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1. 发明申请

US20090054515A1 SKIN-WHITENING COSMETIC 审中-公开
标题翻译：皮肤化妆品
公开(公告)号：US20090054515A1
公开(公告)日：2009-02-26
申请号：US12162977
申请日：2007-02-06
申请人： Takayuki Katagiri , Kouji Yokoyama , Makoto Kimura , Yuko Saitoh
发明人： Takayuki Katagiri , Kouji Yokoyama , Makoto Kimura , Yuko Saitoh
IPC分类号： A61K31/381 , C07D333/22
CPC分类号： A61K8/4986 , A61K31/381 , A61Q19/02 , C07D333/22
摘要： Disclosed are: a novel skin-whitening agent; and a skin-whitening cosmetic or quasi-drug which is highly effective for prevention/amelioration of melanopathy and is prepared using the skin-whitening agent. The cosmetic contains a compound represented by the general formula (I) and/or a salt thereof as an active ingredient. In the general formula (I), R1 and R2 independently represent a secondary or tertiary alkyl group having 3 to 7 carbon atoms; and R3 represents a hydrogen atom, an alkyl group having 1 to 4 carbon atoms or an alkoxy group having 1 to carbon atoms.
摘要翻译：公开的是：一种新型的皮肤美白剂; 以及对预防/改善黑色素病高度有效的皮肤美白化妆品或准药物，并使用皮肤增白剂制备。化妆品含有由通式（I）表示的化合物和/或其盐作为活性成分。在通式（I）中，R 1和R 2独立地表示碳原子数3〜7的仲或叔烷基。 R3表示氢原子，碳原子数为1〜4的烷基或碳原子数为1的烷氧基。

2. 发明申请

US20110243865A1 MELANIN PRODUCTION INHIBITOR 有权
标题翻译： MELANIN生产抑制剂
公开(公告)号：US20110243865A1
公开(公告)日：2011-10-06
申请号：US13131827
申请日：2009-12-22
申请人： Kouji Yokoyama , Makoto Kimura , Masashi Tamai , Yuko Saitoh , Tomomi Kato , Yu Ikeda
发明人： Kouji Yokoyama , Makoto Kimura , Masashi Tamai , Yuko Saitoh , Tomomi Kato , Yu Ikeda
IPC分类号： A61K8/49 , C07D233/58 , C07D401/06 , A61K8/44 , C07C229/36 , A61K8/34 , C07C43/178 , A61K8/41 , C07C215/20 , C07C43/205 , C07C43/23 , C07C211/03 , C07D207/04 , C07D211/70 , C07D213/36 , C07D207/40 , C07D265/30 , C07D241/04 , A61Q19/02
CPC分类号： A61K8/4946 , A61K8/31 , A61K8/34 , A61K8/41 , A61K8/411 , A61K8/418 , A61K8/44 , A61K8/46 , A61K8/49 , A61K8/4913 , A61K8/4926 , A61K8/494 , A61K2800/74 , A61Q19/02 , C07D207/12 , C07D207/404 , C07D213/30 , C07D213/38 , C07D233/58 , C07D295/03 , C07D295/096 , C07D401/06
摘要： Disclosed is a melanin production inhibitor which has an excellent inhibitory activity on the production of melanin and is highly safe. The melanin production inhibitor comprises a compound represented by general formula (1) (excluding clotrimazole), and/or a pharmacologically acceptable salt thereof. In the formula, A1, A2 and A3 are independently selected from a hydrogen atom, an aryl group which may have a substituent, and an aromatic heterocyclic group which may have a substituent, wherein at least one of A1, A2 and A3 is selected from the aryl group and the aromatic heterocyclic group, the total number of carbon atoms contained in A1, A2 and A3 is 6 to 50 and, when at least two of A1, A2 and A3 represent the aryl groups or the aromatic heterocyclic groups, the adjacent two aryl or aromatic heterocyclic groups may be bound to each other via an alkyl chain or an alkenyl chain to form a ring; m represents an integer of 0 to 2; X represents a hetero atom, a hydrogen atom, or a carbon atom; R1 and R2 are independently selected from a hydrogen atom and an oxo group, wherein when one of R1 and R2 is an oxo group, the other is not present; and R3 is selected from a hydrogen atom, and a C1-8 hydrocarbon group in which one or some of hydrogen atoms or carbon atoms may be substituted by a hetero atom or hetero atoms, wherein the number of R3's present in the compound corresponds to the number of X's and, when two or more R3's are present, the R3's are independently present and the adjacent two R3's may be bound to each other to form, together with X, a ring, and the terminal of R3 may be bound to a carbon atom to which A1, A2 and A3 are bound, thereby forming a ring.
摘要翻译：公开了一种黑色素产生抑制剂，其对黑色素的生成具有优异的抑制活性，并且是高度安全的。黑色素生成抑制剂包含通式（1）表示的化合物（克霉唑除外）和/或其药理学上可接受的盐。在该式中，A1，A2和A3独立地选自氢原子，可以具有取代基的芳基和可以具有取代基的芳族杂环基，其中A1，A2和A3中的至少一个选自芳基和芳香族杂环基时，A1，A2，A3中含有的碳原子总数为6〜50，A1，A2，A3中的至少2个为芳基或芳香族杂环基时，两个芳基或芳族杂环基可以通过烷基链或烯基链彼此结合形成环; m表示0〜2的整数。 X表示杂原子，氢原子或碳原子; R 1和R 2独立地选自氢原子和氧代基，其中当R 1和R 2之一是氧代基时，另一个不存在; 和R3选自氢原子，其中一个或几个氢原子或碳原子可以被杂原子或杂原子取代的C1-8烃基，其中存在于化合物中的R3的数目对应于 X的数目，当存在两个或更多个R3时，R3独立地存在，并且相邻的两个R 3可以彼此结合形成与X一起形成环，并且R 3的末端可以与碳结合与A1，A2和A3结合的原子，从而形成环。

