类号： A61M1/00
CPC分类号： A61M39/22 , A61M39/24 , A61M2039/027 , A61M2039/242
摘要： A device for transferring fluids between an internal structure in a living body and an exterior thereof, comprises a housing including a pressure activated lumen extending to a distal end opening to a power injection lumen that extends to a distal port configured for connection to a fluid conduit extending to a target structure within the body and a pressure activated valve extending across the pressure activated lumen and controlling fluid flow therethrough, the pressure activated valve opening to permit fluid flow therethrough into the power injection lumen when a fluid pressure differential thereacross is at least a first predetermined threshold level and remaining sealed when the fluid pressure differential thereacross is less than the first threshold level in combination with a proximal port coupled to the housing for movement between a first position in which a proximal end of the power injection lumen opens to the proximal port and a second position in which a proximal end of the pressure activated lumen opens to the proximal port.
摘要翻译：用于在活体内部结构和其外部之间传送流体的装置包括壳体，该壳体包括延伸到动力注射腔的远端开口的压力活化腔，其延伸至构造成连接到流体导管延伸到主体内的目标结构，以及压力激活的阀，其延伸穿过压力激活的腔并且控制流过其中的流体流动，所述压力启动的阀开口，以允许流体流过动力注射腔，当其中的流体压力差异至少为第一预定阈值水平，并且当所述流体压力差异超过所述第一阈值水平时，与耦合到所述壳体的近端口相结合地保持密封，以在第一位置和第二位置之间移动，其中所述动力注射腔的近端与所述近端端口和第二位置，其中近端 e压力活化腔通向近端口。

5. 发明授权

US4623601A Photoconductive device containing zinc oxide transparent conductive layer 失效
标题翻译：含有氧化锌透明导电层的光导体
公开(公告)号：US4623601A
公开(公告)日：1986-11-18
申请号：US740945
申请日：1985-06-04
申请人： Steven C. Lewis , Robert B. Love , Stephen C. Miller , Yuh-han Shing , John W. Sibert , David P. Tanner , Nang T. Tran
发明人： Steven C. Lewis , Robert B. Love , Stephen C. Miller , Yuh-han Shing , John W. Sibert , David P. Tanner , Nang T. Tran
IPC分类号： H01L31/0248 , H01L27/146 , H01L31/0224 , H01L31/04 , H01L31/075 , H01L31/10 , H01L31/18 , H01L31/20 , G03G5/082
CPC分类号： H01L31/075 , H01L31/022466 , H01L31/1884 , H01L31/202 , Y02E10/548 , Y02P70/521
摘要： A photoconductive device of decreased resistivity is provided by using at least one zinc oxide transparent conductive layer in conjunction with a thin film amorphous silicon photoconductor. The zinc oxide layer can be used as the front contact, the back contact or both the front and back contacts of the photoconductive device.
摘要翻译：通过使用与薄膜非晶硅光电导体结合的至少一个氧化锌透明导电层来提供电阻率降低的光电导器件。氧化锌层可用作光电导装置的前触点，后触点或前触点和后触点。

6. 发明公开

US20240257990A1 LEAD APRON SUSPENSION SYSTEM AND METHOD 审中-公开
公开(公告)号：US20240257990A1
公开(公告)日：2024-08-01
申请号：US18379391
申请日：2023-10-12
申请人： Stephen C. Miller
发明人： Stephen C. Miller
IPC分类号： G21F3/03 , A61B6/10
CPC分类号： G21F3/03 , A61B6/107
摘要： An apparatus suspends a personal radiation protection garment above a work surface. The suspension apparatus comprises a support member positioned above the work surface, a cable mechanically suspended from the support member, and means for counter-balancing the weight of the personal radiation protection garment attached to the cable. Means for attaching the counter-balancing means to the personal radiation protection garment suspend the personal radiation protection garment. The attaching means includes means for disconnecting the garment from the counter-balancing means, the disconnecting means manually operable by one hand of a user and disposed within reach of the user while wearing the personal radiation protection garment attached to the counter-balancing means. The personal radiation protection garment is supported in suspension and may be disconnected from the counter-balancing means by the one hand of the user for releasing the personal radiation protection garment from suspension while still being worn by the user.

