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1. 发明授权

US08648557B2 Drive control signal generating circuit 有权
标题翻译：驱动控制信号发生电路
公开(公告)号：US08648557B2
公开(公告)日：2014-02-11
申请号：US13247050
申请日：2011-09-28
申请人： Takashi Ogawa , Takahisa Nakai , Tsutomu Murata
发明人： Takashi Ogawa , Takahisa Nakai , Tsutomu Murata
IPC分类号： H02K5/00
CPC分类号： H02P6/085 , H02P6/26
摘要： A drive control signal generating circuit that generates a drive control signal for driving a motor includes an output control circuit that includes a flip-flop in which a state changes by a rotational state signal of the motor crossing a reference value and generates a motor drive control signal according to the state of the flip-flop, a clock generating circuit that generates a clock that defines a time of reading data in the flip-flop of the output control circuit; and a PWM conversion circuit that PWM-converts the drive control signal using the clock as a PWM signal. The clock has a frequency in which the output control circuit operates and has a duty ratio of the PWM signal.
摘要翻译：产生用于驱动电动机的驱动控制信号的驱动控制信号产生电路包括：输出控制电路，包括触发器，其中状态由电动机的旋转状态信号变化而与参考值相交，并产生电动机驱动控制信号根据触发器的状态产生时钟产生电路，其生成定义在输出控制电路的触发器中读取数据的时间的时钟; 以及使用该时钟作为PWM信号对驱动控制信号进行PWM转换的PWM变换电路。时钟具有输出控制电路工作的频率，并具有PWM信号的占空比。

2. 发明申请

US20120081049A1 DRIVE CONTROL SIGNAL GENERATING CIRCUIT 有权
标题翻译：驱动控制信号发生电路
公开(公告)号：US20120081049A1
公开(公告)日：2012-04-05
申请号：US13247050
申请日：2011-09-28
申请人： Takashi Ogawa , Takahisa Nakai , Tsutomu Murata
发明人： Takashi Ogawa , Takahisa Nakai , Tsutomu Murata
IPC分类号： H02P6/08
CPC分类号： H02P6/085 , H02P6/26
摘要： PWM conversion is efficiently executed. An output control circuit comprises a flip-flop which reads crossing of a reference value by a rotational state signal from a motor, and generates a motor drive control signal according to a state of the flip-flop. A clock generator generates a clock which defines a time of reading data in the flip-flop of the output control circuit. A PWM conversion circuit PWM-converts the drive control signal using the clock as a PWM signal.
摘要翻译： PWM转换有效执行。输出控制电路包括触发器，其触发参考值与来自电动机的旋转状态信号的交叉，并根据触发器的状态生成电动机驱动控制信号。时钟发生器产生定义在输出控制电路的触发器中读取数据的时间的时钟。 PWM转换电路使用时钟作为PWM信号对驱动控制信号进行PWM转换。

3. 发明授权

US08502530B2 Offset cancelling circuit 有权
标题翻译：偏移消除电路
公开(公告)号：US08502530B2
公开(公告)日：2013-08-06
申请号：US12795779
申请日：2010-06-08
申请人： Takashi Ogawa , Hironori Terazawa , Takahisa Nakai
发明人： Takashi Ogawa , Hironori Terazawa , Takahisa Nakai
IPC分类号： G01R33/06
CPC分类号： G01R33/07 , G01B7/003 , G01B7/30 , G01D3/032 , G01D5/142 , G01R33/0035 , G01R33/072
摘要： In an offset cancelling circuit of a Hall element, a voltage is applied from four directions and from outside such that a current flowing in the Hall element is switched by 90°, to set a first state through a fourth state, and output voltages of the Hall element in the first state through the fourth state are averaged.
摘要翻译：在霍尔元件的偏移消除电路中，从四个方向和外部施加电压使得在霍尔元件中流动的电流被切换90°，以将第一状态设置为第四状态，并且输出电压第一状态到第四状态的霍尔元件被平均化。