3. 发明授权

US08846012B2 Melanin production inhibitor 有权
标题翻译：黑色素生成抑制剂
公开(公告)号：US08846012B2
公开(公告)日：2014-09-30
申请号：US13131827
申请日：2009-12-22
申请人： Kouji Yokoyama , Makoto Kimura , Masashi Tamai , Yuko Saitoh , Tomomi Kato , Yu Ikeda
发明人： Kouji Yokoyama , Makoto Kimura , Masashi Tamai , Yuko Saitoh , Tomomi Kato , Yu Ikeda
IPC分类号： A61K8/49 , C07D233/58 , C07D401/06 , A61K8/44 , A61K8/41 , A61K8/34 , C07D207/404 , A61Q19/02 , C07D213/38 , C07D213/30 , C07D295/03 , C07D207/12 , C07D295/096
CPC分类号： A61K8/4946 , A61K8/31 , A61K8/34 , A61K8/41 , A61K8/411 , A61K8/418 , A61K8/44 , A61K8/46 , A61K8/49 , A61K8/4913 , A61K8/4926 , A61K8/494 , A61K2800/74 , A61Q19/02 , C07D207/12 , C07D207/404 , C07D213/30 , C07D213/38 , C07D233/58 , C07D295/03 , C07D295/096 , C07D401/06
摘要： Disclosed is a melanin production inhibitor which has an excellent inhibitory activity on the production of melanin and is highly safe. The melanin production inhibitor is represented by general formula (1) (excluding clotrimazole) and/or a pharmacologically acceptable salt thereof. In the formula, A1, A2 and A3 are independently selected from a hydrogen atom, an aryl group which may have a substituent, and an aromatic heterocyclic group which may have a substituent. At least one of A1, A2 and A3 is selected from the aryl group and the aromatic heterocyclic group, the total number of carbon atoms contained in A1, A2 and A3 is 6 to 50 and, when at least two of A1, A2 and A3 represent the aryl groups or the aromatic heterocyclic groups, the adjacent two aryl or aromatic heterocyclic groups may be bound to each other via an alkyl chain or an alkenyl chain to form a ring; m represents an integer of 0 to 2; X represents a hetero atom, a hydrogen atom, or a carbon atom; R1 and R2 are independently selected from a hydrogen atom and an oxo group. When one of R1 and R2 is an oxo group, the other is not present. R3 is selected from a hydrogen atom, and a C1-8 hydrocarbon group in which one or some of hydrogen atoms or carbon atoms may be substituted by a hetero atom or hetero atoms. The number of R3's present in the compound corresponds to X and, when two or more R3's are present, the R3's are independently present and the adjacent two R3's may be bound to each other to form, together with X, a ring, and the terminal of R3 may be bound to a carbon atom to which A1, A2 and A3 are bound, thereby forming a ring.
摘要翻译：公开了一种黑色素产生抑制剂，其对黑色素的生成具有优异的抑制活性，并且是高度安全的。黑色素产生抑制剂由通式（1）表示（不包括克霉唑）和/或其药理学上可接受的盐。在该式中，A1，A2和A3独立地选自氢原子，可以具有取代基的芳基和可以具有取代基的芳族杂环基。 A1，A2和A3中的至少一个选自芳基和芳族杂环基，A1，A2和A3中所含的碳原子总数为6〜50，A1，A2和A3中的至少2个表示芳基或芳族杂环基，相邻的两个芳基或芳族杂环基可以通过烷基链或烯基链彼此结合形成环; m表示0〜2的整数。 X表示杂原子，氢原子或碳原子; R 1和R 2独立地选自氢原子和氧代基。当R1和R2中的一个是氧代基时，另一个不存在。 R3选自氢原子和碳原子数为1〜8的烃基，其中一个或几个氢原子或碳原子可以被杂原子或杂原子取代。化合物中存在的R3的数目对应于X，并且当存在两个或更多个R 3时，R 3独立地存在，并且相邻的两个R 3可以彼此结合形成与X一起形成环，并且末端的R3可以结合到与A1，A2和A3结合的碳原子上，从而形成环。