7. 发明申请

US20140201855A1 MUTANT LUCIFERASES 有权
公开(公告)号：US20140201855A1
公开(公告)日：2014-07-17
申请号：US13984506
申请日：2012-02-09
申请人： Stephen C. Miller , David Mofford , Katryn Harwood
发明人： Stephen C. Miller , David Mofford , Katryn Harwood
IPC分类号： C12Q1/66 , C12N9/02
CPC分类号： C12Q1/66 , A01K2267/0393 , C07K2319/00 , C07K2319/02 , C07K2319/23 , C07K2319/30 , C07K2319/31 , C07K2319/50 , C12N9/0069 , C12Y113/12007
摘要： Described are mutant luciferases, nucleic acids that encode them, cells and animals expressing them, methods of use thereof, and kits.
摘要翻译：描述了突变荧光素酶，编码它们的核酸，表达它们的细胞和动物，其使用方法和试剂盒。

8. 发明授权

US08007468B2 Method to secure an elastic component in a valve 有权
标题翻译：将弹性部件固定在阀门中的方法
公开(公告)号：US08007468B2
公开(公告)日：2011-08-30
申请号：US12501809
申请日：2009-07-13
申请人： Stephen C. Miller
发明人： Stephen C. Miller
IPC分类号： A61M1/00
CPC分类号： A61M39/24 , A61M1/3653 , A61M1/3659 , A61M39/22 , A61M2039/242 , A61M2039/2426
摘要： An apparatus for controlling fluid flow through medical devices, specifically for sealing devices which remain in place in the body to provide long term access to the vascular system. Exemplary embodiments of the present invention describe a wedge or other similarly shaped geometrical feature for fixing an elastic component and controlling an internal stress of the elastic component.
摘要翻译：用于控制通过医疗装置的流体流动的装置，特别是用于密封装置，其保持在体内的适当位置以提供对血管系统的长期接近。本发明的示例性实施例描述了用于固定弹性部件并控制弹性部件的内部应力的楔形或其它类似形状的几何特征。

9. 发明申请

US20100297684A1 ACTIVATIBLE DYES 有权
标题翻译：可活动的眼睛
公开(公告)号：US20100297684A1
公开(公告)日：2010-11-25
申请号：US12677962
申请日：2008-09-12
申请人： Stephen C. Miller
发明人： Stephen C. Miller
IPC分类号： C12Q1/02 , C07D498/14 , C07D265/38 , C07D498/22
CPC分类号： C09B19/00 , A61K49/0028 , C09B5/60 , G01N33/5005
摘要： Novel, activatable dyes, such as photoactivatable dyes, e.g., oxazine dyes, are described. Some of the dyes are targeting dyes that can, e.g., target biomolecules, such as polypeptides, proteins, or nucleic acids. Upon activation, such as by irradiation, the novel dyes rapidly turn on their fluorescence and emit light, such as near-IR light with spatial and temporal precision.
摘要翻译：描述了新颖的可活化的染料，例如可光活化的染料，例如恶嗪染料。一些染料是可以例如靶向生物分子的靶向染料，例如多肽，蛋白质或核酸。在激活时，例如通过照射，新染料迅速地开启它们的荧光并发出光，例如具有空间和时间精度的近红外光。

10. 发明授权

US4829452A Small angle image rotation using block transfers 失效
标题翻译：使用块传输的小角度图像旋转
公开(公告)号：US4829452A
公开(公告)日：1989-05-09
申请号：US627995
申请日：1984-07-05
申请人： Sang-Chul Kang , Zoltan Z. Stroll , Stephen C. Miller
发明人： Sang-Chul Kang , Zoltan Z. Stroll , Stephen C. Miller
IPC分类号： G06T3/60
CPC分类号： G06T3/602
摘要： A simplified method for rotating a digital image through a small angle without the need for interpolation is described. The image is divided into small, square blocks, arranged in horizontal rows where each block is exactly to the left or right of the other blocks in the row, and into columns where each block in the column is offset to the right by one pixel with respect to the next higher block. The rotation is then accomplished by moving the lower rows to the left so that the columns are exactly vertical, and by moving the rightmost columns in a downward direction so that each block is one pixel below the block to its left. The result is a rotation of the image through a small angle. There is a considerable simplification gained from not rotating the data within each block which results in a slight distortion of the image, but for small angles, this is not noticeable.
摘要翻译：描述了通过小角度旋转数字图像而不需要插值的简化方法。图像被分成小的方块，排列成水平行，其中每个块恰好在行中的其他块的左侧或右侧，并且被列到列中的每个块向右偏移一个像素的列，尊重下一个更高的块。然后通过将下行移动到左侧使得列完全垂直，并且通过沿向下方向移动最右边的列使得每个块在其左侧的块下方一个像素来实现旋转。结果是图像以小角度旋转。通过不旋转每个块内的数据可以获得相当大的简化，这导致图像的轻微失真，但是对于小角度，这是不明显的。

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