4. 发明授权

US07915022B2 Carbonyl reductase, gene thereof and method of using the same 有权
标题翻译：羰基还原酶，其基因及其使用方法
公开(公告)号：US07915022B2
公开(公告)日：2011-03-29
申请号：US12840026
申请日：2010-07-20
申请人： Noriyuki Kizaki , Miho Yano , Masashiro Funaki , Teruaki Takesue , Yoshihiko Yasohara , Souichi Morikawa , Takahisa Nakai , Michihiko Kataoka , Sakayu Shimizu
发明人： Noriyuki Kizaki , Miho Yano , Masashiro Funaki , Teruaki Takesue , Yoshihiko Yasohara , Souichi Morikawa , Takahisa Nakai , Michihiko Kataoka , Sakayu Shimizu
IPC分类号： C12N9/02 , C07K14/00 , C12P21/00 , C12P7/16 , C12P7/02 , C12Q1/26
CPC分类号： C12P13/02 , C12N9/0006 , C12P41/002
摘要： The present invention relates to a polypeptide having an activity to asymmetrically reduce (3S)-1-chloro-3-tert-butoxycarbonylamino-4-phenyl-2-butanone to produce (2R,3S)-1-chloro-3-tert-butoxycarbonylamino-4-phenyl-2-butanol isolated from a microorganism belonging to the genus Ogataea, a DNA encoding the polypeptide and a transformant that produces the polypeptide. The present invention moreover relates to a method of producing (2R,3S)-1-chloro-3-tert-butoxycarbonylamino-4-phenyl-2-butanol utilizing the polypeptide or the transformant.Using the polypeptide or transformant of the present invention, optically active alcohols such as (2R,3S)-1-chloro-3-tert-butoxycarbonylamino-4-phenyl-2-butanol and the like can be produced efficiently.
摘要翻译：本发明涉及具有不对称降低（3S）-1-氯-3-叔丁氧基羰基氨基-4-苯基-2-丁酮的活性以产生（2R，3S）-1-氯-3-叔丁氧基羰基氨基-4- 从属于Ogataea的微生物分离的丁氧基羰基氨基-4-苯基-2-丁醇，编码多肽的DNA和产生多肽的转化体。本发明还涉及利用多肽或转化体制备（2R，3S）-1-氯-3-叔丁氧基羰基氨基-4-苯基-2-丁醇的方法。使用本发明的多肽或转化体，可以有效地制备光学活性醇如（2R，3S）-1-氯-3-叔丁氧基羰基氨基-4-苯基-2-丁醇等。

5. 发明授权

US07794993B2 Carbonyl reductase, gene thereof and method of using the same 有权
标题翻译：羰基还原酶，其基因及其使用方法
公开(公告)号：US07794993B2
公开(公告)日：2010-09-14
申请号：US11659481
申请日：2005-08-01
申请人： Noriyuki Kizaki , Miho Yano , Masahiro Funaki , Teruaki Takesue , Yoshihiko Yasohara , Souichi Morikawa , Takahisa Nakai , Michihiko Kataoka , Sakayu Shimizu
发明人： Noriyuki Kizaki , Miho Yano , Masahiro Funaki , Teruaki Takesue , Yoshihiko Yasohara , Souichi Morikawa , Takahisa Nakai , Michihiko Kataoka , Sakayu Shimizu
IPC分类号： C07H21/00 , C12N15/00 , C12N5/10 , C12N1/21 , C12P7/16 , C12P21/00 , C12N9/02 , C07K14/00
CPC分类号： C12P13/02 , C12N9/0006 , C12P41/002
摘要： The present invention relates to a polypeptide having an activity to asymmetrically reduce (3S)-1-chloro-3-tert-butoxycarbonylamino-4-phenyl-2-butanone to produce (2R,3S)-1-chloro-3-tert-butoxycarbonylamino-4-phenyl-2-butanol isolated from a microorganism belonging to the genus Ogataea, a DNA encoding the polypeptide and a transformant that produces the polypeptide. The present invention moreover relates to a method of producing (2R,3S)-1-chloro-3-tert-butoxycarbonylamino-4-phenyl-2-butanol utilizing the polypeptide or the transformant. Using the polypeptide or transformant of the present invention, optically active alcohols such as (2R,3S)-1-chloro-3-tert-butoxycarbonylamino-4-phenyl-2-butanol and the like can be produced efficiently.
摘要翻译：本发明涉及具有不对称还原（3S）-1-氯-3-叔丁氧基羰基氨基-4-苯基-2-丁酮的活性以产生（2R，3S）-1-氯-3-叔丁氧基羰基氨基-4- 从属于Ogataea的微生物分离的丁氧基羰基氨基-4-苯基-2-丁醇，编码多肽的DNA和产生多肽的转化体。本发明还涉及利用多肽或转化体制备（2R，3S）-1-氯-3-叔丁氧基羰基氨基-4-苯基-2-丁醇的方法。使用本发明的多肽或转化体，可以有效地制备光学活性醇如（2R，3S）-1-氯-3-叔丁氧基羰基氨基-4-苯基-2-丁醇等。