4. 发明授权

US07157996B2 Electromagnetic switching device 有权
标题翻译：电磁开关装置
公开(公告)号：US07157996B2
公开(公告)日：2007-01-02
申请号：US10535337
申请日：2004-07-01
申请人： Hideki Enomoto , Riichi Uotome , Kouji Yokoyama , Katsuyoshi Kamioka
发明人： Hideki Enomoto , Riichi Uotome , Kouji Yokoyama , Katsuyoshi Kamioka
IPC分类号： H01H67/02
CPC分类号： H01H50/02 , H01H50/04 , H01H50/30 , H01H2009/0278
摘要： In the electromagnetic switching device, it is possible to miniaturize and have low costs, have quiet operation noise, and also quickly extinguish the arc. The electromagnetic switching device has an electromagnetic actuator with a movable iron core, a pair of fixed terminals that respectively have a fixed contact point, a movable contact that has movable contact points on the right and left ends, a shaft, and an enclosing component that holds the movable contact points and the fixed contact points. The pair of movable contact points respectively contact with and detach from the pair of fixed contact points, and the pair of fixed contact points respectively conduct each other and are insulated again through the shaft by moving the movable iron core along the axis using the electric magnetic actuator. A quasi-hermetically sealed space, which is the extinguishing space, is formed by the enclosing component and a first yoke. A potting compound is charged, into the space between a body and the quasi hermitically sealed space.
摘要翻译：在电磁开关装置中，可以小型化，成本低，操作噪音小，并且电弧也快速熄灭。电磁开关装置具有电磁致动器，其具有可动铁芯，分别具有固定接触点的一对固定端子，在左右两端具有可动接触点的可动触头，轴和包围部件，保持活动触点和固定触点。所述一对可动接触点分别与所述一对固定接触点接触和分离，并且所述一对固定接触点分别相互导通并且通过使用所述电磁铁沿所述轴移动所述可动铁芯而再次通过所述轴绝缘执行器。作为灭火空间的准气密密封空间由封闭部件和第一轭形成。将灌封化合物装入身体与准密封空间之间的空间。