6. 发明申请

US20090209623A1 Anti-sense nucleic acid derived from organism 审中-公开
标题翻译：来自生物体的反义核酸
公开(公告)号：US20090209623A1
公开(公告)日：2009-08-20
申请号：US11989301
申请日：2006-07-24
申请人： Jon Tomono , Souichi Morikawa , Takahisa Nakai
发明人： Jon Tomono , Souichi Morikawa , Takahisa Nakai
IPC分类号： A61K31/7088 , C07H21/04 , A61K48/00
CPC分类号： A61K8/606 , A61K31/7088 , A61K48/00 , A61Q5/00 , A61Q19/02 , A61Q19/08 , C12N15/111 , C12N15/1137 , C12N2310/11 , C12N2330/30
摘要： Disclosed are: a method for producing an anti-sense nucleic acid which has a wide variation in nucleotide sequences and excellent anti-sense properties at a low cost in a simple manner and in a large scale; and a cosmetic composition or pharmaceutical composition comprising the anti-sense nucleic acid. A method is discovered which can produce a low molecular weight nucleic acid having anti-sense properties from a nucleic acid starting material derived from an organism at a high yield by using a probe nucleic acid having at least a part of the nucleotide sequence of a target gene. An anti-sense nucleic acid produced by using a nucleic acid derived from an organism as a starting material; and a method for producing the anti-sense nucleic acid.
摘要翻译：本发明公开了以简单的方式和大规模生产具有较低成本的核苷酸序列变异性和抗反应性优异的反义核酸的方法。以及包含所述反义核酸的化妆品组合物或药物组合物。通过使用具有目标的核苷酸序列的至少一部分的探针核酸，发现能够以高产率从来自生物体的核酸起始物质产生具有反义性的低分子量核酸的方法基因。通过使用来自生物体的核酸作为起始原料而产生的反义核酸; 和反义核酸的制造方法。

7. 发明申请

US20090003093A1 FUSE READING CIRCUIT 有权
标题翻译：保险丝读取电路
公开(公告)号：US20090003093A1
公开(公告)日：2009-01-01
申请号：US11863693
申请日：2007-09-28
申请人： Yuichi Matsuo , Takahisa Nakai
发明人： Yuichi Matsuo , Takahisa Nakai
IPC分类号： G11C17/16 , G11C7/00
CPC分类号： G11C17/16 , G11C17/18 , G11C29/027 , G11C29/028
摘要： Correction data is written in fuse circuits of q bits. A reading circuit sequentially reads information of the fuse circuits through a selector and writes the information in a storage circuit. Therefore, read data is output from the storage circuit in parallel.
摘要翻译：校正数据写入q位的熔丝电路。读取电路通过选择器顺序读取熔丝电路的信息，并将该信息写入存储电路。因此，并行地从存储电路输出读取数据。

8. 发明授权

US07782648B2 Fuse reading circuit 有权
标题翻译：保险丝读取电路
公开(公告)号：US07782648B2
公开(公告)日：2010-08-24
申请号：US11863693
申请日：2007-09-28
申请人： Yuichi Matsuo , Takahisa Nakai
发明人： Yuichi Matsuo , Takahisa Nakai
IPC分类号： G11C17/00
CPC分类号： G11C17/16 , G11C17/18 , G11C29/027 , G11C29/028
摘要： Correction data is written in fuse circuits of q bits. A reading circuit sequentially reads information of the fuse circuits through a selector and writes the information in a storage circuit. Therefore, read data is output from the storage circuit in parallel.
摘要翻译：校正数据写入q位的熔丝电路。读取电路通过选择器顺序读取熔丝电路的信息，并将该信息写入存储电路。因此，并行地从存储电路输出读取数据。