5. 发明申请

US20100126075A1 OPEN/CLOSE CONTROL SYSTEM FOR INSPECTION LID 有权
标题翻译：检查灯开/关控制系统
公开(公告)号：US20100126075A1
公开(公告)日：2010-05-27
申请号：US12597987
申请日：2008-06-18
申请人： Haruo Akoshita , Mitsuaki Murota , Minoru Nakao , Mamoru Tanaka , Kouji Yokoyama , Kazuhiro Yoshizawa
发明人： Haruo Akoshita , Mitsuaki Murota , Minoru Nakao , Mamoru Tanaka , Kouji Yokoyama , Kazuhiro Yoshizawa
IPC分类号： E05F15/10 , E05F11/54 , E05B47/00
CPC分类号： E05B13/001 , B61D19/02 , B61D19/023 , E05B47/0002 , E05B47/0004 , E05B47/026 , E05B77/50 , E05B77/54 , E05B83/363 , E05B2047/0073 , E05F15/40 , E05Y2400/52 , E05Y2800/25 , E05Y2800/254 , E05Y2800/424 , E05Y2900/00 , E05Y2900/51 , E05Y2900/53 , Y10T70/5611
摘要： An open/close control system for an inspection lid adapted not to open while a vehicle travels. The open/close control system has emergency release means which disables power transmission of drive means for opening and closing a side entrance/exit door of a railway vehicle. The emergency release means is installed in a space inside a wall surface inside the vehicle, and the space can be opened and closed by the inspection lid. The emergency release means has locking devices provided in the space inside the wall surface in order to restrict rotation of the inspection lid, and also has an open/close controller for detecting traveling of the railway vehicle to actuate the locking device.
摘要翻译：用于检查盖的开/关控制系统，其适于在车辆行驶时不打开。开/关控制系统具有紧急释放装置，其禁止用于打开和关闭铁路车辆的侧入口/出口的驱动装置的动力传递。紧急释放装置安装在车辆内部的壁面内的空间中，并且可以通过检查盖打开和关闭空间。紧急释放装置具有设置在壁表面内的空间中的锁定装置，以便限制检查盖的旋转，并且还具有用于检测铁路车辆行驶以致动锁定装置的打开/关闭控制器。

6. 发明授权

US07048574B2 Resilient contact structure with bypass wire and camera having such contact 有权
标题翻译：弹性接触结构与旁路线和相机具有这种接触
公开(公告)号：US07048574B2
公开(公告)日：2006-05-23
申请号：US10863200
申请日：2004-06-09
申请人： Junichi Shinohara , Ikuya Tsurukawa , Akemi Miyoshi , Kouji Yokoyama
发明人： Junichi Shinohara , Ikuya Tsurukawa , Akemi Miyoshi , Kouji Yokoyama
IPC分类号： H01R11/20
CPC分类号： G03B17/02 , H01M2/1022 , H01M2/204
摘要： A contact structure having a spring with electro conductivity. The spring is fixed at one inner end side of a battery housing by engaging a plurality of inflection parts of the spring to one end side of the battery housing. The spring urges the battery to the other end side of a battery housing. An end portion on movable side end of the spring is extended toward an opening on a lateral face of the battery housing. The end portion is formed on a contact side end of the spring that is contacted with the battery, and is connected to one end side of a bypassing lead wire. An end portion on the fixed side end of the spring is connected to the other end side of the bypassing lead wire. The end portion of the fixed side end of the spring is connected to a power source lead wire. A free end of the contact movable side end can be bent away from the battery to provide a solder connection to the bypass wire.
摘要翻译：具有导电弹簧的接触结构。弹簧通过将弹簧的多个弯曲部分接合到电池壳体的一端侧而固定在电池壳体的一个内端侧。弹簧将电池推向电池壳体的另一端。弹簧的可动侧端部的端部朝向电池壳体的侧面上的开口延伸。端部形成在与电池接触的弹簧的接触侧端部，并且连接到旁路引线的一端侧。弹簧的固定侧端部的端部与旁路引线的另一端侧连接。弹簧的固定侧端部的端部连接到电源引线。接触可动侧端的自由端可以从电池弯曲，以提供与旁路线的焊接连接。

7. 发明申请

US20060050466A1 Electromagnetic switching device 有权
标题翻译：电磁开关装置
公开(公告)号：US20060050466A1
公开(公告)日：2006-03-09
申请号：US10535337
申请日：2004-07-01
申请人： Hideki Enomoto , Riichi Uotome , Kouji Yokoyama , Katsuyoshi Kamioka
发明人： Hideki Enomoto , Riichi Uotome , Kouji Yokoyama , Katsuyoshi Kamioka
IPC分类号： H01H47/00
CPC分类号： H01H50/02 , H01H50/04 , H01H50/30 , H01H2009/0278
摘要： In the electromagnetic switching device, it is possible to miniaturize and have low costs, have quiet operation noise, and also quickly extinguish the arc. The electromagnetic switching device has an electromagnetic actuator with a movable iron core, a pair of fixed terminals that respectively have a fixed contact point, a movable contact that has movable contact points on the right and left ends, a shaft, and an enclosing component that holds the movable contact points and the fixed contact points. The pair of movable contact points respectively contact with and detach from the pair of fixed contact points, and the pair of fixed contact points respectively conduct each other and are insulated again through the shaft by moving the movable iron core along the axis using the electric magnetic actuator. A quasi-hermetically sealed space, which is the extinguishing space, is formed by the enclosing component and a first yoke. A potting compound is charged, into the space between a body and the quasi hermitically sealed space.
摘要翻译：在电磁开关装置中，可以小型化，成本低，操作噪音小，并且电弧也快速熄灭。电磁开关装置具有电磁致动器，其具有可动铁芯，分别具有固定接触点的一对固定端子，在左右两端具有可动接触点的可动触头，轴和包围部件，保持活动触点和固定触点。所述一对可动接触点分别与所述一对固定接触点接触和分离，并且所述一对固定接触点分别相互导通并且通过使用所述电磁铁沿所述轴移动所述可动铁芯而再次通过所述轴绝缘执行器。作为灭火空间的准气密密封空间由封闭部件和第一轭形成。将灌封化合物加入到身体与准密封空间之间的空间中。

8. 发明授权

US08677855B2 Conveyance arm and conveyance robot with same 有权
标题翻译：输送臂和运输机器人相同
公开(公告)号：US08677855B2
公开(公告)日：2014-03-25
申请号：US13480028
申请日：2012-05-24
申请人： Kouji Yokoyama
发明人： Kouji Yokoyama
IPC分类号： B25J18/00
CPC分类号： H01L21/67742 , B25J9/1065 , H01L21/67766 , Y10T74/20305 , Y10T74/20329
摘要： First and second parallel link mechanisms 36, 38 are connected via a short link 35 arranged on a rotational angle transmission mechanism 29 so that a rotation applied to the first parallel link mechanism 36 is transmitted to the second parallel link mechanism 38 via the rotational angle transmission mechanism 29. The rotational angle transmission mechanism 29, the second parallel link mechanism 38 and the driven side link of the first parallel link mechanism 36 are horizontally supported by the drive side link 30 of the first parallel link mechanism 36. The rotational angle transmission mechanism 29 transmits the rotational angle applied to the drive side link 30 of the first parallel link mechanism 36 to the drive side link 32 of the second parallel link mechanism 38 supported by the drive side link 30 via the guide means that is parallel to the short link 35.
摘要翻译：第一和第二平行连杆机构36,38经由布置在旋转角传动机构29上的短连杆35连接，使得施加到第一平行连杆机构36的旋转经由旋转角度传递传递到第二平行连杆机构38 第一平行连杆机构36的旋转角度传递机构29，第二平行连杆机构38和从动侧连杆由第一平行连杆机构36的驱动侧连杆30水平地支撑。旋转角度传递机构 29通过平行于短路的引导装置将施加到第一并联连杆机构36的驱动侧连杆30的旋转角度传递到由驱动侧连杆30支撑的第二平行连杆机构38的驱动侧连杆32 35。