9. 发明申请

US20080261281A1 Novel Carbonyl Reductase, Gene Thereof and Method of Using the Same 有权
标题翻译：新型羰基还原酶，其基因及其使用方法
公开(公告)号：US20080261281A1
公开(公告)日：2008-10-23
申请号：US11659481
申请日：2005-08-01
申请人： Noriyuki Kizaki , Miho Yano , Masahiro Funaki , Teruaki Takesue , Yoshihiko Yasohara , Souichi Morikawa , Takahisa Nakai , Michihiko Kataoka , Sakayu Shimizu
发明人： Noriyuki Kizaki , Miho Yano , Masahiro Funaki , Teruaki Takesue , Yoshihiko Yasohara , Souichi Morikawa , Takahisa Nakai , Michihiko Kataoka , Sakayu Shimizu
IPC分类号： C12N9/14 , C12N15/52 , C12N1/21 , C12P13/02
CPC分类号： C12P13/02 , C12N9/0006 , C12P41/002
摘要： The present invention relates to a polypeptide having an activity to asymmetrically reduce (3S)-1-chloro-3-tert-butoxycarbonylamino-4-phenyl-2-butanone to produce (2R,3S)-1-chloro-3-tert-butoxycarbonylamino-4-phenyl-2-butanol isolated from a microorganism belonging to the genus Ogataea, a DNA encoding the polypeptide and a transformant that produces the polypeptide. The present invention moreover relates to a method of producing (2R,3S)-1-chloro-3-tert-butoxycarbonylamino-4-phenyl-2-butanol utilizing the polypeptide or the transformant.Using the polypeptide or transformant of the present invention, optically active alcohols such as (2R,3S)-1-chloro-3-tert-butoxycarbonylamino-4-phenyl-2-butanol and the like can be produced efficiently.
摘要翻译：本发明涉及具有不对称还原（3S）-1-氯-3-叔丁氧基羰基氨基-4-苯基-2-丁酮的活性以产生（2R，3S）-1-氯-3-叔丁氧基羰基氨基-4- 从属于Ogataea的微生物分离的丁氧基羰基氨基-4-苯基-2-丁醇，编码多肽的DNA和产生多肽的转化体。本发明还涉及利用多肽或转化体制备（2R，3S）-1-氯-3-叔丁氧基羰基氨基-4-苯基-2-丁醇的方法。使用本发明的多肽或转化体，可以有效地制备光学活性醇如（2R，3S）-1-氯-3-叔丁氧基羰基氨基-4-苯基-2-丁醇等。

10. 发明申请

US20090253794A1 Fibroblast Activator, Collagen Production Promoter, Collagen Contraction Promoter, Hyaluronic Acid Production Promoter, ATP Production Promoter, Melanin Formation Inhibitor, and Agent for External Application to the Skin 审中-公开
标题翻译：成纤维细胞激活剂，胶原生成促进剂，胶原收缩启动子，透明质酸生产促进剂，ATP生产促进剂，黑色素形成抑制剂和外用于皮肤的药剂
公开(公告)号：US20090253794A1
公开(公告)日：2009-10-08
申请号：US11989194
申请日：2006-07-21
申请人： Jun Tomono , Takahisa Nakai , Toshihide Fujii
发明人： Jun Tomono , Takahisa Nakai , Toshihide Fujii
IPC分类号： A61K31/195
CPC分类号： A61Q19/08 , A61K8/44 , A61K31/195 , A61Q19/02
摘要： The present invention is a fibroblast activator, collagen production promoter, collagen contraction promoter, hyaluronic acid production promoter, ATP production promoter or melanin formation suppressor, which contains, as an active ingredient, at least one kind of compound selected from the group consisting of conagenin, a conagenin derivative, and a pharmaceutically acceptable salt thereof, as well as a composition (skin external preparation, cosmetic, pharmaceutical product or food, which is a composition for the improvement of wrinkles or a whitening composition) containing such activator, promoter or melanin formation suppressor.According to the present invention, a safe skin external preparation, cosmetic (cosmetic composition), pharmaceutical product or food, which shows a high wrinkle improving effect, can be provided, and a safe skin external preparation, cosmetic (cosmetic composition), pharmaceutical product or food, which shows a high whitening effect can be provided.
摘要翻译：本发明是一种成纤维细胞激活剂，胶原产生促进剂，胶原蛋白收缩促进剂，透明质酸产生促进剂，ATP生产促进剂或黑色素形成抑制剂，其含有至少一种选自下列基团的化合物作为活性成分：，配子衍生物及其药学上可接受的盐，以及含有这种活化剂，促进剂或黑色素的组合物（皮肤外用制剂，化妆品，药物产品或食品，其是用于改善皱纹或美白组合物的组合物）形成抑制器。根据本发明，可以提供显示出高皱纹改善效果的安全皮肤外用剂，化妆品（化妆品组合物），药品或食品，以及安全的皮肤外用剂，化妆品（化妆品组合物），药品或食物，其可以提供高的美白效果。

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