9. 发明授权

US06586633B1 Amine derivatives 失效
标题翻译：胺衍生物
公开(公告)号：US06586633B1
公开(公告)日：2003-07-01
申请号：US09762678
申请日：2001-04-05
申请人： Masayuki Yuasa , Yukio Kawazu , Toshimitsu Suzuki , Toshiro Majima , Takao Itoh , Takuji Nakashima , Akira Nozawa , Hiroyuki Takimoto , Kouji Yokoyama
发明人： Masayuki Yuasa , Yukio Kawazu , Toshimitsu Suzuki , Toshiro Majima , Takao Itoh , Takuji Nakashima , Akira Nozawa , Hiroyuki Takimoto , Kouji Yokoyama
IPC分类号： C07C21121
CPC分类号： C07C215/28 , C07C17/14 , C07C17/16 , C07C45/004 , C07C45/565 , C07C45/63 , C07C211/21 , C07C211/27 , C07C211/28 , C07C211/29 , C07C211/35 , C07C215/30 , C07C223/02 , C07C225/16 , C07C225/26 , C07C2601/02 , C07C25/02 , C07C49/76 , C07C47/546 , C07C49/80
摘要： The present invention relates to amine derivatives represented by formula (1) or salts thereof. R3 represents C1-C3 alkyl, hydroxylated C1-C5 alkyl, C1-C5 acyl; C2-C5 alkenyl, or a halogen atom; and k, l, and m are each an integer of 1 to 4.) Exhibiting excellent antifungal effect, these compounds are highly useful as antifungal agents, antifungal compositions, drugs, etc.
摘要翻译：本发明涉及由式（1）表示的胺衍生物或其盐.R 3表示C 1 -C 3烷基，羟基化的C 1 -C 5烷基，C 1 -C 5酰基; C 2 -C 5烯基或卤素原子; 并且k，l和m各自为1〜4的整数。）具有优异的抗真菌效果，这些化合物作为抗真菌剂，抗真菌剂，药物等是非常有用的。

10. 发明授权

US06573939B1 Digital camera having synchronized movement of lens and flash 失效
标题翻译：数码相机具有镜头和闪光灯的同步运动
公开(公告)号：US06573939B1
公开(公告)日：2003-06-03
申请号：US09033073
申请日：1998-03-02
申请人： Kouji Yokoyama
发明人： Kouji Yokoyama
IPC分类号： H04N5225
CPC分类号： H04N5/2251 , H04N5/2256
摘要： A digital camera having a camera body and a lens assembly within an imaging unit which is rotatably connected to the camera body. Rotation of the imaging unit containing the lens assembly with respect to the position of the camera body causes the flash within the camera body to follow the direction at which the lens assembly is aimed. If the camera has a self-portrait mode in which the lens assembly can be aimed backwards at the user of the camera but the flash cannot be aimed backwards due to constraints of the camera body or if the flash cannot cover the complete angular range of the lens, a mechanism is utilized to couple the movement of the lens and the flash over a limited range of movement of the lens. Springs, concentric gears attached by springs, or a clutch mechanism may be utilized to selectively couple the flash with the lens rotation. By separating the flash from the lens, the red-eye phenomena will be reduced.
摘要翻译：一种数码相机，其具有可旋转地连接到照相机主体的成像单元内的照相机主体和透镜组件。包含镜头组件的成像单元相对于照相机主体的位置的旋转导致照相机主体内的闪光灯遵循透镜组件瞄准的方向。如果相机具有自拍模式，其中镜头组件可以向后瞄准相机的用户，但是由于相机机身的限制，闪光灯不能向后瞄准，或者如果闪光灯不能覆盖相机的整个角度范围透镜，在透镜的有限的移动范围内利用机构来耦合透镜和闪光体的运动。通过弹簧连接的弹簧，同心齿轮或离合器机构可用于选择性地将闪光灯与透镜旋转耦合。通过将闪光灯与透镜分开，红眼现象将会降低。

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